MA50496A - Compositions d'insuline à action rapide - Google Patents

Compositions d'insuline à action rapide

Info

Publication number: MA50496A
Authority: MA; Morocco
Prior art keywords: fast; acting insulin; insulin compositions; compositions; acting
Prior art date: 2017-06-01

Application number

MA050496A

Other languages

English (en)

Inventor

Chad Donald Paavola

Jun Zhang

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2017-06-01

Filing date

2018-05-31

Publication date

2020-09-09

2018-05-31 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2020-09-09 Publication of MA50496A publication Critical patent/MA50496A/fr

Links

NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 2
102000004877 Insulin Human genes 0.000 title 1
108090001061 Insulin Proteins 0.000 title 1
229940125396 insulin Drugs 0.000 title 1
239000000203 mixture Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Epidemiology (AREA)
Diabetes (AREA)
Engineering & Computer Science (AREA)
Inorganic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Endocrinology (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Zoology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Dermatology (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Obesity (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

MA050496A 2017-06-01 2018-05-31 Compositions d'insuline à action rapide MA50496A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US201762513645P	2017-06-01	2017-06-01

Publications (1)

Publication Number	Publication Date
MA50496A true MA50496A (fr)	2020-09-09

Family

ID=62779004

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA050496A MA50496A (fr)	2017-06-01	2018-05-31	Compositions d'insuline à action rapide

Country Status (25)

Country	Link
US (1)	US11207384B2 (fr)
EP (1)	EP3630166B1 (fr)
JP (1)	JP6920471B2 (fr)
KR (2)	KR20190140048A (fr)
CN (1)	CN110662551B (fr)
AU (1)	AU2018275545B2 (fr)
BR (1)	BR112019022212A2 (fr)
CA (1)	CA3065308C (fr)
CL (1)	CL2019003336A1 (fr)
CO (1)	CO2019013251A2 (fr)
CR (1)	CR20190522A (fr)
DO (1)	DOP2019000300A (fr)
EA (1)	EA201992351A1 (fr)
EC (1)	ECSP19085451A (fr)
ES (1)	ES2912162T3 (fr)
IL (1)	IL270975B2 (fr)
JO (1)	JOP20190277B1 (fr)
MA (1)	MA50496A (fr)
MX (1)	MX2019014195A (fr)
NZ (1)	NZ758298A (fr)
PE (1)	PE20200017A1 (fr)
PH (1)	PH12019502677A1 (fr)
SA (1)	SA519410672B1 (fr)
UA (1)	UA126450C2 (fr)
WO (1)	WO2018222787A1 (fr)

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0018609B1 (fr)	1979-04-30	1983-09-21	Hoechst Aktiengesellschaft	Solutions aqueuses de protéines, stables à la dénaturation, procédé pour leur fabrication et leur utilisation
FI78616C (fi)	1982-02-05	1989-09-11	Novo Industri As	Foerfarande foer framstaellning av en foer infusionsaendamaol avsedd stabiliserad insulinloesning, som har en foerhoejd zinkhalt.
PH25772A (en)	1985-08-30	1991-10-18	Novo Industri As	Insulin analogues, process for their preparation
NZ223630A (en)	1987-02-25	1989-11-28	Novo Industri As	Insulin derivative and pharmaceutical compositions
JPH04502465A (ja)	1988-12-23	1992-05-07	ノボ　ノルディスク　アクティーゼルスカブ	ヒトインシュリン類似物質
US5716927A (en)	1988-12-23	1998-02-10	Novo Nordisk A/S	Insulin analogs having a modified B-chain
US5547942A (en)	1994-01-04	1996-08-20	Rapaport; Eliezer	Method of treatment of diabetes mellitus by administration of adenosine 5'-t
US5474978A (en)	1994-06-16	1995-12-12	Eli Lilly And Company	Insulin analog formulations
US5912014A (en)	1996-03-15	1999-06-15	Unigene Laboratories, Inc.	Oral salmon calcitonin pharmaceutical products
US5866538A (en)	1996-06-20	1999-02-02	Novo Nordisk A/S	Insulin preparations containing NaCl
AUPO066096A0 (en)	1996-06-26	1996-07-18	Peptide Delivery Systems Pty Ltd	Oral delivery of peptides
AU1870099A (en)	1998-01-09	1999-07-26	Novo Nordisk A/S	Stabilised insulin compositions
WO2000043034A2 (fr)	1999-01-26	2000-07-27	Eli Lilly And Company	Formulations d'analogues d'insuline acyles hexameres monodisperses
AU779798C (en)	1999-11-15	2005-11-17	Hanamaraddi T. Gangal	Dextrose and insulin fluid formulation for intravenous infusion
US7084126B1 (en)	2000-05-01	2006-08-01	Healthpartners Research Foundation	Methods and compositions for enhancing cellular function through protection of tissue components
US20020141946A1 (en)	2000-12-29	2002-10-03	Advanced Inhalation Research, Inc.	Particles for inhalation having rapid release properties
DE10114178A1 (de)	2001-03-23	2002-10-10	Aventis Pharma Gmbh	Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
DE10227232A1 (de)	2002-06-18	2004-01-15	Aventis Pharma Deutschland Gmbh	Saure Insulinzubereitungen mit verbesserter Stabilität
DE10351594A1 (de) *	2003-11-05	2005-06-16	Tecpharma Licensing Ag	Vorrichtung für die Verabreichung eines injizierbaren Produkts
US20080090753A1 (en)	2004-03-12	2008-04-17	Biodel, Inc.	Rapid Acting Injectable Insulin Compositions
US7279457B2 (en)	2004-03-12	2007-10-09	Biodel, Inc.	Rapid acting drug delivery compositions
US20070086952A1 (en)	2005-09-29	2007-04-19	Biodel, Inc.	Rapid Acting and Prolonged Acting Inhalable Insulin Preparations
US8084420B2 (en)	2005-09-29	2011-12-27	Biodel Inc.	Rapid acting and long acting insulin combination formulations
AU2008259768B2 (en)	2007-06-05	2013-08-29	Paka Pulmonary Pharmaceuticals, Inc.	Compositions for delivering medicaments into the lungs, uses thereof
ES2744384T3 (es)	2007-06-13	2020-02-24	Novo Nordisk As	Formulación farmacéutica que comprende un derivado de insulina
TWI394580B (zh)	2008-04-28	2013-05-01	Halozyme Inc	超快起作用胰島素組成物
US9060927B2 (en)	2009-03-03	2015-06-23	Biodel Inc.	Insulin formulations for rapid uptake
US20120094902A1 (en)	2009-03-27	2012-04-19	Adocia	Fast-acting insulin formulation
FR2943538B1 (fr)	2009-03-27	2011-05-20	Adocia	Formulation a action rapide d'insuline recombinante humaine
EP2590667A4 (fr)	2010-07-07	2013-11-27	Biodel Inc	Compositions et procédés pour la modulation de la pharmacocinétique et de la pharmacodynamie de l'insuline
EP2720713A2 (fr)	2011-06-17	2014-04-23	Halozyme, Inc.	Procédés de perfusion d'insuline sous-cutanée continue utilisant une enzyme de dégradation de l'hyaluronane
US9993529B2 (en)	2011-06-17	2018-06-12	Halozyme, Inc.	Stable formulations of a hyaluronan-degrading enzyme
US20130231281A1 (en)	2011-11-02	2013-09-05	Adocia	Rapid acting insulin formulation comprising an oligosaccharide
LT3130347T (lt)	2011-12-30	2019-10-25	Halozyme Inc	Ph20 polipeptido variantai, kompozicijos ir jų panaudojimas
US9381247B2 (en)	2012-04-16	2016-07-05	Biodel Inc.	Magnesium compositions for modulating the pharmacokinetics and pharmacodynamics of insulin and insulin analogs, and injection site pain
US9399065B2 (en)	2012-04-16	2016-07-26	Biodel Inc.	Magnesium compositions for modulating the pharmacokinetics and injection site pain of insulin
MX360107B (es)	2012-11-13	2018-10-23	Adocia	Formulación de acción rápida de insulina que comprende un compuesto aniónico sustituido.
US20150065423A1 (en)	2013-08-30	2015-03-05	Perosphere, Inc.	Rapid acting injectable formulations
CA2936563A1 (fr)	2014-01-13	2015-07-16	Thermalin Diabetes, Llc	Formulations d'insuline a action rapide et systemes d'administration pharmaceutique
US20150273022A1 (en)	2014-02-10	2015-10-01	Biodel Inc.	Stabilized ultra-rapid-acting insulin formulations
TWI685348B (zh)	2014-05-08	2020-02-21	美國禮來大藥廠	速效胰島素組合物
US9795678B2 (en) *	2014-05-14	2017-10-24	Adocia	Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound
TW201630622A (zh) *	2014-12-16	2016-09-01	美國禮來大藥廠	速效胰島素組合物
EP3328388B1 (fr)	2015-07-28	2023-12-27	Eli Lilly and Company	Préparation pharmaceutique pour améliorer l'absorption et l'action hypoglycémique postprandiale de l'insuline
JO3749B1 (ar) *	2015-08-27	2021-01-31	Lilly Co Eli	تركيبات إنسولين سريعة المفعول
GB201607918D0 (en) *	2016-05-06	2016-06-22	Arecor Ltd	Novel formulations
US11247996B2 (en)	2016-07-29	2022-02-15	University Of Massachusetts	Small molecule inhibitors for transcription factors
GB201707189D0 (en)	2017-05-05	2017-06-21	Arecor Ltd	Novel formulations
GB201707188D0 (en)	2017-05-05	2017-06-21	Arecor Ltd	Novel formulations

