|
US8124A
(en)
|
|
1851-05-27 |
|
mcfarlan |
|
US5730A
(en)
|
|
1848-08-22 |
|
Improvement in steam cotton-presses |
|
US69A
(en)
|
|
1836-10-27 |
|
Machine eor picking or breaking wool and ginned or seedless cotton |
|
US982A
(en)
|
|
1838-10-16 |
|
Stove fob -warming and cooking |
|
US4657760A
(en)
|
1979-03-20 |
1987-04-14 |
Ortho Pharmaceutical Corporation |
Methods and compositions using monoclonal antibody to human T cells
|
|
US4469863A
(en)
|
1980-11-12 |
1984-09-04 |
Ts O Paul O P |
Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5206344A
(en)
|
1985-06-26 |
1993-04-27 |
Cetus Oncology Corporation |
Interleukin-2 muteins and polymer conjugation thereof
|
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
|
GB8601597D0
(en)
|
1986-01-23 |
1986-02-26 |
Wilson R H |
Nucleotide sequences
|
|
US6548640B1
(en)
|
1986-03-27 |
2003-04-15 |
Btg International Limited |
Altered antibodies
|
|
US5567610A
(en)
|
1986-09-04 |
1996-10-22 |
Bioinvent International Ab |
Method of producing human monoclonal antibodies and kit therefor
|
|
ATE108068T1
(de)
|
1987-09-23 |
1994-07-15 |
Bristol Myers Squibb Co |
Antikörper-heterokonjugate zur töting von hiv- infizierten zellen.
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
ES2052027T5
(es)
|
1988-11-11 |
2005-04-16 |
Medical Research Council |
Clonacion de secuencias de dominio variable de inmunoglobulina.
|
|
US5175384A
(en)
|
1988-12-05 |
1992-12-29 |
Genpharm International |
Transgenic mice depleted in mature t-cells and methods for making transgenic mice
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
|
DK0479909T3
(da)
|
1989-06-29 |
1997-04-07 |
Medarex Inc |
Bispecifikke reagenser til AIDS-behandling
|
|
US5225212A
(en)
|
1989-10-20 |
1993-07-06 |
Liposome Technology, Inc. |
Microreservoir liposome composition and method
|
|
US5959177A
(en)
|
1989-10-27 |
1999-09-28 |
The Scripps Research Institute |
Transgenic plants expressing assembled secretory antibodies
|
|
WO1991009058A1
(fr)
|
1989-12-14 |
1991-06-27 |
Sloan-Kettering Institute For Cancer Research |
Emplois therapeutiques de la region hypervariable de l'anticorps monoclonal m195 et de ses structures
|
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
DK0463151T3
(da)
|
1990-01-12 |
1996-07-01 |
Cell Genesys Inc |
Frembringelse af xenogene antistoffer
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5321131A
(en)
|
1990-03-08 |
1994-06-14 |
Hybridon, Inc. |
Site-specific functionalization of oligodeoxynucleotides for non-radioactive labelling
|
|
US5229275A
(en)
|
1990-04-26 |
1993-07-20 |
Akzo N.V. |
In-vitro method for producing antigen-specific human monoclonal antibodies
|
|
JPH06500011A
(ja)
|
1990-06-29 |
1994-01-06 |
ラージ スケール バイオロジー コーポレイション |
形質転換された微生物によるメラニンの製造
|
|
DE69127627T2
(de)
|
1990-08-29 |
1998-02-19 |
Genpharm Int |
Produktion und Nützung nicht-menschliche transgentiere zur Produktion heterologe Antikörper
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
DE69129154T2
(de)
|
1990-12-03 |
1998-08-20 |
Genentech, Inc., South San Francisco, Calif. |
Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften
|
|
US5571894A
(en)
|
1991-02-05 |
1996-11-05 |
Ciba-Geigy Corporation |
Recombinant antibodies specific for a growth factor receptor
|
|
EP0586505A1
(fr)
|
1991-05-14 |
1994-03-16 |
Repligen Corporation |
Anticorps d'heteroconjugues pour le traitement des infections a l'hiv
|
|
DK51092D0
(da)
|
1991-05-24 |
1992-04-15 |
Ole Buchardt |
Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
|
|
US5719262A
(en)
|
1993-11-22 |
1998-02-17 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having amino acid side chains
|
|
DE69233254T2
(de)
|
1991-06-14 |
2004-09-16 |
Genentech, Inc., South San Francisco |
Humanisierter Heregulin Antikörper
|
|
GB9114948D0
(en)
|
1991-07-11 |
1991-08-28 |
Pfizer Ltd |
Process for preparing sertraline intermediates
|
|
JP3951062B2
(ja)
|
1991-09-19 |
2007-08-01 |
ジェネンテック・インコーポレーテッド |
少なくとも遊離のチオールとして存在するシステインを有する抗体フラグメントの大腸菌での発現、2官能性F(ab’)2抗体の産生のための使用
|
|
ES2136092T3
(es)
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
Procedimientos para la produccion de anticuerpos humanizados.
