MX2015016130A - Tabletas ingeribles de n-acetilcisteina. - Google Patents
Tabletas ingeribles de n-acetilcisteina.Info
- Publication number
- MX2015016130A MX2015016130A MX2015016130A MX2015016130A MX2015016130A MX 2015016130 A MX2015016130 A MX 2015016130A MX 2015016130 A MX2015016130 A MX 2015016130A MX 2015016130 A MX2015016130 A MX 2015016130A MX 2015016130 A MX2015016130 A MX 2015016130A
- Authority
- MX
- Mexico
- Prior art keywords
- tablets
- swallowable
- acetylcysteine
- acetylcysteine tablets
- nac
- Prior art date
Links
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 title abstract 3
- 229960004308 acetylcysteine Drugs 0.000 title abstract 3
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000006835 compression Effects 0.000 abstract 1
- 238000007906 compression Methods 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/12—Mucolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Esta invención se refiere a tabletas ingeribles que contienen al menos 80% en peso de N-acetilcisteina (NAC) y al menos un excipiente farmacéuticamente aceptable, en particular tabletas en las cuales se elimina el olor a azufre, caracterizada porque las tabletas se forman usando un granulado preparado por medio de un proceso de granulación seca de únicamente el ingrediente activo, con el cual los excipientes se mezclan antes de la compresión.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000874A ITMI20130874A1 (it) | 2013-05-29 | 2013-05-29 | Compresse deglutibili di n-acetilcisteina |
| PCT/EP2014/060950 WO2014191410A1 (en) | 2013-05-29 | 2014-05-27 | Swallowable n-acetylcysteine tablets |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015016130A true MX2015016130A (es) | 2016-08-08 |
| MX366917B MX366917B (es) | 2019-07-30 |
Family
ID=48748383
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015016130A MX366917B (es) | 2013-05-29 | 2014-05-27 | Tabletas ingeribles de n-acetilcisteina. |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US9808427B2 (es) |
| EP (1) | EP3003278B1 (es) |
| JP (1) | JP6438013B2 (es) |
| CN (1) | CN105228595B (es) |
| AU (1) | AU2014273148B2 (es) |
| BR (1) | BR112015029038B1 (es) |
| CA (1) | CA2911474C (es) |
| CY (1) | CY1122114T1 (es) |
| DK (1) | DK3003278T3 (es) |
| EA (1) | EA031856B1 (es) |
| ES (1) | ES2721649T3 (es) |
| HR (1) | HRP20190687T1 (es) |
| HU (1) | HUE044880T2 (es) |
| IL (1) | IL242439B (es) |
| IT (1) | ITMI20130874A1 (es) |
| LT (1) | LT3003278T (es) |
| MX (1) | MX366917B (es) |
| MY (1) | MY174005A (es) |
| PE (1) | PE20160184A1 (es) |
| PH (1) | PH12015502608A1 (es) |
| PL (1) | PL3003278T3 (es) |
| PT (1) | PT3003278T (es) |
| RS (1) | RS58653B1 (es) |
| SG (2) | SG10201709861YA (es) |
| SI (1) | SI3003278T1 (es) |
| SM (1) | SMT201900234T1 (es) |
| TR (1) | TR201906101T4 (es) |
| UA (1) | UA117829C2 (es) |
| WO (1) | WO2014191410A1 (es) |
| ZA (1) | ZA201508411B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SMT202300148T1 (it) * | 2016-12-15 | 2023-07-20 | Zambon Spa | N-acetilcisteina per uso come agente antibatterico |
| IT201700109080A1 (it) * | 2017-09-28 | 2019-03-28 | Neilos S R L | Composizione per la prevenzione e/o il trattamento delle affezioni delle vie respiratorie |
| MX2020004403A (es) * | 2017-11-02 | 2020-08-06 | Zambon Spa | Composiciones farmaceuticas que comprenden safinamida. |
| US10288629B1 (en) * | 2017-12-19 | 2019-05-14 | Aeterna Zentaris, Inc. | Method of assessing growth hormone deficiency in humans by a macimorelin containing composition |
| KR20210003786A (ko) * | 2018-06-14 | 2021-01-12 | 폭셀 | 당뇨병의 치료에서 사용하기 위한 트리아진 유도체를 포함하는 필름 코팅정 |
