MX167808B - Metodo para separar hidrocloruro de l-cisteina munhidratado - Google Patents
Metodo para separar hidrocloruro de l-cisteina munhidratadoInfo
- Publication number
- MX167808B MX167808B MX006977A MX697787A MX167808B MX 167808 B MX167808 B MX 167808B MX 006977 A MX006977 A MX 006977A MX 697787 A MX697787 A MX 697787A MX 167808 B MX167808 B MX 167808B
- Authority
- MX
- Mexico
- Prior art keywords
- solution
- separate
- cysteine
- cysteine hydrochloride
- munhydrated
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- VLSOAXRVHARBEQ-UHFFFAOYSA-N [4-fluoro-2-(hydroxymethyl)phenyl]methanol Chemical compound OCC1=CC=C(F)C=C1CO VLSOAXRVHARBEQ-UHFFFAOYSA-N 0.000 title 1
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 abstract 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 4
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 abstract 2
- LEVWYRKDKASIDU-IMJSIDKUSA-N L-cystine Chemical compound [O-]C(=O)[C@@H]([NH3+])CSSC[C@H]([NH3+])C([O-])=O LEVWYRKDKASIDU-IMJSIDKUSA-N 0.000 abstract 2
- 235000019393 L-cystine Nutrition 0.000 abstract 2
- 239000004158 L-cystine Substances 0.000 abstract 2
- 229960003067 cystine Drugs 0.000 abstract 2
- 229960001153 serine Drugs 0.000 abstract 2
- PWKSKIMOESPYIA-UHFFFAOYSA-N 2-acetamido-3-sulfanylpropanoic acid Chemical compound CC(=O)NC(CS)C(O)=O PWKSKIMOESPYIA-UHFFFAOYSA-N 0.000 abstract 1
- 235000013878 L-cysteine Nutrition 0.000 abstract 1
- 239000004201 L-cysteine Substances 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 229960002433 cysteine Drugs 0.000 abstract 1
- 229910017053 inorganic salt Inorganic materials 0.000 abstract 1
- 150000004682 monohydrates Chemical class 0.000 abstract 1
- LJPYJRMMPVFEKR-UHFFFAOYSA-N prop-2-ynylurea Chemical compound NC(=O)NCC#C LJPYJRMMPVFEKR-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/12—Methionine; Cysteine; Cystine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La presente invención se refiere a un método para separar L-cisteína de una solución que contiene L-cisteína, L-cistina, L-serina y una sal inorgánica, caracterizado porque comprende: agregar ácido clorhídrico a la solución hasta que contenga cuando menos 15 por ciento en peso de ácido clorhídrico, mantener la solución a una temperatura de cuando menos 20 grados centígrados, para separar un sólido que contiene la L-cistina y la sal de la solución; enfriar la solución a una temperatura no superior a los 10 grados centígrados para mantener la cristalización forme el hidrocloruro del L-cisteína monohidratado; y separar el monohidrato, de la L-serina en la solución.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61141425A JPH0623182B2 (ja) | 1986-06-19 | 1986-06-19 | Ｌ−システイン塩酸塩１水和物を分離する方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX167808B true MX167808B (es) | 1993-04-13 |
Family
ID=15291689
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX006977A MX167808B (es) | 1986-06-19 | 1987-06-18 | Metodo para separar hidrocloruro de l-cisteina munhidratado |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4733010A (es) |
| EP (1) | EP0250987B1 (es) |
| JP (1) | JPH0623182B2 (es) |
| KR (1) | KR900001610B1 (es) |
| CN (1) | CN87104339A (es) |
| AU (1) | AU578183B2 (es) |
| CA (1) | CA1285958C (es) |
| DE (1) | DE3767052D1 (es) |
