MX2016012055A - Ensayos de proteinas glicosiladas. - Google Patents
Ensayos de proteinas glicosiladas.Info
- Publication number
- MX2016012055A MX2016012055A MX2016012055A MX2016012055A MX2016012055A MX 2016012055 A MX2016012055 A MX 2016012055A MX 2016012055 A MX2016012055 A MX 2016012055A MX 2016012055 A MX2016012055 A MX 2016012055A MX 2016012055 A MX2016012055 A MX 2016012055A
- Authority
- MX
- Mexico
- Prior art keywords
- glycated
- protein
- glycated protein
- reagents
- detection
- Prior art date
Links
- 108091005996 glycated proteins Proteins 0.000 title abstract 4
- 238000002731 protein assay Methods 0.000 title 1
- 238000003556 assay Methods 0.000 abstract 3
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 206010018429 Glucose tolerance impaired Diseases 0.000 abstract 1
- 102000017011 Glycated Hemoglobin A Human genes 0.000 abstract 1
- 102000001554 Hemoglobins Human genes 0.000 abstract 1
- 108010054147 Hemoglobins Proteins 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 230000007274 generation of a signal involved in cell-cell signaling Effects 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 108091005995 glycated hemoglobin Proteins 0.000 abstract 1
- 108010004903 glycosylated serum albumin Proteins 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/41—Porphyrin- or corrin-ring-containing peptides
- A61K38/42—Haemoglobins; Myoglobins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
- G01N33/723—Glycosylated haemoglobin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
- G01N33/54387—Immunochromatographic test strips
- G01N33/54388—Immunochromatographic test strips based on lateral flow
- G01N33/54389—Immunochromatographic test strips based on lateral flow with bidirectional or multidirectional lateral flow, e.g. wherein the sample flows from a single, common sample application point into multiple strips, lanes or zones
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/76—Assays involving albumins other than in routine use for blocking surfaces or for anchoring haptens during immunisation
- G01N2333/765—Serum albumin, e.g. HSA
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Se describen métodos, dispositivos y reactivos para la realización de ensayos de la hemoglobina A1c, la albúmina glicosilada, y otras proteínas glicosiladas. Los métodos implican una relación determinada entre la proteína glicosilada y la proteína no glicosilada. En algunas aplicaciones, el ensayo utiliza LOCI para la generación de la señal. Esta invención se refiere a ensayos, dispositivos y reactivos correspondientes para la detección de la proteína glicosilada, particularmente incluyendo hemoglobina glicosilada. Como se entiende generalmente, tal detección es útil en la gestión de los niveles de glucosa en sangre en pacientes diabéticos y para supervisar el estado de los individuos pre diabéticos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461968297P | 2014-03-20 | 2014-03-20 | |
PCT/US2015/021865 WO2015143394A1 (en) | 2014-03-20 | 2015-03-20 | Glycated protein assay |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016012055A true MX2016012055A (es) | 2017-04-13 |
Family
ID=54145409
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016012055A MX2016012055A (es) | 2014-03-20 | 2015-03-20 | Ensayos de proteinas glicosiladas. |
Country Status (7)
Country | Link |
---|---|
US (1) | US10520515B2 (es) |
EP (2) | EP3404413B1 (es) |
KR (1) | KR20160134796A (es) |
CN (2) | CN109900908A (es) |
MX (1) | MX2016012055A (es) |
RU (1) | RU2698311C2 (es) |
WO (1) | WO2015143394A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3427054B1 (en) * | 2016-03-07 | 2025-01-08 | Quidel Cardiovascular Inc. | Immunoassay controls and the use thereof |
CN107656074A (zh) * | 2017-09-07 | 2018-02-02 | 基蛋生物科技股份有限公司 | 一种使用双色荧光免疫层析技术检测糖化血红蛋白的试剂盒 |
US20210311070A1 (en) * | 2018-07-11 | 2021-10-07 | Provigate Inc. | Healthcare management method |
JP2021531750A (ja) | 2018-07-12 | 2021-11-25 | ボード オブ リージェンツ, ザ ユニバーシティ オブ テキサス システムBoard Of Regents, The University Of Texas System | オリゴヌクレオチドによる分子近傍検出 |
ES2990182T3 (es) * | 2019-01-17 | 2024-11-29 | Hoffmann La Roche | Flujo de trabajo de muestras a alta velocidad para medición de HbA1c basada en CL-EM |
CN109726510B (zh) * | 2019-01-23 | 2022-12-23 | 山东大学 | 一种蛋白质糖化位点鉴定方法 |
US20200284807A1 (en) * | 2019-03-05 | 2020-09-10 | Victor Manneh | Saturation binding ratiometric assay |
US12195879B2 (en) * | 2019-07-26 | 2025-01-14 | Alliance For Sustainable Energy, Llc | Extreme large grain (1 mm) lateral growth of Cd(Se,Te) alloy thin films by reactive anneals |
