KR102294485B1 - Pumping type toothpaste composition - Google Patents

Abstract

The present invention relates to a pump-type toothpaste composition that can be provided by being supported in a pump-type container.

Description

Pumping type toothpaste composition

The present invention relates to a toothpaste composition, to a toothpaste composition for being provided by being supported in a pump-type container, and to a toothpaste composition having a transparent formulation.

Toothpaste compositions commonly used for cleaning the oral cavity and teeth are products in paste, powder, gel/mucus or liquid form, and there are certain advantages and disadvantages in their use and handling.

The paste-type toothpaste first developed by Colgate in the United States was sold in an aluminum tube, and this aluminum tube was used until the 1970s. The development of aluminum as a laminated film material for such a paste-like toothpaste container as in modern times can be said to have been made with the development of polymer and polymer processing technology. However, this tube-type toothpaste has a high viscosity and is highly likely to cause damage to the tooth enamel layer due to the abrasive component. The reality is that there are many inconveniences such as problems that cause environmental pollution. In order to improve the loosening properties of the toothpaste, a liquid toothpaste product having flow properties has been released, but if it flows too well, it flows over the toothbrush and it is difficult to effectively deliver the drug to the teeth and gums in the toothpaste product. Therefore, it is widely used as an oral gargle that performs the functions of inhibiting oral bacteria and removing bad breath, but due to the lack of cleaning ingredients and the problem of easily flowing down, sufficient effects of brushing teeth such as removal of plaque and oral bacteria in the oral cavity could not be exhibited. An attempt was made to discharge high-viscosity paste by applying a vacuum pump-type plastic container to improve user convenience. characteristics and so on. In addition, the powder form is inconvenient in use because the particles are sprayed or scattered during use.

In addition, in the case of conventional tube-type toothpaste, it is contained in an opaque tube and distributed, so transparency at a transparent level when discharged on the toothbrush is sufficient. It had to be visible, so it was necessary to greatly increase the transparency.

However, it was still difficult to achieve sufficient transparency only by using a silica-based abrasive, a method that has been used to prepare a conventional transparent toothpaste composition, as a main abrasive, and mixing the refractive index of the abrasive and the refractive index of the added components to make it appear transparent. .

Republic of Korea Patent Publication No. 10-2016-0029434

Therefore, the problem to be solved by the present invention is to provide a pump-type transparent toothpaste composition that can be provided by being supported in a pump-type container and solving the above-mentioned problems.

In addition, as a pump-type transparent toothpaste composition, it is to provide a toothpaste composition of a transparent formulation while including an abrasive.

In order to solve the above problems, the present invention provides a pump-type transparent toothpaste composition that can be provided by being supported in a pump-type container. More specifically, as a pump type transparent toothpaste composition, it provides a toothpaste composition of a transparent formulation.

Hereinafter, it will be described in more detail.

The present inventors, in a pump-type transparent toothpaste composition supported in a pump-type container, include an abrasive having a refractive index of 1.420-1.465, and a surfactant having HLB 12 or more, more preferably HLB 12-23, and most preferably HLB 14-23 It was confirmed that the pump-type transparent toothpaste composition of a transparent formulation can be prepared when the fragrance is solubilized and used, and the present invention has been completed.

In the specification according to the present invention, the term 'pump type' refers to a structure in which the contents stored in the container can be simply discharged to the outside through the outlet through the pump action using the pressing part of the container. Specifically, it means a structure in which the toothpaste composition in the container is discharged to the outside of the container through the pump action of the piston, that is, the contents are transferred from the inner bottom of the container to the outside by the piston mounted inside the container by the pump action. can be emitted.

The transparent pump-type toothpaste composition according to the present invention is provided, for example, in the form of a gel.

In the specification according to the present invention, the term 'gel' is used as a concept to distinguish it from the existing liquid toothpaste of a thin formulation and a paste toothpaste of high viscosity. The gel phase is a formulation that is different from the existing liquid formulation, and it means a formulation having a high degree of stickiness and viscosity compared to a liquid toothpaste. The gel toothpaste of the present invention has elasticity and refers to a formulation with firmness compared to liquid toothpaste. In addition, the gel toothpaste of the present invention has a lower viscosity than a paste-type toothpaste, and thus has fluidity and flowability, so that the contents can be easily discharged to the outside.

