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KR920011513A - 소마토트로핀 조성물 - Google Patents

소마토트로핀 조성물 Download PDF

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Publication number
KR920011513A
KR920011513A KR1019900023104A KR900023104A KR920011513A KR 920011513 A KR920011513 A KR 920011513A KR 1019900023104 A KR1019900023104 A KR 1019900023104A KR 900023104 A KR900023104 A KR 900023104A KR 920011513 A KR920011513 A KR 920011513A
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KR
South Korea
Prior art keywords
somatotropin
composition according
bovine
derivatives
somatotropin composition
Prior art date
Application number
KR1019900023104A
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English (en)
Other versions
KR0152082B1 (ko
Inventor
김남중
조흥수
이병건
Original Assignee
최근선
주식회사 럭키
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 최근선, 주식회사 럭키 filed Critical 최근선
Priority to KR1019900023104A priority Critical patent/KR0152082B1/ko
Priority to AU70937/91A priority patent/AU653325B2/en
Priority to NZ237084A priority patent/NZ237084A/en
Priority to JP3041336A priority patent/JP2620417B2/ja
Publication of KR920011513A publication Critical patent/KR920011513A/ko
Priority to US08/275,329 priority patent/US5520927A/en
Application granted granted Critical
Publication of KR0152082B1 publication Critical patent/KR0152082B1/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

내용 없음

Description

소마토트로핀 조성물
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 본 발명에 따른 우형 소마토트로핀 조성물을 투여했을 때 체중 증가 효과를 나타낸 그래프이고, 제2도는 본 발명에 따른 돼지 소마토트로핀 조성물을 투여했을 때 체중 증가 효과를 나타낸 그래프이며, 제3도는 본 발명에 따른 돼지 소마토트로핀 조성물을 투여했을 때 체중증가 효과를 나타낸 그래프.

Claims (10)

  1. 생체내 활성을 갖는 소마토트로핀을 콜린 유도체에 고르게 분산시켜 이를 1종 또는 2종이상의 초산토코페롤 또는 토코페롤 및 그 유도체와 조합하여서 이루어짐을 특징으로 하는 소마토트로핀 조성물.
  2. 제1항에 있어서, 상기 소마토트로핀은 동물의 뇌하수체로부터 추출된 것이거나 미생물에 의한 재조합 DNA 방법으로 제조된 것임을 특징으로 하는 소마토트로핀 조성물.
  3. 제1항에 있어서, 상기 소마토트로핀은 동물 성장호르몬 또는 인간 성장호르몬 임을 특징으로 하는 소마토트로핀 조성물.
  4. 제3항에 있어서, 상기 동물 성장호르몬은 우형 소마토트로핀 또는 돼지 소마토트로핀 임을 특징으로 하는 소마토트로핀 조성물.
  5. 제4항에 있어서, 상기 우형 소마토트로핀은 미생물에 의해 발현된 것임을 특징으로 하는 소마토트로핀 조성물.
  6. 제4항에 있어서, 상기 돼지 소마토트로핀은 미생물에 의해 발현된 것임을 특징으로 하는 소마토트로핀 조성물.
  7. 제1항에 있어서, 상기 소마토트로핀은 착이온 금속을 부착시킨 것이거나 부착시키지 않은 것임을 특징으로 하는 소마토트로핀 조성물.
  8. 제1항에 있어서, 상기 소마토트로핀을 제외한 나머지 성분의 합을 100중량%로 할 때 콜린유도체가 2 내지 7중량% 함유되고 초산토코페롤 또는 토코페롤 및 그 유도체가 93 내지 98중량% 함유되어 있는 것임을 특징으로 하는 소마토트로핀 조성물.
  9. 제1항에 있어서, 상기 콜린유도체는 포스파티딜콜린, 리소포스포리피드, 플라스마로겐 또는 스핀고마이엘린 임을 특징으로 하는 소마토트로핀 조성물.
  10. 제9항에 있어서, 상기 포스파티딜콜린은 대두 및 소의 간, 소의 심장, 난황 등에서 추출되어진 것임을 특징으로 하는 소마토트로핀 조성물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019900023104A 1990-02-12 1990-12-31 소마토트로핀 조성물 KR0152082B1 (ko)

Priority Applications (5)

Application Number Priority Date Filing Date Title
KR1019900023104A KR0152082B1 (ko) 1990-12-31 1990-12-31 소마토트로핀 조성물
AU70937/91A AU653325B2 (en) 1990-02-12 1991-02-11 A composition durably releasing bioactive polypeptides
NZ237084A NZ237084A (en) 1990-02-12 1991-02-11 Composition for the prolonged release of somatotropin comprising the somatotropin, a tocopherol component, and an assistant delaying agent
JP3041336A JP2620417B2 (ja) 1990-02-12 1991-02-12 生物学的活性を有するポリペプチドを持続的に放出する組成物
US08/275,329 US5520927A (en) 1990-02-12 1994-07-14 Method for the preparation of sustained release somatotropin and product produced thereby

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019900023104A KR0152082B1 (ko) 1990-12-31 1990-12-31 소마토트로핀 조성물

Publications (2)

Publication Number Publication Date
KR920011513A true KR920011513A (ko) 1992-07-24
KR0152082B1 KR0152082B1 (ko) 1998-10-15

Family

ID=19309422

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900023104A KR0152082B1 (ko) 1990-02-12 1990-12-31 소마토트로핀 조성물

Country Status (1)

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KR (1) KR0152082B1 (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100365678B1 (ko) * 2000-03-24 2002-12-26 주식회사 엘지생명과학 주사능이 개선된 소마토트로핀 조성물

Also Published As

Publication number Publication date
KR0152082B1 (ko) 1998-10-15

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