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MX2009013663A - Formulacion solubilizada de docetaxel sin tween 80. - Google Patents

Formulacion solubilizada de docetaxel sin tween 80.

Info

Publication number
MX2009013663A
MX2009013663A MX2009013663A MX2009013663A MX2009013663A MX 2009013663 A MX2009013663 A MX 2009013663A MX 2009013663 A MX2009013663 A MX 2009013663A MX 2009013663 A MX2009013663 A MX 2009013663A MX 2009013663 A MX2009013663 A MX 2009013663A
Authority
MX
Mexico
Prior art keywords
docetaxel
tween
ready
avoided
solubilized formulation
Prior art date
Application number
MX2009013663A
Other languages
English (en)
Inventor
Nageswara R Palepu
Bhanu Teja Bulusu
Original Assignee
Scidose Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scidose Llc filed Critical Scidose Llc
Publication of MX2009013663A publication Critical patent/MX2009013663A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Los liofilizados que contienen docetaxel y el uso de los mismos para preparar formulaciones de líquido concentradas, y formulaciones listas para uso para inyección, así como tales concentrados y formulaciones listas para uso mismas se describen en los que los tensoactivos de Tween se evitan de modo que las reacciones de hipersensibilidad para los tensoactivos de Tween pueden evitarse y el docetaxel puede administrarse en dosis más altas y/o durante periodos más largos de tiempo y/o para ciclos de tratamiento adicionales.
MX2009013663A 2007-06-22 2008-06-19 Formulacion solubilizada de docetaxel sin tween 80. MX2009013663A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US93676307P 2007-06-22 2007-06-22
US6622008P 2008-02-19 2008-02-19
PCT/US2008/007619 WO2009002425A2 (en) 2007-06-22 2008-06-19 Solubilized formulation of docetaxel without tween 80

Publications (1)

Publication Number Publication Date
MX2009013663A true MX2009013663A (es) 2010-01-27

Family

ID=40137154

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009013663A MX2009013663A (es) 2007-06-22 2008-06-19 Formulacion solubilizada de docetaxel sin tween 80.

Country Status (11)

Country Link
US (2) US20080319048A1 (es)
EP (1) EP2170319A4 (es)
JP (1) JP2010530872A (es)
KR (1) KR20100023862A (es)
CN (1) CN101677987A (es)
AU (1) AU2008269179A1 (es)
CA (1) CA2686225A1 (es)
IL (1) IL202728A0 (es)
MX (1) MX2009013663A (es)
NZ (1) NZ581589A (es)
WO (1) WO2009002425A2 (es)

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CA2716576A1 (en) 2008-03-07 2009-09-11 Nageswara R. Palepu Fulvestrant formulations
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US7772274B1 (en) 2009-10-19 2010-08-10 Scidose, Llc Docetaxel formulations with lipoic acid
US8541465B2 (en) * 2009-10-19 2013-09-24 Scidose, Llc Docetaxel formulations with lipoic acid and/or dihydrolipoic acid
US20120065255A1 (en) * 2009-10-19 2012-03-15 Nagesh Palepu Cabazitaxel formulations and methods of preparing thereof
US20110092579A1 (en) * 2009-10-19 2011-04-21 Scidose Llc Solubilized formulation of docetaxel
US8476310B2 (en) 2009-10-19 2013-07-02 Scidose Llc Docetaxel formulations with lipoic acid
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JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
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TWI752750B (zh) 2015-09-30 2022-01-11 香港商慧源香港創新有限公司 口服紫杉烷組合物及方法
TWI841554B (zh) 2018-03-21 2024-05-11 丹麥商珍美寶股份有限公司 以鉑為主之劑與抗組織因子抗體－藥物共軛物的組合治療癌症之方法
EP3866783A4 (en) 2018-10-16 2022-08-03 US Nano Food & Drug Inc Intratumor injection formulation
CN112704677A (zh) * 2019-10-24 2021-04-27 慧禹康成(杭州)医药科技有限公司 维生素e类化合物的用途
CN118903094A (zh) * 2020-02-04 2024-11-08 珠海贝海生物技术有限公司 多西他赛制剂
EP4135686A4 (en) 2020-04-13 2025-03-12 US Nano Food & Drug INC BASIC CHEMOTHERAPEUTIC INTRATUMORAL INJECTION FORMULATION

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Also Published As

Publication number Publication date
JP2010530872A (ja) 2010-09-16
US20080319048A1 (en) 2008-12-25
US20120264817A1 (en) 2012-10-18
WO2009002425A3 (en) 2009-12-30
EP2170319A4 (en) 2011-10-12
WO2009002425A2 (en) 2008-12-31
KR20100023862A (ko) 2010-03-04
EP2170319A2 (en) 2010-04-07
CN101677987A (zh) 2010-03-24
IL202728A0 (en) 2010-06-30
CA2686225A1 (en) 2008-12-31
NZ581589A (en) 2012-10-26
AU2008269179A1 (en) 2008-12-31

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