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MX2009007045A - Ciclosporina no inmunosupresora para el tratamiento de distrofia muscular congenita de ullrich. - Google Patents

Ciclosporina no inmunosupresora para el tratamiento de distrofia muscular congenita de ullrich.

Info

Publication number
MX2009007045A
MX2009007045A MX2009007045A MX2009007045A MX2009007045A MX 2009007045 A MX2009007045 A MX 2009007045A MX 2009007045 A MX2009007045 A MX 2009007045A MX 2009007045 A MX2009007045 A MX 2009007045A MX 2009007045 A MX2009007045 A MX 2009007045A
Authority
MX
Mexico
Prior art keywords
muscular dystrophy
treatment
congenital muscular
ullrich congenital
immunosuppressive cyclosporin
Prior art date
Application number
MX2009007045A
Other languages
English (en)
Inventor
Gregoire Vuagniaux
Paolo Bernardi
Rafael Crabbe
Original Assignee
Debiopharm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Debiopharm Sa filed Critical Debiopharm Sa
Publication of MX2009007045A publication Critical patent/MX2009007045A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La presente invención se relaciona con el uso de un derivado de ciclosporina A no inmunosupresor para reducir la disfunción mitocondrial y la velocidad de apoptosis de las células musculares de pacientes a los que sé les ha diagnosticado distrofia muscular congénita de Ullrich o miopatía de Bethlem.
MX2009007045A 2007-01-04 2008-01-03 Ciclosporina no inmunosupresora para el tratamiento de distrofia muscular congenita de ullrich. MX2009007045A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87841407P 2007-01-04 2007-01-04
PCT/IB2008/000003 WO2008084368A2 (en) 2007-01-04 2008-01-03 Non-immunosuppressive cyclosporin for treatment of ullrich congenital muscular dystrophy

Publications (1)

Publication Number Publication Date
MX2009007045A true MX2009007045A (es) 2009-10-07

Family

ID=39514754

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009007045A MX2009007045A (es) 2007-01-04 2008-01-03 Ciclosporina no inmunosupresora para el tratamiento de distrofia muscular congenita de ullrich.

Country Status (12)

Country Link
US (1) US8450281B2 (es)
EP (1) EP2124992A2 (es)
JP (1) JP5801534B2 (es)
CN (2) CN101616683A (es)
AU (1) AU2008204344B2 (es)
BR (1) BRPI0806265A2 (es)
CA (1) CA2674296C (es)
HK (1) HK1210951A1 (es)
IL (1) IL199674A (es)
MX (1) MX2009007045A (es)
RU (1) RU2462262C2 (es)
WO (1) WO2008084368A2 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009098533A1 (en) * 2008-02-08 2009-08-13 Debiopharm Sa Non -immunosuppressive cyclosporin for the treatment of muscular dystrophy
WO2011098805A1 (en) 2010-02-09 2011-08-18 Biotica Technology Limited Sanglifehrin based compounds
WO2011098808A1 (en) 2010-02-09 2011-08-18 Biotica Technology Limited Sanglifehrin based compounds
ES2541853T3 (es) 2010-02-09 2015-07-27 Neurovive Pharmaceutical Ab Compuestos basados en sangliferina
GB201008123D0 (en) 2010-05-17 2010-06-30 Biotica Tech Ltd Novel compounds
CA3028414C (en) 2010-12-20 2021-01-26 Neurovive Pharmaceutical Ab Sanglifehrin derivatives and methods for their production
JO3063B1 (ar) 2011-03-29 2017-03-15 Neurovive Pharmaceutical Ab مركب مبتكر وطرق لانتاجه
CA2872162A1 (en) 2012-05-07 2013-11-14 Novartis Ag Pharmacokinetic modulation with alisporivir
AR090964A1 (es) 2012-05-09 2014-12-17 Novartis Ag Proceso para la elaboracion de undecapeptidos ciclicos

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3884470T2 (de) * 1987-06-17 1994-03-10 Sandoz Ag Cyclosporine und deren Benutzung als Arzneimittel.
KR0148748B1 (ko) 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
CA2329709A1 (en) * 1998-04-24 1999-11-04 Mitokor Compounds and methods for treating mitochondria-associated diseases
PT1091975E (pt) * 1998-07-01 2006-05-31 Debiopharm Sa Nova ciclosporina com um perfil de actividade melhorado
US6323039B1 (en) * 1999-06-22 2001-11-27 Mitokor Compositions and methods for assaying subcellular conditions and processes using energy transfer
US7368423B1 (en) 2001-12-05 2008-05-06 The Scripps Research Institute Composition and method for treating chronic allograft rejection
GB0320638D0 (en) 2003-09-03 2003-10-01 Novartis Ag Organic compounds
WO2009098533A1 (en) * 2008-02-08 2009-08-13 Debiopharm Sa Non -immunosuppressive cyclosporin for the treatment of muscular dystrophy

Also Published As

Publication number Publication date
IL199674A0 (en) 2010-04-15
JP2010514834A (ja) 2010-05-06
CN105056207A (zh) 2015-11-18
WO2008084368A2 (en) 2008-07-17
AU2008204344B2 (en) 2013-01-31
AU2008204344A9 (en) 2012-06-28
CN101616683A (zh) 2009-12-30
EP2124992A2 (en) 2009-12-02
HK1210951A1 (en) 2016-05-13
IL199674A (en) 2016-10-31
CA2674296A1 (en) 2008-07-17
JP5801534B2 (ja) 2015-10-28
RU2462262C2 (ru) 2012-09-27
BRPI0806265A2 (pt) 2011-09-06
US8450281B2 (en) 2013-05-28
AU2008204344A1 (en) 2008-07-17
WO2008084368A8 (en) 2009-09-17
WO2008084368A9 (en) 2009-02-26
RU2009129212A (ru) 2011-02-10
US20100041593A1 (en) 2010-02-18
CA2674296C (en) 2015-11-24

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