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MA28363A1 - Antagonistes des recepteurs muscariniques de l'acetylcholine - Google Patents

Antagonistes des recepteurs muscariniques de l'acetylcholine

Info

Publication number
MA28363A1
MA28363A1 MA29273A MA29273A MA28363A1 MA 28363 A1 MA28363 A1 MA 28363A1 MA 29273 A MA29273 A MA 29273A MA 29273 A MA29273 A MA 29273A MA 28363 A1 MA28363 A1 MA 28363A1
Authority
MA
Morocco
Prior art keywords
antagonists
acetylcholine receptors
muscarinic acetylcholine
muscarinic
receptors
Prior art date
Application number
MA29273A
Other languages
English (en)
Inventor
Dramane I Laine
Michael R Palovich
Alexander G Preston
Anthony William James Cooper
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of MA28363A1 publication Critical patent/MA28363A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA29273A 2004-01-13 2006-08-15 Antagonistes des recepteurs muscariniques de l'acetylcholine MA28363A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53609204P 2004-01-13 2004-01-13

Publications (1)

Publication Number Publication Date
MA28363A1 true MA28363A1 (fr) 2006-12-01

Family

ID=34794385

Family Applications (1)

Application Number Title Priority Date Filing Date
MA29273A MA28363A1 (fr) 2004-01-13 2006-08-15 Antagonistes des recepteurs muscariniques de l'acetylcholine

Country Status (16)

Country Link
US (1) US20080249127A1 (fr)
EP (1) EP1711183A4 (fr)
JP (1) JP2007518740A (fr)
KR (1) KR20060129017A (fr)
CN (1) CN1929844A (fr)
AR (1) AR049464A1 (fr)
AU (1) AU2005204935A1 (fr)
BR (1) BRPI0506777A (fr)
CA (1) CA2552880A1 (fr)
IL (1) IL176775A0 (fr)
MA (1) MA28363A1 (fr)
NO (1) NO20063636L (fr)
PE (1) PE20050898A1 (fr)
RU (1) RU2006129289A (fr)
TW (1) TW200534855A (fr)
WO (1) WO2005067537A2 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007528420A (ja) * 2004-03-11 2007-10-11 グラクソ グループ リミテッド 新規m3ムスカリン性アセチルコリン受容体アンタゴニスト
TWI363759B (en) 2004-04-27 2012-05-11 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
EP1747219A4 (fr) * 2004-05-13 2010-05-26 Glaxo Group Ltd Domaine de l'invention antagonistes récepteurs d'acétyle choline muscarinique
JP2008505118A (ja) * 2004-06-30 2008-02-21 グラクソ グループ リミテッド ムスカリン性アセチルコリン受容体アンタゴニスト
US7932247B2 (en) * 2004-11-15 2011-04-26 Glaxo Group Limited M3 muscarinic acetylcholine receptor antagonists
EP1856049A1 (fr) 2005-03-10 2007-11-21 Theravance, Inc. Composes biphenyles utiles en tant qu'antagonistes des recepteurs muscariniques
EP1904446A2 (fr) * 2005-07-11 2008-04-02 Ranbaxy Laboratories Limited Antagonistes des recepteurs muscariniques
UY31637A1 (es) 2008-02-06 2009-08-03 Farmacoforos duales-antagonistas muscarinicos de pde4
PE20091563A1 (es) 2008-02-06 2009-11-05 Glaxo Group Ltd Farmacoforos duales - antagonistas muscarinicos de pde4
CL2009000248A1 (es) 2008-02-06 2009-09-11 Glaxo Group Ltd Compuestos derivados de pirazolo [3,4-b] piridin-5-il, inhibidores de la fosfodiesterasa de tipo iv (pde4) y antagonista de receptores muscarinicos de acetilcolina (machr); composicion farmaceutica que los comprende; y su uso en la preparacion de medicamentos utiles en el tratamiento de enferemedades respiratorias y alergicas
WO2010094643A1 (fr) 2009-02-17 2010-08-26 Glaxo Group Limited Dérivés de quinoline et applications associées dans la rhinite et l'urticaire
BRPI1014390A2 (pt) 2009-04-30 2016-04-05 Teijin Pharma Ltd composto de sal de amônio quaternário, composição medicinal, e, agente preventivo ou terapêutico
WO2014023325A1 (fr) * 2012-08-06 2014-02-13 Fondazione Istituto Italiano Di Tecnologia Inhibiteurs de faah et de cox multicibles et leurs utilisations thérapeutiques
KR101538846B1 (ko) * 2013-07-30 2015-07-22 동아에스티 주식회사 신규한 바이페닐 유도체 및 그의 제조방법
KR102239776B1 (ko) * 2016-08-26 2021-04-13 동아에스티 주식회사 (r)-(1-메틸피롤리딘-3-일)메틸(3'-클로로-4'-플루오로-[1,1'-비페닐]-2-일)카바메이트의 신규염 및 이의 결정형
PH12019500380B1 (en) * 2016-08-26 2024-04-17 Dong A St Co Ltd Novel salt of (r)-(1-methylpyrrolidine-3-yl)methyl(3`-chloro-4`fluoro-[1,1`-biphenyl]-2-yl)carbamate and a crystal form thereof
EP3710483A4 (fr) 2017-11-16 2021-10-20 XL-protein GmbH Protéines de fusion vegfr/pdgfr pasylées et leur utilisation en thérapie
JP2021505569A (ja) * 2017-12-04 2021-02-18 フリードリヒ−アレクサンダー−ウニヴェルシテート エアランゲン−ニュルンベルク M2よりもm3に対して選択性を有するフルオロフェニル置換ムスカリン受容体リガンド