| MX (1) | MX167808B (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5756319A (en) * | 1995-07-18 | 1998-05-26 | Mitsui Toatsu Chemicals, Inc. | Production process of S-phenyl-L-cysteine |
| US7348037B2 (en) * | 2002-08-16 | 2008-03-25 | Evonik Degussa Gmbh | Sulfur-containing animal-feed additives |
| DE102007007333A1 (de) | 2007-02-14 | 2008-08-21 | Wacker Chemie Ag | Verfahren zur Reinigung von L-Cystein |
| CN102517352B (zh) * | 2011-12-28 | 2014-09-24 | 南京大学 | L-半胱氨酸酶法转化制备方法 |
| KR101959061B1 (ko) * | 2017-03-22 | 2019-03-18 | 대상 주식회사 | L-시스테인 염산염의 제조 방법 |
| KR20190092950A (ko) * | 2018-01-31 | 2019-08-08 | 씨제이제일제당 (주) | 연속식 크로마토그래피 공정을 이용한 천연 l-시스테인 염산염 수화물 결정의 제조 방법 |
| KR20190092951A (ko) * | 2018-01-31 | 2019-08-08 | 씨제이제일제당 (주) | 연속식 크로마토그래피 공정을 이용한 천연 l-시스테인 결정의 제조 방법 |
| CN110857474B (zh) * | 2018-08-24 | 2023-04-18 | 武汉远大弘元股份有限公司 | L-半胱氨酸盐酸盐一水合物的处理方法 |
| KR102831417B1 (ko) * | 2023-02-07 | 2025-07-09 | 씨제이제일제당 주식회사 | 입도가 조절된 l-시스테인 염산염 수화물 결정의 제조 방법 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2178510A (en) * | 1938-06-20 | 1939-10-31 | Corn Prod Refining Co | Removal of chlorides from solutions of amino acids |
| US2456742A (en) * | 1947-01-10 | 1948-12-21 | Merck & Co Inc | Separation of isomers of amino acids |
| DE907175C (de) * | 1952-01-17 | 1954-03-22 | Diamalt Ag | Verfahren zur Gewinnung von Cystin aus Gemischen verschiedener Aminosaeuren |
| US2816915A (en) * | 1953-11-20 | 1957-12-17 | Du Pont | Separation of phenyl-serines |
| US2898358A (en) * | 1957-07-29 | 1959-08-04 | Int Minerals & Chem Corp | Resolution of enantiomorphic mixtures |
| US3433832A (en) * | 1965-12-03 | 1969-03-18 | Dow Chemical Co | Recovery of alpha-aminocarboxylic acids from sodium chloride solutions |
| JPS57200356A (en) * | 1981-06-01 | 1982-12-08 | Mitsui Toatsu Chem Inc | Preparation of dl-cysteine |
| US4613688A (en) * | 1982-04-02 | 1986-09-23 | Showa Denko Kabushiki Kaisha | Optical resolution process for DL-cysteine |
| JPS61242589A (ja) * | 1985-04-22 | 1986-10-28 | Mitsui Toatsu Chem Inc | Ｌ−含硫アミノ酸の製造方法 |
| CA1299128C (en) * | 1986-11-19 | 1992-04-21 | Tooru Miyahara | Method of producing l-cystine |
-
1986
- 1986-06-19 JP JP61141425A patent/JPH0623182B2/ja not_active Expired - Fee Related
-
1987
- 1987-06-09 US US07/059,845 patent/US4733010A/en not_active Expired - Fee Related
- 1987-06-10 CA CA000539334A patent/CA1285958C/en not_active Expired - Lifetime
- 1987-06-12 DE DE8787108503T patent/DE3767052D1/de not_active Expired - Lifetime
- 1987-06-12 EP EP87108503A patent/EP0250987B1/en not_active Expired - Lifetime
- 1987-06-17 KR KR1019870006122A patent/KR900001610B1/ko not_active Expired
- 1987-06-18 MX MX006977A patent/MX167808B/es unknown
- 1987-06-18 CN CN198787104339A patent/CN87104339A/zh active Pending
- 1987-06-18 AU AU74459/87A patent/AU578183B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0250987A1 (en) | 1988-01-07 |
| CN87104339A (zh) | 1988-06-01 |
| JPS62298571A (ja) | 1987-12-25 |
| AU7445987A (en) | 1987-12-24 |
| US4733010A (en) | 1988-03-22 |
| EP0250987B1 (en) | 1990-12-27 |
| CA1285958C (en) | 1991-07-09 |
| DE3767052D1 (de) | 1991-02-07 |
| KR900001610B1 (ko) | 1990-03-17 |
| AU578183B2 (en) | 1988-10-13 |
| KR880000389A (ko) | 1988-03-25 |
| JPH0623182B2 (ja) | 1994-03-30 |
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