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KR870001225A - (티오노)포스포르산 에스테르의 제조방법 - Google Patents

(티오노)포스포르산 에스테르의 제조방법 Download PDF

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Publication number
KR870001225A
KR870001225A KR1019860005414A KR860005414A KR870001225A KR 870001225 A KR870001225 A KR 870001225A KR 1019860005414 A KR1019860005414 A KR 1019860005414A KR 860005414 A KR860005414 A KR 860005414A KR 870001225 A KR870001225 A KR 870001225A
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KR
South Korea
Prior art keywords
alkyl
optionally substituted
pyrimidin
iii
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1019860005414A
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English (en)
Inventor
마우러 프리쯔
Original Assignee
칼-루드비히 슈미트, 에리히-데브리쯔
바이엘 아크티엔게젤샤프트
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Application filed by 칼-루드비히 슈미트, 에리히-데브리쯔, 바이엘 아크티엔게젤샤프트 filed Critical 칼-루드비히 슈미트, 에리히-데브리쯔
Publication of KR870001225A publication Critical patent/KR870001225A/ko
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/16—Esters of thiophosphoric acids or thiophosphorous acids
    • C07F9/165—Esters of thiophosphoric acids
    • C07F9/18—Esters of thiophosphoric acids with hydroxyaryl compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

내용 없음.

Description

(티오노)포스포르산 에스테르의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (10)

  1. 하기 일반식(II)의 하이드록실 유도체 또는 이의 적절한 암모늄염, 알칼리금속염 또는 알칼리 토금속염을 촉매로서 비사이클릭 유기 아민의 존재하에 필요시 산 수용체의 존재하에 및 희석제의 존재하에 0 내지 120℃에서 하기 일반식(III)의 (티오노)포스포릭 할라이드와 반응시킴을 특징으로 하여 하기 일반식(I)의 (티오노)포스포르산 에스테르를 제조하는 방법.
    상기 식에서, X는 산소 또는 황이고, R 및 R1은 동일하거나 상이하며 알킬을 나타내고, R2는 임의로 치환된 아릴이거나 하나 이상의 질소원자를 갖는 임의로 치환된 헤트아릴이며, Hal은 할로겐이다.
  2. 제1항에 있어서, 일반식(I),(II) 및 (III)에서 X가 산소 또는 황이고, R 및 R1이 동일하거나 상이하며 C1내지 C6알킬을 나타내고, R2가 불소, 염소, 브롬, 니트로, 시아노, C1내지 C4알킬, C1내지 C4알콕시, 페닐 C1내지 C4알킬티오, 할로게노-C1내지 C4알킬, 할로게노-C1내지 C4알콕시, 할로게노-C1내지 C4알킬티오 C1내지 C4알킬-설피닐, C1내지 C4알킬설포닐, C1내지 C2 알킬설피닐 -C1내지 C4알킬, C1내지 C2 알킬설포닐 C1내지 C4알킬 및/또는 C1내지 C4알콕시카보닐에 의해 1 내지 3번 임의로 치환된 페닐; 염소, 브롬, C1내지 C4알킬, C1내지 C4알콕시, C1내지 C4알킬티오, C3내지 C6사이클로알킬, 페닐, 디-(C1내지 C4)알킬아미노, C1내지 C2알콕시 -C1내지 C4알킬, C1내지 C2알킬티오-C1내지 C4알킬, C1내지 C2알킬티오-C1내지 C4알콕시, C1내지 C2-알킬설피닐 -C1내지 C4알킬 및 또는 C1내지 C2알킬설포닐 -C1내지 C4알킬에 의해 1 내지 3번 임의로 치환된 피리미딘 -2-일, 피리미딘-4-일 또는 피리미딘-5-일; C1내지 C4알킬 및 또는 페닐에 의해 1 또는 2번 임의로 치환된 1,2,4-트리아졸-3-일; 및 염소, 브롬 및 또는 할로게노-C1내지 C2알킬에 의해 1 내지 3번 임의로 치환된 피리드-2-일을 나타내고, Hal이 염소를 나타내는 방법.
  3. 제1항에 있어서, 일반식(I),(II) 및 (III)에서 X가 산소 또는 황이고, R 및 R1이 동하거나 상이하며 C1내지 C4알킬(바람직하게는, 에틸 또는 i-프로필)을 나타내고, R2가 4-니트로페닐, 피리미딘-2-일, 5-브로모-피리미딜-2-일, 5-3-급-부틸-피리미딘-2-일, 2-i-프로필-4-메틸-피리미딘-6-일 또는 2,3,5-트리클로로피리딘-6-일이며, Hal이 염소를 나타내는 방법.
  4. 제1 내지 3항중 어느 한 항에 있어서, 일반식(I) 및 (III)에서 X가 황인 방법.
  5. 제1항 내지 3항중 어느 한 항에 있어서, 일반식(I),(II) 및 (III)에서 X가 황이고, R이 에틸이며, R1이 i-프로필이고, R2가 5-3-급-부틸-피리미딘-2-일이며 Hal이 염소인 방법.
  6. 제1항 내지 5항중 어느 한 항에 있어서, 반응을 20 내지 100℃에서 수행하는 방법.
  7. 제1항 내지 6항중 어느 한 항에 있어서, 일반식(II)의 하이드록실 화합물 1mole당 0.8 내지 1.5mole의 일반식(III)의 화합물을 사용하는 방법.
  8. 제1항 내지 7항중 어느 한 항에 있어서, 일반식(II)의 화합물 1mole당 0.005 내지 0.5mole의 비사이클릭 유기아민을 촉매로서 사용하는 방법.
  9. 제1항 내지 8항중 어느 한 항에 있어서, 비사이클릭 유기아민으로서 1,4-디아자비사이클로-(2,2,2)-옥탄(DABCO)을 사용하는 방법.
  10. 제1항 내지 9항중 어느 한 항에 있어서, 산수용체로서 탄산칼륨을 사용하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019860005414A 1985-07-05 1986-07-04 (티오노)포스포르산 에스테르의 제조방법 Withdrawn KR870001225A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19853524055 DE3524055A1 (de) 1985-07-05 1985-07-05 Verfahren zur herstellung von (thiono)phosphorsaeureestern
DEP3524055.5 1985-07-05

