[go: up one dir, main page]

MX2010004397A - Celula para uso en la produccion de proteina exogena y proceso de produccion que utiliza la celula. - Google Patents

Celula para uso en la produccion de proteina exogena y proceso de produccion que utiliza la celula.

Info

Publication number
MX2010004397A
MX2010004397A MX2010004397A MX2010004397A MX2010004397A MX 2010004397 A MX2010004397 A MX 2010004397A MX 2010004397 A MX2010004397 A MX 2010004397A MX 2010004397 A MX2010004397 A MX 2010004397A MX 2010004397 A MX2010004397 A MX 2010004397A
Authority
MX
Mexico
Prior art keywords
cell
production
exogenous protein
producing
production process
Prior art date
Application number
MX2010004397A
Other languages
English (en)
Inventor
Hisahiro Tabuchi
Tomoya Sugiyama
Satoshi Tainaka
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of MX2010004397A publication Critical patent/MX2010004397A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/303—Liver or Pancreas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Se describe un proceso para producir una proteína de manera eficiente. En particular, se describe un proceso para producir un polipéptido, que comprende cultivar una célula capaz de expresar un transportador de bicarbonato en un nivel alto y tenga un ADN que codifique el polipéptido deseado introducido en el mismo, con lo que se produce el polipéptido deseado.
MX2010004397A 2007-10-24 2008-10-23 Celula para uso en la produccion de proteina exogena y proceso de produccion que utiliza la celula. MX2010004397A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007276182 2007-10-24
PCT/JP2008/069184 WO2009054433A1 (ja) 2007-10-24 2008-10-23 異種タンパク質製造のための細胞及びそれを用いた製造方法

Publications (1)

Publication Number Publication Date
MX2010004397A true MX2010004397A (es) 2010-06-01

Family

ID=40579535

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010004397A MX2010004397A (es) 2007-10-24 2008-10-23 Celula para uso en la produccion de proteina exogena y proceso de produccion que utiliza la celula.

Country Status (14)