In the specification according to the present invention, the term 'elasticity' refers to the property of an object deformed by an external force to return to its original shape when the force is removed. used as a broad concept meaning That is, it was used in a broad sense including all the properties of trying to maintain the original shape after discharging the toothpaste composition from the outlet.

The present invention is a pump-type transparent toothpaste composition supported in a pump-type container, a pump comprising an abrasive having a refractive index of 1.420-1.465 and a solubilizer of HLB 12 or more, preferably HLB 12-23, more preferably HLB 14-23 A type transparent toothpaste composition is provided.

In the present invention, the 'abrasive' is a material having a function of removing plaque (plaque) in the oral cavity, and is essentially used to increase the removal efficiency of dental plaque and remove hard foreign substances, etc., which are included in the present invention. The abrasive preferably has a refractive index of 1.42-1.465.

The component of the cosmetic composition and the content of the component may be determined so that the refractive index of the abrasive and the refractive index of the liquid raw material are substantially matched, and the refractive index may be measured by any known method for measuring the refractive index, for example, an immersion refractometer. It may be by a method of using a method or a method of measuring a concentration exhibiting a light transmittance of 70% or more by using a spectrophotometer, but is not limited thereto.

In the present invention, the 'refractive index and refractive index substantially coincide' means that the difference between the two refractive indices is less than 1, less than 0.5, less than 0.1, less than 0.01, less than 0.001, and most preferably 0.

The abrasive may be included as long as it is used as an abrasive of a toothpaste composition in the art without departing from the range of refractive index, for example, precipitated silica, fumed silica, colloidal silica, calcium monohydrogen phosphate, zeolite, calcium carbonate, hydrous alumina, It includes kaolin, cellulose, and mixtures thereof, and preferably silica-based abrasives such as precipitated silica, fumed silica, and colloidal silica can be used.

The content of the abrasive is 5 to 18% by weight based on the total weight of the composition. If the content of the abrasive is less than 5% by weight, the toothpaste does not exhibit abrasiveness and does not have plaque cleaning power, and if it exceeds 18% by weight, it may be difficult to discharge the toothpaste composition from the pumping container.

In the present invention, the pump-type transparent toothpaste composition may further include a refractive index adjusting agent, and the refractive index adjusting agent is included to make the refractive index of the abrasive and the refractive index of the cosmetic composition similar, for example, polyethylene glycol, propylene glycol, glycerin. , erythritol, xylitol, sorbitol, mannitol, lactitol, hydrogenated starch hydrolyzate, or a mixture thereof, preferably glycerin, but is not limited thereto.

In the present invention, the pump-type transparent toothpaste composition may further include a refractive agent and water, and preferably, the weight ratio of the refractive regulator and water is 65:35 to 90:10. In addition, the weight ratio of the abrasive, the refractive agent, and the water is 10-15:60-80:5-30, preferably 10-15:60-75:10-20, most preferably, the abrasive: the refractive agent: water. is 14:65-70:16-21. The weight ratio is a preferred weight ratio for making the refractive index of the liquid raw material of the toothpaste composition similar to the solid component such as an abrasive, and when it is out of the range of the weight ratio, the transparent formulation desired by the present invention is not implemented.

The transparent pump-type toothpaste composition according to the present invention includes a solubilizer, and the solubilizing agent is preferably a surfactant having HLB 12 or higher, more preferably a surfactant having HLB 12-23, and most preferably a surfactant having HLB 14-23. Use an activator.

In the present invention, the solubilizing agent is a material for solubilizing a material having low solubility in water, preferably HLB 12 or more, more preferably HLB 12-23, most preferably HLB 14-23 surfactant. use.

