MA28348A1 - Pipéridinylcarbonyl-pyrrolidines et leur utilisation comme agonistes de mélanocortine - Google Patents
Pipéridinylcarbonyl-pyrrolidines et leur utilisation comme agonistes de mélanocortineInfo
- Publication number
- MA28348A1 MA28348A1 MA29242A MA29242A MA28348A1 MA 28348 A1 MA28348 A1 MA 28348A1 MA 29242 A MA29242 A MA 29242A MA 29242 A MA29242 A MA 29242A MA 28348 A1 MA28348 A1 MA 28348A1
- Authority
- MA
- Morocco
- Prior art keywords
- piperidinylcarbonyl
- pyrrolidines
- melanocortin agonists
- melanocortin
- agonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Gynecology & Obstetrics (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Cardiology (AREA)
- Pregnancy & Childbirth (AREA)
- Child & Adolescent Psychology (AREA)
- Anesthesiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0402492.3A GB0402492D0 (en) | 2004-02-04 | 2004-02-04 | Pharmaceutically active compounds |
GB0412417A GB0412417D0 (en) | 2004-06-03 | 2004-06-03 | Pharmaceutically active compounds |
GB0425530A GB0425530D0 (en) | 2004-11-19 | 2004-11-19 | Pharmaceutically active compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
MA28348A1 true MA28348A1 (fr) | 2006-12-01 |
Family
ID=34864830
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA29242A MA28348A1 (fr) | 2004-02-04 | 2006-08-04 | Pipéridinylcarbonyl-pyrrolidines et leur utilisation comme agonistes de mélanocortine |
Country Status (25)
Country | Link |
---|---|
EP (1) | EP1716135B1 (fr) |
JP (1) | JP4031814B2 (fr) |
KR (1) | KR100830763B1 (fr) |
CN (1) | CN1930146A (fr) |
AP (1) | AP2006003699A0 (fr) |
AR (1) | AR048232A1 (fr) |
AT (1) | ATE511507T1 (fr) |
AU (1) | AU2005213538A1 (fr) |
BR (1) | BRPI0507435A (fr) |
CA (1) | CA2555800C (fr) |
CR (1) | CR8545A (fr) |
EA (1) | EA011159B1 (fr) |
EC (1) | ECSP066751A (fr) |
GB (1) | GB0402492D0 (fr) |
GE (1) | GEP20084361B (fr) |
IL (1) | IL177004A0 (fr) |
MA (1) | MA28348A1 (fr) |
NL (1) | NL1028193C2 (fr) |
NO (1) | NO20063944L (fr) |
PA (1) | PA8623101A1 (fr) |
PE (1) | PE20050772A1 (fr) |
TW (1) | TWI300066B (fr) |
UY (1) | UY28737A1 (fr) |
WO (1) | WO2005077935A1 (fr) |
ZA (1) | ZA200606236B (fr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009503050A (ja) * | 2005-08-04 | 2009-01-29 | ファイザー・リミテッド | ピペリジノイル−ピロリジンおよびピペリジノイル−ピペリジン化合物 |
EP1940842B1 (fr) * | 2005-09-29 | 2012-05-30 | Merck Sharp & Dohme Corp. | Dérivés acylés de spiropipéridine en tant que modulateurs du récepteur de la mélanocortine-4 |
CA2625877A1 (fr) * | 2005-10-18 | 2007-04-26 | Merck & Co., Inc. | Derives de spiropiperidine acyles utilises en tant que modulateurs vis-a-vis du recepteur de melanocortine-4 |
DK1989196T3 (da) * | 2006-02-23 | 2013-04-15 | Pfizer Ltd | Piperidinoylpyrrolidiner som melanocortin-type 4-receptoragonister |
JP5243274B2 (ja) * | 2006-02-23 | 2013-07-24 | ファイザー・リミテッド | 4型メラノコルチン受容体アゴニストのピペリジノイルピロリジン |
KR20100049644A (ko) | 2007-08-07 | 2010-05-12 | 다케다 야쿠힌 고교 가부시키가이샤 | 안드로겐 수용체 조절제로서의 피롤리딘-2-온 유도체 |
UA99555C2 (en) | 2008-11-12 | 2012-08-27 | Элджи Лайф Саенсез Лтд. | Melanocortin receptor agonists |
US8476227B2 (en) | 2010-01-22 | 2013-07-02 | Ethicon Endo-Surgery, Inc. | Methods of activating a melanocortin-4 receptor pathway in obese subjects |
US9044606B2 (en) | 2010-01-22 | 2015-06-02 | Ethicon Endo-Surgery, Inc. | Methods and devices for activating brown adipose tissue using electrical energy |
AU2015268505C1 (en) | 2014-05-29 | 2018-04-05 | Mitsubishi Tanabe Pharma Corporation | Novel pyrrolidine compound and application as melanocortin receptor agonist |
US10080884B2 (en) | 2014-12-29 | 2018-09-25 | Ethicon Llc | Methods and devices for activating brown adipose tissue using electrical energy |
