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MA55766A - Nanoparticules lipidiques - Google Patents

Nanoparticules lipidiques

Info

Publication number
MA55766A
MA55766A MA055766A MA55766A MA55766A MA 55766 A MA55766 A MA 55766A MA 055766 A MA055766 A MA 055766A MA 55766 A MA55766 A MA 55766A MA 55766 A MA55766 A MA 55766A
Authority
MA
Morocco
Prior art keywords
lipid nanoparticles
nanoparticles
lipid
Prior art date
Application number
MA055766A
Other languages
English (en)
Inventor
James Heyes
Adam Judge
Kieu Mong Lam
Alan D Martin
Original Assignee
Genevant Sciences Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genevant Sciences Gmbh filed Critical Genevant Sciences Gmbh
Publication of MA55766A publication Critical patent/MA55766A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/5123Organic compounds, e.g. fats, sugars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
MA055766A 2019-04-26 2020-04-24 Nanoparticules lipidiques MA55766A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962839452P 2019-04-26 2019-04-26
US201962867098P 2019-06-26 2019-06-26

Publications (1)

Publication Number Publication Date
MA55766A true MA55766A (fr) 2022-03-02

Family

ID=72941858

Family Applications (1)

Application Number Title Priority Date Filing Date
MA055766A MA55766A (fr) 2019-04-26 2020-04-24 Nanoparticules lipidiques

Country Status (8)

