MA54567A - Pyridine et composés de pyridimine en tant qu'inhibiteurs de pi3k-gamma - Google Patents
Pyridine et composés de pyridimine en tant qu'inhibiteurs de pi3k-gammaInfo
- Publication number
- MA54567A MA54567A MA054567A MA54567A MA54567A MA 54567 A MA54567 A MA 54567A MA 054567 A MA054567 A MA 054567A MA 54567 A MA54567 A MA 54567A MA 54567 A MA54567 A MA 54567A
- Authority
- MA
- Morocco
- Prior art keywords
- pyridimine
- pi3k
- pyridine
- compounds
- gamma inhibitors
- Prior art date
Links
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 title 2
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662274942P | 2016-01-05 | 2016-01-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA54567A true MA54567A (fr) | 2021-10-27 |
Family
ID=57868380
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA054567A MA54567A (fr) | 2016-01-05 | 2017-01-04 | Pyridine et composés de pyridimine en tant qu'inhibiteurs de pi3k-gamma |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US20170190689A1 (fr) |
| EP (2) | EP3792256B1 (fr) |
| AR (1) | AR107293A1 (fr) |
| ES (2) | ES2995198T3 (fr) |
| MA (1) | MA54567A (fr) |
| TW (1) | TW201734003A (fr) |
| WO (1) | WO2017120194A1 (fr) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9586949B2 (en) | 2015-02-09 | 2017-03-07 | Incyte Corporation | Aza-heteroaryl compounds as PI3K-gamma inhibitors |
| SMT202200250T1 (it) | 2015-11-06 | 2022-07-21 | Incyte Corp | Composti eterociclici come inibitori della pi3k-gamma |
| AR107293A1 (es) | 2016-01-05 | 2018-04-18 | Incyte Corp | COMPUESTOS DE PIRIDINA Y PIRIDIMINA COMO INHIBIDORES DE PI3K-g |
| WO2017223414A1 (fr) | 2016-06-24 | 2017-12-28 | Incyte Corporation | Composants hétérocycliques utilisés en tant qu'inhibiteurs de pi3k-y |
| RS62818B1 (sr) | 2017-10-18 | 2022-02-28 | Incyte Corp | Kondenzovani derivati imidazola zamenjeni tercijarnim hidroksi grupama kao inhibitorima pi3k-gamma |
| US12133852B2 (en) | 2017-11-15 | 2024-11-05 | Epivario, Inc. | ACSS2 inhibitors and methods of use thereof |
| US20210179600A1 (en) * | 2017-11-17 | 2021-06-17 | Hepagene Therapeutics (HK) Limited | Oxazole and thiazole derivatives as inhibitors of ask1 |
| WO2019119206A1 (fr) * | 2017-12-18 | 2019-06-27 | Merck Sharp & Dohme Corp. | Inhibiteurs puriques de la phosphatidylinositol 3-kinase delta humaine |
| SMT202200134T1 (it) | 2018-03-08 | 2022-05-12 | Incyte Corp | Composti di amminopirazindiolo come inibitori di pi3k-y |
| US11046658B2 (en) | 2018-07-02 | 2021-06-29 | Incyte Corporation | Aminopyrazine derivatives as PI3K-γ inhibitors |
| CR20250050A (es) | 2018-09-05 | 2025-03-19 | Incyte Corp | Formas cristalinas de un inhibidor de fosfoinositida 3–quinasa (pi3k) (divisional 2021-0165) |
| EP3952870B1 (fr) * | 2019-04-10 | 2025-09-24 | Nanjing Zenshine Pharmaceuticals Co., Ltd. | Inhibiteur de la phosphatidylinositol 3-kinase |
| US12441689B2 (en) * | 2019-05-14 | 2025-10-14 | Epivario, Inc. | ACSS2 inhibitors and methods of use thereof |
| CN111718310B (zh) * | 2019-08-19 | 2021-06-11 | 中国药科大学 | 苯基取代的五元杂环类化合物及其制备方法、用途和药物组合物 |
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| IL311463A (en) * | 2021-09-14 | 2024-05-01 | Univ Vanderbilt | Heteroaryl-linked analogs as mglu5 negative allosteric modulators and methods of making and using the same |
| WO2023083330A1 (fr) * | 2021-11-12 | 2023-05-19 | 百极优棠(广东)医药科技有限公司 | Inhibiteur de drak2, son procédé de préparation et son utilisation |
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| US9586949B2 (en) | 2015-02-09 | 2017-03-07 | Incyte Corporation | Aza-heteroaryl compounds as PI3K-gamma inhibitors |
| SMT202200250T1 (it) | 2015-11-06 | 2022-07-21 | Incyte Corp | Composti eterociclici come inibitori della pi3k-gamma |
| AR107293A1 (es) | 2016-01-05 | 2018-04-18 | Incyte Corp | COMPUESTOS DE PIRIDINA Y PIRIDIMINA COMO INHIBIDORES DE PI3K-g |
| WO2017223414A1 (fr) | 2016-06-24 | 2017-12-28 | Incyte Corporation | Composants hétérocycliques utilisés en tant qu'inhibiteurs de pi3k-y |
-
2017
- 2017-01-04 AR ARP170100017A patent/AR107293A1/es unknown
- 2017-01-04 US US15/398,121 patent/US20170190689A1/en not_active Abandoned
- 2017-01-04 MA MA054567A patent/MA54567A/fr unknown
- 2017-01-04 WO PCT/US2017/012135 patent/WO2017120194A1/fr not_active Ceased
- 2017-01-04 EP EP20187907.9A patent/EP3792256B1/fr active Active
- 2017-01-04 ES ES20187907T patent/ES2995198T3/es active Active
- 2017-01-04 EP EP17701205.1A patent/EP3400221B1/fr active Active
- 2017-01-04 ES ES17701205T patent/ES2833955T3/es active Active
- 2017-01-04 TW TW106100143A patent/TW201734003A/zh unknown
-
2019
- 2019-03-29 US US16/369,541 patent/US11352340B2/en active Active
-
2022
- 2022-03-25 US US17/705,079 patent/US11952367B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20190359592A1 (en) | 2019-11-28 |
| ES2995198T3 (en) | 2025-02-07 |
| WO2017120194A1 (fr) | 2017-07-13 |
| ES2833955T3 (es) | 2021-06-16 |
| US11952367B2 (en) | 2024-04-09 |
| EP3400221A1 (fr) | 2018-11-14 |
| US11352340B2 (en) | 2022-06-07 |
| US20220227736A1 (en) | 2022-07-21 |
| TW201734003A (zh) | 2017-10-01 |
| US20170190689A1 (en) | 2017-07-06 |
| AR107293A1 (es) | 2018-04-18 |
| EP3400221B1 (fr) | 2020-08-26 |
| EP3792256B1 (fr) | 2024-10-23 |
| EP3792256A1 (fr) | 2021-03-17 |
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