|
|
FI941572A7
(fi)
|
1991-10-07 |
1994-05-27 |
Oncologix Inc |
Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenete lmä
|
|
WO1993008829A1
(fr)
|
1991-11-04 |
1993-05-13 |
The Regents Of The University Of California |
Compositions induisant la destruction de cellules infectees par l'hiv
|
|
WO1993011161A1
(fr)
|
1991-11-25 |
1993-06-10 |
Enzon, Inc. |
Proteines multivalentes de fixation aux antigenes
|
|
CA2103887C
(fr)
|
1991-12-13 |
2005-08-30 |
Gary M. Studnicka |
Methodes et materiaux pour la preparation de domaines variables d'anticorps modifies et leurs utilisations therapeutiques
|
|
US5869619A
(en)
|
1991-12-13 |
1999-02-09 |
Xoma Corporation |
Modified antibody variable domains
|
|
US5700922A
(en)
|
1991-12-24 |
1997-12-23 |
Isis Pharmaceuticals, Inc. |
PNA-DNA-PNA chimeric macromolecules
|
|
DE69334351D1
(de)
|
1992-02-06 |
2011-05-12 |
Novartis Vaccines & Diagnostic |
Biosynthetisches Bindeprotein für Tumormarker
|
|
US5714350A
(en)
|
1992-03-09 |
1998-02-03 |
Protein Design Labs, Inc. |
Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region
|
|
US5573905A
(en)
|
1992-03-30 |
1996-11-12 |
The Scripps Research Institute |
Encoded combinatorial chemical libraries
|
|
ZA932523B
(en)
|
1992-04-10 |
1994-10-08 |
Res Dev Foundation |
Immunotoxins directed against cd33 related surface antigens
|
|
AU678769B2
(en)
|
1992-07-27 |
1997-06-12 |
Hybridon, Inc. |
Oligonucleotide alkylphosphonothioates
|
|
ATE149570T1
(de)
|
1992-08-17 |
1997-03-15 |
Genentech Inc |
Bispezifische immunoadhesine
|
|
FI953510L
(fi)
|
1993-01-21 |
1995-08-24 |
Hybridon Inc |
Laskostuneita, tripleksiä muodostavia oligonukleotideja
|
|
US5637684A
(en)
|
1994-02-23 |
1997-06-10 |
Isis Pharmaceuticals, Inc. |
Phosphoramidate and phosphorothioamidate oligomeric compounds
|
|
US5789199A
(en)
|
1994-11-03 |
1998-08-04 |
Genentech, Inc. |
Process for bacterial production of polypeptides
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
US5840523A
(en)
|
1995-03-01 |
1998-11-24 |
Genetech, Inc. |
Methods and compositions for secretion of heterologous polypeptides
|
|
US5641870A
(en)
|
1995-04-20 |
1997-06-24 |
Genentech, Inc. |
Low pH hydrophobic interaction chromatography for antibody purification
|
|
US5739277A
(en)
|
1995-04-14 |
1998-04-14 |
Genentech Inc. |
Altered polypeptides with increased half-life
|
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
KR100654645B1
(ko)
|
1995-04-27 |
2007-04-04 |
아브게닉스, 인크. |
면역화된 제노마우스 유래의 인간 항체
|
|
AU2466895A
(en)
|
1995-04-28 |
1996-11-18 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6140482A
(en)
|
1995-06-01 |
2000-10-31 |
Hybridon, Inc. |
Primary phosphoramidate internucleoside linkages and oligonucleotides containing the same
|
|
US5955599A
(en)
|
1995-06-01 |
1999-09-21 |
Hybridon, Inc. |
Process for making oligonucleotides containing o- and s- methylphosphotriester internucleoside linkages
|
|
US5962674A
(en)
|
1995-06-01 |
1999-10-05 |
