LV10270A - 2-[(2-Piridinil)metilsulfinil-(vai sulfonil)]-1H-benzimidazol-1-ila atvasinajumi to iegusanas panemiens farmaceitiska kompozicija uz to bazes pielietojums - Google Patents

2-[(2-Piridinil)metilsulfinil-(vai sulfonil)]-1H-benzimidazol-1-ila atvasinajumi to iegusanas panemiens farmaceitiska kompozicija uz to bazes pielietojums

Info

Publication number: LV10270A
Authority: LV; Latvia
Prior art keywords: methylsulfinyl; benzimidazol; pyridinyl; sulfonyl; base
Prior art date: 1985-10-29

Application number

LV930856A

Other languages

English (en)

Other versions

LV10270B (en

Inventor

Tomas Boerje Alminger

Per Lennart Lindberg

Gunnel Elisabeth Sunden

Haekan Sigurd Larsson

Original Assignee

Haessle Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-10-29

Filing date

1993-06-30

Publication date

1994-10-20

1993-06-30 Application filed by Haessle Ab filed Critical Haessle Ab

1994-10-20 Publication of LV10270A publication Critical patent/LV10270A/lv

1995-04-20 Publication of LV10270B publication Critical patent/LV10270B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Indole Compounds (AREA)

LVP-93-856A 1985-10-29 1993-06-30 Novel pharmacological compounds LV10270B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE8505112A SE8505112D0 (sv)	1985-10-29	1985-10-29	Novel pharmacological compounds
PCT/SE1986/000493 WO1987002668A1 (en)	1985-10-29	1986-10-28	Novel pharmacological compounds

Publications (2)

Publication Number	Publication Date
LV10270A true LV10270A (lv)	1994-10-20
LV10270B LV10270B (en)	1995-04-20

Family

ID=20361960

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LVP-93-856A LV10270B (en)	1985-10-29	1993-06-30	Novel pharmacological compounds

Country Status (31)

Country	Link
US (1)	US5021433A (lv)
EP (2)	EP0221041A3 (lv)
JP (2)	JPH0780874B2 (lv)
KR (1)	KR950009858B1 (lv)
CN (1)	CN1022487C (lv)
AT (1)	ATE79619T1 (lv)
AU (1)	AU598491B2 (lv)
CS (1)	CS272767B2 (lv)
DD (1)	DD252375A5 (lv)
DE (1)	DE3686483T2 (lv)
DK (1)	DK320587D0 (lv)
EG (1)	EG17753A (lv)
ES (1)	ES2051696T3 (lv)
FI (1)	FI91151C (lv)
GR (1)	GR3006177T3 (lv)
HU (1)	HU198474B (lv)
IE (1)	IE59167B1 (lv)
IL (1)	IL80437A0 (lv)
IS (1)	IS1564B (lv)
JO (1)	JO1502B1 (lv)
LT (1)	LTIP1681A (lv)
LV (1)	LV10270B (lv)
MY (1)	MY101791A (lv)
NO (1)	NO171365C (lv)
NZ (1)	NZ218028A (lv)
PH (1)	PH25319A (lv)
PL (1)	PL150240B1 (lv)
PT (1)	PT83647B (lv)
SE (1)	SE8505112D0 (lv)
WO (1)	WO1987002668A1 (lv)
ZA (1)	ZA867716B (lv)

Families Citing this family (39)