| IT201800007928A1 (it) * | 2018-08-07 | 2020-02-07 | Sofar Spa | Composizione contenente un agente mucolitico per il trattamento di ipersecrezione di muco e dispositivo per il suo dosaggio |
| CN113645968A (zh) * | 2019-03-18 | 2021-11-12 | 西达赛奈医疗中心 | 治疗胃肠疾病和障碍的组合物和方法 |
| CN112843008A (zh) * | 2021-02-07 | 2021-05-28 | 广东赛康制药厂有限公司 | 一种乙酰半胱氨酸片及其制备方法 |
| CN114886860B (zh) * | 2022-06-28 | 2023-04-25 | 山东达因海洋生物制药股份有限公司 | 一种乙酰半胱氨酸药物组合物及其制剂和制备工艺 |
| CN119792224A (zh) * | 2025-01-21 | 2025-04-11 | 江苏安必生制药有限公司 | 一种乙酰半胱氨酸泡腾片及其制备工艺 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE125702T1 (de) * | 1990-10-19 | 1995-08-15 | Spirig Ag | Feste, schnell-lösliche arzneimittelzubereitung enthaltend s-(carboxymethyl)-l-cystein und/oder n-acetylcystein. |
| GB9305058D0 (en) * | 1993-03-12 | 1993-04-28 | Penn Pharm Ltd | Pharmaceutical compositions |
| IT1311907B1 (it) * | 1999-04-06 | 2002-03-20 | Zambon Spa | Compresse deglutibili ad alto contenuto di n-acetilcisteina. |
| US6623754B2 (en) * | 2001-05-21 | 2003-09-23 | Noveon Ip Holdings Corp. | Dosage form of N-acetyl cysteine |
| JP2003155232A (ja) * | 2001-09-07 | 2003-05-27 | Takeda Chem Ind Ltd | 不快な臭いが低減されたｌ−システイン配合固形製剤およびその製造方法 |
| US20080139654A1 (en) * | 2006-12-09 | 2008-06-12 | Eric Mott Soderling | Acetaminophen compositions having minimized side effects including reduced hepatotoxicity |
| IT1399492B1 (it) * | 2010-04-13 | 2013-04-19 | Alpex Pharma Sa | Composizioni farmaceutiche effervescenti contenenti n-acetilcisteina. |
| EP2574333B1 (en) * | 2011-09-27 | 2017-01-11 | Friulchem SpA | N-acetylcysteine effervescent tablet and its therapeutical applications |
-
2013
- 2013-05-29 IT IT000874A patent/ITMI20130874A1/it unknown
-
2014
- 2014-05-27 US US14/893,100 patent/US9808427B2/en active Active
- 2014-05-27 CA CA2911474A patent/CA2911474C/en active Active
- 2014-05-27 MY MYPI2015704193A patent/MY174005A/en unknown
- 2014-05-27 PE PE2015002421A patent/PE20160184A1/es active IP Right Grant
- 2014-05-27 DK DK14728495.4T patent/DK3003278T3/da active
- 2014-05-27 RS RS20190507A patent/RS58653B1/sr unknown
- 2014-05-27 UA UAA201512351A patent/UA117829C2/uk unknown
- 2014-05-27 SG SG10201709861YA patent/SG10201709861YA/en unknown
- 2014-05-27 ES ES14728495T patent/ES2721649T3/es active Active
- 2014-05-27 SG SG11201509177VA patent/SG11201509177VA/en unknown
- 2014-05-27 CN CN201480029563.1A patent/CN105228595B/zh active Active
- 2014-05-27 HU HUE14728495 patent/HUE044880T2/hu unknown
- 2014-05-27 WO PCT/EP2014/060950 patent/WO2014191410A1/en active Application Filing
- 2014-05-27 PT PT14728495T patent/PT3003278T/pt unknown
- 2014-05-27 BR BR112015029038-8A patent/BR112015029038B1/pt active IP Right Grant
- 2014-05-27 SM SM20190234T patent/SMT201900234T1/it unknown
- 2014-05-27 PL PL14728495T patent/PL3003278T3/pl unknown
- 2014-05-27 AU AU2014273148A patent/AU2014273148B2/en active Active
- 2014-05-27 HR HRP20190687TT patent/HRP20190687T1/hr unknown
- 2014-05-27 MX MX2015016130A patent/MX366917B/es active IP Right Grant
- 2014-05-27 JP JP2016516129A patent/JP6438013B2/ja active Active
- 2014-05-27 TR TR2019/06101T patent/TR201906101T4/tr unknown
- 2014-05-27 SI SI201431172T patent/SI3003278T1/sl unknown
- 2014-05-27 EA EA201592172A patent/EA031856B1/ru unknown
- 2014-05-27 LT LTEP14728495.4T patent/LT3003278T/lt unknown
- 2014-05-27 EP EP14728495.4A patent/EP3003278B1/en active Active
-
2015
- 2015-11-04 IL IL242439A patent/IL242439B/en active IP Right Grant
- 2015-11-13 ZA ZA2015/08411A patent/ZA201508411B/en unknown
- 2015-11-23 PH PH12015502608A patent/PH12015502608A1/en unknown
-
2019
- 2019-04-11 CY CY20191100404T patent/CY1122114T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |