ATE511507T1 - Piperidinylcarbonylpyrrolidine und deren verwendung als melanocortinagonisten - Google Patents

Piperidinylcarbonylpyrrolidine und deren verwendung als melanocortinagonisten

Info

Publication number: ATE511507T1
Authority: AT; Austria
Prior art keywords: piperidinylcarbonylpyrrolidine; melanocortinagonists
Prior art date: 2004-02-04

Application number

AT05702363T

Other languages

English (en)

Inventor

Andrew A Calbrese

David S Fradet

David Hepworth

Mark Lansdell

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-02-04

Filing date

2005-01-26

Publication date

2011-06-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34864830&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE511507(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-06-03 Priority claimed from GB0412417A external-priority patent/GB0412417D0/en

2004-11-19 Priority claimed from GB0425530A external-priority patent/GB0425530D0/en

2005-01-26 Application filed by Pfizer filed Critical Pfizer

2011-06-15 Application granted granted Critical

2011-06-15 Publication of ATE511507T1 publication Critical patent/ATE511507T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Diabetes (AREA)
Obesity (AREA)
Hematology (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Psychiatry (AREA)
Immunology (AREA)
Gynecology & Obstetrics (AREA)
Pain & Pain Management (AREA)
Dermatology (AREA)
Rheumatology (AREA)
Gastroenterology & Hepatology (AREA)
Physical Education & Sports Medicine (AREA)
Hospice & Palliative Care (AREA)
Addiction (AREA)
Cardiology (AREA)
Pregnancy & Childbirth (AREA)
Child & Adolescent Psychology (AREA)
Anesthesiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Heart & Thoracic Surgery (AREA)
Emergency Medicine (AREA)

AT05702363T 2004-02-04 2005-01-26 Piperidinylcarbonylpyrrolidine und deren verwendung als melanocortinagonisten ATE511507T1 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GBGB0402492.3A GB0402492D0 (en)	2004-02-04	2004-02-04	Pharmaceutically active compounds
GB0412417A GB0412417D0 (en)	2004-06-03	2004-06-03	Pharmaceutically active compounds
GB0425530A GB0425530D0 (en)	2004-11-19	2004-11-19	Pharmaceutically active compounds
PCT/IB2005/000208 WO2005077935A1 (en)	2004-02-04	2005-01-26	Piperidinylcarbonyl-pyrrolidines and their use as melanocortin agonists

Publications (1)

Publication Number	Publication Date
ATE511507T1 true ATE511507T1 (de)	2011-06-15

Family

ID=34864830

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT05702363T ATE511507T1 (de)	2004-02-04	2005-01-26	Piperidinylcarbonylpyrrolidine und deren verwendung als melanocortinagonisten

Country Status (25)

Country	Link
EP (1)	EP1716135B1 (de)
JP (1)	JP4031814B2 (de)
KR (1)	KR100830763B1 (de)
CN (1)	CN1930146A (de)
AP (1)	AP2006003699A0 (de)
AR (1)	AR048232A1 (de)
AT (1)	ATE511507T1 (de)
AU (1)	AU2005213538A1 (de)
BR (1)	BRPI0507435A (de)
CA (1)	CA2555800C (de)
CR (1)	CR8545A (de)
EA (1)	EA011159B1 (de)
EC (1)	ECSP066751A (de)
GB (1)	GB0402492D0 (de)
GE (1)	GEP20084361B (de)
IL (1)	IL177004A0 (de)
MA (1)	MA28348A1 (de)
NL (1)	NL1028193C2 (de)
NO (1)	NO20063944L (de)
PA (1)	PA8623101A1 (de)
PE (1)	PE20050772A1 (de)
TW (1)	TWI300066B (de)
UY (1)	UY28737A1 (de)
WO (1)	WO2005077935A1 (de)
ZA (1)	ZA200606236B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2009503050A (ja) *	2005-08-04	2009-01-29	ファイザー・リミテッド	ピペリジノイル−ピロリジンおよびピペリジノイル−ピペリジン化合物
EP1940842B1 (de) *	2005-09-29	2012-05-30	Merck Sharp & Dohme Corp.	Acylierte spiropiperidinderivate als modulatoren des melanocortin-4-rezeptors
CA2625877A1 (en) *	2005-10-18	2007-04-26	Merck & Co., Inc.	Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
DK1989196T3 (da) *	2006-02-23	2013-04-15	Pfizer Ltd	Piperidinoylpyrrolidiner som melanocortin-type 4-receptoragonister
JP5243274B2 (ja) *	2006-02-23	2013-07-24	ファイザー・リミテッド	４型メラノコルチン受容体アゴニストのピペリジノイルピロリジン
KR20100049644A (ko)	2007-08-07	2010-05-12	다케다 야쿠힌 고교 가부시키가이샤	안드로겐 수용체 조절제로서의 피롤리딘-2-온 유도체
UA99555C2 (en)	2008-11-12	2012-08-27	Элджи Лайф Саенсез Лтд.	Melanocortin receptor agonists
US8476227B2 (en)	2010-01-22	2013-07-02	Ethicon Endo-Surgery, Inc.	Methods of activating a melanocortin-4 receptor pathway in obese subjects
US9044606B2 (en)	2010-01-22	2015-06-02	Ethicon Endo-Surgery, Inc.	Methods and devices for activating brown adipose tissue using electrical energy
AU2015268505C1 (en)	2014-05-29	2018-04-05	Mitsubishi Tanabe Pharma Corporation	Novel pyrrolidine compound and application as melanocortin receptor agonist
US10080884B2 (en)	2014-12-29	2018-09-25	Ethicon Llc	Methods and devices for activating brown adipose tissue using electrical energy
US10092738B2 (en)	2014-12-29	2018-10-09	Ethicon Llc	Methods and devices for inhibiting nerves when activating brown adipose tissue
PE20180690A1 (es)	2015-04-27	2018-04-23	Intercept Pharmaceuticals Inc	Composiciones de acido obeticolico y metodos de uso
ES2753227T3 (es)	2015-08-04	2020-04-07	Astellas Pharma Inc	Derivado de piperazina
CN112694436B (zh) *	2020-12-30	2022-07-08	济南周行医药科技有限公司	一种槟榔碱的合成方法
CN114211258B (zh) *	2021-11-04	2023-09-26	江阴市大久金属科技有限公司	高精密无缝钢管制备工艺

