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MX2020004516A - Metodos y composiciones para la dosificacion de celulas t con receptor de antigeno quimerico alogenicas. - Google Patents

Metodos y composiciones para la dosificacion de celulas t con receptor de antigeno quimerico alogenicas.

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Publication number
MX2020004516A
MX2020004516A MX2020004516A MX2020004516A MX2020004516A MX 2020004516 A MX2020004516 A MX 2020004516A MX 2020004516 A MX2020004516 A MX 2020004516A MX 2020004516 A MX2020004516 A MX 2020004516A MX 2020004516 A MX2020004516 A MX 2020004516A
Authority
MX
Mexico
Prior art keywords
methods
compositions
cells
antigen receptor
chimeric antigen
Prior art date
Application number
MX2020004516A
Other languages
English (en)
Inventor
Cyril Alkis Konto
Amina Zinai
Original Assignee
Allogene Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allogene Therapeutics Inc filed Critical Allogene Therapeutics Inc
Publication of MX2020004516A publication Critical patent/MX2020004516A/es

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    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
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Abstract

La presente descripción se refiere a dosificaciones para el tratamiento de pacientes humanos susceptibles o diagnosticados con una enfermedad, tal como cáncer. Se proporcionan métodos para administrar células T con receptor de antígeno quimérico (CAR). También se proporcionan composiciones y artículos de fabricación para usar en los métodos.
MX2020004516A 2017-10-31 2018-10-30 Metodos y composiciones para la dosificacion de celulas t con receptor de antigeno quimerico alogenicas. MX2020004516A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762579426P 2017-10-31 2017-10-31
US201862716898P 2018-08-09 2018-08-09
US201862750215P 2018-10-24 2018-10-24
PCT/US2018/058288 WO2019089650A1 (en) 2017-10-31 2018-10-30 Methods and compositions for dosing of allogeneic chimeric antigen receptor t cells

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MX2020004516A true MX2020004516A (es) 2020-10-20

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KR (1) KR20200094147A (es)
CN (2) CN111886015B (es)
AU (2) AU2018360566C1 (es)
BR (1) BR112020008428A2 (es)
CA (1) CA3079747A1 (es)
CO (1) CO2020006443A2 (es)
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AU2020267057A1 (en) 2019-04-30 2021-11-18 Crispr Therapeutics Ag Allogeneic cell therapy of B cell malignancies using genetically engineered T cells targeting CD19
CA3160096A1 (en) * 2019-12-06 2021-06-10 Bruce J. Mccreedy Jr. Methods for cancer immunotherapy
US12378521B2 (en) 2020-04-15 2025-08-05 Amgen Inc. Method for enhancing production of genetically engineered autologous T cells
US12241086B2 (en) 2020-04-15 2025-03-04 Amgen Inc. Process for generating genetically engineered autologous T cells
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