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MX2018001825A - Variantes y conjugados de albumina. - Google Patents

Variantes y conjugados de albumina.

Info

Publication number
MX2018001825A
MX2018001825A MX2018001825A MX2018001825A MX2018001825A MX 2018001825 A MX2018001825 A MX 2018001825A MX 2018001825 A MX2018001825 A MX 2018001825A MX 2018001825 A MX2018001825 A MX 2018001825A MX 2018001825 A MX2018001825 A MX 2018001825A
Authority
MX
Mexico
Prior art keywords
conjugates
albumin variants
albumin
variants
albumins
Prior art date
Application number
MX2018001825A
Other languages
English (en)
Inventor
Ann Delahay Karen
John Arthur Finnis Christopher
Michael Nicholls Karl
Original Assignee
Albumedix As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Albumedix As filed Critical Albumedix As
Publication of MX2018001825A publication Critical patent/MX2018001825A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A61K38/385—Serum albumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invención se refiere a las albúminas capacitadas para la conjugación y a los polipéptidos relacionados con la albúmina, así como a sus conjugados con por lo menos una fracción, y a los polinucleótidos que los codifican.
MX2018001825A 2015-08-20 2016-08-19 Variantes y conjugados de albumina. MX2018001825A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15181822 2015-08-20
PCT/EP2016/069748 WO2017029407A1 (en) 2015-08-20 2016-08-19 Albumin variants and conjugates

Publications (1)

Publication Number Publication Date
MX2018001825A true MX2018001825A (es) 2018-05-07

Family

ID=56842796

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018001825A MX2018001825A (es) 2015-08-20 2016-08-19 Variantes y conjugados de albumina.

Country Status (10)

Country Link
US (3) US10633428B2 (es)
EP (1) EP3337816B1 (es)
JP (1) JP7007261B2 (es)
CN (1) CN108137674B (es)
AU (1) AU2016308504A1 (es)
BR (1) BR112018003179A2 (es)
CA (1) CA2989966C (es)
IL (1) IL256627A (es)
MX (1) MX2018001825A (es)
WO (1) WO2017029407A1 (es)

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MX2018001825A (es) 2015-08-20 2018-05-07 Albumedix As Variantes y conjugados de albumina.
ES2906997T3 (es) 2017-06-20 2022-04-21 Albumedix Ltd Cepas de expresión de proteínas mejoradas
CN107082815A (zh) * 2017-06-28 2017-08-22 杭州皓阳生物技术有限公司 一种fsh‑hsa融合蛋白及其制备方法
CA3072634A1 (en) * 2017-10-18 2019-04-25 Sabine Rauth Human serum albumin variants and uses thereof
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CN113234139A (zh) * 2020-04-17 2021-08-10 百奥赛图江苏基因生物技术有限公司 Tnfsf9基因人源化的非人动物及其构建方法和应用
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CN114984053B (zh) * 2022-06-24 2024-04-19 北京慧心医谷生物科技有限责任公司 一种用于治疗脊髓损伤的组合物及其制备方法和用途
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