MX2017015465A - Composicion farmaceutica o nutraceutica con resistencia contra la influencia del etanol. - Google Patents
Composicion farmaceutica o nutraceutica con resistencia contra la influencia del etanol.Info
- Publication number
- MX2017015465A MX2017015465A MX2017015465A MX2017015465A MX2017015465A MX 2017015465 A MX2017015465 A MX 2017015465A MX 2017015465 A MX2017015465 A MX 2017015465A MX 2017015465 A MX2017015465 A MX 2017015465A MX 2017015465 A MX2017015465 A MX 2017015465A
- Authority
- MX
- Mexico
- Prior art keywords
- weight
- core
- coating layer
- meth
- pharmaceutical
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 239000002417 nutraceutical Substances 0.000 title abstract 2
- 235000021436 nutraceutical agent Nutrition 0.000 title abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 title 2
- 239000011247 coating layer Substances 0.000 abstract 6
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 abstract 4
- 125000000129 anionic group Chemical group 0.000 abstract 3
- 239000000178 monomer Substances 0.000 abstract 3
- 229920000615 alginic acid Polymers 0.000 abstract 2
- 229960001126 alginic acid Drugs 0.000 abstract 2
- 235000010443 alginic acid Nutrition 0.000 abstract 2
- 239000000783 alginic acid Substances 0.000 abstract 2
- 150000004781 alginic acids Chemical class 0.000 abstract 2
- 229920001577 copolymer Polymers 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 229920003176 water-insoluble polymer Polymers 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/501—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Inorganic Chemistry (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- General Preparation And Processing Of Foods (AREA)
Abstract
La invención se refiere a una composición farmacéutica o nutracéutica, que comprende: un núcleo a) que comprende un ingrediente activo y un polímero insoluble en agua, una capa de revestimiento b) por encima del núcleo a) que comprende una sal de un ácido algínico, y una capa de revestimiento c) por encima de la capa de revestimiento b) que comprende un copolímero de (met)acrilato aniónico polimerizado de una mezcla de monómero de (met)acrilato que comprende el 5-75% en peso, con relación al peso total de la mezcla de monómero de (met)acrilato, de monómeros de (met)acrilato con un grupo aniónico, en donde la cantidad del polímero insoluble en agua en el núcleo a) es del 2 al 20% en peso con relación al peso del núcleo a) y la cantidad de la sal de un ácido algínico en la capa de revestimiento b) es del 5 al 85% en peso con relación al peso del núcleo a) y la cantidad del copolímero de (met)acrilato aniónico en la capa de revestimiento c) es del 10 al 75% en peso con relación al peso del núcleo a) y la capa de revestimiento b).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2843CH2015 | 2015-06-05 | ||
| PCT/EP2016/061551 WO2016193034A1 (en) | 2015-06-05 | 2016-05-23 | Pharmaceutical or nutraceutical composition with resistance against the influence of ethanol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2017015465A true MX2017015465A (es) | 2018-03-28 |
| MX376383B MX376383B (es) | 2025-03-07 |
Family
ID=56084021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017015465A MX376383B (es) | 2015-06-05 | 2016-05-23 | Composicion farmaceutica o nutraceutica con resistencia contra la influencia del etanol |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US10980751B2 (es) |
| EP (1) | EP3302444B1 (es) |
| JP (1) | JP6824197B2 (es) |
| KR (1) | KR20180015245A (es) |
| CN (1) | CN107708677B (es) |
