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MD20160079A2 - Sistem de livrare a medicamentului - Google Patents

Sistem de livrare a medicamentului Download PDF

Info

Publication number
MD20160079A2
MD20160079A2 MDA20160079A MD20160079A MD20160079A2 MD 20160079 A2 MD20160079 A2 MD 20160079A2 MD A20160079 A MDA20160079 A MD A20160079A MD 20160079 A MD20160079 A MD 20160079A MD 20160079 A2 MD20160079 A2 MD 20160079A2
Authority
MD
Moldova
Prior art keywords
thermoplastic polymer
therapeutic agent
delivery system
drug delivery
core
Prior art date
Application number
MDA20160079A
Other languages
English (en)
Russian (ru)
Inventor
Вилли Дж. ВЕРХОВЕН
Граафф Воутер де
Original Assignee
Merck Sharp & Dohme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme Corp filed Critical Merck Sharp & Dohme Corp
Publication of MD20160079A2 publication Critical patent/MD20160079A2/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

În prezenta invenţie este descris un sistem intravaginal de livrare a medicamentului, care include un nucleu, care conţine un polimer termoplastic şi un agent terapeutic, în care agentul terapeutic este dizolvat în polimerul termoplastic, o membrană, care înconjoară nucleul şi conţine un alt polimer termoplastic, în care agentul terapeutic are o permeabilitate mai redusă în al doilea polimer termoplastic decât în primul polimer termoplastic, şi un alt agent terapeutic în formă solidă inclus într-o porţiune a membranei.
MDA20160079A 2013-12-11 2014-12-08 Sistem de livrare a medicamentului MD20160079A2 (ro)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361914500P 2013-12-11 2013-12-11
EP13196737 2013-12-11
PCT/EP2014/076823 WO2015086491A1 (en) 2013-12-11 2014-12-08 Drug delivery system.

Publications (1)

Publication Number Publication Date
MD20160079A2 true MD20160079A2 (ro) 2016-10-31

Family

ID=49759119

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20160079A MD20160079A2 (ro) 2013-12-11 2014-12-08 Sistem de livrare a medicamentului

Country Status (23)

Country Link
US (1) US10413504B2 (ro)
EP (1) EP3079660B1 (ro)
JP (1) JP6251396B2 (ro)
KR (1) KR101808977B1 (ro)
CN (1) CN105979930B (ro)
AP (1) AP2016009223A0 (ro)
AU (1) AU2014363724B2 (ro)
BR (1) BR112016013325B1 (ro)
CA (1) CA2931559C (ro)
CR (1) CR20160261A (ro)
DO (1) DOP2016000132A (ro)
EA (1) EA031802B1 (ro)
HK (1) HK1224208A1 (ro)
IL (1) IL245544A0 (ro)
MA (1) MA39059A1 (ro)
MD (1) MD20160079A2 (ro)
MX (1) MX2016007681A (ro)
PE (1) PE20160680A1 (ro)
PH (1) PH12016501083A1 (ro)
SG (1) SG11201604660VA (ro)
SV (1) SV2016005214A (ro)
TW (1) TW201607563A (ro)
WO (1) WO2015086491A1 (ro)

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US10596103B2 (en) 2013-12-11 2020-03-24 Merek Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
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CN105828791B (zh) 2013-12-19 2019-09-20 宝洁公司 使用碳酸酯使角蛋白纤维成形
CN105828787B (zh) 2013-12-19 2019-07-26 宝洁公司 使用氧代乙酸和/或它们的衍生物使角蛋白纤维成形
MX361102B (es) 2013-12-19 2018-11-27 Procter & Gamble Modelado de fibras de queratina con el uso de un agente activo que comprende al menos dos grupos funcionales seleccionados de: -c(oh)- y -c(=o)oh.
EP3082750A1 (en) 2013-12-19 2016-10-26 The Procter & Gamble Company Shaping keratin fibres using a reducing composition and a fixing composition
EP3082747B1 (en) 2013-12-19 2018-07-04 The Procter and Gamble Company Shaping keratin fibres using a sugar
US11110046B2 (en) 2013-12-19 2021-09-07 The Procter And Gamble Company Shaping keratin fibres using 2-hydroxypropane-1,2,3-tricarboxylic acid and/or 1,2,3,4-butanetetracarboxylic acid
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EP3297731A1 (en) 2014-12-19 2018-03-28 The Procter and Gamble Company Shaping keratin fibres using arabinose and ethylene carbonate
EP3297730A1 (en) 2014-12-19 2018-03-28 The Procter and Gamble Company Method of shaping keratin fibres
EP3310325A1 (en) 2015-06-18 2018-04-25 The Procter and Gamble Company Shaping keratin fibres using dialdehyde compounds
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Also Published As

Publication number Publication date
WO2015086491A1 (en) 2015-06-18
AU2014363724B2 (en) 2017-02-23
CN105979930B (zh) 2019-11-19
AU2014363724A1 (en) 2016-05-26
PE20160680A1 (es) 2016-07-31
CR20160261A (es) 2016-08-16
MX2016007681A (es) 2016-10-14
CA2931559C (en) 2018-03-13
JP6251396B2 (ja) 2017-12-20
EP3079660B1 (en) 2021-03-03
JP2016539991A (ja) 2016-12-22
US20150157561A1 (en) 2015-06-11
SV2016005214A (es) 2016-11-21
CA2931559A1 (en) 2015-06-18
BR112016013325A2 (ro) 2017-08-08
BR112016013325B1 (pt) 2022-11-29
SG11201604660VA (en) 2016-07-28
PH12016501083A1 (en) 2016-07-25
IL245544A0 (en) 2016-06-30
MA39059A1 (fr) 2018-08-31
KR20160095110A (ko) 2016-08-10
EP3079660A1 (en) 2016-10-19
KR101808977B1 (ko) 2017-12-13
TW201607563A (zh) 2016-03-01
AP2016009223A0 (en) 2016-05-31
EA031802B1 (ru) 2019-02-28
EA201691193A1 (ru) 2016-09-30
DOP2016000132A (es) 2016-07-31
US10413504B2 (en) 2019-09-17
CN105979930A (zh) 2016-09-28
HK1224208A1 (zh) 2017-08-18

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Legal Events

Date Code Title Description
FA9A Abandonment or withdrawal of application (patent for invention)