KR950700903A - 5-ht1 작용물질로서의 아실아미노인돌 유도체(acylaminoindole derivatives as 5-ht1 agonists) - Google Patents

5-ht1 작용물질로서의 아실아미노인돌 유도체(acylaminoindole derivatives as 5-ht1 agonists)

Info

Publication number: KR950700903A
Authority: KR; South Korea
Prior art keywords: aryl; alkyl; alkylaryl; hydrogen; pct
Prior art date: 1992-04-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

KR1019940703551A

Other languages

English (en)

Other versions

KR0179074B1 (ko

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-04-10

Filing date

1994-10-07

Publication date

1995-02-20

1993-03-04 Application filed filed Critical

1995-02-20 Publication of KR950700903A publication Critical patent/KR950700903A/ko

1999-03-20 Application granted granted Critical

1999-03-20 Publication of KR0179074B1 publication Critical patent/KR0179074B1/ko

2013-03-04 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Diabetes (AREA)
Anesthesiology (AREA)
Child & Adolescent Psychology (AREA)
Cardiology (AREA)
Hematology (AREA)
Obesity (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Materials For Photolithography (AREA)
Soft Magnetic Materials (AREA)
Supply Devices, Intensifiers, Converters, And Telemotors (AREA)
Pyrrole Compounds (AREA)

KR1019940703551A 1992-04-10 1993-03-04 5-ht1 작용물질로서의 아실아미노인돌 유도체 Expired - Fee Related KR0179074B1 (ko)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US86638292A	1992-04-10	1992-04-10
US7/866382		1992-04-10
PCT/US1993/001807 WO1993021180A1 (en)	1992-04-10	1993-03-04	Acylaminoindole derivatives as 5-ht1 agonists

Publications (2)

Publication Number	Publication Date
KR950700903A true KR950700903A (ko)	1995-02-20
KR0179074B1 KR0179074B1 (ko)	1999-03-20

Family

ID=25347493

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
KR1019940703551A Expired - Fee Related KR0179074B1 (ko)	1992-04-10	1993-03-04	5-ht1 작용물질로서의 아실아미노인돌 유도체

Country Status (31)

Country	Link
US (1)	US5498626A (ko)
EP (1)	EP0635015B1 (ko)
JP (1)	JP2544704B2 (ko)
KR (1)	KR0179074B1 (ko)
CN (1)	CN1038506C (ko)
AT (1)	ATE148465T1 (ko)
AU (1)	AU670270B2 (ko)
BR (1)	BR9306221A (ko)
CA (1)	CA2132706C (ko)
CZ (1)	CZ282653B6 (ko)
DE (1)	DE69307875T2 (ko)
DK (1)	DK0635015T3 (ko)
EG (1)	EG20466A (ko)
ES (1)	ES2097496T3 (ko)
FI (2)	FI111256B (ko)
GR (1)	GR3022767T3 (ko)
HR (1)	HRP930753B1 (ko)
HU (1)	HUT64060A (ko)
IL (1)	IL105309A0 (ko)
MX (1)	MX9301996A (ko)
MY (1)	MY115278A (ko)
NO (1)	NO309860B1 (ko)
NZ (1)	NZ251047A (ko)
PL (1)	PL172232B1 (ko)
RU (1)	RU2110516C1 (ko)
SK (1)	SK278182B6 (ko)
TW (1)	TW394769B (ko)
UA (1)	UA34452C2 (ko)
WO (1)	WO1993021180A1 (ko)
YU (1)	YU48916B (ko)
ZA (1)	ZA932536B (ko)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5559129A (en) *	1990-10-15	1996-09-24	Pfizer Inc	Indole derivatives
US5607951A (en) *	1990-10-15	1997-03-04	Pfizer Inc	Indole derivatives
US5545644A (en) *	1990-10-15	1996-08-13	Pfizer Inc.	Indole derivatives
US5559246A (en) *	1990-10-15	1996-09-24	Pfizer Inc.	Indole derivatives
US5578612A (en) *	1990-10-15	1996-11-26	Pfizer Inc.	Indole derivatives
EP0635017A1 (en)	1992-04-07	1995-01-25	Pfizer Inc.	Indole derivatives as 5-ht1 agonists
US6380233B1 (en)	1992-04-07	2002-04-30	Pfizer Inc	Indole derivatives as 5-HT1 agonists
ES2070772B1 (es) *	1993-08-09	1996-02-16	Pfizer	Derivados de acilaminoindol
AU686654B2 (en) *	1993-08-31	1998-02-12	Pfizer Inc.	5-arylindole derivatives
GB9402011D0 (en) *	1994-02-02	1994-03-30	Merck Sharp & Dohme	Therapeutic agents
GB9402016D0 (en) *	1994-02-02	1994-03-30	Merck Sharp & Dohme	Therapeutic agents
US5965582A (en) *	1994-08-03	1999-10-12	Asta Medica Aktiengesellschaft	N-benzylindole and benzopyrazole derivatives with anti-asthmatic, anti-allergic, anti-inflammatory and immunemodulating effect
GB9417310D0 (en) *	1994-08-27	1994-10-19	Pfizer Ltd	Therapeutic agents
GB9420503D0 (en) *	1994-10-11	1994-11-23	Pfizer Ltd	Therapeutic agents
GB9420529D0 (en)	1994-10-12	1994-11-30	Pfizer Ltd	Indoles
AU3170099A (en) *	1998-04-16	1999-11-08	Yamanouchi Pharmaceutical Co., Ltd.	Remedies for obesity
US5994352A (en) *	1998-11-13	1999-11-30	Pfizer Inc.	5-arylindole derivatives
CA2514024A1 (en) *	2003-01-22	2004-08-05	Gtx Inc.	Treating androgen deficiency in female (adif)-associated conditions with sarms
MX2010006162A (es) *	2007-12-07	2010-06-25	Pfizer	Sal tosilato de una trans-n-isobutil-3-fluoro-3-[3-fluoro-4-(pirro lidin-1-il-metil)fenil]ciclobutanocarboxamida.
JP6440625B2 (ja)	2012-11-14	2018-12-19	ザ・ジョンズ・ホプキンス・ユニバーシティー	精神分裂病を処置するための方法および組成物
CN103408535B (zh) *	2013-08-13	2016-03-02	张家港威胜生物医药有限公司	一种依来曲普坦中间体-5-溴-3-(n-甲基吡咯啉-2-基甲基)-1h-吲哚合成工艺

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA795239B (en) *	1978-10-12	1980-11-26	Glaxo Group Ltd	Heterocyclic compounds
ZA815541B (en) *	1980-08-12	1983-03-30	Glaxo Group Ltd	Heterocyclic compounds
NZ197998A (en) *	1980-08-12	1985-08-16	Glaxo Group Ltd	5-amino(methyl)-1h-indol-3-ylalkaneamines
GB8600397D0 (en) *	1986-01-08	1986-02-12	Glaxo Group Ltd	Chemical compounds
GB8719167D0 (en) *	1987-08-13	1987-09-23	Glaxo Group Ltd	Chemical compounds
GB8724912D0 (en) *	1987-10-23	1987-11-25	Wellcome Found	Indole derivatives
GB8819024D0 (en) *	1988-08-10	1988-09-14	Glaxo Group Ltd	Chemical compounds
IL96891A0 (en) *	1990-01-17	1992-03-29	Merck Sharp & Dohme	Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them
CA2042295A1 (fr) *	1990-05-15	1991-11-16	Jacques Chauveau	Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant
HU219974B (hu) *	1990-06-07	2001-10-28	Astrazeneca Ab,	Heterociklusos csoporttal helyettesített indolszármazék, előállítása és a vegyületet hatóanyagként tartalmazó gyógyszerkészítmények
BR9106978A (pt) *	1990-10-15	1993-09-28	Pfizer	Derivados de indol
US5208248A (en) *	1991-01-11	1993-05-04	Merck Sharpe & Dohme, Ltd.	Indazole-substituted five-membered heteroaromatic compounds
CZ283018B6 (cs) *	1991-02-01	1997-12-17	Merck Sharp And Dohme Limited	Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi
UA41297C2 (uk) *	1991-11-25	2001-09-17	Пфайзер, Інк.	Похідні індолу, фармацевтична композиція і спосіб лікування

1993
- 1993-03-04 NZ NZ251047A patent/NZ251047A/en unknown
- 1993-03-04 CA CA002132706A patent/CA2132706C/en not_active Expired - Fee Related
- 1993-03-04 US US08/295,792 patent/US5498626A/en not_active Expired - Fee Related
- 1993-03-04 CZ CZ942477A patent/CZ282653B6/cs not_active IP Right Cessation
- 1993-03-04 SK SK1207-94A patent/SK278182B6/sk unknown
- 1993-03-04 AU AU37821/93A patent/AU670270B2/en not_active Ceased
- 1993-03-04 AT AT93907096T patent/ATE148465T1/de not_active IP Right Cessation
- 1993-03-04 PL PL93305558A patent/PL172232B1/pl not_active IP Right Cessation
- 1993-03-04 EP EP93907096A patent/EP0635015B1/en not_active Expired - Lifetime
- 1993-03-04 WO PCT/US1993/001807 patent/WO1993021180A1/en active IP Right Grant
- 1993-03-04 ES ES93907096T patent/ES2097496T3/es not_active Expired - Lifetime
- 1993-03-04 KR KR1019940703551A patent/KR0179074B1/ko not_active Expired - Fee Related
- 1993-03-04 UA UA94105907A patent/UA34452C2/uk unknown
- 1993-03-04 BR BR9306221A patent/BR9306221A/pt not_active Application Discontinuation
- 1993-03-04 JP JP5518302A patent/JP2544704B2/ja not_active Expired - Fee Related
- 1993-03-04 RU RU94045902/04A patent/RU2110516C1/ru not_active IP Right Cessation
- 1993-03-04 DK DK93907096.7T patent/DK0635015T3/da active
- 1993-03-04 DE DE69307875T patent/DE69307875T2/de not_active Expired - Fee Related
- 1993-03-09 TW TW082101732A patent/TW394769B/zh active
- 1993-04-02 HR HR930753A patent/HRP930753B1/xx not_active IP Right Cessation
- 1993-04-05 IL IL105309A patent/IL105309A0/xx not_active IP Right Cessation
- 1993-04-06 MX MX9301996A patent/MX9301996A/es unknown
- 1993-04-07 EG EG21493A patent/EG20466A/xx active
- 1993-04-08 FI FI931613A patent/FI111256B/fi not_active IP Right Cessation
- 1993-04-08 ZA ZA932536A patent/ZA932536B/xx unknown
- 1993-04-08 MY MYPI93000646A patent/MY115278A/en unknown
- 1993-04-09 CN CN93104439A patent/CN1038506C/zh not_active Expired - Fee Related
- 1993-04-09 HU HU9301048A patent/HUT64060A/hu unknown
- 1993-04-09 YU YU25593A patent/YU48916B/sh unknown
1994
- 1994-10-07 NO NO943803A patent/NO309860B1/no not_active IP Right Cessation
1997
- 1997-03-07 GR GR970400451T patent/GR3022767T3/el unknown
2001
- 2001-02-05 FI FI20010214A patent/FI20010214L/fi unknown

Also Published As

Publication number	Publication date
US5498626A (en)	1996-03-12
FI931613L (fi)	1993-10-11
JP2544704B2 (ja)	1996-10-16
MX9301996A (es)	1994-03-31
CA2132706A1 (en)	1993-10-28
FI931613A0 (fi)	1993-04-08
KR0179074B1 (ko)	1999-03-20
RU2110516C1 (ru)	1998-05-10
NO943803D0 (no)	1994-10-07
CZ247794A3 (en)	1995-07-12
AU670270B2 (en)	1996-07-11
SK278182B6 (en)	1996-03-06
NZ251047A (en)	1996-09-25
EP0635015B1 (en)	1997-01-29
TW394769B (en)	2000-06-21
DE69307875D1 (de)	1997-03-13
ATE148465T1 (de)	1997-02-15
CN1038506C (zh)	1998-05-27
DK0635015T3 (da)	1997-03-17
YU25593A (sh)	1996-10-09
HRP930753A2 (en)	1994-10-31
HU9301048D0 (en)	1993-06-28
JPH07501831A (ja)	1995-02-23
NO943803L (no)	1994-10-07
DE69307875T2 (de)	1997-05-22
ZA932536B (en)	1994-10-08
MY115278A (en)	2003-05-31
EP0635015A1 (en)	1995-01-25
WO1993021180A1 (en)	1993-10-28
UA34452C2 (uk)	2001-03-15
EG20466A (en)	1999-05-31
HRP930753B1 (en)	2000-10-31
BR9306221A (pt)	1998-06-30
SK120794A3 (en)	1995-05-10
GR3022767T3 (en)	1997-06-30
FI111256B (fi)	2003-06-30
YU48916B (sh)	2002-11-15
HUT64060A (en)	1993-11-29
FI20010214L (fi)	2001-02-05
PL172232B1 (pl)	1997-08-29
CN1080288A (zh)	1994-01-05
CA2132706C (en)	1998-08-04
IL105309A0 (en)	1993-08-18
NO309860B1 (no)	2001-04-09
CZ282653B6 (cs)	1997-08-13
RU94045902A (ru)	1996-08-27
AU3782193A (en)	1993-11-18
ES2097496T3 (es)	1997-04-01

Publication	Publication Date	Title
KR950700903A (ko)	1995-02-20	5-ht1 작용물질로서의 아실아미노인돌 유도체(acylaminoindole derivatives as 5-ht1 agonists)
FI942395A0 (fi)	1994-05-24	Indolijohdannaiset
MY108909A (en)	1996-11-30	Indole derivatives
MY111683A (en)	2000-11-30	Indole derivatives.
KR960704843A (ko)	1996-10-09	5-아릴인돌 유도체 (5-arylindole derivatives)
MY109298A (en)	1996-12-31	Indole derivatives.

Legal Events

Date	Code	Title	Description
1994-10-07	A201	Request for examination
1994-10-07	PA0105	International application	Patent event date: 19941007 Patent event code: PA01051R01D Comment text: International Patent Application
1994-10-07	PA0201	Request for examination	Patent event code: PA02012R01D Patent event date: 19941007 Comment text: Request for Examination of Application
1995-02-20	PG1501	Laying open of application
1997-11-24	E902	Notification of reason for refusal
1997-11-24	PE0902	Notice of grounds for rejection	Comment text: Notification of reason for refusal Patent event date: 19971124 Patent event code: PE09021S01D
1998-01-23	AMND	Amendment
1998-02-17	E801	Decision on dismissal of amendment
1998-02-17	PE0801	Dismissal of amendment	Patent event code: PE08012E01D Comment text: Decision on Dismissal of Amendment Patent event date: 19980217 Patent event code: PE08011R01I Comment text: Amendment to Specification, etc. Patent event date: 19980123
1998-06-15	J121	Written withdrawal of request for trial
1998-06-15	PJ1201	Withdrawal of trial	Patent event code: PJ12011R01D Patent event date: 19980615 Comment text: Written Withdrawal of Request for Trial Appeal identifier: 1998102000003 Request date: 19980320 Appeal kind category: Appeal against decision to decline amendment Decision date: 19980615
1998-07-22	E601	Decision to refuse application
1998-07-22	PE0601	Decision on rejection of patent	Patent event date: 19980722 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 19971124 Comment text: Notification of reason for refusal Patent event code: PE06011S01I
1998-08-28	J201	Request for trial against refusal decision
1998-08-28	PJ0201	Trial against decision of rejection	Patent event date: 19980828 Comment text: Request for Trial against Decision on Refusal Patent event code: PJ02012R01D Patent event date: 19980722 Comment text: Decision to Refuse Application Patent event code: PJ02011S01I Appeal kind category: Appeal against decision to decline refusal Decision date: 19980930 Appeal identifier: 1998101002750 Request date: 19980828
1998-09-12	PB0901	Examination by re-examination before a trial	Comment text: Request for Trial against Decision on Refusal Patent event date: 19980828 Patent event code: PB09011R01I Comment text: Amendment to Specification, etc. Patent event date: 19980123 Patent event code: PB09011R02I
1998-09-30	B701	Decision to grant
1998-09-30	PB0701	Decision of registration after re-examination before a trial	Patent event date: 19980930 Comment text: Decision to Grant Registration Patent event code: PB07012S01D Patent event date: 19980912 Comment text: Transfer of Trial File for Re-examination before a Trial Patent event code: PB07011S01I
1998-11-26	GRNT	Written decision to grant
1998-11-26	PR0701	Registration of establishment	Comment text: Registration of Establishment Patent event date: 19981126 Patent event code: PR07011E01D
1998-11-26	PR1002	Payment of registration fee	Payment date: 19981126 End annual number: 3 Start annual number: 1
1999-03-20	PG1601	Publication of registration
2001-10-24	PR1001	Payment of annual fee	Payment date: 20011025 Start annual number: 4 End annual number: 4
2002-10-28	FPAY	Annual fee payment	Payment date: 20021029 Year of fee payment: 5
2002-10-28	PR1001	Payment of annual fee	Payment date: 20021029 Start annual number: 5 End annual number: 5
2003-11-27	LAPS	Lapse due to unpaid annual fee
2003-11-27	PC1903	Unpaid annual fee	Termination category: Default of registration fee Termination date: 20040810