Publications (1)

Publication Number Publication Date
KR870001225A true KR870001225A (ko) 1987-03-12

Family

ID=6275033

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019860005414A Withdrawn KR870001225A (ko) 1985-07-05 1986-07-04 (티오노)포스포르산 에스테르의 제조방법

Country Status (11)

Country Link
US (1) US4772702A (ko)
EP (1) EP0207412B1 (ko)
JP (1) JPS6277395A (ko)
KR (1) KR870001225A (ko)
AT (1) ATE51625T1 (ko)
BR (1) BR8603137A (ko)
DD (1) DD248123A5 (ko)
DE (2) DE3524055A1 (ko)
DK (1) DK166543C (ko)
HU (1) HUT42777A (ko)
IL (1) IL79322A (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3524055A1 (de) * 1985-07-05 1987-01-08 Bayer Ag Verfahren zur herstellung von (thiono)phosphorsaeureestern

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1525066A (fr) * 1965-12-18 1968-05-17 Dynamit Nobel Ag Procédé de préparation d'esters halogénés d'acides phosphoriques
US4092312A (en) * 1975-07-31 1978-05-30 The Dow Chemical Company Process for preparing phosphorothioates and phenylphosphonothioates
JPS5920680B2 (ja) * 1975-08-04 1984-05-15 ザ ダウ ケミカル カンパニ− ホスホロチオエ−トまたはフエニルホスホロチオエ−トを製造する方法
NL186814C (nl) * 1975-08-07 1991-03-01 Dow Chemical Co Werkwijze ter bereiding van een fosforthioaat of fenylfosfonothioaat.
US4357328A (en) * 1979-10-15 1982-11-02 The Dow Chemical Co. Heterocyclic substituted triazolyl phosphorous compounds and their use as insecticides
DE3524055A1 (de) * 1985-07-05 1987-01-08 Bayer Ag Verfahren zur herstellung von (thiono)phosphorsaeureestern

Also Published As

Publication number Publication date
DK318386D0 (da) 1986-07-04
DK166543C (da) 1993-10-25
DK166543B (da) 1993-06-07
DD248123A5 (de) 1987-07-29
HUT42777A (en) 1987-08-28
DE3524055A1 (de) 1987-01-08
DK318386A (da) 1987-01-06
DE3670084D1 (de) 1990-05-10
ATE51625T1 (de) 1990-04-15
US4772702A (en) 1988-09-20
EP0207412A2 (de) 1987-01-07
IL79322A (en) 1990-12-23
BR8603137A (pt) 1987-02-24
JPS6277395A (ja) 1987-04-09
EP0207412A3 (en) 1988-08-03
EP0207412B1 (de) 1990-04-04
IL79322A0 (en) 1986-10-31

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Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19860704

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