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KR910014398A - 항생제 데옥시물룬도칸딘, 이의 제조방법 및 약제로서의 이의 용도 - Google Patents

항생제 데옥시물룬도칸딘, 이의 제조방법 및 약제로서의 이의 용도 Download PDF

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KR910014398A
KR910014398A KR1019910001162A KR910001162A KR910014398A KR 910014398 A KR910014398 A KR 910014398A KR 1019910001162 A KR1019910001162 A KR 1019910001162A KR 910001162 A KR910001162 A KR 910001162A KR 910014398 A KR910014398 A KR 910014398A
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South Korea
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medicament
culture
cultured
compound according
deoxymulundocandine
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KR1019910001162A
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KR0172949B1 (ko
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로이 키리티
무코패디에이 트립티쿠마
펠하버 한스-볼프람
코글러 헤르베르트
나레시 간굴리 바이맬
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펜스케, 라피세
훽스트 아크티엔게젤샤프트
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

내용 없음

Description

항생제 데옥시물룬도칸딘, 이의 제조방법 및 약제로서의 이의 용도
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 데옥시물룬도칸딘의 IR스펙트럼(KBr)이다.

Claims (10)

  1. 구조식(Ⅰ)의 데옥시물룬도칸딘 화합물, 이의 화학적 등가물, 또는 이의 생리학적으로 허용되는 유도체.
  2. 아스퍼길러스 시도위(Aspergillus sydowil)Y-30462(DSM 5745)를 탄소원, 질소원 및 무기염을 함유하는 영양 배지중에서 호기성 조건하에 배양함을 특징으로 하여, 제1항에 따른 화합물을 제조하는 방법.
  3. 제2항에 있어서, 25℃내지 30℃의 온도에서 배양하는 방법.
  4. 제2항 또는 3항에 있어서, pH6내지 7에서 배양하는 방법.
  5. 제2항 내지 4항중 어느 한 항에 있어서, 약 26℃의 온도 및 약 pH6.5에서 배양하는 방법.
  6. 제2항 내지 5항중 어느 한 항에 있어서, 66시간이상 동안 배양하는 방법.
  7. 제2내지 6항중 어느 한 항에 있어서, 액침 배양법으로 배양하는 방법.
  8. 제1항에 따른 화합물을 필요한 경우 통상의 보조제 및/또는 비이클과 함께 함유하는 약제.
  9. 항효모작용, 항진균성작용 및/또는 면역조절 작용을 갖는 약제를 제조하기 위한 제1항에 따른 화합물의 용도.
  10. 아스퍼길러스 시도위 배양물 제Y-30462호.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019910001162A 1990-01-26 1991-01-24 항생제 데옥시물룬도칸딘, 이의 제조방법 및 이를 함유하는 약제 Expired - Lifetime KR0172949B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP90101538 1990-01-26
EP90101538.8 1990-01-26

Publications (2)

Publication Number Publication Date
KR910014398A true KR910014398A (ko) 1991-08-31
KR0172949B1 KR0172949B1 (ko) 1999-02-01

Family

ID=8203542

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019910001162A Expired - Lifetime KR0172949B1 (ko) 1990-01-26 1991-01-24 항생제 데옥시물룬도칸딘, 이의 제조방법 및 이를 함유하는 약제

Country Status (18)

Country Link
US (1) US5387670A (ko)
EP (1) EP0438813B1 (ko)
JP (1) JP3156232B2 (ko)
KR (1) KR0172949B1 (ko)
AT (1) ATE160357T1 (ko)
AU (1) AU644838B2 (ko)
CA (1) CA2034979C (ko)
DE (1) DE69031730T2 (ko)
DK (1) DK0438813T3 (ko)
ES (1) ES2110405T3 (ko)
FI (1) FI95602C (ko)
GR (1) GR3025607T3 (ko)
IE (1) IE910270A1 (ko)
IL (1) IL97040A (ko)
NO (1) NO179755C (ko)
NZ (1) NZ236888A (ko)
PT (1) PT96564B (ko)
ZA (1) ZA91570B (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6613738B1 (en) * 1998-08-10 2003-09-02 Hmv Corporation Cyclic lipopeptide from Cryptosporiopsis quercina possessing antifungal activity
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US20060014674A1 (en) * 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
EP2504353B2 (en) 2009-11-23 2023-09-13 Cubist Pharmaceuticals LLC Lipopeptide compositions and related methods
CN103074234B (zh) * 2012-12-25 2015-03-04 浙江工业大学 一株海洋真菌萨氏曲霉及其在制备抗肿瘤药物中的应用
CN112680360B (zh) * 2021-01-11 2021-10-15 青海师范大学 一株聚多曲霉菌及促进植物生长和防治植物病害的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1182812A (en) * 1979-12-13 1985-02-19 Bernard J. Abbott Process for the preparation of derivatives of cyclic peptide nuclei

Also Published As

Publication number Publication date
FI95602C (fi) 1996-02-26
NO910309D0 (no) 1991-01-25
ES2110405T3 (es) 1998-02-16
IL97040A0 (en) 1992-03-29
FI910366A0 (fi) 1991-01-24
DE69031730T2 (de) 1998-04-23
KR0172949B1 (ko) 1999-02-01
DE69031730D1 (de) 1998-01-02
EP0438813A1 (en) 1991-07-31
NO910309L (no) 1991-07-29
AU644838B2 (en) 1993-12-23
JP3156232B2 (ja) 2001-04-16
IL97040A (en) 1995-03-30
PT96564B (pt) 1998-07-31
FI910366L (fi) 1991-07-27
JPH0530986A (ja) 1993-02-09
DK0438813T3 (da) 1998-07-27
NO179755B (no) 1996-09-02
FI95602B (fi) 1995-11-15
IE910270A1 (en) 1991-07-31
GR3025607T3 (en) 1998-03-31
ZA91570B (en) 1991-11-27
EP0438813B1 (en) 1997-11-19
NO179755C (no) 1996-12-11
CA2034979A1 (en) 1991-07-27
AU6998691A (en) 1991-08-01
CA2034979C (en) 2001-01-02
NZ236888A (en) 1993-03-26
US5387670A (en) 1995-02-07
PT96564A (pt) 1991-10-15
ATE160357T1 (de) 1997-12-15

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