Country Link
US (1) US9068212B2 (es)
EP (1) EP2213746B1 (es)
JP (1) JP5337044B2 (es)
KR (1) KR101636086B1 (es)
CN (1) CN101821403B (es)
AU (1) AU2008314973C1 (es)
BR (1) BRPI0818764B1 (es)
CA (1) CA2703493C (es)
DK (1) DK2213746T3 (es)
ES (1) ES2548294T3 (es)
MX (1) MX2010004397A (es)
RU (1) RU2494148C2 (es)
TW (1) TWI434935B (es)
WO (1) WO2009054433A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2011880B1 (en) 2006-04-13 2012-10-24 Chugai Seiyaku Kabushiki Kaisha Taurine transporter gene
JP5635260B2 (ja) 2007-03-15 2014-12-03 中外製薬株式会社 ポリペプチドの製造方法
MX2010001319A (es) 2007-08-07 2010-06-01 Chugai Pharmaceutical Co Ltd Metodo para producir proteinas heterogeneas.
JP5337043B2 (ja) 2007-10-15 2013-11-06 中外製薬株式会社 異種タンパク質を高生産する細胞の作製方法
ES2548294T3 (es) 2007-10-24 2015-10-15 Chugai Seiyaku Kabushiki Kaisha Célula para su uso en la producción de proteína exógena, y procedimiento de producción usando la célula
US8741601B2 (en) 2009-04-22 2014-06-03 Chugai Seiyaku Kabushiki Kaisha Method for producing a cell capable of high-yield production of heteroproteins
CN103492551A (zh) 2011-02-28 2014-01-01 诺维信股份有限公司 用于生产c4-二羧酸的微生物
EP2695947B1 (en) 2011-04-01 2017-03-01 Chugai Seiyaku Kabushiki Kaisha Recombinant polypeptide production method
WO2014055366A1 (en) * 2012-10-05 2014-04-10 Lamplight Farms Incorporated Outdoor appliance with retractable platform
EP2921554B1 (en) * 2012-10-10 2019-12-04 Chugai Seiyaku Kabushiki Kaisha Method for establishing modified host cell
EP3180422B2 (en) 2014-08-11 2021-11-17 F. Hoffmann-La Roche AG Method for increasing the specific production rate of eukaryotic cells
CN107287178B (zh) * 2016-04-12 2019-10-29 中国科学院微生物研究所 Csad蛋白及其编码基因在抗流感病毒中的应用
CN113242907B (zh) * 2018-12-11 2025-01-07 富士胶片株式会社 动物细胞、动物细胞的制造方法及靶蛋白的制造方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59184841A (ja) * 1983-04-05 1984-10-20 ベクトン・デイツキンソン・アンド・カンパニ− サンプル中の白血球のサブクラスを識別する方法および装置
GB9019812D0 (en) * 1990-09-11 1990-10-24 Scotgen Ltd Novel antibodies for treatment and prevention of infection in animals and man
US6225115B1 (en) * 1992-03-04 2001-05-01 Synaptic Pharmaceutical Corporation DNA encoding taurine and GABA transporters and uses thereof
US5658786A (en) * 1992-03-04 1997-08-19 Synaptic Pharmaceutical Corporation DNA encoding rat taurine transporter and uses thereof
TW402639B (en) 1992-12-03 2000-08-21 Transkaryotic Therapies Inc Protein production and protein delivery
JP3630453B2 (ja) 1994-09-30 2005-03-16 中外製薬株式会社 Ｉｌ−６レセプター抗体を有効成分とする未熟型骨髄腫細胞治療剤
AU695117B2 (en) 1994-10-06 1998-08-06 Hoechst Aktiengesellschaft Regulated genes by stimulation of chondrocytes with IL-1beta
JPH09203734A (ja) * 1996-01-26 1997-08-05 Sumitomo Electric Ind Ltd 抗血清、抗体、リガンド及びそれらの検出方法
JPH1075787A (ja) 1996-09-02 1998-03-24 Asahi Chem Ind Co Ltd 変異型アラニンアミノトランスフェラーゼおよびその製造法
JPH10191984A (ja) 1997-01-09 1998-07-28 Oriental Yeast Co Ltd 活性型ヒトａｌｔの製造法
DE19855313A1 (de) * 1998-12-01 2000-06-08 Degussa Verfahren zur fermentativen Herstellung von D-Pantothensäure durch Verstärkung des panD-Gens in Mikroorganismen
DE60034954D1 (de) * 1999-09-14 2007-07-05 Xenoport Inc Substrate und screeningverfahren für transportproteine
US6812339B1 (en) * 2000-09-08 2004-11-02 Applera Corporation Polymorphisms in known genes associated with human disease, methods of detection and uses thereof
WO2002092768A2 (en) 2001-05-14 2002-11-21 University Of Maryland, Baltimore Novel alanine transaminase enzyme and methods of use
ATE556591T1 (de) 2001-11-08 2012-05-15 Abbott Biotherapeutics Corp Stabile pharmazeutische flüssigformulierung von igg-antikörpern
WO2003062173A2 (en) * 2002-01-18 2003-07-31 Cargill, Incorporated Alanine 2,3- aminomutase
US20050265983A1 (en) * 2002-11-17 2005-12-01 Eldad Melamed Methods, nucleic acid constructs and cells for treating neurodegenerative disorders
IL152905A0 (en) 2002-11-17 2003-06-24 Univ Ramot Dopaminergic markers induction in neuronal-like cells isolated from adult human bone marrow stromal cells: implications for novel gene therapy strategy for parkinsons disease
US20030165495A1 (en) * 2003-04-01 2003-09-04 Carulli John P. Nucleic acids and polypeptides
US20050170391A1 (en) 2004-01-30 2005-08-04 Xenoport, Inc. TAUT1 transporters expressed in blood brain barrier cells
KR100789645B1 (ko) * 2004-04-14 2007-12-27 주식회사유한양행 Ｂ형 간염바이러스의 ｓ-표면항원을 인식하는 인간화 항체및 이의 제조방법
EP2216046B1 (en) * 2004-07-09 2014-03-12 Chugai Seiyaku Kabushiki Kaisha Anti-glypican 3 antibody
CA2522152A1 (en) * 2004-10-07 2006-04-07 Kabushiki Kaisha Sangi Transdermal and transmucosal preparations
PA8672101A1 (es) 2005-04-29 2006-12-07 Centocor Inc Anticuerpos anti-il-6, composiciones, métodos y usos
WO2007056507A1 (en) * 2005-11-09 2007-05-18 Abbott Laboratories Human bnp immunospecific antibodies
WO2007076115A2 (en) * 2005-12-23 2007-07-05 Arcadia Biosciences, Inc. Nitrogen-efficient monocot plants
EP2011880B1 (en) * 2006-04-13 2012-10-24 Chugai Seiyaku Kabushiki Kaisha Taurine transporter gene
JP5635260B2 (ja) 2007-03-15 2014-12-03 中外製薬株式会社 ポリペプチドの製造方法
MX2010001319A (es) * 2007-08-07 2010-06-01 Chugai Pharmaceutical Co Ltd Metodo para producir proteinas heterogeneas.
JP5337043B2 (ja) 2007-10-15 2013-11-06 中外製薬株式会社 異種タンパク質を高生産する細胞の作製方法
ES2548294T3 (es) 2007-10-24 2015-10-15 Chugai Seiyaku Kabushiki Kaisha Célula para su uso en la producción de proteína exógena, y procedimiento de producción usando la célula
US8741601B2 (en) * 2009-04-22 2014-06-03 Chugai Seiyaku Kabushiki Kaisha Method for producing a cell capable of high-yield production of heteroproteins