The HLB (Hydrophile-Lipophile Balance) is a value indicating the affinity of the surfactant to water and oil, and the HLB indicates that the smaller the value, the stronger the lipophilicity as a whole molecule, and the larger the value, the stronger the hydrophilicity. . The HLB formula is as follows:

HLB = 20 x molecular weight of hydrophilic groups / total molecular weight

Any surfactant having HLB 12 or higher, preferably HLB 12-23, more preferably HLB 14-23, which is known in the art to be used in toothpaste compositions, may be used as a solubilizer, for example, polyglyceryl -3 Methylglucose distearate, oleth-10, oleth-10/polyoxyl 10 oleyl ester NF, cereth-10, PEG-8 laurate, cocamite MEA, polyoxyethylene hydrogenated castor oil-40 (HCO 40), polyoxyethylene hydrogenated castor oil-60 (HCO 60), poloxamer 184, poloxamer 407 or mixtures thereof, etc. are included, preferably polyoxyethylene hydrogenated castor oil-40 (HCO). 40), poloxamer 407 or mixtures thereof may be used.

The present inventors confirmed that the effect of the invention, particularly transparency, was the best when HCO 40, poloxamer 407 alone or a mixture thereof was used as the solubilizing agent.

The HCO 40 is a nonionic surfactant, and can be prepared by various methods known in the art, for example, it can be synthesized by addition polymerization of ethylene oxide (EO) to hydrogenated castor oil in which hydrogen is added to the double bond of castor oil. Alternatively, commercially available products may be used.

The poloxamer 407 is a nonionic surfactant, and is a PEG-PPG-PEG block copolymer having a polyoxypropylene molecular mass of 4,000 g/mol and a 70% PEG (polyoxyethylene) content.

In addition, the content of the solubilizer may include 0.7 to 3% by weight, preferably 1 to 2.5% by weight, more preferably 1.3 to 2.2% by weight relative to the total weight of the composition. When the solubilizer is used in an amount within the above range, a toothpaste composition of a transparent formulation can be prepared.

The content of the abrasive contained in the toothpaste composition of the transparent formulation is 5 to 18% by weight relative to the total weight of the composition, the content of the water-insoluble component is 0.5 to 3.0% by weight relative to the total weight of the composition, and the content of the solubilizer is 0.7 to 18% by weight relative to the total weight of the composition 3% by weight.

The weight ratio of the water-insoluble component and the solubilizing agent may be 1:1-2.5 of the water-insoluble component: the solubilizing agent. Also, the water-insoluble component: solubilizer may be 1:1-6 (when the content of the water-insoluble component is 0.5% by weight and the content of the solubilizer is 3% by weight, the water-insoluble component:the solubilizer is 1:6).

The toothpaste composition according to the present invention may further include components commonly used in toothpaste compositions in the art within a range that does not impair the purpose of the present invention. For example, it may further include a flavoring agent, a sweetener, a medicinal agent, a pH adjuster, a preservative, a binder, a foaming agent, a brightening agent, and the like.

Preferably, the toothpaste composition according to the present invention is provided as a pump-type transparent toothpaste composition, and preferably includes a hydrophilic colloid containing carboxymethyl cellulose, sodium alginate, xanthan gum or a mixture thereof, and the discharge port is blocked by drying It is preferable to include a lubricant (polyol, etc.) to prevent development. In addition, water-insoluble ingredients including flavoring, vitamin E, or mixtures thereof may be included.

The hydrophilic colloid can impart an appropriate viscosity of the toothpaste, and the lubricant refers to a substance that reduces friction between two surfaces sliding in contact with each other, and the lubricant acts as a lubricant and is contained in the toothpaste composition of the present invention It plays a role in preventing piston wear caused by raw materials (solids such as abrasives) that show the wear characteristics. The lubricant may include, for example, any one selected from the group consisting of polyethylene glycol, glycerol, propylene glycol, ethylene glycol, polypropylene glycol, and mixtures thereof, but is not limited thereto. Preferably, it may include any one selected from the group consisting of polyethylene glycol 200 to 600, glycerol, propylene glycol, ethylene glycol, polypropylene glycol, and mixtures thereof. Preferably, as the liquid lubricant, petroleum oil, animal or vegetable oil, synthetic lubricant, etc. may be used, and most preferably, polyol, glycerin, or a mixture thereof may be used in terms of stability and excellent feeling of use of the composition.

