MX2007009960A - Combinaciones y metodos de administracion de agentes terapeuticos y terapia de combinacion. - Google Patents
Combinaciones y metodos de administracion de agentes terapeuticos y terapia de combinacion.Info
- Publication number
- MX2007009960A MX2007009960A MX2007009960A MX2007009960A MX2007009960A MX 2007009960 A MX2007009960 A MX 2007009960A MX 2007009960 A MX2007009960 A MX 2007009960A MX 2007009960 A MX2007009960 A MX 2007009960A MX 2007009960 A MX2007009960 A MX 2007009960A
- Authority
- MX
- Mexico
- Prior art keywords
- administration
- combinations
- combination therapy
- modes
- therapeutic agents
- Prior art date
Links
- 238000002648 combination therapy Methods 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 229940124597 therapeutic agent Drugs 0.000 title 1
- 229940123237 Taxane Drugs 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000002105 nanoparticle Substances 0.000 abstract 2
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 abstract 2
- 238000002560 therapeutic procedure Methods 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 229940127089 cytotoxic agent Drugs 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
- 238000001356 surgical procedure Methods 0.000 abstract 1
Classifications
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- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
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Abstract
La presente invencion proporciona metodos de terapia de combinacion para tratar enfermedades proliferativas (tal como cancer) que comprende una primera terapia que comprende administrar a un individuo una cantidad efectiva de un taxano en una composicion en nanoparticulas, y una segunda terapia que puede incluir, por ejemplo, radiacion, cirugia, administracion de agentes quimioterapeuticos, o combinaciones de los mismos. Tambien se proporcionan metodos para administrar a un individuo un farmaco de taxano en una composicion de nanoparticulas en base a un regimen de dosificacion metronomica.
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