CN113125749B (zh) * | 2021-03-30 | 2024-07-16 | 潍坊三维生物工程集团有限公司 | 一种用于检测血清糖化白蛋白的试剂盒 |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4269605A (en) | 1978-06-28 | 1981-05-26 | Amicon Corporation | Method and kit for separation of glycoproteins |
US4861728A (en) | 1987-07-24 | 1989-08-29 | Becton, Dickinson And Company | Immunoassay of glycosylated hemoglobin using a labeled boron reagent |
US5110745A (en) | 1989-06-01 | 1992-05-05 | The Trustees Of The University Of Pennsylvania | Methods of detecting glycated proteins |
EP0455225B1 (en) * | 1990-05-01 | 1995-03-29 | Nacalai Tesque, Inc. | Method for measuring the percentage of glycation of a particular protein |
GB9024771D0 (en) * | 1990-11-14 | 1991-01-02 | Axis Research | Assay |
US5284777A (en) | 1991-03-04 | 1994-02-08 | Isolab, Inc. | Combined glycated hemoglobin and immunoturbidometric glycated albumin assay from whole blood lysate |
GB9415143D0 (en) | 1994-07-27 | 1994-09-14 | Edwards Raymond | Glycated haemoglobin assay |
US6162645A (en) | 1997-03-13 | 2000-12-19 | Abbott Laboratories | Determination of % glycated hemoglobin |
ES2182530T3 (es) * | 1998-06-01 | 2003-03-01 | Roche Diagnostics Corp | Conjugados de complejos bipiridil-osmio de redox reversible. |
JP2002296281A (ja) * | 2001-03-07 | 2002-10-09 | F Hoffmann La Roche Ag | 改良された均一系イムノアッセイ法 |
US20050227370A1 (en) | 2004-03-08 | 2005-10-13 | Ramel Urs A | Body fluid analyte meter & cartridge system for performing combined general chemical and specific binding assays |
US7172906B2 (en) * | 2004-11-16 | 2007-02-06 | Dade Behring Inc. | Reduction of non-specific binding in assays |
AU2006245727B2 (en) | 2005-05-13 | 2009-07-16 | Shell Internationale Research Maatschappij B.V. | Removal of carbon dioxide from a gas stream |
WO2007010950A1 (ja) | 2005-07-19 | 2007-01-25 | Kikkoman Corporation | 糖化蛋白質の測定方法および測定キット |
JP4834771B2 (ja) | 2006-07-21 | 2011-12-14 | エフ.ホフマン−ラ ロシュ アーゲー | ヘモグロビン消化用試薬 |
US8377379B2 (en) | 2006-12-15 | 2013-02-19 | Kimberly-Clark Worldwide, Inc. | Lateral flow assay device |
JP2011525800A (ja) | 2008-06-27 | 2011-09-29 | ノボ ノルディスク ヘルス ケア アーゲー | 長時間にわたる循環半減期を有するn−グリコシル化ヒト成長ホルモン |
US20110269147A1 (en) | 2008-07-18 | 2011-11-03 | Bayer Healthcare Llc | Methods, Devices, and Systems for Glycated Hemoglobin Analysis |
WO2009099269A1 (en) * | 2008-10-24 | 2009-08-13 | Boditechmed Inc. | System for the quantitative measurement of glycohemoglobin and a method for measuring the content of glycohemoglobin using the same |
US20120149128A1 (en) * | 2009-02-23 | 2012-06-14 | Victor Manneh | Assays and assay devices |
AU2010249486B2 (en) | 2009-05-20 | 2016-02-25 | Relia Biotechnologies (Shenzhen) Ltd. | Systems and methods for determining the percentage of glycated hemoglobin |
US8603828B2 (en) | 2009-11-18 | 2013-12-10 | Bio-Rad Laboratories, Inc. | Multiplex immunoassays for hemoglobin, hemoglobin variants, and glycated forms |
CN103163297A (zh) * | 2011-12-16 | 2013-06-19 | 王哲 | 多功能荧光免疫层析快速定量检测卡 |
CA2804843C (en) | 2012-02-06 | 2021-02-02 | Ortho-Clinical Diagnostics, Inc. | Multiple time windows for extending the range of an assay |
EP2657681A1 (en) | 2012-04-26 | 2013-10-30 | Roche Diagnostics GmbH | Improvement of the sensitivity and the dynamic range of photometric assays by generating multiple calibration curves |
CN102998463A (zh) | 2012-11-29 | 2013-03-27 | 英科新创(厦门)科技有限公司 | 一种测量糖化血红蛋白的方法及试剂盒 |
-
2015
- 2015-03-20 RU RU2016141232A patent/RU2698311C2/ru not_active IP Right Cessation
- 2015-03-20 EP EP18181951.7A patent/EP3404413B1/en active Active
- 2015-03-20 KR KR1020167028970A patent/KR20160134796A/ko not_active Withdrawn
- 2015-03-20 EP EP15765809.7A patent/EP3120147B1/en active Active
- 2015-03-20 WO PCT/US2015/021865 patent/WO2015143394A1/en active Application Filing
- 2015-03-20 US US15/127,706 patent/US10520515B2/en active Active - Reinstated
- 2015-03-20 CN CN201910135062.6A patent/CN109900908A/zh active Pending
- 2015-03-20 MX MX2016012055A patent/MX2016012055A/es unknown
- 2015-03-20 CN CN201580026471.2A patent/CN106461670B/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US10520515B2 (en) | 2019-12-31 |
EP3120147B1 (en) | 2018-09-19 |
EP3404413B1 (en) | 2020-01-01 |
WO2015143394A1 (en) | 2015-09-24 |
KR20160134796A (ko) | 2016-11-23 |
CN106461670B (zh) | 2019-03-01 |
RU2016141232A (ru) | 2018-04-20 |
RU2698311C2 (ru) | 2019-08-26 |
CN106461670A (zh) | 2017-02-22 |
EP3120147A1 (en) | 2017-01-25 |
CN109900908A (zh) | 2019-06-18 |
EP3120147A4 (en) | 2017-08-16 |
EP3404413A1 (en) | 2018-11-21 |
US20170176463A1 (en) | 2017-06-22 |
RU2016141232A3 (es) | 2018-11-02 |
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