MX2013004873A - Metodos y composiciones para tratar diarrea asociada con vih. - Google Patents
Metodos y composiciones para tratar diarrea asociada con vih.Info
- Publication number
- MX2013004873A MX2013004873A MX2013004873A MX2013004873A MX2013004873A MX 2013004873 A MX2013004873 A MX 2013004873A MX 2013004873 A MX2013004873 A MX 2013004873A MX 2013004873 A MX2013004873 A MX 2013004873A MX 2013004873 A MX2013004873 A MX 2013004873A
- Authority
- MX
- Mexico
- Prior art keywords
- diarrhea
- methods
- compositions
- treating hiv
- associated diarrhea
- Prior art date
Links
- 206010012735 Diarrhoea Diseases 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 229920001393 Crofelemer Polymers 0.000 abstract 1
- 206010000059 abdominal discomfort Diseases 0.000 abstract 1
- 229940047615 crofelemer Drugs 0.000 abstract 1
- ADNPLDHMAVUMIW-CUZNLEPHSA-N substance P Chemical group C([C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CCCN=C(N)N)C1=CC=CC=C1 ADNPLDHMAVUMIW-CUZNLEPHSA-N 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Se plantean en la presente métodos para tratar diarrea al administrar a un paciente en necesidad del mismo, un inhibidor de transporte de iones de cloruro en una cantidad suficiente para tratar diarrea. El tratamiento de diarrea incluye el tratamiento de diarrea así como el dolor, molestia abdominal y otros síntomas asociados con diarrea. En una modalidad, el inhibidor de transporte de iones de cloruro es crofelemer.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40862210P | 2010-10-31 | 2010-10-31 | |
| US40933510P | 2010-11-02 | 2010-11-02 | |
| US41624910P | 2010-11-22 | 2010-11-22 | |
| US201161434379P | 2011-01-19 | 2011-01-19 | |
| PCT/US2011/058549 WO2012058664A1 (en) | 2010-10-31 | 2011-10-31 | Methods and compositions for treating hiv-associated diarrhea |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013004873A true MX2013004873A (es) | 2013-08-21 |
| MX348184B MX348184B (es) | 2017-06-02 |
Family
ID=45994461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013004873A MX348184B (es) | 2010-10-31 | 2011-10-31 | Métodos y composiciones para tratar diarrea asociada con vih. |
Country Status (20)
| Country | Link |
|---|---|
| US (4) | US8962680B2 (es) |
| EP (1) | EP2632550B1 (es) |
| JP (2) | JP6063385B2 (es) |
| CN (2) | CN103370101A (es) |
| AU (1) | AU2011320155B2 (es) |
| BR (1) | BR112013010774A2 (es) |
| CA (1) | CA2816416C (es) |
| DK (1) | DK2632550T3 (es) |
| EC (1) | ECSP13012650A (es) |
| ES (1) | ES2635435T3 (es) |
| HK (1) | HK1249036A1 (es) |
| HU (1) | HUE035393T2 (es) |
| MX (1) | MX348184B (es) |
| PE (1) | PE20140036A1 (es) |
| PH (1) | PH12013500857A1 (es) |
| PL (1) | PL2632550T3 (es) |
| PT (1) | PT2632550T (es) |
| RU (1) | RU2597746C2 (es) |
| WO (1) | WO2012058664A1 (es) |
| ZA (1) | ZA201303136B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007248182B2 (en) | 2006-05-01 | 2013-05-23 | Napo Pharmaceuticals, Inc. | Method for treatment of constipation-predominant irritable bowel syndrome |
| US20070254050A1 (en) | 2006-05-01 | 2007-11-01 | Quart Barry D | Method for treatment of diarrhea-predominant irritable bowel syndrome |
| EP2529626B1 (en) * | 2006-05-01 | 2017-11-22 | Napo Pharmaceuticals, Inc. | Compositions and methods for treating or preventing colon cancer |
| JP6063385B2 (ja) | 2010-10-31 | 2017-01-18 | ナポ ファーマシューティカルズ インコーポレイテッド | Ｈｉｖ関連の下痢を治療するための方法および組成物 |
| US20140163096A1 (en) * | 2012-12-07 | 2014-06-12 | Pam Golden | Methods and compositions for treating hiv-associated diarrhea |
| US11389424B2 (en) | 2017-03-09 | 2022-07-19 | Napo Pharmaceuticals, Inc. | Methods and compositions for treating chemotherapy-induced diarrhea |
| JOP20190275A1 (ar) | 2017-05-31 | 2019-11-27 | Napo Pharmaceuticals Inc | طرق وتركيبات لعلاج اضطراب إسهال خِلقي |
| JOP20190276A1 (ar) | 2017-05-31 | 2019-11-27 | Napo Pharmaceuticals Inc | طرق وتركيبات لعلاج إسهال الحمض الصفراوي، والإسهال المرتبط باستئصال الأمعاء الدقيقة أو إزالة المرارة، ومتلازمة الأمعاء القصيرة |
| CA3128973A1 (en) | 2019-03-04 | 2020-09-10 | Bhaskar Bhattacharyya | Data compression and communication using machine learning |
| WO2021257089A1 (en) * | 2020-06-19 | 2021-12-23 | Napo Pharmaceuticals, Inc. | Methods and compositions for treating chemotherapy-induced diarrhea |
| WO2022115481A1 (en) * | 2020-11-24 | 2022-06-02 | Napo Pharmaceuticals, Inc. | Methods and compositions for treating post-acute infection gastrointestinal disorders |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5211944A (en) | 1990-10-12 | 1993-05-18 | Shaman Pharmaceuticals, Inc. | Proanthocyanidin polymers having antiviral activity and methods of obtaining same |
