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MX2010001723A - Formulations of antibodies and fc-fusion molecules using polycations. - Google Patents

Formulations of antibodies and fc-fusion molecules using polycations.

Info

Publication number
MX2010001723A
MX2010001723A MX2010001723A MX2010001723A MX2010001723A MX 2010001723 A MX2010001723 A MX 2010001723A MX 2010001723 A MX2010001723 A MX 2010001723A MX 2010001723 A MX2010001723 A MX 2010001723A MX 2010001723 A MX2010001723 A MX 2010001723A
Authority
MX
Mexico
Prior art keywords
polycations
formulations
antibodies
fusion molecules
antibody
Prior art date
Application number
MX2010001723A
Other languages
Spanish (es)
Inventor
Tiansheng Li
Pavel Bondarenko
Christopher James Sloey
Gang Xiao
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MX2010001723A publication Critical patent/MX2010001723A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates, in general, to methods for preparing antibody and Fc-fusion molecule formulations, wherein the antibody or Fc-fusion molecule is in a formulation comprising polycations. The invention also provides compositions comprising an antibody or Fc-fusion molecule and a polycation.
MX2010001723A 2007-08-17 2008-08-15 Formulations of antibodies and fc-fusion molecules using polycations. MX2010001723A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95651407P 2007-08-17 2007-08-17
PCT/US2008/073250 WO2009026122A1 (en) 2007-08-17 2008-08-15 Formulations of antibodies and fc-fusion molecules using polycations

Publications (1)

Publication Number Publication Date
MX2010001723A true MX2010001723A (en) 2010-04-30

Family

ID=40014979

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010001723A MX2010001723A (en) 2007-08-17 2008-08-15 Formulations of antibodies and fc-fusion molecules using polycations.

Country Status (6)

Country Link
EP (1) EP2190476A1 (en)
JP (1) JP2010536786A (en)
AU (1) AU2008289225A1 (en)
CA (1) CA2696049A1 (en)
MX (1) MX2010001723A (en)
WO (1) WO2009026122A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7767206B2 (en) 2006-10-02 2010-08-03 Amgen Inc. Neutralizing determinants of IL-17 Receptor A and antibodies that bind thereto
US8221753B2 (en) 2009-09-30 2012-07-17 Tracon Pharmaceuticals, Inc. Endoglin antibodies
SG10201604093XA (en) 2010-01-15 2016-07-28 Kirin Amgen Inc Antibody formulation and therapeutic regimens
CN102585016B (en) * 2012-03-06 2014-06-04 江苏健德生物药业有限公司 Immune fusion protein capable of inhibiting T and B lymphocyte functions and preparation method and application thereof
US8883979B2 (en) 2012-08-31 2014-11-11 Bayer Healthcare Llc Anti-prolactin receptor antibody formulations
UA115789C2 (en) 2012-09-05 2017-12-26 Трейкон Фармасутікалз, Інк. Antibody formulations and uses thereof
CN103232542B (en) * 2013-02-01 2015-05-13 殷勇 Double-target chimeric protein
IL312865B1 (en) 2013-09-11 2025-02-01 Eagle Biologics Inc Liquid protein formulations containing viscosity-lowering agents
JP6444310B2 (en) 2013-10-28 2018-12-26 テルモ株式会社 Method for stabilizing monoclonal antibodies
JP6716577B2 (en) 2014-10-01 2020-07-01 イーグル・バイオロジクス・インコーポレイテッドＥａｇｌｅ Ｂｉｏｌｏｇｉｃｓ， Ｉｎｃ． Pharmaceutical preparations of polysaccharides and nucleic acids containing viscosity reducing substances
CA3235178A1 (en) * 2017-03-01 2018-09-07 Medimmmune Limited Formulations of monoclonal antibodies
JP7104929B2 (en) * 2017-07-24 2022-07-22 テルモ株式会社 Method for producing complex containing medical protein and polyamino acid, and complex containing medical protein and polyamino acid
WO2024181580A1 (en) * 2023-03-02 2024-09-06 国立研究開発法人科学技術振興機構 Lipid nanoparticles, pharmaceutical composition, and production method for lipid nanoparticles

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8904370D0 (en) * 1989-02-25 1989-04-12 Cosmas Damian Ltd Liquid delivery compositions
EP0565618A4 (en) * 1991-01-03 1994-06-29 Alkermes Inc Stabilization of proteins by cationic biopolymers
DE4110409C2 (en) * 1991-03-29 1999-05-27 Boehringer Ingelheim Int New protein-polycation conjugates
US5521291A (en) * 1991-09-30 1996-05-28 Boehringer Ingelheim International, Gmbh Conjugates for introducing nucleic acid into higher eucaryotic cells
GB9320782D0 (en) * 1993-10-08 1993-12-01 Univ Leeds Innovations Ltd Stabilising of proteins on solution
US6660843B1 (en) * 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents

Also Published As

Publication number Publication date
EP2190476A1 (en) 2010-06-02
CA2696049A1 (en) 2009-02-26
AU2008289225A1 (en) 2009-02-26
JP2010536786A (en) 2010-12-02
WO2009026122A1 (en) 2009-02-26

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal