MX2010000166A - Metodos para generar respuesta inmune usando liberacion de acido nucleico mediada por liposoma cationico. - Google Patents
Metodos para generar respuesta inmune usando liberacion de acido nucleico mediada por liposoma cationico.Info
- Publication number
- MX2010000166A MX2010000166A MX2010000166A MX2010000166A MX2010000166A MX 2010000166 A MX2010000166 A MX 2010000166A MX 2010000166 A MX2010000166 A MX 2010000166A MX 2010000166 A MX2010000166 A MX 2010000166A MX 2010000166 A MX2010000166 A MX 2010000166A
- Authority
- MX
- Mexico
- Prior art keywords
- liposome
- cationic
- diated
- methods
- nucleic acid
- Prior art date
Links
- 230000028993 immune response Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 239000002502 liposome Substances 0.000 abstract 2
- 230000003612 virological effect Effects 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 125000002091 cationic group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 230000008685 targeting Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
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- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
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- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
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Abstract
La presente invenci?n est? en el campo de la liberaci?n o distribuci?n de f?rmacos, y espec?ficamente, vacunas basadas en liposoma cati?nico. En modalidades, esta invenci?n proporciona m?todos para producir liposomas dirigidos al ligando (por ejemplo, dirigidos al anticuerpo o fragmento de anticuerpo) ?tiles para la liberaci?n o distribuci?n de mol?culas para inducir respuestas inmunes contra ant?genos o para tratar o prevenir enfermedades virales. La especificidad del sistema de liberaci?n o distribuci?n se deriva de los ligando directores.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US92968507P | 2007-07-09 | 2007-07-09 | |
PCT/US2008/008394 WO2009009054A1 (en) | 2007-07-09 | 2008-07-09 | Methods for generating immune response using cationic-liposome-mediated nucleic acid delivery |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010000166A true MX2010000166A (es) | 2010-04-27 |
Family
ID=40228915
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010000166A MX2010000166A (es) | 2007-07-09 | 2008-07-09 | Metodos para generar respuesta inmune usando liberacion de acido nucleico mediada por liposoma cationico. |
Country Status (15)
Country | Link |
---|---|
US (1) | US20090053299A1 (es) |
EP (1) | EP2175835B1 (es) |
JP (2) | JP5890095B2 (es) |
KR (2) | KR20150108948A (es) |
CN (2) | CN106890142A (es) |
AU (1) | AU2008275713B2 (es) |
BR (1) | BRPI0814558A2 (es) |
CA (1) | CA2692546C (es) |
EA (1) | EA201070050A1 (es) |
IL (1) | IL203204B (es) |
MX (1) | MX2010000166A (es) |
NZ (1) | NZ582414A (es) |
SG (1) | SG182994A1 (es) |
WO (1) | WO2009009054A1 (es) |
ZA (1) | ZA201000038B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
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JP5573111B2 (ja) * | 2009-11-06 | 2014-08-20 | ライオン株式会社 | イソプロピルメチルフェノール含有液体口腔用組成物 |
US20110182976A1 (en) * | 2010-01-28 | 2011-07-28 | National Taiwan Ocean University | Lipoplex-patch based dna vaccine |
JP5835741B2 (ja) * | 2010-02-26 | 2015-12-24 | 国立大学法人 長崎大学 | 抗原または薬物送達複合体 |
SMT202300096T1 (it) * | 2010-08-31 | 2023-05-12 | Glaxosmithkline Biologicals Sa | Liposomi piccoli per la somministrazione di rna codificante un immunogeno |
WO2012040101A1 (en) | 2010-09-21 | 2012-03-29 | University Of Miami | Compositions and methods for inducing migration by dendritic cells and an immune response |
WO2012040266A2 (en) * | 2010-09-24 | 2012-03-29 | University Of Miami | Gene-based adjuvants and compositions thereof to increase antibody production in response to gene-based vaccines |
US20140120157A1 (en) | 2012-09-19 | 2014-05-01 | Georgetown University | Targeted liposomes |
EP2711000B1 (en) * | 2012-09-19 | 2019-04-03 | Georgetown University | Targeted Liposomes |
CN103405386B (zh) * | 2012-09-21 | 2016-05-18 | 上海泽润生物科技有限公司 | 一种脂质体的制备方法及制作脂质体佐剂的方法 |
CN105163762B (zh) * | 2013-03-14 | 2019-06-25 | 乔治敦大学 | 对神经毒剂的暴露的治疗 |
CN105726485B (zh) * | 2016-03-24 | 2019-08-06 | 东华大学 | 一种半乳糖化壳聚糖修饰的免疫醇质体的制备方法 |
EP3891123A4 (en) | 2018-12-03 | 2022-12-14 | Board of Regents, The University of Texas System | ANALOGS OF OLIGO-BENZAMIDE AND THEIR USE IN THE TREATMENT OF CANCER |
CN111840538A (zh) * | 2020-05-29 | 2020-10-30 | 中山大学 | 一种水痘-带状疱疹病毒亚单位纳米疫苗的制备方法和应用 |
CN117883382B (zh) * | 2023-11-27 | 2025-02-14 | 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) | 高效递送疫苗的脂质体载体及脂质体疫苗的制备与用途 |
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US4957735A (en) * | 1984-06-12 | 1990-09-18 | The University Of Tennessee Research Corporation | Target-sensitive immunoliposomes- preparation and characterization |