Flavors and sweeteners may be added to the composition of the present invention to suit consumer preferences. The fragrance is solubilized by the solubilizing agent to reveal the transparent formulation of the present invention, and to remain in the oral cavity and to continuously emit a fragrance to maintain a refreshing feeling.

The fragrance may be peppermint, mint such as spearmint, winter green, methyl salicylate, eugenol, melon, strawberry, orange, vanillin, and the like. In general, the content of the fragrance may be used in the range of 0.001 to 5% by weight based on the total weight of the composition.

In addition, a sweetener may be added to the composition of the present invention in order to overcome the basic taste that the formulation may have, and the sweetener may serve to sustain the generation of saliva by continuously providing a taste while remaining in the oral cavity. .

The sweetener may be one or a mixture of two or more of saccharin, sucralose, sugar, xylitol, sorbitol, lactose, mannitol, maltitol, erythritol, aspartame, taurine, saccharin salt, D-tryptophan, and the like. Among the saccharin salts, sodium saccharin is most widely used, and the content of the sweetener is generally used in the range of 0.001 to 5% by weight relative to the total weight of the composition.

The medicinal agent may be used for oral hygiene, and ingredients having effects such as prevention of tooth decay, prevention of gum disease, prevention of tartar deposition, and whitening may be used. Drugs used for the purpose of preventing tooth decay include compounds recognized as safe substances by the US Food and Drug Administration, including fluoride ions. Compounds that can be used as a source of fluoride ions include sodium fluoride, sodium monofluorophosphate, tin fluoride, and amine fluoride. The content of fluorine may vary in the amount used depending on the country, but it is common to use one or a mixture of two or more of these sources to preferably have a fluorine ion concentration in the range of 850 to 1500 ppm. Remineralizing agents can also act as a caries preventative. Remineralization plays a role in regenerating and restoring hydroxyapatite, a major component of teeth. The main components of hydroxyapatite are composed of divalent calcium cations and phosphate anions. Therefore, if calcium ions and phosphate ions are supplied at the same time or contain one or more calcium divalent ions or phosphate anions so as to move the chemical equilibrium in the oral cavity to the side where hydroxyapatite is produced, it may be a remineralizing agent. Substances providing calcium and phosphorus include hydroxyapatite, dibasic calcium phosphate, calcium chloride, casein phospeptide, calcium glycerophosphate, monosodium phosphate, dibasic sodium phosphate, trisodium phosphate, potassium monobasic, Potassium diphosphate, potassium triphosphate, and the like are included therein. In general, the content of the remineralizing agent is preferably 0.001 to 5% by weight relative to the total weight of the composition, and when the content is less than 0.001% by weight, the remineralization effect is reduced, and when it exceeds 5% by weight, the original properties of the formulation will lose One of the purposes of using oral hygiene products is to prevent gum disease in advance as well as alleviate the ongoing periodontal disease through sterilization or anti-inflammatory action on harmful microorganisms living in the oral cavity. For this purpose, isopropylmethylphenol, cyclohexidine, cetylpyridinium chloride, triclosan, xanthorizol, etc. known as antibacterial agents may be used, and for anti-inflammatory action, vitamins (eg vitamin E) and enzymes, aminocaproic acid , allatoin and its derivatives may also be used. In addition to gum disease, hydrogen peroxide, carbamide peroxide, calcium peroxide, etc., which have a whitening effect, may be used, and sodium pyrophosphate, sodium pyrophosphate, potassium pyrophosphate, sodium metaphosphate, etc. are used to obtain an effect of inhibiting tartar deposition. The active agent may include 0.005 wt% to 5 wt%. If the content is less than 0.005, it is difficult to show medicinal effect, and if it exceeds 5 wt%, there is a disadvantage of changing the taste of the basic base.

The pH adjuster may use phosphoric acid, sodium phosphate, citric acid, sodium citrate, succinic acid, sodium succinate, tartaric acid, sodium tartrate, and the like, and the acidity of the oral composition is generally pH 5 to 8.

The preservative may include benzoic acid, methylparaben, propylparaben, sodium benzoate, and the like.

