KR920007624A - 단백질 의약품의 경구투여용 조성물 - Google Patents
단백질 의약품의 경구투여용 조성물 Download PDFInfo
- Publication number
- KR920007624A KR920007624A KR1019900017011A KR900017011A KR920007624A KR 920007624 A KR920007624 A KR 920007624A KR 1019900017011 A KR1019900017011 A KR 1019900017011A KR 900017011 A KR900017011 A KR 900017011A KR 920007624 A KR920007624 A KR 920007624A
- Authority
- KR
- South Korea
- Prior art keywords
- composition
- oral administration
- protein
- polyoxyethylene
- protein pharmaceuticals
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Claims (8)
- 의약품의 경구투여용 조성물에 있어서, 초산 토코페롤과 흡수촉진제 및 생물학적 활성을 갖는 단백질 의약품을 함유하는 것을 특징으로 하는 단백질 의약품의 경구투여용 조성물.
- 제1항에 있어서, 상기 흡수촉진제는 폴리옥시에틸렌 유도체, 살리실산과 그 유도체, 담즙산과 그 유도체, 라우릴 황산 나트륨, 타우로디히드로푸시딘산 나트륨, 킬레이트화제 및 계면활성제 중에서 선택된 1종 또는 2종 이상의 혼합물인 것임을 특징으로 하는 단백질 의약품의 경구투여용 조성물.
- 제2항에 있어서, 상기 폴리옥시에틸렌 유도체는 폴리옥시에틸렌 20 세틸 에테르 또는 폴리옥시에틸렌 20 올레일 에테르인 것임을 특징으로 하는 단백질 의약품의 경구투여용 조성물.
- 제1항 또는 제2항에 있어서, 상기 흡수촉진제는 초산 토코페롤 100중량부에 대해 0.1 내지 20중량부의 양으로 함유된 것임을 특징으로 하는 단백질 의약품의 경구투여용 조성물.
- 제1항에 있어서, 상기 단백질 의약품은 인슐린, 인터페론, 성장호르몬, 인터루킨-2, 종양괴사인자, 콜로니자극인자 또는 그 유사품인 것임을 특징으로 하는 단백질 의약품의 경구투여용 조성물.
- 제5항에 있어서, 상기 인터페론이 γ-인터페론임을 특징으로 하는 단백질 의약품 경구투여용 조성물.
- 제1항에 있어서, 상기 조성물에는 단백질 분해효소 저해제가 함유되어 있는 것임을 특징으로 하는 단백질 의약품의 경구투여용 조성물.
- 제7항에 있어서, 상기 단백질 분해효소 저해제는 아프로티닌인 것임을 특징으로 하는 단백질 의약품의 경구투여용 조성물.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019900017011A KR930002093B1 (ko) | 1990-10-24 | 1990-10-24 | 단백질 의약품의 경구투여용 조성물 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019900017011A KR930002093B1 (ko) | 1990-10-24 | 1990-10-24 | 단백질 의약품의 경구투여용 조성물 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR920007624A true KR920007624A (ko) | 1992-05-27 |
| KR930002093B1 KR930002093B1 (ko) | 1993-03-26 |
Family
ID=19305093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019900017011A KR930002093B1 (ko) | 1990-10-24 | 1990-10-24 | 단백질 의약품의 경구투여용 조성물 |
Country Status (1)
| Country | Link |
|---|---|
| KR (1) | KR930002093B1 (ko) |
-
1990
- 1990-10-24 KR KR1019900017011A patent/KR930002093B1/ko not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR930002093B1 (ko) | 1993-03-26 |
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