| KR100467532B1 (ko) | 1996-10-16 | 2005-01-24 | 피에스 팔마큐티칼스 인코퍼레이션 | 프로안토시아니딘 중합체로 된 항-설사 장용피 조제물 |
| WO2000047062A2 (en) | 1999-02-01 | 2000-08-17 | Shaman Pharmaceuticals, Inc. | Enteric formulations of proanthocyanidin polymer dietary supplements and methods for preparing same |
| US20040071793A1 (en) | 2002-10-05 | 2004-04-15 | Bobrowski Paul J. | Oral rehydration methods and compositions |
| WO2005074575A2 (en) | 2004-01-30 | 2005-08-18 | Microbia, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| CA2667449A1 (en) * | 2005-06-22 | 2007-01-04 | University Of Massachusetts | Hiv-1 protease inhibitors, and methods of making and using them |
| EP1962829A1 (en) | 2005-12-15 | 2008-09-03 | Bayer HealthCare AG | Diaryl ureas for treating virus infections |
| US20070254050A1 (en) * | 2006-05-01 | 2007-11-01 | Quart Barry D | Method for treatment of diarrhea-predominant irritable bowel syndrome |
| AU2007248182B2 (en) | 2006-05-01 | 2013-05-23 | Napo Pharmaceuticals, Inc. | Method for treatment of constipation-predominant irritable bowel syndrome |
| EP2529626B1 (en) | 2006-05-01 | 2017-11-22 | Napo Pharmaceuticals, Inc. | Compositions and methods for treating or preventing colon cancer |
| WO2010021681A2 (en) | 2008-08-18 | 2010-02-25 | Combinatorx (Singapore) Pte. Ltd. | Compositions and methods for treatment of viral diseases |
| US7928115B2 (en) | 2008-10-02 | 2011-04-19 | Salix Pharmaceuticals, Ltd. | Methods of treating travelers diarrhea and hepatic encephalopathy |
| PH12012500557A1 (en) | 2009-08-26 | 2012-10-22 | Glenmark Pharmaceuticals Ltd | Method for producing proanthocyanidin polymer compositions for pharmaceutical formulations |
| CA2777214A1 (en) * | 2009-10-06 | 2011-04-14 | The Regents Of The University Of California | Methods of treating diseases with proanthocyanidin oligomers such as crofelemer |
| US20110087530A1 (en) | 2009-10-09 | 2011-04-14 | Visa U.S.A. Inc. | Systems and Methods to Provide Loyalty Programs |
| JP6063385B2 (ja) | 2010-10-31 | 2017-01-18 | ナポ ファーマシューティカルズ インコーポレイテッド | Ｈｉｖ関連の下痢を治療するための方法および組成物 |
| BR112013018688B1 (pt) | 2011-01-27 | 2021-08-24 | Napo Pharmaceuticals, Inc | Método de produção de uma composição polimérica de proantocianidina |
| BR112014015314A2 (pt) | 2011-12-22 | 2017-06-13 | Glenmark Pharmaceuticals Ltd | composição farmacêutica não entérica compreendendo crofelemer |
| US20140163096A1 (en) | 2012-12-07 | 2014-06-12 | Pam Golden | Methods and compositions for treating hiv-associated diarrhea |
-
2011
- 2011-10-31 JP JP2013536904A patent/JP6063385B2/ja active Active
- 2011-10-31 MX MX2013004873A patent/MX348184B/es active IP Right Grant
- 2011-10-31 ES ES11837249.9T patent/ES2635435T3/es active Active
- 2011-10-31 PE PE2013000926A patent/PE20140036A1/es not_active Application Discontinuation
- 2011-10-31 PH PH1/2013/500857A patent/PH12013500857A1/en unknown
- 2011-10-31 BR BR112013010774A patent/BR112013010774A2/pt not_active Application Discontinuation
- 2011-10-31 CA CA2816416A patent/CA2816416C/en active Active
- 2011-10-31 US US13/285,397 patent/US8962680B2/en active Active
- 2011-10-31 PT PT118372499T patent/PT2632550T/pt unknown
- 2011-10-31 WO PCT/US2011/058549 patent/WO2012058664A1/en active Application Filing
- 2011-10-31 DK DK11837249.9T patent/DK2632550T3/en active
- 2011-10-31 RU RU2013123794/15A patent/RU2597746C2/ru active
- 2011-10-31 CN CN2011800637391A patent/CN103370101A/zh active Pending
- 2011-10-31 EP EP11837249.9A patent/EP2632550B1/en active Active
- 2011-10-31 HU HUE11837249A patent/HUE035393T2/en unknown
- 2011-10-31 CN CN201711077144.7A patent/CN107595836A/zh active Pending
- 2011-10-31 PL PL11837249T patent/PL2632550T3/pl unknown
- 2011-10-31 AU AU2011320155A patent/AU2011320155B2/en active Active
- 2011-11-11 US US13/294,307 patent/US20120107370A1/en not_active Abandoned
-
2013
- 2013-04-29 ZA ZA2013/03136A patent/ZA201303136B/en unknown
- 2013-05-31 EC ECSP13012650 patent/ECSP13012650A/es unknown
-
2014
- 2014-06-17 US US14/307,175 patent/US20140294903A1/en not_active Abandoned
-
2015
- 2015-01-15 US US14/597,740 patent/US9585868B2/en active Active
-
2016
- 2016-08-02 JP JP2016151656A patent/JP6310971B2/ja active Active
-
2018
- 2018-07-09 HK HK18108819.2A patent/HK1249036A1/zh unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB | Transfer or rights |
Owner name: NAPO PHARMACEUTICALS, INC. |
|
| FG | Grant or registration |