Country Link
US (1) US20220168222A1 (fr)
EP (1) EP3959314A4 (fr)
JP (1) JP2022530018A (fr)
CN (1) CN114026233A (fr)
AU (1) AU2020262437A1 (fr)
CA (1) CA3137450A1 (fr)
MA (1) MA55766A (fr)
WO (1) WO2020219941A1 (fr)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113286622A (zh) * 2018-11-09 2021-08-20 阿布特斯生物制药公司 含硅的阳离子脂质
JP2023507465A (ja) 2019-12-20 2023-02-22 キュアバック エスイー 核酸を送達するための脂質ナノ粒子
US12023376B1 (en) 2020-04-17 2024-07-02 Triad National Security, Llc Conserved region T cell vaccines for coronavirus and methods of use
KR20230038217A (ko) * 2020-07-10 2023-03-17 제네반트 사이언시즈 게엠베하 폐에 치료제를 전달하기 위한 지질 나노입자
KR20230056669A (ko) 2020-07-27 2023-04-27 안자리움 바이오사이언시스 아게 Dna 분자의 조성물, 이의 제조 방법 및 이의 사용 방법
JP2023546175A (ja) 2020-10-14 2023-11-01 ジョージ・メイソン・リサーチ・ファウンデーション・インコーポレイテッド 脂質ナノ粒子製造の方法及びそれに由来する組成物
TW202233232A (zh) 2020-11-06 2022-09-01 法商賽諾菲公司 遞送mRNA疫苗的脂質奈米顆粒
AU2021385572A1 (en) 2020-11-25 2023-06-22 Akagera Medicines, Inc. Lipid nanoparticles for delivery of nucleic acids, and related methods of use
KR20230122081A (ko) * 2020-12-18 2023-08-22 제네반트 사이언시즈 게엠베하 Peg 지질 및 지질 나노입자
EP4308087A4 (fr) * 2021-03-17 2025-06-18 Board of Regents of the University of Nebraska Formulations de nanoparticules lipidiques et leurs méthodes d'utilisation
JP2024516575A (ja) 2021-04-16 2024-04-16 ジェネンテック, インコーポレイテッド 最適化されたtlr7リガンド及びその使用
MX2024002725A (es) 2021-09-03 2024-03-15 CureVac SE Nuevas nanoparticulas lipidicas para la administracion de acidos nucleicos que comprenden fosfatidilserina.
WO2023069948A1 (fr) 2021-10-18 2023-04-27 Flagship Pioneering Innovations Vii, Llc Compositions d'adn et procédés associés
KR20230061895A (ko) * 2021-10-29 2023-05-09 주식회사 아이큐어비앤피 지질 나노입자 및 세포 투과성을 갖는 신규 펩타이드의 복합체
CN119562966A (zh) 2022-05-13 2025-03-04 生物技术公司 靶向hiv的rna组合物
CN117203186A (zh) * 2022-05-13 2023-12-08 南方科技大学 一种含有二硫键的脂质化合物及其组合物
CA3256767A1 (fr) 2022-05-23 2023-11-30 Logicbio Therapeutics, Inc. Compositions de thérapie génique et leurs procédés d'utilisation
US12064479B2 (en) 2022-05-25 2024-08-20 Akagera Medicines, Inc. Lipid nanoparticles for delivery of nucleic acids and methods of use thereof
EP4531905A1 (fr) 2022-05-25 2025-04-09 BioNTech SE Compositions d'arn pour l'administration d'antigènes de la variole du singe et méthodes associées
CN119562807A (zh) 2022-05-30 2025-03-04 生物技术公司 用于递送核酸的复合物
TWI858802B (zh) * 2022-07-06 2024-10-11 南韓商綠十字股份有限公司 使用陽離子膽固醇用於核酸遞送的局部遞送的脂質納米顆粒
KR20250029913A (ko) 2022-07-29 2025-03-05 매사추세츠 인스티튜트 오브 테크놀로지 신호 조절 단백질 알파 (SIRPα) 유전자의 발현을 억제하기 위한 조성물 및 방법
WO2024037577A1 (fr) * 2022-08-18 2024-02-22 Suzhou Abogen Biosciences Co., Ltd. Composition de nanoparticules lipidiques
WO2024057237A1 (fr) 2022-09-16 2024-03-21 Pfizer Inc. Nanoparticules lipidiques
EP4342460A1 (fr) 2022-09-21 2024-03-27 NovoArc GmbH Nanoparticule lipidique avec charge d'acide nucléique
WO2024131810A1 (fr) * 2022-12-21 2024-06-27 Suzhou Abogen Biosciences Co., Ltd. Nanoparticules lipidiques comprenant des phospholipides modifiés par stérol
WO2024141955A1 (fr) 2022-12-28 2024-07-04 BioNTech SE Compositions d'arn ciblant le vih
EP4410316A1 (fr) * 2023-02-01 2024-08-07 4basebio UK Ltd Nanoparticules pour l'administration de charges d'acides nucléiques
WO2024167924A2 (fr) * 2023-02-06 2024-08-15 University Of Tennessee Research Foundation Nanoparticules lipidiques multifonctionnelles et leurs utilisations
WO2024205499A1 (fr) * 2023-03-27 2024-10-03 Agency For Science, Technology And Research Composé pour la préparation de nanoparticules lipidiques encapsulant un agent, composition de nanoparticules comprenant ledit composé et procédés associés
WO2024259158A2 (fr) * 2023-06-13 2024-12-19 Cornell University Nanoparticules lipidiques pour l'administration de peptides et leurs procédés de fabrication et d'utilisation
WO2025027576A2 (fr) 2023-08-03 2025-02-06 BioNTech SE Compositions d'arn ciblant le vih
WO2025027579A2 (fr) 2023-08-03 2025-02-06 BioNTech SE Compositions d'arn ciblant le vih
WO2025046121A1 (fr) 2023-09-01 2025-03-06 Novoarc Gmbh Nanoparticule lipidique avec charge d'acide nucléique et lipide ionisable
WO2025124711A1 (fr) 2023-12-13 2025-06-19 BioNTech SE Compositions de glycolipides
WO2025219570A1 (fr) 2024-04-17 2025-10-23 Johannes Kepler Universität Linz Composition pour inhiber la translocation de protéines et procédés l'utilisant
WO2025242657A1 (fr) 2024-05-21 2025-11-27 Shape Biopharmaceuticals Ag Blocs et agrégats de construction de lipopeptides
GB202408360D0 (en) 2024-06-11 2024-07-24 Cancer Research Tech Ltd Tumour sensitisation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017099823A1 (fr) * 2015-12-10 2017-06-15 Modernatx, Inc. Compositions et procédés permettant d'administrer des agents thérapeutiques
JP7086870B2 (ja) * 2016-06-30 2022-06-20 アルブータス・バイオファーマー・コーポレイション メッセンジャーrnaを送達するための組成物及び方法

Also Published As

Publication number Publication date
JP2022530018A (ja) 2022-06-27
AU2020262437A1 (en) 2021-12-23
CA3137450A1 (fr) 2020-10-29
EP3959314A1 (fr) 2022-03-02
US20220168222A1 (en) 2022-06-02
CN114026233A (zh) 2022-02-08
EP3959314A4 (fr) 2023-02-08
WO2020219941A1 (fr) 2020-10-29

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