The binder may be any one selected from the group consisting of sodium carboxymethylcellulose, carbomer, carrageenan, xanthan gum, water-soluble polyvinyl acrylic resin, silica for thickening, aluminum silicate, polyacrylate, and mixtures thereof. These binders may be used alone or in combination of two or more, preferably xanthan gum.

The foaming agent is sodium alkyl sulfate, sodium lauryl sulfate, alkyl salucosinate, lauryl salucosinate, cocoyl glutamate sodium salt, myrisritoyl glutamate sodium salt, cocamidopropyl betaine, sucrose fatty acid ester, sorbitan fatty acid ester , an anionic, amphoteric and nonionic surfactant such as a copolymer (poloxamer) of polyoxyethylene polyoxypropylene can be used alone or in combination of two or more.

Titanium oxide is used as the brightener and is generally used in an amount of 0.1% to 2% by weight.

The toothpaste composition according to the present invention is provided as a pump-type transparent toothpaste composition, and preferably contains a water-insoluble component including flavoring, vitamin E, or a mixture thereof.

In addition, the method for preparing the toothpaste composition of the present invention may be prepared according to a method prepared in the art.

Preferably, the present invention provides a method for producing a pump-type transparent toothpaste composition in which a solubilizer is put into the water-insoluble component and mixed first, and the abrasive and optionally a medicinal agent are mixed secondarily.

The toothpaste composition according to the present invention may be used as a mouthwash, a denture cleaner, and the like.

The transparent pump-type toothpaste composition according to the present invention is provided while being supported in a pump-type container.

The present invention provides a pump-type transparent toothpaste comprising the above-described transparent pump-type toothpaste composition, and a pump-type container in which the pump-type transparent toothpaste composition is supported.

In addition, the present invention provides a pump-type transparent toothpaste, wherein the pump-type container is a pump-type transparent container.

According to the present invention, a pump-type transparent toothpaste composition that can be provided by being supported in a pump-type container is provided, and in particular, a toothpaste composition having excellent commercial value in a transparent formulation despite containing an abrasive is provided.

The following drawings attached to the present specification illustrate preferred embodiments of the present invention, and serve to further understand the technical spirit of the present invention together with the above-described content of the present invention, so the present invention is limited to the matters described in those drawings It should not be construed as being limited.
1 is a graph showing the refractive index according to the content of glycerin in water in the pump-type transparent toothpaste composition according to the present invention.

Hereinafter, examples and the like will be described in detail to help the understanding of the present invention. However, the embodiments according to the present invention may be modified in various other forms, and the scope of the present invention should not be construed as being limited to the following examples. The embodiments of the present invention are provided to more completely explain the present invention to those of ordinary skill in the art to which the present invention pertains.

Preparation of Examples 1-3 and Comparative Examples 1-4

The toothpaste compositions of Examples and Comparative Examples were prepared with the ingredients and weights shown in Table 1 below. For example, the remaining components except for the abrasive and optionally the medicinal agent are first mixed, and at this time, the fragrance and vitamin E, which are insoluble components, are first mixed by putting together HCO 40, poloxamer 407 or a mixture thereof, which are solubilizers. Then, an abrasive such as silica and optionally a medicinal agent were added, and a toothpaste composition was prepared by secondary mixing under vacuum. However, in the preparation of Comparative Example 1 without using a solubilizer, it was prepared without a primary mixing process.

Example 1 Example 2 Example 3 Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Precipitated Silica 14 14 14 14 5 5 5 glycerin 62 62 62 62 45 45 45 Sodium Lauryl Sulfate 1.00 1.00 1.00 1.00 1.00 1.00 1.00 HCO40 2.00 0 1.10 0 1.10 2.00 0 Poloxamer 407 0 2.00 1.10 0 1.10 0 2.00 Saccharin Sodium 0.20 0.20 0.20 0.20 0.20 0.20 0.20 Xanthan Gum 1.00 1.00 1.00 1.00 1.00 1.00 1.00 sodium fluoride 0.22 0.22 0.22 0.22 0.22 0.22 0.22 vitamin E 0.20 0.20 0.20 0.20 0.20 0.20 0.20 Spices 0.50 0.50 0.50 0.50 0.50 0.50 0.50 Purified water 18.88 18.88 18.68 20.88 44.68 44.88 44.88

Transparency comparison of toothpaste With respect to the toothpaste prepared as in Examples 1-3 and Comparative Example 1-4 of Table 1, the toothpaste was put into a transparent petri dish to a thickness of 1 cm, and the transparency of the toothpaste was readability for 10 points of the word background. was judged. The results are shown in Table 2.

The evaluation of readability is based on how a group of 5 evaluators read characters accurately, 'opaque' when it is impossible to identify characters to some extent, 'slightly transparent' when characters can be identified but not clear, and characters without discomfort. A case in which . can be identified was judged as 'transparent'.

Example 1 Example 2 Example 3 Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 transparency Transparency Transparency Transparency slightly transparent opacity opacity opacity

The refractive index of the abrasive was made similar to that of the liquid raw material, but Comparative Example 1, which did not contain the solubilizer, showed a slightly transparent degree, whereas Comparative Examples 2-4, which did not make the refractive index of the abrasive and the liquid raw material similar, contained a solubilizing agent. In spite of the inclusion, it was opaque, the refractive index of the abrasive and the liquid raw material were similar, and Examples 1-3 in which the insoluble component, especially the fragrance, were solubilized through the solubilizer, were transparent. Through this, even in the toothpaste composition including the abrasive, when the refractive index of the abrasive is similar to that of the liquid raw material, and the insoluble component including the fragrance is solubilized by the solubilizing agent, it was confirmed that the transparency of the formulation is increased.

Confirmation of refractive index according to the content of glycerin

The refractive index according to the content of glycerin with respect to water is shown in FIG. 1 . Referring to the fact that the refractive index of silica (Solvay, Tixosil73K) is 1.437 and FIG. 1, when 14 wt% of silica is used, the content of glycerin with respect to water, which can make the refractive index of the liquid raw material similar, is 76%. Therefore, when 14 wt% of silica, 62 wt% of glycerin, and about 19 wt% of water were used, the refractive index between the components of the toothpaste composition was set to a similar degree, and it was confirmed that the transparency of the toothpaste was improved.

Claims (10)

As a gel-like pump-type transparent toothpaste composition supported in a pump-type container,
abrasives having a refractive index of 1.42-1.465; non-aqueous ingredients including perfume; and a surfactant having HLB 12-23 as an essential component as a solubilizer,
The weight ratio of the water-insoluble component and the solubilizer is a pump-type transparent toothpaste composition, characterized in that the water-insoluble component: the solubilizer is 1:1-6. delete The pump-type transparent toothpaste composition according to claim 1, wherein the weight ratio of the water-insoluble component and the solubilizer is 1:1-2.5 of the water-insoluble component: the solubilizer. According to claim 1, wherein the abrasive is a pump-type transparent toothpaste composition, characterized in that any one selected from the group consisting of precipitated silica, fumed silica, colloidal silica, and mixtures thereof. According to claim 1, wherein the solubilizer is polyoxyethylene hydrogenated castor oil, poloxamer, and a transparent pump type toothpaste composition, characterized in that at least one selected from the group consisting of mixtures thereof. According to claim 1, wherein the content of the abrasive is 5 to 18% by weight based on the total weight of the composition, and the content of the water-insoluble component is 0.5 to 3.0% by weight based on the total weight of the composition. According to claim 1, wherein the content of the solubilizer is a pump-type transparent toothpaste composition, characterized in that 0.7 to 3% by weight based on the total weight of the composition. As a method for producing a pump-type transparent toothpaste composition according to any one of claims 1 and 3 to 7,
First mixing by putting a solubilizer in the water-insoluble component; and adding the abrasive and second mixing in a vacuum state. A transparent pump-type toothpaste comprising a pump-type transparent toothpaste composition according to any one of claims 1 and 3 to 7, and a pump-type container in which the pump-type transparent toothpaste composition is supported. 10. The transparent pump-type toothpaste of claim 9, wherein the pump-type container is a transparent container.

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