US4946778A (en) * | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
US5688488A (en) * | 1989-04-03 | 1997-11-18 | Purdue Research Foundation | Composition and method for tumor imaging |
US5753258A (en) * | 1990-10-19 | 1998-05-19 | University Of Florida | Artificial viral envelopes |
US6099842A (en) * | 1990-12-03 | 2000-08-08 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant immunotoxin composed of a single chain antibody reacting with the human transferrin receptor and diptheria toxin |
DE69332485T2 (de) * | 1992-08-11 | 2003-11-13 | The President And Fellows Of Harvard College, Cambridge | Immunmodulierende peptide |
US5786214A (en) * | 1994-12-15 | 1998-07-28 | Spinal Cord Society | pH-sensitive immunoliposomes and method of gene delivery to the mammalian central nervous system |
FR2730637B1 (fr) * | 1995-02-17 | 1997-03-28 | Rhone Poulenc Rorer Sa | Composition pharmaceutique contenant des acides nucleiques, et ses utilisations |
WO1997000271A1 (en) * | 1995-06-14 | 1997-01-03 | The Regents Of The University Of California | Novel high affinity human antibodies to tumor antigens |
US6210707B1 (en) * | 1996-11-12 | 2001-04-03 | The Regents Of The University Of California | Methods of forming protein-linked lipidic microparticles, and compositions thereof |
EP0956001B1 (en) * | 1996-11-12 | 2012-09-12 | The Regents of The University of California | Preparation of stable formulations of lipid-nucleic acid complexes for efficient in vivo delivery |
US6794128B2 (en) * | 1998-04-24 | 2004-09-21 | The Regents Of The University Of California | Methods of selecting internalizing antibodies |
US20030022854A1 (en) * | 1998-06-25 | 2003-01-30 | Dow Steven W. | Vaccines using nucleic acid-lipid complexes |
DE60032739T2 (de) * | 1999-02-22 | 2007-05-24 | Georgetown University | Immunoliposome mit einem targeting-antikörperfragment zur systemischen genverabreichung |
US7780882B2 (en) * | 1999-02-22 | 2010-08-24 | Georgetown University | Simplified and improved method for preparing an antibody or an antibody fragment targeted immunoliposome for systemic administration of a therapeutic or diagnostic agent |
US9034329B2 (en) * | 1999-02-22 | 2015-05-19 | Georgetown University | Preparation of antibody or an antibody fragment-targeted immunoliposomes for systemic administration of therapeutic or diagnostic agents and uses thereof |
US20020103165A1 (en) * | 2000-02-29 | 2002-08-01 | Alliance Pharmaceutical Corp., | Engineered spray-dried lipid-based microparticles for cellular targeting |
US20050002998A1 (en) | 2003-06-04 | 2005-01-06 | Georgetown University | Method for improving stability and shelf-life of liposome complexes |
AU2006304790B2 (en) * | 2005-10-20 | 2013-06-27 | Georgetown University | Tumor-targeted nanodelivery systems to improve early MRI detection of cancer |
-
2008
- 2008-07-09 KR KR1020157025507A patent/KR20150108948A/ko not_active Withdrawn
- 2008-07-09 EP EP08780044.7A patent/EP2175835B1/en active Active
- 2008-07-09 JP JP2010516041A patent/JP5890095B2/ja not_active Expired - Fee Related
- 2008-07-09 AU AU2008275713A patent/AU2008275713B2/en not_active Ceased
- 2008-07-09 CN CN201710070091.XA patent/CN106890142A/zh active Pending
- 2008-07-09 SG SG2012049664A patent/SG182994A1/en unknown
- 2008-07-09 CN CN200880105375A patent/CN101801344A/zh active Pending
- 2008-07-09 WO PCT/US2008/008394 patent/WO2009009054A1/en active Application Filing
- 2008-07-09 NZ NZ582414A patent/NZ582414A/xx not_active IP Right Cessation
- 2008-07-09 US US12/216,715 patent/US20090053299A1/en not_active Abandoned
- 2008-07-09 BR BRPI0814558-0A2A patent/BRPI0814558A2/pt not_active Application Discontinuation
- 2008-07-09 MX MX2010000166A patent/MX2010000166A/es active IP Right Grant
- 2008-07-09 CA CA2692546A patent/CA2692546C/en active Active
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US20090053299A1 (en) | 2009-02-26 |
CN106890142A (zh) | 2017-06-27 |
SG182994A1 (en) | 2012-08-30 |
HK1143532A1 (zh) | 2011-01-07 |
EP2175835A1 (en) | 2010-04-21 |
CA2692546A1 (en) | 2009-01-15 |
CA2692546C (en) | 2018-03-13 |
CN101801344A (zh) | 2010-08-11 |
JP5890095B2 (ja) | 2016-03-22 |
KR101570886B1 (ko) | 2015-11-23 |
AU2008275713A1 (en) | 2009-01-15 |
KR20150108948A (ko) | 2015-09-30 |
EP2175835A4 (en) | 2011-08-03 |
BRPI0814558A2 (pt) | 2015-01-06 |
KR20100044206A (ko) | 2010-04-29 |
AU2008275713B2 (en) | 2014-08-07 |
JP2014148533A (ja) | 2014-08-21 |
IL203204B (en) | 2018-05-31 |
WO2009009054A1 (en) | 2009-01-15 |
ZA201000038B (en) | 2011-03-30 |
EA201070050A1 (ru) | 2010-10-29 |
JP2010533178A (ja) | 2010-10-21 |
NZ582414A (en) | 2012-09-28 |
EP2175835B1 (en) | 2016-04-20 |
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