| BR (1) | BR112017025148A2 (es) |
| CA (1) | CA2986188A1 (es) |
| ES (1) | ES2838816T3 (es) |
| HK (1) | HK1244699A1 (es) |
| HU (1) | HUE052340T2 (es) |
| IL (1) | IL255534A (es) |
| MX (1) | MX376383B (es) |
| PL (1) | PL3302444T3 (es) |
| SI (1) | SI3302444T1 (es) |
| WO (1) | WO2016193034A1 (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20200289423A1 (en) * | 2017-09-14 | 2020-09-17 | Evonik Operations Gmbh | Polymer and dosage form with sustained release properties and resistance against the influence of ethanol |
| US11806433B2 (en) * | 2017-11-01 | 2023-11-07 | Edgemont Pharmaceuticals, LLC Trust | Alcohol-resistant oral pharmaceutical compositions of lorazepam |
| KR20200130369A (ko) | 2018-03-09 | 2020-11-18 | 에보니크 오퍼레이션즈 게엠베하 | 에탄올의 영향에 대한 내성을 갖는 중합체 혼합물 |
| AU2019275406B2 (en) | 2018-05-24 | 2024-11-14 | Celanese Eva Performance Polymers Llc | Implantable device for sustained release of a macromolecular drug compound |
| SG11202005949UA (en) | 2018-05-24 | 2020-07-29 | Celanese Eva Performance Polymers Corp | Implantable device for sustained release of a macromolecular drug compound |
| WO2019222856A1 (en) | 2018-05-24 | 2019-11-28 | Nureva Inc. | Method, apparatus and computer-readable media to manage semi-constant (persistent) sound sources in microphone pickup/focus zones |
| EP3891191A1 (en) * | 2018-12-05 | 2021-10-13 | Evonik Operations GmbH | Process for preparing polymeric particles |
| US20220087940A1 (en) * | 2019-03-11 | 2022-03-24 | Evonik Operations Gmbh | Dosage form comprising a polymeric matrix |
| EP4176874A1 (en) * | 2021-11-09 | 2023-05-10 | Evonik Operations GmbH | Pharmaceutical or nutraceutical composition with an alcohol resistant single layer coating system |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2135073C3 (de) | 1971-07-14 | 1974-07-11 | Roehm Gmbh | Überzugsmittel für Arzneiformen |
| DE9414066U1 (de) | 1994-08-31 | 1994-11-03 | Röhm GmbH & Co. KG, 64293 Darmstadt | Überzugs- und Bindemittel für Arzneiformen sowie damit hergestellte Arzneiform |
| DE9414065U1 (de) | 1994-08-31 | 1994-11-03 | Röhm GmbH & Co. KG, 64293 Darmstadt | Thermoplastischer Kunststoff für darmsaftlösliche Arznei-Umhüllungen |
| DE10011447A1 (de) | 2000-03-10 | 2001-09-20 | Roehm Gmbh | Dispersion mit nichtionischem Emulgator |
| DE10013029A1 (de) | 2000-03-17 | 2001-09-20 | Roehm Gmbh | Mehrschichtige Arzneiform für die Colonfreigabe |
| CA2403670C (en) | 2001-01-31 | 2010-02-09 | Rohm Gmbh & Co. Kg | Multiparticulate drug form comprising at least two differently coated pellet forms |
| DE10214002A1 (de) | 2002-03-27 | 2003-10-09 | Roehm Gmbh | Pharmazeutische Formulierung für den Wirkstoff Budesonid |
| DE10250543A1 (de) | 2002-10-29 | 2004-05-19 | Röhm GmbH & Co. KG | Mehrschichtige Arzneiform |
| DE102004011349A1 (de) | 2004-03-05 | 2005-09-22 | Basf Ag | Wässrige Polymerdispersion auf Basis von Alkyl(meth)-acrylaten |
| TW200533391A (en) | 2004-03-25 | 2005-10-16 | Sun Pharmaceutical Ind Ltd | Gastric retention drug delivery system |
| DE102004035936A1 (de) | 2004-07-23 | 2006-03-16 | Röhm GmbH & Co. KG | Mehrschichtige Arzneiform |
| WO2006037766A1 (en) * | 2004-10-05 | 2006-04-13 | Altana Pharma Ag | Oral pharmaceutical preparation comprising a proton pump antagonist and a basic excipient |
| DE102005024614A1 (de) | 2005-05-25 | 2006-11-30 | Röhm Gmbh | Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug |
| PL116330U1 (en) * | 2005-10-31 | 2007-04-02 | Alza Corp | Method for the reduction of alcohol provoked rapid increase in the released dose of the orally administered opioide with prolonged liberation |