2018
- 2018-05-31 MA MA050496A patent/MA50496A/fr unknown
- 2018-05-31 US US16/615,894 patent/US11207384B2/en active Active
- 2018-05-31 KR KR1020197035033A patent/KR20190140048A/ko active Application Filing
- 2018-05-31 CR CR20190522A patent/CR20190522A/es unknown
- 2018-05-31 NZ NZ758298A patent/NZ758298A/en not_active IP Right Cessation
- 2018-05-31 UA UAA201911304A patent/UA126450C2/uk unknown
- 2018-05-31 KR KR1020217026363A patent/KR102342865B1/ko active Active
- 2018-05-31 BR BR112019022212-0A patent/BR112019022212A2/pt unknown
- 2018-05-31 JP JP2019564109A patent/JP6920471B2/ja active Active
- 2018-05-31 CN CN201880035963.1A patent/CN110662551B/zh active Active
- 2018-05-31 PE PE2019002463A patent/PE20200017A1/es unknown
- 2018-05-31 AU AU2018275545A patent/AU2018275545B2/en active Active
- 2018-05-31 ES ES18735017T patent/ES2912162T3/es active Active
- 2018-05-31 JO JOP/2019/0277A patent/JOP20190277B1/ar active
- 2018-05-31 MX MX2019014195A patent/MX2019014195A/es unknown
- 2018-05-31 EA EA201992351A patent/EA201992351A1/ru unknown
- 2018-05-31 WO PCT/US2018/035261 patent/WO2018222787A1/fr active Application Filing
- 2018-05-31 CA CA3065308A patent/CA3065308C/fr active Active
- 2018-05-31 IL IL270975A patent/IL270975B2/en unknown
- 2018-05-31 EP EP18735017.8A patent/EP3630166B1/fr active Active
2019
- 2019-11-20 CL CL2019003336A patent/CL2019003336A1/es unknown
- 2019-11-26 CO CONC2019/0013251A patent/CO2019013251A2/es unknown
- 2019-11-27 PH PH12019502677A patent/PH12019502677A1/en unknown
- 2019-11-28 SA SA519410672A patent/SA519410672B1/ar unknown
- 2019-11-29 DO DO2019000300A patent/DOP2019000300A/es unknown
- 2019-11-29 EC ECSENADI201985451A patent/ECSP19085451A/es unknown