US10092738B2 (en) | 2014-12-29 | 2018-10-09 | Ethicon Llc | Methods and devices for inhibiting nerves when activating brown adipose tissue |
PE20180690A1 (es) | 2015-04-27 | 2018-04-23 | Intercept Pharmaceuticals Inc | Composiciones de acido obeticolico y metodos de uso |
ES2753227T3 (es) | 2015-08-04 | 2020-04-07 | Astellas Pharma Inc | Derivado de piperazina |
CN112694436B (zh) * | 2020-12-30 | 2022-07-08 | 济南周行医药科技有限公司 | 一种槟榔碱的合成方法 |
CN114211258B (zh) * | 2021-11-04 | 2023-09-26 | 江阴市大久金属科技有限公司 | 高精密无缝钢管制备工艺 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE358481T1 (de) * | 2001-02-28 | 2007-04-15 | Merck & Co Inc | Acylierte piperidinderivate als melanocortin-4- rezeptoragonisten |
US7015235B2 (en) * | 2001-02-28 | 2006-03-21 | Merck & Co., Inc. | Acylated piperidine derivatives as melanocortin-4 receptor agonists |
-
2004
- 2004-02-04 GB GBGB0402492.3A patent/GB0402492D0/en not_active Ceased
-
2005
- 2005-01-26 AU AU2005213538A patent/AU2005213538A1/en not_active Abandoned
- 2005-01-26 KR KR1020067015811A patent/KR100830763B1/ko not_active IP Right Cessation
- 2005-01-26 BR BRPI0507435-5A patent/BRPI0507435A/pt not_active IP Right Cessation
- 2005-01-26 JP JP2006551945A patent/JP4031814B2/ja not_active Expired - Fee Related
- 2005-01-26 GE GEAP20059564A patent/GEP20084361B/en unknown
- 2005-01-26 EA EA200601279A patent/EA011159B1/ru not_active IP Right Cessation
- 2005-01-26 CN CNA2005800075736A patent/CN1930146A/zh active Pending
- 2005-01-26 AT AT05702363T patent/ATE511507T1/de not_active IP Right Cessation
- 2005-01-26 EP EP05702363A patent/EP1716135B1/fr not_active Expired - Lifetime
- 2005-01-26 WO PCT/IB2005/000208 patent/WO2005077935A1/fr active Application Filing
- 2005-01-26 AP AP2006003699A patent/AP2006003699A0/xx unknown
- 2005-01-26 CA CA2555800A patent/CA2555800C/fr not_active Expired - Fee Related
- 2005-02-02 PE PE2005000122A patent/PE20050772A1/es not_active Application Discontinuation
- 2005-02-03 TW TW094103372A patent/TWI300066B/zh active
- 2005-02-03 AR ARP050100409A patent/AR048232A1/es not_active Application Discontinuation
- 2005-02-03 UY UY28737A patent/UY28737A1/es not_active Application Discontinuation
- 2005-02-04 NL NL1028193A patent/NL1028193C2/nl not_active IP Right Cessation
- 2005-02-04 PA PA20058623101A patent/PA8623101A1/es unknown
-
2006
- 2006-07-20 IL IL177004A patent/IL177004A0/en unknown
- 2006-07-27 ZA ZA200606236A patent/ZA200606236B/xx unknown
- 2006-08-03 CR CR8545A patent/CR8545A/es not_active Application Discontinuation
- 2006-08-03 EC EC2006006751A patent/ECSP066751A/es unknown
- 2006-08-04 MA MA29242A patent/MA28348A1/fr unknown
- 2006-09-04 NO NO20063944A patent/NO20063944L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
PE20050772A1 (es) | 2005-10-31 |
ZA200606236B (en) | 2008-04-30 |
BRPI0507435A (pt) | 2007-07-03 |
TW200526625A (en) | 2005-08-16 |
KR20060127125A (ko) | 2006-12-11 |
AP2006003699A0 (en) | 2006-08-31 |
GB0402492D0 (en) | 2004-03-10 |
NO20063944L (no) | 2006-10-31 |
NL1028193C2 (nl) | 2006-04-20 |
UY28737A1 (es) | 2005-09-30 |
EA200601279A1 (ru) | 2006-12-29 |
CR8545A (es) | 2007-09-03 |
EP1716135B1 (fr) | 2011-06-01 |
CA2555800A1 (fr) | 2005-08-25 |
ECSP066751A (es) | 2006-11-16 |
CA2555800C (fr) | 2010-06-15 |
TWI300066B (en) | 2008-08-21 |
GEP20084361B (en) | 2008-04-29 |
CN1930146A (zh) | 2007-03-14 |
PA8623101A1 (es) | 2006-05-16 |
ATE511507T1 (de) | 2011-06-15 |
JP4031814B2 (ja) | 2008-01-09 |
JP2007534668A (ja) | 2007-11-29 |
AU2005213538A1 (en) | 2005-08-25 |
WO2005077935A1 (fr) | 2005-08-25 |
IL177004A0 (en) | 2006-12-10 |
NL1028193A1 (nl) | 2005-08-08 |
EA011159B1 (ru) | 2009-02-27 |
KR100830763B1 (ko) | 2008-05-19 |
EP1716135A1 (fr) | 2006-11-02 |
AR048232A1 (es) | 2006-04-12 |
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