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KR960016906A - 약독화 수두 생바이러스 백신 및 그의 제조방법 - Google Patents

약독화 수두 생바이러스 백신 및 그의 제조방법 Download PDF

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Publication number
KR960016906A
KR960016906A KR1019940030949A KR19940030949A KR960016906A KR 960016906 A KR960016906 A KR 960016906A KR 1019940030949 A KR1019940030949 A KR 1019940030949A KR 19940030949 A KR19940030949 A KR 19940030949A KR 960016906 A KR960016906 A KR 960016906A
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KR
South Korea
Prior art keywords
virus
attenuated
chickenpox
mav
virus vaccine
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Application number
KR1019940030949A
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English (en)
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KR0135614B1 (ko
Inventor
박송용
황규계
전복환
우규진
문홍모
Original Assignee
허영섭
재단법인 목암생명공학연구소
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 허영섭, 재단법인 목암생명공학연구소 filed Critical 허영섭
Priority to KR1019940030949A priority Critical patent/KR0135614B1/ko
Publication of KR960016906A publication Critical patent/KR960016906A/ko
Application granted granted Critical
Publication of KR0135614B1 publication Critical patent/KR0135614B1/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A61K39/25—Varicella-zoster virus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

본 발명은 사람 태아의 폐조직으로부터 초대배향하여 확립한 세포주(LuMA)를 이용하여, 수두 환자의 수포로부터 분리하여 여러 세포주에 계대배양함으로써 약독화한 수두 바이러스(MAV/06)주를 증식시킨 다음, 초음파처리를 통하여 수두 바이러스를 세포로부터 유리시킨 후 동결건조하여 제조한 면역원성이 우수한 약독화 수두 생바이러스 백신에 관한 것이다.

Description

약독화 수두 생바이러스 백신 및 그의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (3)

  1. 수두 바이러스(MAV/06)주 (KFCC-1084)를 유효성분으로 하고, 약학적으로 허용되는 담체를 함유하는 약독화 수두 생바이러스 백신.
  2. 제1항에 있어서, 수두 바이러스(MAV/06)주는 1000 플라크 생성단위(PFU) 이상을 함유하는 것을 특징으로 하는 약독화 수두 생바이러스 백신.
  3. 수두 바이러스(MAV/06)주 (KFCC-1084)를 사람 정상 이배체 세포주 LuMA세포(KCTC 0035BP)에 배양하는 공정을 포함하는 제1항 기재의 약독화 수두 생바이러스 백신의 제조방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019940030949A 1994-11-23 1994-11-23 약독화 수두 생바이러스 백신 및 그의 제조방법 KR0135614B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019940030949A KR0135614B1 (ko) 1994-11-23 1994-11-23 약독화 수두 생바이러스 백신 및 그의 제조방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019940030949A KR0135614B1 (ko) 1994-11-23 1994-11-23 약독화 수두 생바이러스 백신 및 그의 제조방법

Publications (2)

Publication Number Publication Date
KR960016906A true KR960016906A (ko) 1996-06-17
KR0135614B1 KR0135614B1 (ko) 1998-04-23

Family

ID=19398782

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940030949A KR0135614B1 (ko) 1994-11-23 1994-11-23 약독화 수두 생바이러스 백신 및 그의 제조방법

Country Status (1)

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KR (1) KR0135614B1 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100434024B1 (ko) * 1996-01-24 2004-07-21 주식회사 엘지생명과학 수두바이러스의대량생산방법
MX2013009723A (es) * 2011-02-24 2013-09-16 Mogam Biotech Res Inst Cepas del virus de varicela-zoster novedosas, y vacunas del virus del herpes zoster y varicela usando los mismos.

Also Published As

Publication number Publication date
KR0135614B1 (ko) 1998-04-23

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