Hybridon, Inc. |
Synthesis of oligonucleotides containing alkylphosphonate internucleoside linkages
|
|
US5614622A
(en)
|
1995-06-01 |
1997-03-25 |
Hybridon, Inc. |
5-pentenoyl moiety as a nucleoside-amino protecting group, 4-pentenoyl-protected nucleotide synthons, and related oligonucleotide syntheses
|
|
US5637683A
(en)
|
1995-07-13 |
1997-06-10 |
Cornell Research Foundation, Inc. |
Nucleic acid analog with amide linkage and method of making that analog
|
|
US5652356A
(en)
|
1995-08-17 |
1997-07-29 |
Hybridon, Inc. |
Inverted chimeric and hybrid oligonucleotides
|
|
JP2002514895A
(ja)
|
1995-09-28 |
2002-05-21 |
アレクション、ファーマスーティカルズ、インコーポレーテッド |
ブタ細胞相互作用タンパク質
|
|
DE19544393A1
(de)
|
1995-11-15 |
1997-05-22 |
Hoechst Schering Agrevo Gmbh |
Synergistische herbizide Mischungen
|
|
AU4089397A
(en)
|
1996-08-26 |
1998-03-19 |
Hybridon, Inc. |
Improved reagents and process for synthesis of oligonucleotides containing phosphorodithioate internucleoside linkages
|
|
US5886165A
(en)
|
1996-09-24 |
1999-03-23 |
Hybridon, Inc. |
Mixed backbone antisense oligonucleotides containing 2'-5'-ribonucleotide- and 3'-5'-deoxyribonucleotides segments
|
|
JP4215172B2
(ja)
|
1996-12-03 |
2009-01-28 |
アムジェン フレモント インク. |
複数のV▲下H▼およびV▲下κ▼領域を含むヒトIg遺伝子座を有するトランスジェニック哺乳動物、ならびにそれから産生される抗体
|
|
US5739314A
(en)
|
1997-04-25 |
1998-04-14 |
Hybridon, Inc. |
Method for synthesizing 2'-O-substituted pyrimidine nucleosides
|
|
US6040498A
(en)
|
1998-08-11 |
2000-03-21 |
North Caroline State University |
Genetically engineered duckweed
|
|
US6610833B1
(en)
|
1997-11-24 |
2003-08-26 |
The Institute For Human Genetics And Biochemistry |
Monoclonal human natural antibodies
|
|
ATE531812T1
(de)
|
1997-12-05 |
2011-11-15 |
Scripps Research Inst |
Humanisierung von nager-antikörpern
|
|
US6506559B1
(en)
|
1997-12-23 |
2003-01-14 |
Carnegie Institute Of Washington |
Genetic inhibition by double-stranded RNA
|
|
GB9809951D0
(en)
|
1998-05-08 |
1998-07-08 |
Univ Cambridge Tech |
Binding molecules
|
|
DE19956568A1
(de)
|
1999-01-30 |
2000-08-17 |
Roland Kreutzer |
Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens
|
|
DE60029314T2
(de)
|
1999-03-24 |
2007-07-12 |
Exiqon A/S |
Verbesserte Synthese für -2.2.1. I Bicyclo-Nukleoside
|
|
KR20010001577A
(ko)
|
1999-06-07 |
2001-01-05 |
윤종용 |
고분자 광산발생제를 이용한 올리고펩티드 핵산 탐침의 제조방법
|
|
AU6629200A
(en)
|
1999-08-25 |
2001-03-19 |
Philip P Garner |
Alpha-helical peptide nucleic acid alpha-pna
|
|
US7125978B1
(en)
|
1999-10-04 |
2006-10-24 |
Medicago Inc. |
Promoter for regulating expression of foreign genes
|
|
DE60022369T2
(de)
|
1999-10-04 |
2006-05-18 |
Medicago Inc., Sainte Foy |
Verfahren zur regulation der transkription von fremden genen in gegenwart von stickstoff
|
|
EP1235842A4
(fr)
|
1999-10-15 |
2003-04-23 |
Univ Massachusetts |
Genes de voies d'interference d'arn en tant qu'outils d'interference genetique ciblee
|
|
GB9927444D0
(en)
|
1999-11-19 |
2000-01-19 |
Cancer Res Campaign Tech |