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE358481T1 (de) *	2001-02-28	2007-04-15	Merck & Co Inc	Acylierte piperidinderivate als melanocortin-4- rezeptoragonisten
US7015235B2 (en) *	2001-02-28	2006-03-21	Merck & Co., Inc.	Acylated piperidine derivatives as melanocortin-4 receptor agonists

2004
- 2004-02-04 GB GBGB0402492.3A patent/GB0402492D0/en not_active Ceased
2005
- 2005-01-26 AU AU2005213538A patent/AU2005213538A1/en not_active Abandoned
- 2005-01-26 KR KR1020067015811A patent/KR100830763B1/ko not_active IP Right Cessation
- 2005-01-26 BR BRPI0507435-5A patent/BRPI0507435A/pt not_active IP Right Cessation
- 2005-01-26 JP JP2006551945A patent/JP4031814B2/ja not_active Expired - Fee Related
- 2005-01-26 GE GEAP20059564A patent/GEP20084361B/en unknown
- 2005-01-26 EA EA200601279A patent/EA011159B1/ru not_active IP Right Cessation
- 2005-01-26 CN CNA2005800075736A patent/CN1930146A/zh active Pending
- 2005-01-26 AT AT05702363T patent/ATE511507T1/de not_active IP Right Cessation
- 2005-01-26 EP EP05702363A patent/EP1716135B1/de not_active Expired - Lifetime
- 2005-01-26 WO PCT/IB2005/000208 patent/WO2005077935A1/en active Application Filing
- 2005-01-26 AP AP2006003699A patent/AP2006003699A0/xx unknown
- 2005-01-26 CA CA2555800A patent/CA2555800C/en not_active Expired - Fee Related
- 2005-02-02 PE PE2005000122A patent/PE20050772A1/es not_active Application Discontinuation
- 2005-02-03 TW TW094103372A patent/TWI300066B/zh active
- 2005-02-03 AR ARP050100409A patent/AR048232A1/es not_active Application Discontinuation
- 2005-02-03 UY UY28737A patent/UY28737A1/es not_active Application Discontinuation
- 2005-02-04 NL NL1028193A patent/NL1028193C2/nl not_active IP Right Cessation
- 2005-02-04 PA PA20058623101A patent/PA8623101A1/es unknown
2006
- 2006-07-20 IL IL177004A patent/IL177004A0/en unknown
- 2006-07-27 ZA ZA200606236A patent/ZA200606236B/xx unknown
- 2006-08-03 CR CR8545A patent/CR8545A/es not_active Application Discontinuation
- 2006-08-03 EC EC2006006751A patent/ECSP066751A/es unknown
- 2006-08-04 MA MA29242A patent/MA28348A1/fr unknown
- 2006-09-04 NO NO20063944A patent/NO20063944L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
MA28348A1 (fr)	2006-12-01
PE20050772A1 (es)	2005-10-31
ZA200606236B (en)	2008-04-30
BRPI0507435A (pt)	2007-07-03
TW200526625A (en)	2005-08-16
KR20060127125A (ko)	2006-12-11
AP2006003699A0 (en)	2006-08-31
GB0402492D0 (en)	2004-03-10
NO20063944L (no)	2006-10-31
NL1028193C2 (nl)	2006-04-20
UY28737A1 (es)	2005-09-30
EA200601279A1 (ru)	2006-12-29
CR8545A (es)	2007-09-03
EP1716135B1 (de)	2011-06-01
CA2555800A1 (en)	2005-08-25
ECSP066751A (es)	2006-11-16
CA2555800C (en)	2010-06-15
TWI300066B (en)	2008-08-21
GEP20084361B (en)	2008-04-29
CN1930146A (zh)	2007-03-14
PA8623101A1 (es)	2006-05-16
JP4031814B2 (ja)	2008-01-09
JP2007534668A (ja)	2007-11-29
AU2005213538A1 (en)	2005-08-25
WO2005077935A1 (en)	2005-08-25
IL177004A0 (en)	2006-12-10
NL1028193A1 (nl)	2005-08-08
EA011159B1 (ru)	2009-02-27
KR100830763B1 (ko)	2008-05-19
EP1716135A1 (de)	2006-11-02
AR048232A1 (es)	2006-04-12

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ATE511507T1 (de)	2011-06-15	Piperidinylcarbonylpyrrolidine und deren verwendung als melanocortinagonisten
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Legal Events

Date	Code	Title	Description
2011-12-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties