KR20130086553A - Detergent composition for clothes washing - Google Patents

Abstract

An object of this invention is to provide the medical detergent composition which can fully prevent the fall of the hue and whiteness of the finishing of textile products, such as a garment after washing.
As a means for this,
(A) sodium percarbonate,
(B) hydrogen carbonate alkali metal salt,
(C) alkali metal carbonate salt,
(D) aluminosilicates, and
(E) surfactant
As a medical detergent composition containing the, content of (B) component is 20 mass% or more with respect to the gross mass of the composition, content of (D) component is 10 mass% or less with respect to the gross mass of the composition, , the weight ratio of bicarbonate to carbonate sogeun muscle _{^{(HCO 3 - / CO 3 2}} -) is provided for 0.9 or more, the medical detergent compositions.

Description

Medical detergent composition {DETERGENT COMPOSITION FOR CLOTHES WASHING}

TECHNICAL FIELD This invention relates to the medical detergent composition used for textile products, such as a garment and a towel. Specifically, it relates to the medical detergent composition which can fully prevent the fall of the hue and whiteness of the finish of textile products, such as a garment after washing.

Until now, various medical detergent compositions have been proposed. Conventionally, in order to improve the cleaning power of a medical detergent composition, to maintain the whiteness of wash | cleaned clothing, and to reduce a bad smell, it has been mainly performed to examine the compounding component of a medical detergent composition, paying attention to dropping the dirt of a garment.

For example, Patent Document 1 describes a high bulk density detergent containing a combination of a specific surfactant, a fluorescent brightener and a hydrocarbonate. Patent document 2 describes a solid laundry detergent composition containing a combination of specific surfactants, zeolites and phosphates. Patent document 3 describes a bleaching composition containing a copper compound, a zinc compound, hydrogen peroxide or a peroxide that releases hydrogen peroxide in water, a chirate compound, a surfactant, and a perfume.

Patent Document 1: Japanese Patent Application Laid-Open No. 2001-152198 Patent Document 2: Japanese Patent Application Laid-Open No. 2008-530272 Patent Document 3: Japanese Patent Application Laid-Open No. 2011-57745

In recent years, however, there have been changes in the washing environment, such as the increase in the size of washing machines, the spread of drum washing machines, the saving of water and immersion washing in consideration of the environment and saving. In connection with this, in the conventional general detergent product, the fall of the color tone and whiteness of the finish of the wash | cleaned clothing arises a subject.

Therefore, the medical detergent composition which can fully prevent the fall of the hue and whiteness of the finishing of the garment after washing responding to such a recent washing | cleaning environment change is needed.

In the present invention, paying attention to the dullness of the washing liquid (filtrate in the washing liquid) generated when washing textile products such as clothing, blended by combining sodium percarbonate and alkali hydrogen carbonate metal salt, and making it a specific hydrogen carbonate / carbonate ratio It was confirmed that when the washing liquid was dull and when the fluorescent agent was blended, the effect of the fluorescent agent could be enhanced and the above problems could be solved.

Sodium percarbonate is a substance which releases hydrogen peroxide in water and exhibits a bleaching action, and it is known that the higher the pH of the aqueous solution has a good bleaching action, since the pKa (acid dissociation constant) of hydrogen peroxide is 11.7. On the other hand, when the alkali metal carbonate salt is added to the aqueous sodium percarbonate solution, since the pH of the aqueous solution is lowered, it is generally considered that the bleaching action by sodium percarbonate tends to decrease. Therefore, in the medical detergent composition, the combination combining sodium percarbonate and alkali hydrogen carbonate metal salt was not expected to exert an excellent effect on the color tone, whiteness, and the like of the finish of textile products such as laundry after washing.

However, the present inventors, in the medical detergent composition, by combining sodium percarbonate and alkali hydrogen carbonate metal salts, and by using a specific hydrogen carbonate / carbonate ratio to improve the dullness of the washing liquid, and further formulated a fluorescent agent In this case, it was confirmed that an unexpected effect is caused that the effect of the fluorescent agent can be enhanced.

By the way, although the above-mentioned patent document 3 describes the composition which mix | blended and combined sodium percarbonate and the alkali metal carbonate salt in the Example, neither does it satisfy | fill the structure of the following this invention. In addition, the invention described in Patent Document 3 is characterized in that the fragrance can be imparted with excellent reverberation, and Patent Document 3 is capable of improving the dullness of the washing liquid and further formulating a fluorescent agent. In this case, no disclosure or suggestion is made as to whether the effect of the fluorescent agent can be enhanced.

According to the present invention,

(A) sodium percarbonate,

(B) hydrogen carbonate alkali metal salt,

(C) alkali metal carbonate salt,

(D) aluminosilicates and

(E) surfactant

As a medical detergent composition containing the, content of (B) component is 20 mass% or more with respect to the gross mass of the composition, content of (D) component is 10 mass% or less with respect to the gross mass of the composition, , the weight ratio of bicarbonate to carbonate sogeun muscle _{^{(HCO 3 - / CO 3 2}} -) is provided for 0.9 or more, the medical detergent compositions.

In addition, the present invention, in addition to the components (A) to (E), is further selected from (F) anionic water-soluble and / or semi-dispersible fluorescent brighteners and water-insoluble blue pigments. Or a medical detergent composition containing two or more kinds.

Moreover, in another yangtan, this invention provides the medical detergent composition which contains (G) cellulase further in addition to said (A)-(E) component or said (A)-(F) component.

According to the detergent composition for medical treatment of the present invention, even in washing environments such as water washing machine, expansion of drum washing machine, saving water and immersion washing conscious of environment and saving, reduction of color tone and whiteness of finish of textile products such as clothes after washing It can be prevented enough.

[Component (A)] [

(A) component used by the medical detergent composition of this invention is sodium percarbonate. By compounding sodium percarbonate, it is possible to reduce the dullness (L ^* value, b ^* value) of the solution due to the dirt from the washing liquid at the time of washing, and also by increasing the absolute value of the zeta potential of the dirt and fibers, Reattachment to the fiber can be suppressed.

In the medical detergent composition of the present invention, sodium percarbonate may be blended as it is, or coated sodium percarbonate particles coated with particles of sodium percarbonate may be blended. By using the coated sodium percarbonate particles, the stability of sodium percarbonate during storage can be improved.

As the coated sodium percarbonate particles, known ones can be used. For example, those coated with silicic acid and / or silicate and boric acid and / or borate, or those coated with a combination of an inorganic compound and a surfactant such as LAS are preferable. Specifically, as described in Japanese Patent No. 2918991 or the like, the coating is applied by spraying silicic acid and / or alkali silicate aqueous solution and boric acid and / or boric acid alkali metal salt aqueous solution or the like, or described in Japanese Patent No. 2871298. And those coated with an aromatic hydrocarbon sulfonic acid and / or an alkali silicate salt having an average particle diameter of 10 to 500 µm, a carbonate, a bicarbonate, a sulfate, or the like, or a coating with a water-insoluble organic compound such as paraffin or wax. For nonhazardization, the coated sodium percarbonate particles may be used in powder blends with various inorganic materials such as sodium carbonate and sodium hydrogencarbonate.

Sodium percarbonate and coated sodium percarbonate particles may be commercially available. For example, SPCC (Zhejiang Jinke Chemicals Co., Ltd.), Sodium Percarbonate (Zhejiang DC Chemical Co., Ltd.), PC-W (Japan Peroxide), etc. are suitable. Can be.

In the medical detergent composition of this invention, when mix | blending coated sodium percarbonate particle | grains as (A) component, 200-1000 micrometers is preferable and, as for the average particle diameter of the particle | grains, 500-1000 micrometers is more preferable. Moreover, in order to improve solubility and stability, it is preferable that the particle | grains whose particle diameters are less than 125 micrometers, and the particle | grains exceeding 1400 micrometers are 10 mass% or less in the particle | grains.

In addition, in this specification, an "average particle diameter" is a value calculated | required by the following measuring method.

`` Measurement method of average particle diameter ''

First, regarding the measurement object (sample), a 9-stage mesh and dish plate of 1680 µm, 1410 µm, 1190 µm, 1000 µm, 710 µm, 500 µm, 350 µm, 250 µm and 149 µm Classification is performed. In the classification operation, first, the 9-stage sieve is stacked above the receiving plate so that the net size gradually increases, and 100 g / time sample is put on the top of the sieve having a net size of 1680 µm. Subsequently, the lid was covered and attached to a low-top sieve shaker (manufactured by Iida Manufacturing Co., Ltd., Tapping: 156 times / minute, Rolling: 290 times / minute), vibrated for 10 minutes, and the samples remaining on the respective sieves and dish plates. Is collected for every eye and the mass of the sample is measured. The mass frequency of the dish plate and each sieve is integrated, and the mesh size of the first sieve whose cumulative mass frequency is 50% or more is set to a µm, and the mesh size of the sieve one step larger than a µm is set to b µm. By setting the mass frequency of the mass from the dish to the sieve of a μm and the mass frequency on the sieve of a μm to d%, the average particle diameter (mass 50%) is given by the following formula (1). Obtain

As for the compounding quantity of (A) component, 2-20 mass% is preferable with respect to the gross mass of the medical detergent composition from a viewpoint of prevention of reattachment of a dirt, and the effect improvement of the following (F) component, and 3-15 mass% More preferred. If the compounding quantity of (A) component is 2 mass% or more, sufficient effect can be exhibited, and when it exceeds 20 mass%, reattachment prevention ability may be saturated, and it may not be efficient.

[Component (B)] [

(B) component used by the medical detergent composition of this invention is an alkali metal hydrogencarbonate. By mix | blending an alkali metal carbonate salt, the effect of the said (A) component can be improved further. This effect is not expressed even if it substitutes with inorganic salts other than the alkali metal carbonate salt (for example, sodium sulfate or sodium carbonate).

In the medical detergent composition of the present invention, examples of the alkali metal carbonate salt that can be blended as the component (B) include sodium hydrogen carbonate, potassium hydrogen carbonate, sodium sesquicarbonate, and the like. Among them, sodium hydrogen carbonate is preferable. These (B) components can be used individually by 1 type or in combination of 2 or more types.

Although the particle diameter of (B) component is not specifically limited, For example, an average particle diameter of 10-1000 micrometers is preferable and 150-350 micrometers is more preferable. When it is 10 micrometers or more, the powderiness in the manufacturing process of a granular detergent composition is suppressed, and when it is 1000 micrometers or less, solubility to water at the time of use is favorable. In addition, the average particle diameter of a component (B) is a value obtained by said measuring method similarly to the average particle diameter of a component (A).

Although the particle size distribution of (B) component is not specifically limited, It is preferable that the particle | grains of 600 micrometers or more of particle diameters are not substantially contained. By not containing such particles, the solubility is further improved, and the effect of the present invention is improved.

Moreover, it is preferable that the particle | grains of 150 micrometers or more of particle | grains (B) are less than 20 mass% in the component (B), and it is more preferable that it is less than 10 mass%. If the particle | grains whose particle diameter is less than 150 micrometers are less than 20 mass%, solidification of the particle | grains in a granular detergent composition will be easy to be suppressed favorably.

The compounding quantity of (B) component is 20 mass% or more with respect to the gross mass of the medical detergent composition, for example, and is 40 mass% or less. From a viewpoint of the effect improvement of the said (A) component, 20-35 mass% is preferable, and 25-30 mass% is more preferable. If it is less than 20 mass%, the dullness improvement of a washing | cleaning liquid may not be fully acquired, and reattachment may arise easily, and when it exceeds 35 mass%, the dullness improvement effect may be saturated.

The preferred ratio (mass ratio) of (A) / (B) is 0.06 to 1.00, more preferably 0.20 to 1.00. If it is in this range, the effect of the fluorescent agent which is especially the following (F) component will become favorable.

[Component (C)] [

(C) component used by the medical detergent composition of this invention is an alkali metal carbonate, for example, sodium carbonate and potassium carbonate.

As for the compounding quantity of (C) component, 10-30 mass% is preferable with respect to the gross mass of the medical detergent composition. If it is 10 mass% or more, sufficient washing power can be exhibited, and when it exceeds 30 mass%, powder physical property may fall.

The weight ratio of bicarbonate to carbonate sogeun muscle in the detergent compositions of the present invention for medical use _{^{(HCO 3 - / CO 3 2}} -) is at least 0.9, more preferably from 1.0 1.5. If it exists in this range, especially the effect of improving the dullness of a washing | cleaning liquid will become favorable, and the finishing of clothing etc. will also become especially favorable.

[Component (D)] [

(D) component used by the medical detergent composition of this invention is an aluminosilicate. By blending aluminosilicates, good powder physical properties can be provided.

As the aluminosilicate, any of crystalline and amorphous (amorphous) can be used. As crystalline aluminosilicate, zeolite can be mix | blended suitably, and any of A type, X type, Y type, and P type can be used as the zeolite.

From the viewpoint of improving the physical properties such as cleaning power, fluidity and the dullness of the cleaning liquid, the blending amount of the component (D) is preferably 1% by mass or more and 10% by mass or less, based on the total mass of the medical detergent composition. Mass% or less is more preferable, and 2 mass% or more and 6 mass% or less are especially preferable at the point of color tone maintenance, such as clothing.

The preferable ratio (mass ratio) of (D) / (B) is 0.03-0.50, More preferably, it is 0.03-0.30. If it is in this range, it is especially preferable at the point of color tone maintenance, such as clothing.

[(E) component]

(E) component used by the medical detergent composition of this invention is surfactant. In the medical detergent composition of this invention, as (E) component, anionic surfactant, a nonionic surfactant, a cationic surfactant, and an amphoteric surfactant can be used individually by 1 type or in combination of 2 or more types. In view of whiteness retention, it is preferable to use anionic surfactants and / or nonionic surfactants. In particular, in order to enhance the effect of the following (F) component, it is preferable to mainly use an anionic activator.

<Anion surfactant>

As an anionic surfactant which can be mix | blended with the medical detergent composition of this invention, the following are mentioned, for example.

(1) α-sulfo fatty acid alkyl ester salt (MES).

As the (alpha)-sulfo fatty acid alkyl ester salt, the kind in particular is not restrict | limited, Any of the (alpha)-sulfo fatty acid alkyl ester salt used for a general granular detergent composition can be used suitably. Suitable examples of the α-sulfo fatty acid alkyl ester salts are given below.

In said formula (A-1), R <^11> is a C8-C20, Preferably it is a C14-C16 linear or branched alkyl group, or a C8-C20 linear or branched alkenyl group. R <^12> is a linear or branched alkyl group, its carbon number is 1-6, It is preferable that it is 1-3. Specifically, a methyl group, an ethyl group, a propyl group, and an isopropyl group are mentioned, A methyl group, an ethyl group, and a propyl group are preferable, and a methyl group is especially preferable as washing power improved further.

M represents a counter ion, For example, Alkali metal salts, such as sodium and potassium; Amine salts such as monoethanolamine, diethanolamine and triethanolamine; Ammonium salt etc. are mentioned, Especially, an alkali metal salt is preferable.

(2) Straight or branched chain alkylbenzenesulfonate having an alkyl group having 8 to 18 carbon atoms (LAS).

(3) Alkyl sulfate or alkenyl sulfate having 10 to 20 carbon atoms.

(4) α-olefin sulfonates (AOS) having 10 to 20 carbon atoms.

(5) Alkanesulfonates having 10 to 20 carbon atoms.

(6) Alkyl ether sulfate (AES) having a linear or branched alkyl group or alkenyl group having 10 to 20 carbon atoms and added with ethylene oxide, propylene oxide, butylene oxide or a mixture thereof having an average added mole number of 10 mol or less; Alkenyl ether sulfate.

(7) Alkyl ether carbonates or eggs having a straight or branched chain alkyl group or alkenyl group having 10 to 20 carbon atoms and added with ethylene oxide, propylene oxide, butylene oxide or mixtures thereof with an average added mole number of 10 mol or less. Kenyl ether carbonate.

(8) Alkyl polyhydric alcohol ether sulfates, such as C10-C20 alkyl glyceryl ether sulfonic acid.

(9) C10-20 higher fatty acid salt.

Among the above examples, preferred anionic surfactants include an alkali metal salt of α-sulfofatty acid alkyl ester salt (MES), a linear alkylbenzene sulfonic acid (LAS) (for example, sodium or potassium salt), AOS, and AES alkali. Metal salts (e.g., sodium or potassium salts) and alkali metal salts of higher fatty acids (e.g., sodium or potassium salts). Among them, MES having an alkyl group having 14 to 16 carbon atoms, LAS having an alkyl group having 10 to 14 carbon atoms, and a higher fatty acid salt having 10 to 20 carbon atoms are particularly preferable.

These anionic surfactants can be used individually by 1 type or in combination of 2 or more types.

<Nonionic surfactant>

As a nonionic surfactant which can be mix | blended with the medical detergent composition of this invention, the following are mentioned, for example.

(1) polyoxyalkylene alkyl ether or poly with an average of 3 to 30 moles, preferably 3 to 20 moles of an alkylene oxide having 2 to 4 carbon atoms to an aliphatic alcohol having 6 to 22 carbon atoms, preferably 8 to 18 carbon atoms. Oxyalkylene alkenyl ether.

Among these, polyoxyethylene alkyl ether, polyoxyethylene alkenyl ether, polyoxyethylene polyoxypropylene alkyl ether, and polyoxyethylene polyoxypropylene alkenyl ether are suitable. As an aliphatic alcohol used here, a primary alcohol and a secondary alcohol are mentioned, A primary alcohol is preferable. In addition, an alkyl group or an alkenyl group may be linear, or a branched chain may be sufficient as it.

(2) polyoxyethylene alkyl phenyl ether or polyoxyethylene alkenylphenyl ether.

(3) Fatty acid alkyl ester alkoxylate which alkylene oxide added between ester bond of long-chain fatty acid alkyl ester, for example, shown by following General formula (I).

R ¹ CO (OA) N'OR ² (I)

[Wherein, R ¹ CO represents a fatty acid residue having 6 to 22 carbon atoms, preferably 8 to 18 carbon atoms; OA represents an addition unit (oxyalkylene group) of alkylene oxide having 2 to 4 carbon atoms, preferably 2 to 3 carbon atoms (for example, ethylene oxide, propylene oxide, etc.); N 'represents the average added mole number of alkylene oxide, and is generally a number of 3 to 30, preferably 5 to 20. R <^2> represents the lower (C1-C4) alkyl group which may have a C1-C3 substituent.]

(4) Polyoxyethylene sorbitan fatty acid ester.

(5) Polyoxyethylene sorbitan fatty acid ester.

(6) Polyoxyethylene fatty acid ester.

(7) Polyoxyethylene hardened castor oil.

(8) glycerin fatty acid ester.

Of the above nonionic surfactants, nonionic surfactants of (1) are preferred, and among them, polyoxyalkylene having an average of 5 to 20 moles of an alkylene oxide having 2 to 4 carbon atoms added to an aliphatic alcohol having 12 to 16 carbon atoms Particularly preferred are alkyl ethers or polyoxyalkylenealkenyl ethers.

Moreover, melting | fusing point is 50 degrees C or less, HLB is 9-16 polyoxyethylene alkyl ether, polyoxyethylene alkenyl ether, polyoxyethylene polyoxypropylene alkyl ether, polyoxyethylene polyoxypropylene alkenyl ether, fatty acid methyl ester. Fatty acid methyl ester ethoxylate to which ethylene oxide is added, and fatty acid methyl ester ethoxy propoxylate to which ethylene oxide and propylene oxide are added to fatty acid methyl ester are suitably used.

These nonionic surfactants can be used individually by 1 type or in combination of 2 or more types.

In addition, the above-mentioned "HLB" is a value calculated | required by the GRIFFIN method (refer to Yoshida, Shin-Doo, Ogaki, the co-production of the mountain, "The New Surfactant Handbook", KKK, 1991, page 234). ).

In addition, said "melting point" means the value measured by the melting-point measuring method described in JISK 0064-1992 "Method of melting | fusing point and melting range of a chemical product."

<Cation surfactant>

As a cation surfactant which can be mix | blended with the medical detergent composition of this invention, the following are mentioned, for example.

(1) Di long-chain alkyldi short-chain alkyl type quaternary ammonium salt.

(2) Mono long-chain alkyl tri short-chain alkyl type quaternary ammonium salt.

(3) Tri-chain alkyl mono short-chain alkyl type quaternary ammonium salt.

However, said "long chain alkyl" represents an alkyl group having 12 to 26 carbon atoms, preferably 14 to 18 carbon atoms.

"Short-chain alkyl" may contain substituents, such as a phenyl group, benzyl group, a hydroxy group, and a hydroxyalkyl group, and may have an ether bond between carbons. Among them, an alkyl group having 1 to 4 carbon atoms, preferably 1 to 2 carbon atoms; Benzyl group; Hydroxyalkyl groups having 2 to 4 carbon atoms, preferably 2 to 3 carbon atoms; C2-C4, Preferably 2-3 polyoxyalkylene group is mentioned as a suitable thing.

These cationic surfactants can be used individually by 1 type or in combination of 2 or more types.

<Positive surfactant>

As an amphoteric surfactant which can be mix | blended with the medical detergent composition of this invention, an imidazoline type amphoteric surfactant, an amide betaine type amphoteric surfactant, etc. are mentioned, for example. Specifically, 2-alkyl-N-carboxymethyl-N-hydroxyethyl imidazolinium betaine and lauric acid amide propyl betaine are mentioned as a suitable thing.

These amphoteric surfactants can be used individually by 1 type or in combination of 2 or more types.

In the medical detergent composition of this invention, the total compounding quantity of surfactant is 5 mass% or more and 40 mass% or less mainly with respect to the gross mass of the composition, Preferably it is 10% or more, 40 mass% or less, More preferably, It is 10 mass% or more and 30 mass% or less. By setting it as said range, sufficient washing | cleaning power and whiteness retention can be acquired.

[(F) component]

The component (F) used in the medical detergent composition of the present invention is one or two or more components selected from anionic water-soluble and / or semi-dispersible fluorescent brighteners and water-insoluble blue pigments. By mix | blending the said (F) component, the whiteness of the white matter which falls by washing repeatedly can be restored, or the fall of the whiteness of the white matter by repeated washing can be prevented.

In the medical detergent composition of the present invention, as an anionic water-soluble fluorescent brightener that can be blended as (F) component, for example, 4,4'-bis- (2-sulphostyryl) -biphenyl salt, 4 , 4'-bis- (4-chloro-3-sulphostyryl) -biphenyl salt, 2- (styrylphenyl) naphthothiazole derivative, and the like.

In the medical detergent composition of the present invention, as an anionic semi-dispersive fluorescent brightener that can be blended as (F) component, for example, 4,4'-bis (triazol-2-yl) stilbene derivative, bis- (Triazinylamino stilbene) disulfonic acid derivative etc. are mentioned.

The said fluorescent brightener can be used individually by 1 type or in combination of 2 or more types.

A commercial item can be used for the said fluorescent brightener. For example, Whiteex SA and Whiteex SKC (above, brand names; Sumitomo Chemical Co., Ltd. product); Chinopal MS-GX, Chinopal BS-X, Chinopal BS-X (above, brand names; BASF Corporation make); Lemonite CBUS-3B (above, a brand name; the product made by Khyati Chemicals) etc. is mentioned as a suitable thing. Especially, chinopal BS-X and chinopal MS-GX are more preferable.

In the medical detergent composition of the present invention, as the water-insoluble blue pigment which can be blended as the component (F), the pigment is preferable in terms of storage stability, and particularly preferably has oxidation resistance.

As these pigment | dyes, an oxide etc. are mentioned, for example, Preferably, iron oxide, copper phthalocyanine, cobalt phthalocyanine, ultramarine blue, blue blue, cyanine blue, cyanine green, etc. are mentioned.

The compounding quantity of the fluorescent brightener which is (F) component is mainly 0.001-1 mass% with respect to the gross mass of a medical detergent composition, Preferably it is 0.01-0.50 mass%, More preferably, it is 0.05-0.50 mass%. When the compounding quantity of the fluorescent brightener is 0.001% by mass or more, good whiteness of clothing can be achieved. When the amount of the fluorescent brightener exceeds 1% by mass, the effect on whiteness may be saturated or a quenching phenomenon may occur.

The compounding quantity of the water-insoluble blue pigment | dye which is (F) component is 0.001-0.5 mass% mainly with respect to the gross mass of a medical detergent composition, Preferably it is 0.005-0.2 mass%, More preferably, it is 0.01-0.1 mass%. If the blending amount of the water-insoluble blue pigment is 0.001% by mass or more, good whiteness of the garment can be achieved, and if it exceeds 0.5% by mass, the effect on whiteness may be saturated.

[(G) component]

(G) component used by the medical detergent composition of this invention is a cellulase. Cellulase acts on clothing, preventing the adhesion of particle dirt. Furthermore, the effect of the said (F) component, especially anionic semi-disperse fluorescent brightener, is improved.

In the medical detergent composition of this invention, as a cellulase which can be mix | blended as (G) component, For example, Celzyme, keazime, Celclean (Novozyme injection) of a commercial item; Puradax HA1200E (made by Genenko Asa); KAC500 (made by Gao Corporation); Alkali Cellulase K, Alkali Cellulase K-344, Alkali Cellulase K-534, Alkali Cellulase K-539, Alkali Cellulase K-577, Alkali Cellulase K-425, Alkali Cellulase K-521, Alkali Cellulase K-580, Alkali Cellulase K-588, Alkali Cellulase K-597, Alkali Cellulase K-522, CMCase I, CMCase II, Alkali Cellase E-II, and Alkali Cellulase E-III (above, Cellulase as described in Unexamined-Japanese-Patent No. 63-264699) etc. are mentioned.

The said cellulase can be used individually by 1 type or in combination of 2 or more types.

In addition, it is suitable to use cellulase granulated as separately stable particles in a dry blended state with a detergent dough (particle), and as a method for assembling enzyme-containing particles, Japanese Patent Application Laid-Open No. 53-6484, Japan Japanese Patent Application Laid-Open No. 60-262900, Japanese Patent Application Laid-Open No. 62-257990, Japanese Patent Application Laid-Open No. 1-12983, Japanese Patent Application Laid-Open No. 3-503775, Japanese Patent Application Laid-Open No. 4-503369, Japanese Patent Application Laid-Open No. 2000-178593 And the method described in the publication. As for the average particle diameter of the said enzyme containing particle | grain, 200-1000 micrometers is preferable from a point of solubility and storage stability, More preferably, it is 300-700 micrometers.

As for the compounding quantity of (G) component, 0.01-2 mass% is preferable with respect to the gross mass of the medical detergent composition from a viewpoint of the effect improvement performance of the said (F) component, More preferably, it is 0.1-2 mass%. If it is 0.01 mass% or more, a favorable effect can be acquired, and when it exceeds 2 mass%, recontamination prevention ability may be saturated.

[Optional ingredients]

The medical detergent composition of this invention may contain the other component which can be mix | blended with a normal medical detergent composition other than the said component (A)-(G) in the range which does not impair the effect of this invention. Although it does not specifically limit as the other component, For example, what is shown below is mentioned.

Cleanliness builder

In the medical detergent composition of the present invention, other detergent builders can be used in addition to the component (B), the component (C) and the component (D). The detergent builders are roughly classified into inorganic builders and organic builders.

As an inorganic builder, in addition to (B) component, (C) component, and (D) component, For example, Crystalline layered sodium silicate (For example, the brand name [Na-SKS-6] (δ-) by the Kurarithanto company, Inc.). Crystalline alkali metal silicates and amorphous alkali metal silicates such as Na2O.2SiO2)); Sulfates such as sodium sulfate and potassium sulfate; Alkali metal chlorides such as sodium chloride and potassium chloride; Phosphates such as oxophosphate, pyrophosphate, tripolyphosphate, metaphosphate, hexametaphosphate and phytin salts; And a complex of sodium carbonate and an amorphous alkali metal silicate (for example, Rhodia trade name "NABION15").

Among the inorganic builders, crystalline alkali metal silicates and alkali metal chlorides are preferable.

When mix | blending a crystalline alkali metal silicate, content in the medical detergent composition becomes like this. Preferably it is 0.5-40 mass%, More preferably, it is 1-25 mass%, More preferably, it is 3-20 It is mass%, Especially preferably, it is 5-15 mass%.

When mix | blending an alkali metal chloride, content in the medical detergent composition becomes like this. Preferably it is 1-10 mass%, More preferably, it is 2-8 mass%, More preferably, 3-7 in terms of the effect of solubility improvement. Mass%.

As an organic builder, For example, amino carbonates, such as a nitrilo triacetate, ethylenediamine tetraacetic acid salt, (beta) -alanine diacetate, aspartic acid diacetate, methylglycine diacetate, and imino diacetate; Hydroxyamino carboxylic acid salts such as serine diacetate, hydroxyimino diacetate, hydroxyethyl ethylenediamine triacetate and dihydroxyethylglycine salt; Hydroxy carbonates such as hydroxyacetate, tartarate, citrate and gluconate; Cyclocarboxylic acid salts such as pyromellitate salts, benzopolycarbonate salts and cyclopentane tetracarboxylic acid salts; Ether carbonates such as carboxymethyl tartrate, carboxymethyloxysuccinate, oxydisuccinate, tartaric acid mono or disuccinate; Salts of polyacetalcarboxylic acids such as polyacrylates, salts of acrylic acid-allyl alcohol copolymers, salts of acrylic acid-maleic acid copolymers, and polyglyoxylic acids; Salts of acrylic acid polymers or copolymers such as hydroxyacrylic acid polymers and polysaccharide-acrylic acid copolymers; Salts of polymers or copolymers such as maleic acid, itaconic acid, fumaric acid, tetramethylene 1,2-dicarboxylic acid, succinic acid and aspartic acid; And polysaccharide derivatives such as polysaccharide oxides such as starch, cellulose, amylose and pectin.

Among the organic builders, citrate, aminocarboxylic acid salts, hydroxyaminocarboxylic acid salts, polyacrylates, salts of acrylic acid-maleic acid copolymers, and salts of polyacetalcarboxylic acid are preferable. In particular, the hydroxy imino diacetate, the salt of the acrylic acid-maleic acid copolymer having a weight average molecular weight of 1000 to 80000, the polyacrylate, the polyglyoxylic acid having a weight average molecular weight of 800 to 1000000 (preferably 5000 to 200000) and the like Polyacetal carbonates (for example, those described in Japanese Patent Application Laid-Open No. 54-52196) are suitable.

The said builders can be used individually by 1 type or in combination of 2 or more types as appropriate.

<Bleach activator, bleach activator catalyst>

In the medical detergent composition of the present invention, a bleach activator or a bleach activating catalyst can be used.

As a bleach activator, a well-known compound can be used, Preferably an organic peracid precursor is used.

Examples of the organic peracid precursor include tetraacetylethylenediamine, alkanoloxybenzenesulfonic acids having 8 to 12 carbon atoms, alkanoloxybenzoic acids having 8 to 12 carbon atoms, and salts thereof. Among these, 4-decanoyloxybenzoic acid and 4- Sodium dodecanoyloxybenzene sulfonate and sodium 4-nonanoyloxybenzene sulfonate are preferable. These can be used 1 type or in combination of 2 or more types as appropriate.

The particle | grains containing a bleach activator can be manufactured by a well-known manufacturing method. For example, it can manufacture by the extrusion granulation method and the granulation method by the tablet shape using a briquette machine.

Specifically, the organic peracid precursor particles are organic peracid precursors and olefin sulfonates in the heat melted solid binder materials at room temperature such as polyethylene glycols of PEG # 3000 to # 20000, preferably PEG # 4000 to # 6000, Powders of surfactants such as alkylbenzene sulfonates and alkyl sulfate ester salts are pulverized, extruded to prepare noodle-shaped organic peracid precursor granules having a diameter of about 1 mm, and then lightly pulverized to a length of 0.5 to 3 mm to blend. It is preferable to be. As a powder of surfactant, the alpha-olefin sulfonate of alkyl chain length 14 is preferable.

As a bleaching activation catalyst, a well-known compound can be used. As a specific example, transition metal atoms and ligands, such as copper, zinc, iron, manganese, nickel, cobalt, chromium, vanadium, ruthenium, rhodium, palladium, rhenium, tungsten, molybdenum, form a complex through a nitrogen atom, an oxygen atom, etc. As one thing, as a transition metal contained, copper, zinc, cobalt, manganese, etc. are preferable, and copper, zinc, manganese is especially preferable. In particular, the bleaching activation catalyst described in JP-A-2004-189893 and JP-A-2011-57745 is preferable.

Particles containing a bleach activating catalyst can be produced by a known granulation method. For example, it can manufacture by the granulation method by the extrusion granulation method and the tablet shape using a briquette machine.

<Enzyme>

In the medical detergent composition of the present invention, other enzymes can be used in addition to the component (G).

For example, hydrolases, oxidoreductases, lyases, transferases, and isomerases can be cited when classified from the reactivity of enzymes, and any of them can be applied in the present invention. Among them, proteases, esterases, lipases, nucleases, amylases, pectinases and the like are preferred.

Specific examples of the protease include pepsin, trypsin, chymotrypsin, collagenase, keratinase, elastase, subtilisin, papain, promerin, carboxypeptidase A or B, aminopeptidase, and aspergillo. Peptidase A, B, etc. are mentioned. Examples of commercially available products of proteases include savinase, alkalase, cannase, ebarase, and deozyme (above, trade name; novozyme injection); API21 (brand name, fire extinguishing company make); Makusakal, Makusa fem, Furapekuto, Furoperase, Furapasto (above, brand names; manufactured by Danisco Co.); Protease K-14 or K-16 (protease of Unexamined-Japanese-Patent No. 5-25492) etc. are mentioned.

Specific examples of esterases include gastric lipases, pancreatic lipases, plant lipases, phospholipases, choline esterases, and phosphatases.

As a specific example of a lipase, commercial lipases, such as a lipolase, a Lipex (above, brand name; Novozyme injection product), and a liposam (brand name, the digestion major company make), etc. are mentioned.

Examples of the amylase include commercially available stainzyme, tamil, duramil (made by Novozyme injection), furasta, pawarase (above, trade name; manufactured by Danisco Co., Ltd.), and the like.

The said enzyme can be used individually by 1 type or in combination of 2 or more types.

In addition, it is preferable to use what the enzyme granulated as separately stable particle | grains in the dry blended state with the detergent dough (particle).

In the medical detergent composition of the present invention, the content of the enzyme, which is an optional component, is preferably 0.2 to 2% by mass.

Enzyme Stabilizer

In the medical detergent composition of the present invention, enzyme stabilizers can be used.

As an enzyme stabilizer, calcium salt, magnesium salt, a polyol, formic acid, a boron compound, etc. can be mix | blended, for example. Among them, sodium tetraborate, calcium chloride and the like are preferable.

An enzyme stabilizer can be used individually by 1 type or in combination of 2 or more types.

As for content of the enzyme stabilizer in the medical detergent composition of this invention, 0.05-2 mass% is preferable.

<Polymers>

In the medical detergent composition of the present invention, polyethylene having an average molecular weight of 200 to 200000 as a binder or a powder physical modifier used for densifying the detergent composition particles or to impart a recontamination prevention effect on hydrophobic fine particles (dirt). Glycols, salts of acrylic acid and / or maleic acid polymers having a weight average molecular weight of 1000 to 100000, polyvinyl alcohol, hydroxypropyl methyl cellulose (HPMC), weight average molecular weight of 100,000 to 1.2 million carboxymethyl cellulose (CMC), cationized cellulose, and the like. Cellulose derivatives, cellulose such as powdered cellulose, and the like can be blended.

Moreover, as a dirt release agent, the copolymer of the repeating unit derived from terephthalic acid, and the repeating unit derived from ethylene glycol and / or propylene glycol, a terpolymer, etc. can be mix | blended.

Moreover, polyvinylpyrrolidone etc. can be mix | blended in order to provide the color change prevention effect.

These polymers can be used individually by 1 type or in combination of 2 or more types.

As for content of the said polymer in the medical detergent composition of this invention, 0.05-5 mass% is preferable.

<Caking inhibitor>

As an anti-caking agent, paratoluene sulfonate, xylene sulfonate, an acetate, a sulfo pumpkin salt, talc, fine powder silica, clay, magnesium oxide, etc. are mentioned, for example.

As an anti-caking agent, it can be used individually by 1 type or in combination of 2 or more types.

<Defoamer>

Examples of the antifoaming agent include conventionally known silicone- / silica-based ones.

The antifoaming agent may be an antifoaming agent granulated product produced using the method described in the lower left column of Japanese Patent Application Laid-Open No. 3-186307. Specifically, 20 g of Dow Corning's silicone (compound type, PS antifoam) is added to 100 g of maltodextrin (enzyme-modified dextrin) manufactured by Nippon Chemical Co., Ltd. as a defoaming component, and mixed to obtain a homogeneous mixture. Next, after mixing 50 mass% of the obtained homogeneous mixture, 25 mass% of polyethyleneglycol (PEG-6000, melting | fusing point 58 degreeC), and 25 mass% of neutral anhydrous manganeses at 70-80 degreeC, the extrusion granulator (model EXKS made by Fuji Powder Co., Ltd.) It assembles by -1) and a granulated material is obtained.

As an antifoamer, 1 type can be used individually or in combination of 2 or more types as appropriate.

Metal ion trapping agent

The metal ion trapping agent has an effect of trapping trace metal ions and the like in tap water, and suppressing the adsorption of metal ions to the fiber (the object to be cleaned).

As a metal ion trapping agent which can be mix | blended with the medical detergent composition of this invention, In addition to what is contained in the said cleaning builder, Amino polyacetic acids, such as glycol ethylenediamine hexaacetic acid; 1-hydroxyethane-1,1-diphosphonic acid (HEDP-H), ethane-1,1-diphosphonic acid, ethane-1,1,2-triphosphonic acid, hydroxyethane-1,1,2 Triphosphonic acid, ethane-1,2-dicarboxy-1,2-diphosphonic acid, hydroxymethanephosphonic acid, ethylenediaminetetra (methylenephosphonic acid), nitrilotri (methylenephosphonic acid), 2-hydroxyethyl Organic phosphonic acid derivatives or salts thereof such as iminodi (methylenephosphonic acid), hexamethylenediaminetetra (methylenephosphonic acid) and diethylenetriaminepenta (methylenephosphonic acid); Organic acids, such as diglycolic acid, tartaric acid, oxalic acid, and gluconic acid, or its salt, etc. are mentioned.

The said metal ion trapping agent can be used individually by 1 type or in combination of 2 or more types.

As for content of the metal ion trapping agent in the medical detergent composition of this invention, 0.1-5 mass% is preferable, More preferably, it is 0.5-3 mass%. If it is 0.1 mass% or more, the effect which captured the metal ion in tap water will improve. On the other hand, when it is 5 mass% or less, the effect which captured a metal ion is fully acquired.

<pH regulator>

Although the pH in particular does not restrict | limit the medical detergent composition of this invention, It is preferable that pH in 1 mass% aqueous solution of the medical detergent composition is 8 or more from the point of washing performance, and pH in this 1 mass% aqueous solution is It is more preferable that it is 9-11. When the said pH is 8 or more, a washing | cleaning effect becomes easy to be exhibited.

As a technique for controlling the pH of a medical detergent composition, pH adjustment is normally performed by the alkali agent, The alkali agent etc. which were described to the said cleaning builder are mentioned.

Specifically, in terms of solubility in water and alkalinity, NABION15 (brand name) described also as the cleaning builder, wherein the ratio of sodium carbonate to sodium silicate and water is a mixture of 55/29/16 (mass ratio). Rhodia Co., Ltd.) is preferably used.

In addition, in order to prevent the pH of a medical detergent composition from becoming too high, you may adjust to the said pH range using an acid etc.

As such an acid, an alkali metal phosphate dihydrogen salt such as a metal ion trapping agent, potassium dihydrogen phosphate, lactic acid, succinic acid, malic acid, gluconic acid, or polycarboxylic acid thereof can be used.

It is also possible to use a buffer for preventing the drop in pH due to the acid component derived from the soil of the fiber during washing.

The said pH adjuster can be used individually by 1 type or in combination of 2 or more types.

<Fragrance>

The fragrance which can be used in the medical detergent composition of the present invention is not particularly limited, and any one generally used in detergents may be used, and it is composed of a perfume component, a solvent, a perfume stabilizer, and the like.

As these perfumes, the thing of Unexamined-Japanese-Patent No. 2002-146399, Unexamined-Japanese-Patent No. 2003-89800, etc. can be used, for example.

0.001-2 mass% is preferable, and, as for content of the fragrance | flavor in a medical detergent composition, 0.01-1 mass% is more preferable.

The medical detergent composition of this invention is a solid detergent composition, for example, is a tablet composition and granular detergent composition. Preferably, the medical detergent composition of the present invention is a granular detergent composition.

Although the manufacturing method of the medical detergent composition of this invention is not specifically limited, For example, when it is a granular detergent, the 1st process of obtaining surfactant containing particle | grains, the obtained surfactant containing particle | grains, and functional particle (for example, Sodium percarbonate particles and the like) can be produced by the second step of mixing while flowing.

A 1st process is a process of obtaining surfactant containing particle | grains, A conventionally well-known method can be used. For example, first, a spray drying slurry is prepared by dispersing and dissolving a surfactant, an alkali metal carbonate or an optional component in water (slurry preparation operation), and drying the spray drying slurry with a spray dryer to spray spray dried particles. (Spray operation). In addition, the spray-dried particles obtained by the spraying operation can be granulated (assembling operation) together with a surfactant or an optional component to obtain surfactant-containing particles. If necessary, the obtained surfactant-containing particles may be divided into sieves and adjusted to a desired average particle diameter and particle size distribution (quadrant operation).

In the spray operation, during spray drying of the spray drying slurry, a hot gas is supplied into the spray drying tower. This hot gas is supplied from the lower part of a spray drying tower, for example, and is discharged | emitted from the tower top of a spray drying tower. As temperature of this hot gas, 170-300 degreeC is preferable and 200-290 degreeC is more preferable. If it is in the range, spray-drying slurry can fully be dried and spray-drying particle | grains of desired moisture content can be obtained easily. Moreover, as for the temperature of the gas discharged | emitted from the spray drying tower, 70-125 degreeC is preferable normally, and 70-115 degreeC is more preferable.

In addition, when hot gas is supplied from the lower part of the spray drying tower and discharged from the top of the spray drying tower (counterflow type), in order to suppress that the temperature of the spray drying particle obtained becomes too high, it is cold wind from the lower part of the spray drying tower. Can be supplied. At the same time, for example, inorganic fine particles (zeolite, etc.) are introduced from the lower part of the spray drying tower and brought into contact with the spray dried particles to prevent the spray dried particles from adhering to the inner wall of the spray drying tower, The fluidity | liquidity improvement of the spray dried particle obtained can be aimed at. As the spray drying tower, either a countercurrent type or a cocurrent type type may be used. Among them, the countercurrent type is preferable because the thermal efficiency and the spray dried particles can be sufficiently dried. As atomization apparatus of the spray drying slurry, a pressure spray nozzle, a two-fluid spray nozzle, a rotary disk type, etc. are mentioned. Especially, it is preferable to use the pressure spray nozzle which is easy to obtain a desired average particle diameter. Here, a "pressure spray nozzle" includes the whole nozzle used when atomizing by spraying the spray drying slurry while extruding from the spray port of the nozzle by applying pressure. Especially, the nozzle which has a structure which guides a spray drying slurry from one or several inlets of the nozzle to the vortex chamber in the nozzle, and injects it from a spray port as a swirl flow in the vortex chamber, especially desirable. As pressure at the time of spraying, 2-4 MPa (gauge pressure) is preferable, More preferably, it is 2.5-3 MPa (gauge pressure).

The granulation operation can use a conventionally well-known method, For example, grinding granulation which grinds and grinds a spray dry particle and other arbitrary components, stirring granulation, rolling granulation, fluidized bed granulation, etc. are mentioned. In a granulation operation, it can granulate, spraying water, a nonionic surfactant, or the water dispersion of a nonionic surfactant with arbitrary droplet diameters to spray drying particle | grains and other arbitrary components.

The temperature of the melt of the nonionic surfactant sprayed in the granulation operation or the aqueous dispersion of the nonionic surfactant is not particularly limited, but is preferably 70 to 85 ° C.

Although the droplet diameter is not specifically limited, 100-200 micrometers is preferable. The droplet diameter can be measured by a laser particle size measuring device, for example. As this laser particle size measuring apparatus, LDSA-1400A etc. made from the same computer application, etc. are mentioned, for example.

In the granulation operation, the temperature of the spray dried particles and other optional components is not particularly limited, but is preferably 20 to 40 ° C.

The quadrant operation is, for example, preparing sieves of plural kinds of net sizes, laminating in order from the sieves having the smallest net size to the sieves having the largest sieve size to form a sieve unit, and containing surfactant-containing particles on top of the sieve unit. Input, vibrate the sieve unit and divide into sieves. The surfactant-containing particles remaining on the sieve are collected for each sieve, and the recovered surfactant-containing particles can be mixed to obtain surfactant-containing particles having a desired average particle size or particle size distribution.

The 2nd process is a process of mixing surfactant containing particle | grains, functional particle, etc., and a conventionally well-known method can be used. For example, the method of mixing these particles, making it flow with a stirring granulator, a rolling granulator, and a fluidized bed granulator, is mentioned.

As a mixing operation, the method of adding and mixing the particle | grains using the container rotary cylindrical mixer provided with the stirring blade in the bottomed cylindrical container, for example is mentioned. As a container rotary cylindrical mixer, the container rotary cylindrical mixer of Unexamined-Japanese-Patent No. 2005-154648 is mentioned, for example.

In the mixing operation using a container rotary cylindrical mixer, it is preferable to set the number of Frudes (Fr) represented by the following formula (2) to 0.01 to 0.8. By making Fr into the said range, the particle | grains can be mixed favorably.

Fr = V ² / (R × g)... (2)

[Wherein, in the formula (2), V represents the circumferential speed (m / s) of the outermost circumference of the stirring blade of the container rotary cylindrical mixer. R represents the radius m from the center of rotation of the outermost circumference in the container rotary cylindrical mixer. g denotes the acceleration of gravity (m / s ² ).]

Although the medical detergent composition of this invention is not specifically limited, For example, it can be used as follows.

When washing textile products, such as a medical product, the medical detergent composition of this invention can be put into a washing machine according to the amount of laundry, for example, can be used, melt | dissolved in the water etc. which contained in the container. The washing may be performed in a short time or may be soaked.

[Example]

EMBODIMENT OF THE INVENTION Hereinafter, although this invention is demonstrated in detail, referring an Example, the scope of the present invention is not limited at all by these examples.

&Lt; Component (A) >

(A) component used by the Example and the comparative example is shown below.

(A) -1: sodium percarbonate (manufactured by Zhejiang Jinke Chemicals, trade name; SPCC, 43.5 mass% of carbonate root, average particle diameter: 870 µm).

(A) -2: Sodium percarbonate (made by Nippon Peroxide, brand name: PC-W, 48.8 mass% of carbonate roots, average particle diameter 850 micrometers).

<Component (B)>

(B) component used by the Example and the comparative example is shown below.

(B) -1: Sodium hydrogen carbonate (made by Penrice, brand name; SODIUM BICARBONATE FOOD GRADE COARSE GRANULAR, 72.6 mass% of hydrogen carbonate roots, an average particle diameter of 300 micrometers, content of particle | grains less than 150 micrometers; 3 mass%, particle diameter 600 micrometers) The above particles are not included).

(B) -2: Sodium hydrogen carbonate (made by Asahi Glass Co., Ltd., brand name: sodium bicarbonate (for general industry), aerial KG, 72.6 mass% of hydrogen carbonate roots, 250 micrometers of average particle diameters, content of particle | grains less than 150 micrometers) 15 mass% and a particle diameter of 600 micrometers or more are not included).

(B) -3: Potassium hydrogen carbonate (manufactured by Kanto Chemical Co., Ltd., a reagent, 61.0 mass% of hydrogen carbonate).

&Lt; Component (C) >

(C) component used by the Example and the comparative example is shown below.

(C) -1: sodium carbonate (manufactured by Asahi Glass Co., Ltd., heavy sodium carbonate, trade name; soda ash, 56.6% by mass of carbonate, average particle diameter of 320 µm, bulk density of 1.07 g / cm 3)

(C) -2: Potassium carbonate (made by Asahi Glass Co., Ltd., brand name: potassium carbonate (powder), 43.5 mass% of carbonate roots, an average particle diameter of 490 micrometers, volume density 1.30 g / cm <3>).

<Component (D)>

(D) component used by the Example and the comparative example is shown below.

(D) -1: A zeolite (Mizusawa Chemical company make, brand name: Silton B, 80 mass% of pure components).

<Component (E)>

(E) component used by the Example and the comparative example is shown below.

(E) -1: MES, C16: C18: C18 = 80: 20 (mass ratio) of sodium salt of fatty acid methyl ester sulfonate (made by Lion Corporation, AI = 70%, remainder unreacted fatty acid methyl ester, sodium sulfate, Methylsulfate, hydrogen peroxide, water, etc.).

(E) -2: 48 mass of LAS-Na and linear alkyl (C10-C14) benzenesulfonate (Lipon LH-200 (96 mass% of LAS-H pure components, Lion Corporation make) at the time of preparation of surfactant composition) Neutralize with% aqueous sodium hydroxide solution). The compounding quantity in the following table | surface shows the mass% as LAS-Na.

(E) -3: Soap, C12-C18 fatty acid sodium (made by Lion Co., Ltd., pure; 67 mass%, titer; 40-45 degreeC, fatty acid composition; C12 = 11.7 mass%, C14 = 0.4 mass%, C16 = 29.2 mass%, C18F0 (stearic acid) = 0.7 mass%, C18F1 (oleic acid) = 56.8 mass%, C18F2 (linoleic acid) = 1.2 mass%, molecular weight: 289).

(E) -4: nonionic surfactant, LMAO-90 (brand name, Nippon Catalyst) [polyoxyethylene (EO15 ^* ) alkyl (C12-14 ^** ) ether]. ^* (EO15) shows that the average added mole number of ethylene oxide is 15. ^** (C12-14) shows an alkyl group having 12 to 14 carbon atoms.

<Component (F)>

(F) component used by the Example and the comparative example is shown below.

(F) -1: chinopal BS-X (brand name, the product made by BASF, a distyryl biphenyl derivative, a water-soluble fluorescent agent).

(F) -2: chinopal MS-GX (brand name, the BASF Corporation make, a bis (triazinyl amino stilbene) disulfonic acid derivative, a semi-dispersive fluorescent substance).

(F) -3: Naked office (brand name, the Dai-Nichi Chemical Co., Ltd. make, Ultramarine Blue, water-insoluble blue pigment).

<Component (G)>

(G) component used by the Example and the comparative example is shown below.

(G) -1: CellClean 4500T (trade name, Novozyme injection).

(G) -2: Keazime 4500T (trade name, manufactured by Novozyme Injection).

(G) -3: Puradax HA1200E (brand name, the product made by Genenco Co., Ltd.).

<Other ingredients>

Other components other than (A)-(G) component used by the Example and the comparative example are shown below.

MA agent: Acrylic acid-maleic anhydride copolymer sodium salt (brand name: Aquaric TL-400, 40 mass% of pure components aqueous solution, the Nippon-Catalyst company make).

Sulfuric acid Na: neutral anhydrous forage A0, manufactured by Shikoku Kasei Kogyo Co., Ltd.

Sulfurous acid Na: Sulfuric anhydride procurement (manufactured by Shinju Chemical Co., Ltd.).

Bleach activator (OBS granulated product): Synthesis of 4-dodecanoyloxybenzene sulfonate sodium as a bleaching activator, 4-hydroxybenzene sulfonate sodium (Kanto Chemical Co., Ltd. reagent), N, N-dimethyl as a raw material Formamide (Kanto Chemical Co., Ltd. reagent), lauric acid chloride (Tokyo Chemical Industry Co., Ltd. reagent), and acetone (Kanto Chemical Co., Ltd. reagent) were used and the following method was performed. 3000 g (15.3 mol) of sodium 4-hydroxybenzenesulfonate previously dehydrated was dispersed in 9000 g of N, N-dimethylformamide, and 3347 g (15.3 mol) of lauric chloride was stirred at 50 ° C for 30 minutes while stirring with a steerer. It dripped. After completion of the dropwise addition, the reaction was carried out for 3 hours, and the N, N-dimethylformamide was distilled off at 100 ° C under reduced pressure (0.5 to 1 mmHg). After washing with acetone, it was recrystallized and purified in a water / acetone (= 1/1 mol) solvent to obtain crystals of sodium 4-dodecanoyloxybenzenesulfonate. The yield was 90%. 70 mass parts of sodium 4-dodecanoyloxybenzene sulfonate synthesize | combined by the above-mentioned method, 20 mass parts of PEG (brand name: polyethyleneglycol # 6000M (made by Lion Corporation)), and the alpha-olefin sulfonate powder product of 14 carbon atoms (brand name) : Liporan PJ-400 (manufactured by Lion Co., Ltd.) was added to Extrud Ohmic EM-6 type (trade name) manufactured by Hosokawa Micron Co., Ltd. so as to have a total of 5000 g, and the diameter was 0.8 by kneading extrusion. A noodle-shaped extruded article was obtained. This extruded product (60 ° C.) was introduced into a Fitzmill DKA-3 (trade name) manufactured by Hosokawa Micron, Inc., and 5 parts by mass of the A-type zeolite powder was similarly supplied as a preparation and ground to a bleaching activator having an average particle diameter of about 700 μm. The granulated product was obtained. (The compounding quantity shown in the following table is an amount as a granulated material.)

CMC: Carboxymethyl cellulose (made by Daicel Chemical Industries Ltd., brand name; CMC diecel 1190). Enzyme 1: A mixture of Ebarase 8T / Lipex 50T = 8/2 (mass ratio), Novozyme injection.

Enzyme 2: A mixture of Furoperase 4000D / Mannastar 375 = 8/2 (mass ratio), manufactured by Genenco Corporation.

Fragrance: Fragrance composition A of Table 11-18 of Unexamined-Japanese-Patent No. 2002-146399.

<Preparation of medical detergent composition>

According to the composition table shown to the following Tables 1-4, the granular medical detergent composition was obtained by the following manufacturing methods.

Preparation Method A (Examples 1 to 10, 15, and 16)

Process (1)

Into the aqueous slurry (prepared at 25 mass% of water concentration) of MES obtained by sulfonating and neutralizing the fatty acid ester which is a raw material, a part of nonionic surfactant (25 mass% with respect to MES) is thrown in, and a water concentration is carried out. The mixture was concentrated under reduced pressure with a thin film dryer until 11 mass% was obtained, to obtain a mixed concentrate of MES and a nonionic surfactant. In addition, in the following manufacturing method, the component whose compounding quantity is not described in following Tables 1-4 shall not be added in the Example.

Process (2)

Water was put into the mixing vessel with a jacket provided with a stirring device, and the temperature was adjusted to 80 degreeC. Surfactant except MES and nonionic surfactant was added to this, and it stirred for 10 minutes. Subsequently, MA agent was added. After stirring for another 10 minutes, a part of (D) component (from the compounding quantity described in the following table, 1.0 mass% for the addition at the time of the kneading | feeding-in added in the following process (3), 5.0 mass% for grinding aids, and the following process (4)) Amount except the 1.0 mass% for surface modification to be added), (C) component and sodium sulfate were added. After further stirring for 20 minutes to prepare a spray drying slurry having a water content of 38% by mass (slurry preparation operation), using a countercurrent spray drying tower, spray drying was carried out under the condition of a hot air temperature of 280 ° C, and the average particle diameter (mass: 50%) 320 Spray dried particles having a 占 퐉, a bulk density of 0.30 g / cm 3 and a moisture of 5% were obtained (spray operation).

Process (3)

The obtained spray-dried particle | grains, the mixed concentrate obtained by the process (1), 1.0 mass% (D) component, a nonionic surfactant (0.3 mass% of nonionic surfactants for spray addition sprayed at the following process (4), and The remainder except the nonionic surfactant in the mixed concentrate), (F-1) component, (F-2) component, and water are added to a continuous kneader (KRC-S12 type, manufactured by Kurimoto Iron Works Co., Ltd.), It kneaded on the conditions of the rotation speed of kneader 135rpm, and jacket temperature of 60 degreeC, and obtained the 6% by mass of the water containing surface-active agent (chemical treatment). The raw material is cut with a cutter (5 m / s in cutter speed) while extruding the raw material into a ferret double (EXDFJS-100, manufactured by Fuji Powder Co., Ltd.) having a die having a hole diameter of 10 mm. Pellet-shaped moldings of about mm were obtained.

Subsequently, 5.0 mass% equivalent amount of (D) component (average particle diameter 180 micrometers) as a grinding | pulverization adjuvant was added to the obtained pellet-shaped molded object, and the pits mill arrange | positioned in three steps in series under cold air (10 degreeC, 15 m / s) coexistence ( Grinded using Hosokawa Micron Co., Ltd., DKA-3, and crushed product (screen hole diameter: 1st stage / 2nd stage / 3rd stage: 12mm / 6mm / 3mm, rotation speed: 1st stage / 2th stage / 3) At the same time, 4700 rpm) was obtained (assembly operation).

Process (4)

According to the composition of Tables 1 to 4 below, the pulverized product, the component (A), the component (B), the CMC and the OBS granulated material were simultaneously introduced into the vessel rotary cylindrical mixer at a rate of 15 kg / min and mixed. This container rotary cylindrical mixer is characterized in that the container has four flat blades each having a diameter of 0.7m, a length of 1.4m, an inclination angle of 3.0 °, an exit hill height of 0.15m, an inner mixing vane of 0.1m in height, and a length of 1.4m every 90 °. Will. In addition, the rotation speed of the internal mixing blade was adjusted so that Froud number might be Fr = 0.2.

1.0 mass% (D) component for surface modification was added to the particle | grain group rotated and fluidized by the container, and 0.3 mass% of nonionic surfactant aqueous dispersion and fragrance | flavor adjusted to 75 degreeC were sprayed 1 Motored for a minute.

In order to color a part of the obtained detergent composition precursor, the particles were transferred to a belt conveyor at a speed of 0.5 m / s (30 mm in height of the surfactant-containing particle layer on the belt conveyor and 300 mm in width), and the surface thereof (F- 3) 20% aqueous dispersion of the component was sprayed.

Using the said container rotary cylindrical mixer, the detergent composition precursor which colored a part, (G) component, and the enzyme were mixed for 5 minutes on the conditions similar to the above, and the detergent composition was obtained. (The obtained detergent composition was 400 micrometers in average particle diameter.)

Manufacturing Method B (Example 11)

5.0 mass% of sodium sulfate as a grinding aid in the above-mentioned process (3), 1.0 mass% of sodium sulfate as a surface modifier in the above-mentioned process (4), and (D) component whole quantity (1 mass) in a process (2) %) Except having added, it carried out similarly to the manufacturing method A, and obtained the granular detergent composition.

Manufacturing Method C (Example 12)

In the process (3) mentioned above, except that 1.0 mass% of sodium sulfate and 5.0 mass of sodium sulfate are added as grinding | pulverization adjuvant at the time of kneading, and the whole quantity (1 mass%) of (D) component was added at the process (2), it is manufactured. In the same manner as in Method A, a granular detergent composition was obtained.

Manufacturing Method D (Comparative Example 5)

In the above-mentioned step (3), 1.0 mass% of sodium sulfate at the time of kneading, 5.0 mass% of sodium sulfate as a grinding aid, and 1.0 mass% of sodium sulfate as a surface modifier in the above-mentioned process (4) except manufacturing method A and In the same manner, a granular detergent composition was obtained.

Manufacturing Method E (Example 12)

Except not using a nonionic surfactant, it carried out similarly to the manufacturing method A, and obtained the granular detergent composition.

Manufacturing Method F (Example 13)

A granular detergent composition was obtained in the same manner as in Production Method A except that the amount of the nonionic surfactant added (in Step (3) above) was increased according to the following Composition Table 3.

In another comparative example, the detergent composition was obtained according to the manufacturing method A, without using the unnecessary thing according to the following composition table 4, or adjusting the compounding quantity of a specific component.

In addition, in the comparative example 1, sodium sulfite was added at the time of simultaneous addition of the pulverized object, (A) component, (B) component, CMC, and OBS granulated material in the process (4) mentioned above.

<Evaluation of Detergent Composition>

(1) Evaluation of cleaning power, dullness improvement and whiteness retention

(Evaluation gun)

As a test cloth for washing power, wet artificial stains (made by Korea Foundation of Laundry Science, 28.3% of oleic acid, 15.6% of triolein, 12.2% of cholesterol oleate, 2.5% of liquid paraffin, 2.5% of squalene, 1.6% of cholesterol, 7.0% of gelatin) , Muddy 29.8%, carbon black 0.5%) 5 x 5 cm was prepared.

As an evaluation cloth for maintaining the degree of whiteness, the undershirt (100% cotton, G0134TS made by BVD company) and the stretch broad shirt (unique, polyester / cotton / polyurethane = 62/32/4) were pretreated and 5 × 5 cm Prepared by cutting.

(Charge cloth)

As a cloth for matching the bath ratio at the time of washing | cleaning, the undershirt (100% of cotton, G0134TS by the BVD company) was pre-processed, and what cut | judged to 3x3 cm was prepared.

(Pretreatment method)

Using 2 tank type washing machine (VH-30S, Toshiba Corporation), 1 kg of whiteness retention evaluation cloth or charge cloth was used for 30 liters of tap water at 50 ° C, 0.025% POE alkyl ether (ECOROL26 (an alcohol having an alkyl group having 12 to 16 carbon atoms manufactured by ECOGREEN). Ethylene oxide average 15 mole adduct)) for 15 minutes. After dehydrating for 1 minute, it washed and dehydrated again similarly. After washing, rinsing with 30 liters of tap water at 50 ° C. for 15 minutes, dehydration for 1 minute was repeated 5 times, and air-dried.

(washing)

Using a round lister (FI-301, Tester Industry Co., Ltd.), 200 ml of a 0.15% detergent solution adjusted to 25 ° C hard water at 25 ° C was placed in a stainless steel sample bottle (500 ± 50 ml). 10 pieces of evaluation cloths for washing power, 5 pieces of evaluation cloths for maintaining whiteness retention, 5 pieces of charging cloths were added, and the bath ratio was set to 10 times, and washed at 40 rpm and 25 ° C. for 25 minutes. The solution after this washing | cleaning was used for the evaluation of darkening improvement.

(rinsing)

After the washed cloth was dehydrated for 1 minute, 25 ° C of 3 ° DH hard water was returned to a sample bottle containing 200 ml, and rinsed at 40 rpm and 25 ° C for 3 minutes. This rinse process was repeated twice.

(dry)

After the rinsed cloth was dehydrated for 1 minute, the cleaning power evaluation cloth and the whiteness maintenance evaluation cloth were taken out, and the resultant was put on a filter paper and dried.

(1-1) Washing power evaluation

After drying the said cleaning power evaluation cloth with iron, the reflectance was measured using the color-difference meter (Japan Color Industry Co., Ltd., the spectroscopic color difference meter SE2000), and the cleaning rate was calculated | required by the Kubelka Mulk formula represented by the following formula. In addition, evaluation of the washing | cleaning power was performed with the average value of ten test cloths.

(In the formula, a dirt cloth, the said wet artificial dirt cloth, a washing cloth, the cloth after wash | cleaning the dirt cloth, and a miogogak represent the original white cloth (original fiber) which did not get dirt, respectively. Is the extinction coefficient, S is the scattering coefficient, and R is the transfer reflectance.)

After calculating the washing rate (%) by the above formula, the washing power was evaluated according to the following criteria.

◎◎: 81-100

◎: 66 to 80

○: 51 to 65

△: 26 to 50

× 0 to 25

(Less than one decimal point round off)

(1-2) Evaluation of dullness improvement

In order to remove the fluff in the solution after washing for the improvement of dullness, after filtering with a 355 µm sieve, L ^* of the solution was measured by a color difference meter (Japan Color Industry, Spectrophotometer SE 2000, glass cell 10 × 35 × 45 mm use, permeation) was used, and the darkness improvement was evaluated according to the following criteria.

◎◎: 71 or more

◎: 61 to 70

○: 51 to 60

△: 41 to 50

×: 40 or less

(Less than one decimal point round off)

(1-3) Whiteness retention evaluation

The washing-rinsing-drying process is repeated five times (wet a new artificial pollutant is added each time), and the reflectance of the natural dry whiteness retention test cloth is measured by a white colorimeter (Japan Color Industry, Spectrophotometer PF 10). ), It calculated as WB value (UVin), and calculated | required (DELTA) WB value by subtracting the value after washing from the value before washing. In addition, evaluation of the whiteness retention was performed at an average value of five pieces for each test cloth. Whiteness retention was evaluated based on the following criteria.

◎◎: 2 or less

◎: greater than 2 and less than 4

○: greater than 4 and less than 6

△: greater than 6 and less than 8

×: greater than 8

(2) Evaluation of color retention

(Evaluation gun)

As evaluation cloth of color retention, the thing which pretreated the dark blue shirt (BVD company, 100% cotton) and cut it to 5x5 cm was prepared.

(Charge Po)

As a cloth for adjusting the bathing ratio at the time of washing | cleaning, the undershirt (BVD company make, 100% cotton, G0134TS) was pretreated, and the thing cut | judged to 3x3 cm was prepared.

(Pretreatment method)

Using 2 tank type washing machine (VH-30S, product made by Toshiba Corporation), 1 kg of color tone retention cloth was used for 30 liters of tap water at 50 ° C, 0.025% POE alkyl ether (ECOROL 26 (an alcohol having an alkyl group having 12 to 16 carbon atoms manufactured by ECOGREEN). 15 minutes of ethylene oxide average 15 mole adduct). After dehydrating for 1 minute, it washed and dehydrated again similarly. After washing, rinsing with 30 liters of tap water at 50 ° C. for 15 minutes, dehydration for 1 minute, was repeated 5 times, and air dried.

(washing)

Using a roundley tester (FI-301, Tester Industries Co., Ltd.), 200 ml of a 0.15% detergent solution adjusted to 25 ° C. hard water at 25 ° C. was placed in a stainless steel sample bottle (500 ± 50 ml). Five pieces of evaluation cloths of color retention were added, and further, a charge cloth was placed, the bath ratio was adjusted to 10 times, and washed at 40 rpm and 25 ° C. for 25 minutes.

(rinsing)

After the washed cloth was dehydrated for 1 minute, 25 ° C. 3 ° DH hard water was returned to a sample bottle containing 200 ml, and the mixture was boiled at 40 rpm and 25 ° C. for 3 minutes. This rinse process was repeated twice.

(dry)

The rinsed cloth was dehydrated for 1 minute and then naturally dried using the laundry dryers.

The washing-rinse-drying process was repeated five times, and the discoloration degree of the evaluation cloth before and after washing was measured using a color difference meter (Japan Color Industry, Spectroscopic Colorimeter SE 2000), and as ΔE ^* ab. Calculated. In addition, the average of test 5 sheets was evaluated by the following criteria.

◎◎: 0 to less than 0.5

◎: 0.5 to less than 1.5

○: less than 1.5 to 3.0

△: less than 3.0 to 6.0

×: 6.0 or more

(3) Evaluation of repose angle

(Angle angle measurement method)

The scale of the angle was filled in, and the acrylic measuring instrument (for example, 10 cm in height x 10 cm in depth x 3 cm in width, etc.) with a horizontal cover was placed on a flat place, and the horizontal cover of the measuring instrument was closed. In a state, a sample is introduced from a height of 1 to 2 cm upward from the upper surface of the measuring device, and filled into a shape that is awkward from the top of the measuring device to a position of about 0 to 1 cm below. The shroud is then opened silently and the filled sample is naturally discharged by gravity. Thereafter, the angle (inclined angle) at which the surface of the sample remaining in the measuring device and the horizontal plane were formed was read from the scale to set the angle of repose (°).

In addition, the measuring device used that the horizontal cover is provided in one side of the side which height and width make, and the scale of an angle is written in the side which a height and depth make.

The angle of repose was evaluated according to the following criteria.

◎◎: 50 ° or less

◎: greater than 50 ° and less than 60 °

○: greater than 60 ° and less than 65 °

△: greater than 65 ° and 70 ° or less

×: greater than 70 °

[0085]

Table 1: Composition Table 1 of Detergent Composition

A component compounding quantity shows the mass% all.

Table 2: Composition Table 2 of Detergent Composition

A component compounding quantity shows the mass% all.

Table 3: Composition Table 3 of Detergent Composition

A component compounding quantity shows the mass% all.

Table 3: Composition Table 4 of Detergent Composition

A component compounding quantity shows the mass% all.

Claims (5)

(A) sodium percarbonate,
(B) hydrogen carbonate alkali metal salt,
(C) alkali metal carbonate salt,
(D) aluminosilicates and
(E) surfactant
As a medical detergent composition containing the, content of (B) component is 20 mass% or more with respect to the gross mass of the composition, content of (D) component is 10 mass% or less with respect to the gross mass of the composition, , the weight ratio of bicarbonate to carbonate sogeun muscle _{^{(HCO 3 - / CO 3 2}} -) is the medical detergent composition, characterized in that not less than 0.9. The method of claim 1,
10-30 mass% of (C) component, 1-10 mass% of (D) component, and 10-30 mass% of (E) component with respect to the gross mass of this composition, The medical detergent composition characterized by the above-mentioned. . The method of claim 1,
Moreover, (F) medical detergent composition containing 1 type (s) or 2 or more types chosen from anionic water-soluble and / or semi-disperse fluorescent brightener, and a water-insoluble blue pigment. 4. The method according to any one of claims 1 to 3,
Moreover, (G) cellulase contains a medical detergent composition characterized by the above-mentioned. The method of claim 3,
(F) A component is an anionic semi-dispersive fluorescent brightener, The medical detergent composition characterized by the above-mentioned.