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KR910000650A - 사이클릭 안트라닐산 아세트산 유도체 및 이의 제조방법 - Google Patents

사이클릭 안트라닐산 아세트산 유도체 및 이의 제조방법 Download PDF

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Publication number
KR910000650A
KR910000650A KR1019900008583A KR900008583A KR910000650A KR 910000650 A KR910000650 A KR 910000650A KR 1019900008583 A KR1019900008583 A KR 1019900008583A KR 900008583 A KR900008583 A KR 900008583A KR 910000650 A KR910000650 A KR 910000650A
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South Korea
Prior art keywords
formula
acid
compound
carbon atoms
alkyl group
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KR1019900008583A
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English (en)
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KR960007084B1 (ko
Inventor
미츠토모 미야시타
야수시 고노
에이스케 고지마
고지 사이토
Original Assignee
하기하라 시게루
교린 세이야쿠 가부시키가이샤
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Publication of KR910000650A publication Critical patent/KR910000650A/ko
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Publication of KR960007084B1 publication Critical patent/KR960007084B1/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C07D215/06—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

내용 없음

Description

사이클릭 안트라닐산 아세트산 유도체 및 이의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (17)

  1. 하기 일반식(Ⅰ)의 사이클릭 안트라닐산 아세트산 유도체 및 이의 산 또는 알칼리 염.
  3. 상기식에서, R1및 R2는 각기 독립적으로 수소원자, 탄소수 1내지 3의 저급 알킬 그룹을 나타낸다.
  4. 하기 일반식(Ⅱ)의 화합물을 가수분해시킨 다음 산화제의 존재하에 탈카보닐화시킴을 특징으로 하여, 하기 일반식(Ⅰ)의 화합물 및 이의 산 또는 알칼리 염을 제조하는 방법.
  7. 상기식에서, R,R1, 및 R2는 각기 독립적으로 수소원자, 탄소수 1내지 3의 저급 알킬 그룹을 나타낸다.
  8. 하기 일반식(Ⅰ)의 화합물 또는 이의 산 또는 알칼리 염 및 약제학적으로 허용되는 불활성 담체를 함유하는 자기면역성 질환을 치료하기 위한 약제.
  10. 상기식에서, R1및 R2는 각기 독립적으로 수소원자, 탄소수 1내지 3의 저급 알킬 그룹을 나타낸다.
  11. 하기 일반식(Ⅰ)의 화합물 또는 이의 산 또는 알칼리 염 및 약제학적으로 허용되는 불활성 담체를 함유하는 항류마티스제.
  13. 상기식에서, R1및 R2는 각기 독립적으로 수소원자, 탄소수 1내지 3의 저급 알킬 그룹을 나타낸다.
  14. 하기 일반식(Ⅰ)의 화합물 또는 이의 산 또는 알칼리 염 및 약제학적으로 허용되는 불활성 담체를 함유하는 대사성 뼈 질환을 치료하기 위한 치료학적 또는 예방학적 제제.
  16. 상기식에서, R1및 R2는 각기 독립적으로 수소원자, 탄소수 1내지 3의 저급 알킬 그룹을 나타낸다.
  17. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019900008583A 1989-06-13 1990-06-12 사이클릭 안트라닐산 아세트산 유도체, 이의 제조방법 및 이를 함유하는 약제 Expired - Fee Related KR960007084B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP149989/1989 1989-06-13
JP1-149989 1989-06-13
JP1149989A JPH0317061A (ja) 1989-06-13 1989-06-13 新規環状アントラニル酸酢酸誘導体

Publications (2)

Publication Number Publication Date
KR910000650A true KR910000650A (ko) 1991-01-29
KR960007084B1 KR960007084B1 (ko) 1996-05-27

Family

ID=15487033

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900008583A Expired - Fee Related KR960007084B1 (ko) 1989-06-13 1990-06-12 사이클릭 안트라닐산 아세트산 유도체, 이의 제조방법 및 이를 함유하는 약제

Country Status (9)

Country Link
US (1) US5120743A (ko)
EP (1) EP0402862B1 (ko)
JP (1) JPH0317061A (ko)
KR (1) KR960007084B1 (ko)
CN (1) CN1034572C (ko)
AU (1) AU623018B2 (ko)
CA (1) CA2018834A1 (ko)
DE (1) DE69031409D1 (ko)
HU (1) HU208424B (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6180640B1 (en) 1998-06-25 2001-01-30 Sepracor, Inc. Di- and tetra-hydroquinoline-indole antimicrobial agents, uses and compositions related thereto
JP2014092526A (ja) 2012-11-07 2014-05-19 Mitsubishi Electric Corp 磁気検出装置

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2042352A1 (fr) * 1969-04-21 1971-02-12 Ciba Geigy Ag Acides alpha-(1,2,3,4-tetrahydro-6-quinolyl)-carboxyliques et leurs derives
JPS5463002A (en) * 1977-10-28 1979-05-21 Mitsubishi Gas Chem Co Inc Preparation of carboxylic acids and phenol carboxylic acid esters
JPS58116466A (ja) * 1981-12-29 1983-07-11 Nippon Zoki Pharmaceut Co Ltd 新規キノリル酢酸誘導体及び該化合物を含有する医薬組成物
US4960892A (en) * 1988-06-10 1990-10-02 American Home Products Corporation Naphthalenepropionic acid derivatives as anti-inflammatory/anti-allergic agents
US4956372A (en) * 1987-10-02 1990-09-11 Kyorin Pharmaceutical Co., Ltd. Cyclic anthranilic acid derivatives and process for their preparation
AU612181B2 (en) * 1987-10-02 1991-07-04 Kyorin Pharmaceutical Co. Ltd. Novel cyclic anthranilic acid derivatives and process for their preparation
US4809020A (en) * 1987-12-28 1989-02-28 Polaroid Corporation Control apparatus for electronic image printer

Also Published As

Publication number Publication date
HU208424B (en) 1993-10-28
CN1048034A (zh) 1990-12-26
HUT54659A (en) 1991-03-28
EP0402862A2 (en) 1990-12-19
KR960007084B1 (ko) 1996-05-27
JPH0317061A (ja) 1991-01-25
EP0402862A3 (en) 1991-10-16
CN1034572C (zh) 1997-04-16
AU5702990A (en) 1990-12-20
AU623018B2 (en) 1992-04-30
HU903791D0 (en) 1990-11-28
EP0402862B1 (en) 1997-09-10
CA2018834A1 (en) 1990-12-13
US5120743A (en) 1992-06-09
DE69031409D1 (de) 1997-10-16

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