Also Published As

Publication number	Publication date
PE20200017A1 (es)	2020-01-06
UA126450C2 (uk)	2022-10-05
JOP20190277B1 (ar)	2023-09-17
CR20190522A (es)	2020-01-15
JP6920471B2 (ja)	2021-08-18
EP3630166A1 (fr)	2020-04-08
BR112019022212A2 (pt)	2020-05-12
US11207384B2 (en)	2021-12-28
EP3630166B1 (fr)	2022-04-06
KR102342865B1 (ko)	2021-12-24
CO2019013251A2 (es)	2020-01-17
IL270975B2 (en)	2024-02-01
DOP2019000300A (es)	2019-01-15
CN110662551A (zh)	2020-01-07
PH12019502677A1 (en)	2020-06-08
KR20190140048A (ko)	2019-12-18
ES2912162T3 (es)	2022-05-24
MX2019014195A (es)	2020-01-27
IL270975A (en)	2020-01-30
CA3065308C (fr)	2022-05-17
JP2020522470A (ja)	2020-07-30
CN110662551B (zh)	2023-07-18
CL2019003336A1 (es)	2020-05-15
AU2018275545A1 (en)	2019-10-31
AU2018275545B2 (en)	2021-02-04
US20200078446A1 (en)	2020-03-12
WO2018222787A1 (fr)	2018-12-06
IL270975B1 (en)	2023-10-01
CA3065308A1 (fr)	2018-12-06
ECSP19085451A (es)	2019-12-27
EA201992351A1 (ru)	2020-03-26
JOP20190277A1 (ar)	2019-11-28
SA519410672B1 (ar)	2022-06-16
KR20210106029A (ko)	2021-08-27
NZ758298A (en)	2022-11-25

Publication	Publication Date	Title
MA42701A (fr)	2018-07-04	Compositions d'insuline à action rapide
MA41188A (fr)	2017-10-24	Compositions d'insuline à action rapide
MA42036A (fr)	2018-03-14	Analogues nucléosidiques 5'-substitués
EP4086278A4 (fr)	2024-08-07	Dérivé d'insuline
EP3618840C0 (fr)	2023-12-27	Formulations d'insuline stables
EP3661997A4 (fr)	2021-06-16	Compositions durcissables à l'humidité
EP3720268A4 (fr)	2021-08-25	Cultivar de stévia '16228013'
EP3363581A4 (fr)	2019-05-22	Composition d'assemblage
MA45727A (fr)	2019-05-29	Analogues de l'insuline
MA50496A (fr)	2020-09-09	Compositions d'insuline à action rapide
UA40055S (uk)	2019-09-10	Логотип «е»
UA39565S (uk)	2019-06-25	Логотип «zaryad»
UA38681S (uk)	2019-02-11	Логотип «ventus 95»
UA38759S (uk)	2019-02-25	Логотип «совеня будік»
UA39088S (uk)	2019-04-25	Логотип «mirka»
UA37581S (uk)	2018-08-27	Логотип «buhiv»
UA37572S (uk)	2018-08-27	Логотип «кофито»
UA39072S (uk)	2019-04-25	Логотип «vігop»
UA35221S (uk)	2017-08-28	Диван «gretta»
UA37511S (uk)	2018-08-27	Логотип «meiwei»
UA36616S (uk)	2018-04-10	Логотип «karpatika»
UA37050S (uk)	2018-06-11	Логотип «колос ковалівка»
UA37049S (uk)	2018-06-11	Логотип «agroportex»
UA35335S (uk)	2017-09-11	Гойдалка-каталка «пес»
UA35334S (uk)	2017-09-11	Гойдалка-каталка «коник»