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NZ222495A (en) *	1986-11-21	1991-04-26	Haessle Ab	Benzimidazole derivatives and pharmaceutical compositions
US5175286A (en) *	1988-09-20	1992-12-29	Hisamitsu Pharmaceutical Co., Inc.	Dibenz[b,e]oxepin derivatives
EG19302A (en) *	1988-12-22	1994-11-30	Haessle Ab	Compound with gastric acid inhibitory effect and process for its preparation
SE8804629D0 (sv) *	1988-12-22	1988-12-22	Ab Haessle	New therapeutically active compounds
US4965269A (en) *	1989-12-20	1990-10-23	Ab Hassle	Therapeutically active chloro substituted benzimidazoles
US5274099A (en) *	1989-12-20	1993-12-28	Aktiebolaget Hassle	Therapeutically active fluoro substituted benzimidazoles
US5049674A (en) *	1989-12-20	1991-09-17	Aktiebolaget Hassle	Therapeutically active fluoro substituted benzimidazoles
CA2083606C (en) *	1990-06-20	2001-08-21	Arne Elof Brandstrom	Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use
SE9002206D0 (sv)	1990-06-20	1990-06-20	Haessle Ab	New compounds
ES2048109B1 (es) *	1992-07-20	1994-12-16	Espanola Prod Quimicos	Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol.
WO1995032957A1 (en) *	1994-05-27	1995-12-07	Astra Aktiebolag	Novel ethoxycarbonyloxymethyl derivatives of substituted benzimidazoles
US6093734A (en) *	1998-08-10	2000-07-25	Partnership Of Michael E. Garst, George Sachs, And Jai Moo Shin	Prodrugs of proton pump inhibitors
NZ510180A (en) *	1998-08-10	2002-11-26	Univ California	Prodrugs of the pyridyl-methylsulphonyl-benzimidazole type proton pump inhibitors
US6852739B1 (en)	1999-02-26	2005-02-08	Nitromed Inc.	Methods using proton pump inhibitors and nitric oxide donors
US6369087B1 (en) *	1999-08-26	2002-04-09	Robert R. Whittle	Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
EP1334971A4 (en) *	2000-10-12	2004-05-12	Takeda Chemical Industries Ltd	BENZIMIDAZOLE COMPOUNDS, METHOD FOR THE PRODUCTION AND USE THEREOF
WO2003027098A1 (fr) *	2001-09-25	2003-04-03	Takeda Chemical Industries, Ltd.	Compose de benzymidazole, procede de production et d'utilisation de celui-ci
US7410981B2 (en) *	2002-06-14	2008-08-12	Takeda Pharmaceutical Company Limited	Prodrugs of imidazole derivatives, for use as proton pump inhibitors in the treatment of e.g. peptic ulcers
MXPA05000657A (es) *	2002-07-19	2005-08-19	Winston Pharmaceuticals Llc	Profarmacos de los inhibidores de bomba de protones.
JP4634144B2 (ja)	2002-08-01	2011-02-16	ニコックスエスエー	ニトロソ化プロトンポンプ阻害剤、組成物および使用方法
MY148805A (en)	2002-10-16	2013-05-31	Takeda Pharmaceutical	Controlled release preparation
EP2112920B1 (en) *	2003-06-26	2018-07-25	Intellipharmaceutics Corp.	Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
US20060241037A1 (en) *	2003-10-03	2006-10-26	Allergan Inc.	Compositions comprising trefoil factor family peptides and/or mucoadhesives and proton pump ihhibitor prodrugs
US20050075371A1 (en) *	2003-10-03	2005-04-07	Allergan, Inc.	Methods and compositions for the oral administration of prodrugs of proton pump inhibitors
BRPI0507784A (pt) *	2004-02-18	2007-07-17	Allergan Inc	métodos e composições para a administração de pró-fármacos de inibidores da bomba de prótons
US20070161679A1 (en) *	2004-02-18	2007-07-12	Allergan, Inc.	Method and compositions for the intravenous administration of compounds related to proton pump inhibitors
MXPA06011820A (es) *	2004-04-16	2006-12-15	Santarus Inc	Combinacion de inhibidor de bomba de proton, agente regulador del ph y agente procinetico.
ATE437869T1 (de)	2004-04-28	2009-08-15	Hetero Drugs Ltd	Verfahren zur herstellung von pyridinylmethyl-1h- benzimidazolverbindungen in enantiomerenangereicherter form oder als einzelne enantiomere
PT1748998E (pt)	2004-05-28	2010-03-24	Hetero Drugs Ltd	Novo processo de síntese estereoselectiva de sulfóxidos de benzimidazol
US8394409B2 (en) *	2004-07-01	2013-03-12	Intellipharmaceutics Corp.	Controlled extended drug release technology
US10624858B2 (en)	2004-08-23	2020-04-21	Intellipharmaceutics Corp	Controlled release composition using transition coating, and method of preparing same
US10064828B1 (en)	2005-12-23	2018-09-04	Intellipharmaceutics Corp.	Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
EP2007360B1 (en) *	2006-04-03	2014-11-26	Isa Odidi	Controlled release delivery device comprising an organosol coat
US10960077B2 (en)	2006-05-12	2021-03-30	Intellipharmaceutics Corp.	Abuse and alcohol resistant drug composition
US20100317689A1 (en) *	2006-09-19	2010-12-16	Garst Michael E	Prodrugs of proton pump inhibitors including the 1h-imidazo[4,5-b] pyridine moiety
CA2667682A1 (en)	2006-10-27	2008-05-15	The Curators Of The University Of Missouri	Compositions comprising acid labile proton pump inhibiting agents, at least one other pharmaceutically active agent and methods of using same
US20080194307A1 (en) *	2007-02-13	2008-08-14	Jeff Sanger	Sports-based game of chance
WO2009105568A1 (en)	2008-02-20	2009-08-27	The Curators Of The University Of Missouri	Composition comprising a combination of omeprazole and lansoprazole, and a buffering agent, and methods of using same
EP2521545B1 (en) *	2010-01-07	2019-11-27	Alkermes Pharma Ireland Limited	Prodrugs of heteroaromatic compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4045564A (en) *	1974-02-18	1977-08-30	Ab Hassle	Benzimidazole derivatives useful as gastric acid secretion inhibitors
SE418966B (sv) *	1974-02-18	1981-07-06	Haessle Ab	Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) *	1974-05-16	1981-01-26	Haessle Ab	Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (lv) *	1977-09-19	1981-07-25	Hoffmann La Roche
SE7804231L (sv) *	1978-04-14	1979-10-15	Haessle Ab	Magsyrasekretionsmedel
US4359465A (en) *	1980-07-28	1982-11-16	The Upjohn Company	Methods for treating gastrointestinal inflammation
CH644116A5 (de) *	1980-08-21	1984-07-13	Hoffmann La Roche	Imidazolderivate.
SE8300736D0 (sv) *	1983-02-11	1983-02-11	Haessle Ab	Novel pharmacologically active compounds
IL75400A (en) *	1984-06-16	1988-10-31	Byk Gulden Lomberg Chem Fab	Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
ZA856671B (en) *	1984-09-24	1986-04-30	Upjohn Co	N-substituted derivatives of 2-(pyridylaklenesulfinyl)benzimidazoles as gastric antisecretory agents
AU568441B2 (en) *	1984-09-24	1987-12-24	Upjohn Company, The	2-(pyridylalkenesulfinyl) benzimidazole derivatives

1985
- 1985-10-29 SE SE8505112A patent/SE8505112D0/xx unknown
1986
- 1986-10-09 ZA ZA867716A patent/ZA867716B/xx unknown
- 1986-10-22 NZ NZ218028A patent/NZ218028A/xx unknown
- 1986-10-22 EG EG661/86A patent/EG17753A/xx active
- 1986-10-23 IE IE280586A patent/IE59167B1/en not_active IP Right Cessation
- 1986-10-24 PH PH34408A patent/PH25319A/en unknown
- 1986-10-27 DD DD86295633A patent/DD252375A5/de not_active IP Right Cessation
- 1986-10-27 JO JO19861502A patent/JO1502B1/en active
- 1986-10-27 MY MYPI86000038A patent/MY101791A/en unknown
- 1986-10-28 ES ES86906498T patent/ES2051696T3/es not_active Expired - Lifetime
- 1986-10-28 HU HU865443A patent/HU198474B/hu not_active IP Right Cessation
- 1986-10-28 WO PCT/SE1986/000493 patent/WO1987002668A1/en active IP Right Grant
- 1986-10-28 KR KR1019870700555A patent/KR950009858B1/ko active IP Right Grant
- 1986-10-28 IL IL80437A patent/IL80437A0/xx not_active IP Right Cessation
- 1986-10-28 AU AU65429/86A patent/AU598491B2/en not_active Ceased
- 1986-10-28 EP EP86850378A patent/EP0221041A3/en active Pending
- 1986-10-28 IS IS3156A patent/IS1564B/is unknown
- 1986-10-28 JP JP61505700A patent/JPH0780874B2/ja not_active Expired - Lifetime
- 1986-10-28 AT AT86906498T patent/ATE79619T1/de not_active IP Right Cessation
- 1986-10-28 DE DE8686906498T patent/DE3686483T2/de not_active Expired - Fee Related
- 1986-10-28 EP EP86906498A patent/EP0233284B1/en not_active Expired - Lifetime
- 1986-10-29 PL PL1986262105A patent/PL150240B1/pl unknown
- 1986-10-29 PT PT83647A patent/PT83647B/pt not_active IP Right Cessation
- 1986-10-29 CN CN86107595A patent/CN1022487C/zh not_active Expired - Lifetime
- 1986-10-29 CS CS782686A patent/CS272767B2/cs unknown
1987
- 1987-06-24 DK DK320587A patent/DK320587D0/da not_active Application Discontinuation
- 1987-06-26 NO NO872686A patent/NO171365C/no unknown
- 1987-06-29 FI FI872864A patent/FI91151C/sv not_active IP Right Cessation
1988
- 1988-05-12 US US07/195,343 patent/US5021433A/en not_active Expired - Fee Related
1992
- 1992-11-05 GR GR920402498T patent/GR3006177T3/el unknown
1993
- 1993-06-30 LV LVP-93-856A patent/LV10270B/xx unknown
- 1993-12-28 LT LTIP1681A patent/LTIP1681A/xx not_active Application Discontinuation
1994
- 1994-12-21 JP JP6318132A patent/JPH0826014B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DD252375A5 (de)	1987-12-16
LTIP1681A (en)	1995-09-25
CN1022487C (zh)	1993-10-20
FI872864A0 (fi)	1987-06-29
CS782686A2 (en)	1990-05-14
NZ218028A (en)	1990-02-26
KR870700620A (ko)	1987-12-30
MY101791A (en)	1992-01-31
IE862805L (en)	1987-04-29
GR3006177T3 (lv)	1993-06-21
EP0233284A1 (en)	1987-08-26
FI91151C (sv)	1994-05-25
JPS63501151A (ja)	1988-04-28
AU598491B2 (en)	1990-06-28
ATE79619T1 (de)	1992-09-15
KR950009858B1 (ko)	1995-08-29
JPH0826014B2 (ja)	1996-03-13
JO1502B1 (en)	1989-01-25
EP0233284B1 (en)	1992-08-19
NO872686L (no)	1987-06-26
IS3156A7 (is)	1987-04-30
ZA867716B (en)	1987-05-27
PT83647A (en)	1986-11-01
HU198474B (en)	1989-10-30
IS1564B (is)	1994-12-13
DE3686483T2 (de)	1993-02-04
CS272767B2 (en)	1991-02-12
PL262105A1 (en)	1988-08-18
PT83647B (pt)	1989-05-31
NO872686D0 (no)	1987-06-26
IL80437A0 (en)	1987-01-30
DE3686483D1 (de)	1992-09-24
AU6542986A (en)	1987-05-19
PH25319A (lv)	1991-04-30
EP0221041A3 (en)	1987-10-28
PL150240B1 (en)	1990-05-31
SE8505112D0 (sv)	1985-10-29
US5021433A (en)	1991-06-04
EG17753A (en)	1991-12-30
JPH0780874B2 (ja)	1995-08-30
DK320587A (da)	1987-06-24
FI872864A (fi)	1987-06-29
DK320587D0 (da)	1987-06-24
HUT43843A (en)	1987-12-28
EP0221041A2 (en)	1987-05-06
LV10270B (en)	1995-04-20
JPH07188216A (ja)	1995-07-25
CN86107595A (zh)	1987-07-08
NO171365B (no)	1992-11-23
WO1987002668A1 (en)	1987-05-07
ES2051696T3 (es)	1994-07-01
IE59167B1 (en)	1994-01-12
NO171365C (no)	1993-03-03
FI91151B (fi)	1994-02-15

Publication	Publication Date	Title
LV10270A (lv)	1994-10-20	2-[(2-Piridinil)metilsulfinil-(vai sulfonil)]-1H-benzimidazol-1-ila atvasinajumi to iegusanas panemiens farmaceitiska kompozicija uz to bazes pielietojums
SE8700499L (sv)	1987-02-10	Nya farmakologiskt aktiva foreningar
SE8804629D0 (sv)	1988-12-22	New therapeutically active compounds
KR890700125A (ko)	1989-03-02	신규 벤즈이미다졸 유도체, 그 제조방법 및 이 화합물을 함유하는 제약 조성물
SE8404065D0 (sv)	1984-08-10	Novel biologically active compounds
IT1224405B (it)	1990-10-04	Composti attivi sul sistema cardiovascolare
SE8600658D0 (sv)	1986-02-14	Novel composition of matter
DK122191A (da)	1991-06-24	Benzimidazolderivat og fysiologisk acceptable salte heraf samt fremgangsmaade til fremstilling af samme
ATE123497T1 (de)	1995-06-15	Substituierte pyridin-verbindungen, ihre herstellung und sie enthaltende pharmazeutische zusammensetzungen.
IT1224404B (it)	1990-10-04	Composti attivi sul sistema cardiovascolare
JO1519B1 (en)	1989-01-25	New compounds (new benzimidazole derivatives are effective as ulcers)