Inhibiting gene expression
|
|
US6596541B2
(en)
|
2000-10-31 |
2003-07-22 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
IL155977A0
(en)
|
2000-11-30 |
2003-12-23 |
Medarex Inc |
Transgenic transchromosomal rodents for making human antibodies
|
|
US6455308B1
(en)
|
2001-08-01 |
2002-09-24 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of serum amyloid A4 expression
|
|
EP2131198B1
(fr)
|
2001-09-20 |
2013-03-27 |
Board of Regents, The University of Texas System |
Mesure des anticorps thérapeutiques, des antigènes et des complexes antigène/anticorps circulants à l'aide d'analyse ELISA
|
|
US20030206916A1
(en)
|
2002-05-03 |
2003-11-06 |
Rush-Presbyterian-St. Luke's Medical Center |
Immunogenic peptides
|
|
EP1556684A4
(fr)
|
2002-11-01 |
2008-01-23 |
Univ Colorado Regents |
Analyse quantitative d'isoformes de proteines utilisant la spectrometrie de masse a temps de vol par desorption/ionisation laser assistee par matrice
|
|
MXPA05004712A
(es)
|
2002-11-07 |
2005-11-23 |
Immunogen Inc |
Anticuerpos anti-cd33 y metodo para tratamiento de leucemia mieloide aguda utilizando los mismos.
|
|
MXPA06011199A
(es)
|
2004-03-31 |
2007-04-16 |
Genentech Inc |
Anticuerpos anti-tgf-beta humanizados.
|
|
EP1838735A2
(fr)
|
2004-12-31 |
2007-10-03 |
Genentech, Inc. |
Polypeptides de liaison a la br3 et leurs utilisations
|
|
EP2361933A3
(fr)
|
2005-01-26 |
2012-05-02 |
Amgen Fremont Inc. |
Anticorps contre l'interleukine-1 bêta
|
|
US7700099B2
(en)
|
2005-02-14 |
2010-04-20 |
Merck & Co., Inc. |
Non-immunostimulatory antibody and compositions containing the same
|
|
TW200726776A
(en)
|
2005-07-29 |
2007-07-16 |
Friedrich Alexander University Of Erlangen Nuremberg |
CD33-specific single-chain immunotoxin and methods of use
|
|
US7420041B2
(en)
|
2006-02-24 |
2008-09-02 |
Arius Research Inc. |
Cytotoxicity mediation of cells evidencing surface expression of TROP-2
|
|
BRPI0708909B8
(pt)
|
2006-03-15 |
2021-05-25 |
Alexion Pharma Inc |
uso de um anticorpo que se liga a c5 para tratar um paciente que sofre de hemoglobinúria paroxística noturna
|
|
EP2016101A2
(fr)
|
2006-05-09 |
2009-01-21 |
Genentech, Inc. |
Polypeptides de liaison à squelettes optimisés
|
|
CA2667808A1
(fr)
|
2006-11-02 |
2008-05-15 |
Seattle Genetics, Inc. |
Methodes pour traiter des maladies neoplasiques, auto-immunes, et inflammatoires
|
|
UY30776A1
(es)
|
2006-12-21 |
2008-07-03 |
Medarex Inc |
Anticuerpos cd44
|
|
CN100592373C
(zh)
|
2007-05-25 |
2010-02-24 |
群康科技(深圳)有限公司 |
液晶显示面板驱动装置及其驱动方法
|
|
US8877688B2
(en)
|
2007-09-14 |
2014-11-04 |
Adimab, Llc |
Rationally designed, synthetic antibody libraries and uses therefor
|
|
CA3187687A1
(fr)
|
2007-09-14 |
2009-03-19 |
Adimab, Llc |
Bibliotheques d'anticorps synthetiques rationnelles et leurs utilisations
|
|
FR2945538B1
(fr)
|
2009-05-12 |
2014-12-26 |
Sanofi Aventis |
Anticorps humanises specifiques de la forme protofibrillaire du peptide beta-amyloide.
|
|
DE102009045006A1
(de)
|
2009-09-25 |
2011-04-14 |
Technische Universität Dresden |
Anti-CD33 Antikörper und ihre Anwendung zum Immunotargeting bei der Behandlung von CD33-assoziierten Erkrankungen
|
|
AU2010298036B2
(en)
|
2009-09-25 |
2015-05-21 |
Xoma Technology Ltd. |
Screening methods
|
|
KR102318383B1
(ko)
|
2010-07-16 |
2021-10-27 |
아디맵 엘엘씨 |
항체 라이브러리
|
|
UA112062C2
(uk)
|
2010-10-04 |
2016-07-25 |
Бьорінгер Інгельхайм Інтернаціональ Гмбх |
Cd33-зв'язувальний агент
|
|
WO2012074097A1
(fr)
|
2010-12-03 |
2012-06-07 |
協和発酵キリン株式会社 |
Anticorps anti-cd33
|
|
US20130309223A1
(en)
|
2012-05-18 |
2013-11-21 |
Seattle Genetics, Inc. |
CD33 Antibodies And Use Of Same To Treat Cancer
|
|
CN102952191B
(zh)
|
2012-09-17 |
2014-05-14 |
浙江大学 |
全人源抗cd33单链抗体zjl101及其应用
|
|
WO2014160871A2
(fr)
|
2013-03-27 |
2014-10-02 |
The General Hospital Corporation |
Procédés et agents pour le traitement de la maladie d'alzheimer
|
|
PE20160712A1
(es)
|
2013-12-13 |
2016-07-26 |
Genentech Inc |
Anticuerpos e inmunoconjugados anti-cd33
|
|
AR101669A1
(es)
|
2014-07-31 |
2017-01-04 |
Amgen Res Munich Gmbh |
Constructos de anticuerpos para cdh19 y cd3
|
|
JPWO2016052756A1
(ja)
*
|
2014-10-01 |
2017-08-03 |
株式会社オーダーメードメディカルリサーチ |
浸潤能の高い癌細胞の検出用又は診断用試薬
|
|
US10501555B2
(en)
|
2014-12-04 |
2019-12-10 |
Abruzzo Theranostic S.R.L. |
Humanized anti-trop-2 monoclonal antibodies and uses thereof
|
|
CN116063499A
(zh)
|
2015-06-12 |
2023-05-05 |
艾利妥 |
抗cd33抗体及其使用方法
|
|
EP3307779A2
(fr)
|
2015-06-12 |
2018-04-18 |
Alector LLC |
Anticorps anti-cd33 et leurs procédés d'utilisation
|
|
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(ko)
|
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|
|
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(ar)
|
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Janssen Biotech Inc |
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|
|
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(hr)
|
2018-08-31 |
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|
|
US12247073B2
(en)
|
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Alector Llc |
Anti-CD33 antibodies and methods of use thereof
|
|
EP4073119A1
(fr)
|
2019-12-12 |
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Alector LLC |
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|