| US20070104789A1 (en) | 2005-11-04 | 2007-05-10 | Donald Spector | Gastro-resistant and ethanol-resistant controlled-release formulations comprising hydromorphone |
| DE102007009242A1 (de) | 2007-02-22 | 2008-09-18 | Evonik Röhm Gmbh | Pellets mit magensaftresistenter Wirkstoff-Matix |
| DE102007009243A1 (de) | 2007-02-22 | 2008-09-18 | Evonik Röhm Gmbh | Pellets mit einer Wirkstoff-Matrix und einem Polymerüberzug, sowie ein Verfahren zur Herstellung der Pellets |
| US9237760B2 (en) | 2008-01-10 | 2016-01-19 | Evonik Röhm Gmbh | Coated pharmaceutical or nutraceutical preparation with enhanced active substance release in the colon |
| SI2408436T1 (sl) | 2009-03-18 | 2017-06-30 | Evonik Roehm Gmbh | Farmacevtski sestavek z nadzorovanim sproščanjem z odpornostjo na vpliv etanola, ki uporablja oplaščenje, ki vsebuje nevtralne vinil polimere in ekscipiente |
| KR101873075B1 (ko) | 2010-08-18 | 2018-06-29 | 에보니크 룀 게엠베하 | 하나 이상의 알긴산 염을 포함하는 위 내성 제약 또는 건강기능식품 제제 |
| US10842752B2 (en) | 2012-08-27 | 2020-11-24 | Evonik Operations Gmbh | Pharmaceutical or nutraceutical composition with sustained release characteristic and with resistance against the influence of ethanol |
| AU2012388440B2 (en) | 2012-08-27 | 2017-08-31 | Evonik Operations Gmbh | Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol |
-
2016
- 2016-05-23 ES ES16725486T patent/ES2838816T3/es active Active
- 2016-05-23 JP JP2017563018A patent/JP6824197B2/ja not_active Expired - Fee Related
- 2016-05-23 SI SI201631025T patent/SI3302444T1/sl unknown
- 2016-05-23 EP EP16725486.1A patent/EP3302444B1/en active Active
- 2016-05-23 KR KR1020187000337A patent/KR20180015245A/ko not_active Withdrawn
- 2016-05-23 WO PCT/EP2016/061551 patent/WO2016193034A1/en active Application Filing
- 2016-05-23 BR BR112017025148-5A patent/BR112017025148A2/pt active Search and Examination
- 2016-05-23 CA CA2986188A patent/CA2986188A1/en active Pending
- 2016-05-23 HK HK18104272.1A patent/HK1244699A1/zh unknown
- 2016-05-23 US US15/578,746 patent/US10980751B2/en not_active Expired - Fee Related
- 2016-05-23 MX MX2017015465A patent/MX376383B/es active IP Right Grant
- 2016-05-23 HU HUE16725486A patent/HUE052340T2/hu unknown
- 2016-05-23 CN CN201680032716.7A patent/CN107708677B/zh not_active Expired - Fee Related
- 2016-05-23 PL PL16725486.1T patent/PL3302444T3/pl unknown
-
2017
- 2017-11-08 IL IL255534A patent/IL255534A/en unknown
-
2021
- 2021-03-16 US US17/203,403 patent/US20210205230A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PL3302444T3 (pl) | 2021-03-22 |
| US20180140556A1 (en) | 2018-05-24 |
| WO2016193034A1 (en) | 2016-12-08 |
| IL255534A (en) | 2018-01-31 |
| MX376383B (es) | 2025-03-07 |
| JP2018518478A (ja) | 2018-07-12 |
| JP6824197B2 (ja) | 2021-02-03 |
| BR112017025148A2 (pt) | 2018-08-07 |
| US10980751B2 (en) | 2021-04-20 |
| ES2838816T3 (es) | 2021-07-02 |
| HUE052340T2 (hu) | 2021-05-28 |
| US20210205230A1 (en) | 2021-07-08 |
| KR20180015245A (ko) | 2018-02-12 |
| EP3302444A1 (en) | 2018-04-11 |
| SI3302444T1 (sl) | 2021-01-29 |
| CN107708677B (zh) | 2021-07-13 |
| CA2986188A1 (en) | 2016-12-08 |
| HK1244699A1 (zh) | 2018-08-17 |
| CN107708677A (zh) | 2018-02-16 |
| EP3302444B1 (en) | 2020-09-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB | Transfer or rights |
Owner name: EVONIK OPERATIONS GMBH |
|
| HC | Change of company name or juridical status |
Owner name: EVONIK OPERATIONS GMBH Owner name: KONECRANES GLOBAL CORPORATION |
|
| FG | Grant or registration |