Also Published As

Publication number Publication date
ES2548294T3 (es) 2015-10-15
RU2010120677A (ru) 2011-11-27
EP2213746B1 (en) 2015-07-15
HK1143404A1 (en) 2010-12-31
TWI434935B (zh) 2014-04-21
CN101821403A (zh) 2010-09-01
DK2213746T3 (en) 2015-08-03
KR101636086B1 (ko) 2016-07-04
JP5337044B2 (ja) 2013-11-06
CN101821403B (zh) 2014-01-01
EP2213746A1 (en) 2010-08-04
CA2703493C (en) 2016-11-08
BRPI0818764A2 (pt) 2015-04-22
US20110014654A1 (en) 2011-01-20
RU2494148C2 (ru) 2013-09-27
WO2009054433A1 (ja) 2009-04-30
JPWO2009054433A1 (ja) 2011-03-03
BRPI0818764B1 (pt) 2017-11-21
TW200934870A (en) 2009-08-16
CA2703493A1 (en) 2009-04-30
US9068212B2 (en) 2015-06-30
EP2213746A4 (en) 2010-11-24
KR20100082003A (ko) 2010-07-15
AU2008314973A1 (en) 2009-04-30
AU2008314973C1 (en) 2014-05-08
AU2008314973B2 (en) 2014-01-09

Similar Documents

Publication Publication Date Title
MX2010004397A (es) Celula para uso en la produccion de proteina exogena y proceso de produccion que utiliza la celula.
WO2008153029A1 (ja) 特異的遺伝子発現方法
WO2008114673A1 (ja) ポリペプチドの製造方法
MX2010001319A (es) Metodo para producir proteinas heterogeneas.
MY185887A (en) Cell culture improvements
MX2019002498A (es) Metodos y productos para la expresion de proteinas en celulas.
SG10201901417UA (en) Production of proteins in glutamine-free cell culture media
MX387605B (es) Supercontigos de proteina basados en repeticiones de fibronectina tipo iii con superficies de union alternativas
NZ603996A (en) Cells or cell lines that stably express a bitter taste receptor and methods of making them
MX2012006602A (es) Metodos y organismos para convertir el gas de sintesis u otras fuentes de carbono gaseoso y metanol a 1, 3 - butanodiol.
MX2012009175A (es) Metodos para identificar y aislar celulas que expresan un polipeptido.
WO2009114702A3 (en) Recombinant production of authentic human proteins using human cell expression systems
MX2013003681A (es) Ácidos nucleicos manipulados y métodos de uso de los mismos.
WO2009120762A3 (en) Human cardiovascular progenitor cells
SG10201810830UA (en) Cell culture compositions and methods for polypeptide production
WO2007130543A3 (en) Method for producing stable mammalian cell lines producing high levels of recombinant proteins
WO2009051109A1 (ja) 異種タンパク質を高生産する細胞の作製方法
WO2011072119A3 (en) Stem-cell material and method of use
EA201000273A1 (ru) Белок-предшественник тиопептида, кодирующий его ген и его применение
PL1720979T3 (pl) Zastosowanie podłoża pozbawionego surowicy do hodowli komórkowej do wytwarzania IL-18BP w komórkach ssaków
WO2005087802A3 (en) Process for producing polypeptides
MX2012003816A (es) Construccion de adn y procedimiento para la generacion de celulas cho recombinantes usando la misma.
MX2013011355A (es) Metodo de produccion de polipeptido recombinante.
EP1939283A4 (en) PROCESS FOR PRODUCING RECOMBINANT HUMAN THROMBIN BY A CULTIVATED CELL
MX2013005749A (es) Composiciones y metodos para producir enterocinasa en levaduras.

Legal Events

Date Code Title Description
FG Grant or registration