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1140998B (it) * 1980-06-18 1986-10-10 Valeas Ind Chimica E Farmaceut Sali di endo-8-metil-8-sin-alchil-8-azoniabiciclo aperta par. quadrata 3.2.1. chiusa par. quadrata-ottan-3-alchilcarbossilati, processo per la loro preparazione e composizioni terapeutiche che li contengono come principio attivo
WO1995021820A1 (fr) * 1994-02-10 1995-08-17 Yamanouchi Pharmaceutical Co., Ltd. Nouveau derive du carbamate et composition correspondante
AU2001271027B2 (en) * 2000-07-11 2005-07-07 Msd K.K. Ester derivatives
US7365167B2 (en) * 2001-11-26 2008-04-29 Cell Matrix, Inc. Humanized collagen antibodies and related methods
WO2003094831A2 (fr) * 2002-05-07 2003-11-20 Neurosearch A/S Nouveaux derives de biaryle diazabicyclique
US7041674B2 (en) * 2002-11-26 2006-05-09 Boehringer Ingelhiem Pharma Gmbh & Co. Kg Carbamic acid esters with anticholinergic activity
DE10255040A1 (de) * 2002-11-26 2004-06-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Carbaminsäureester mit anticholinerger Wirksamkeit
EP1613307A4 (fr) * 2003-04-07 2008-03-12 Glaxo Group Ltd Antagonistes du recepteur muscarinique m sb 3 /sb de l'acetylcholine

Also Published As

Publication number Publication date
PE20050898A1 (es) 2005-11-06
KR20060129017A (ko) 2006-12-14
RU2006129289A (ru) 2008-02-20
WO2005067537A3 (fr) 2006-05-18
JP2007518740A (ja) 2007-07-12
TW200534855A (en) 2005-11-01
CA2552880A1 (fr) 2005-07-28
EP1711183A2 (fr) 2006-10-18
CN1929844A (zh) 2007-03-14
AU2005204935A1 (en) 2005-07-28
NO20063636L (no) 2006-10-04
BRPI0506777A (pt) 2007-05-22
IL176775A0 (en) 2006-10-31
AR049464A1 (es) 2006-08-09
EP1711183A4 (fr) 2009-04-01
WO2005067537A2 (fr) 2005-07-28
US20080249127A1 (en) 2008-10-09

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