KR102262791B1 - A composition for improving skin function comprising fermented herb extracts - Google Patents
A composition for improving skin function comprising fermented herb extracts Download PDFInfo
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- KR102262791B1 KR102262791B1 KR1020190115952A KR20190115952A KR102262791B1 KR 102262791 B1 KR102262791 B1 KR 102262791B1 KR 1020190115952 A KR1020190115952 A KR 1020190115952A KR 20190115952 A KR20190115952 A KR 20190115952A KR 102262791 B1 KR102262791 B1 KR 102262791B1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
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- Epidemiology (AREA)
- Mycology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
본 발명은 이와 같이, 본 발명은 행인, 양제근, 접골목, 천문동, 감초 , 석죽 , 산자고 추출 발효물 포함하는 피부 기능 개선을 위한 화장료 조성물을 제공한다.
본 발명은 피부 기능 개선효과 및 피부노화 방지 효과가 우수하고, 안전성 및 안정성이 높아 피부 부작용이 없는 천연유래 화장품 소재를 개발하고자 노력하여 천연 한방소재를 이용하여 아토피 등 각종 피부질환에 유용한 효과를 제공한다.As described above, the present invention provides a cosmetic composition for improving skin function, including fermented fermented passers-by, yangjegeun, osteophyte, cheonmundong, licorice, seokjuk, and sanjago extract.
The present invention strives to develop a naturally-derived cosmetic material that has excellent skin function improvement effect and skin aging prevention effect, and has no skin side effects due to high safety and stability, and provides useful effects for various skin diseases such as atopy using natural oriental medicinal materials do.
Description
본 발명은 한방 발효물을 포함하는 피부 개선을 위한 조성물에 관한 것으로, 보다 구체적으로는 행인, 양제근, 접골목, 천문동, 감초 , 석죽 , 산자고 추출 발효물 포함하는 피부 기능 개선을 위한 화장료 조성물에 관한 것이다. The present invention relates to a composition for improving skin comprising a fermented oriental medicine, and more particularly, to a cosmetic composition for improving skin function, including a fermented product extracted from passers-by, Yangjegeun, osteophyte, Cheonmundong, licorice, Seokjuk, and Sanjago. will be.
피부는 신체를 둘러쌓고 있는 조직으로 얇은 두께 안에 실핏줄을 포함하여 수많은 세포들이 외부의 환경과 서로 접하며 상호작용을 하고 있다.The skin is a tissue surrounding the body, and in a thin thickness, numerous cells, including blood vessels, are in contact with the external environment and interact with each other.
최근에는 피부를 통해 기능성 물질을 흡수시키면 피부에 넓게 퍼져있는 실핏줄을 통해 신속한 효능을 나타낸다는 사실에 주목하여 마스크팩, 로션 등 각종 피부개선 제품들이 개발되고 있다.Recently, various skin improvement products such as mask packs and lotions have been developed, paying attention to the fact that when functional substances are absorbed through the skin, they show rapid efficacy through the blood vessels that are widely spread on the skin.
한편, 피부는 노화가 지속적으로 일어나는데 통상적으로 피부노화는 25세를 전후하여 진행되기 시작하여 40세를 전후한 시기에 본격적으로 피부노화가 진행되고 각종 피부질환에 노출되는데, 화장품 분야에서는 피부 개선효과를 가지는 기능성 화장품에 대한 연구 및 개발이 활발하게 진행되고 있으며, 특히 피부에 독성이나 자극을 주지 않기 위하여 천연 물질을 이용한 연구가 계속되고 있다.On the other hand, skin aging occurs continuously, and skin aging usually starts around the age of 25, and skin aging progresses in earnest around the age of 40 and is exposed to various skin diseases. Research and development of functional cosmetics with
이에 본 발명자들은 피부 기능 개선효과 및 피부노화 방지 효과가 우수하고 안전성 및 안정성이 높아 피부 부작용이 없는 천연유래 화장품 소재를 개발하고자 노력하여 천연 한방소재를 이용하여 아토피 등 각종 피부질환에 유용한 한방 발효물을 포함하는 피부 개선을 위한 조성물 발명을 완성하였다.Accordingly, the present inventors have endeavored to develop a natural cosmetic material that has excellent skin function improvement and skin aging prevention effects, and has no skin side effects due to high safety and stability, and uses natural oriental medicinal materials to treat various skin diseases such as atopy. Completed the invention of a composition for skin improvement comprising a.
따라서, 본 발명에서 해결하고자 하는 기술적 과제는 천연소재인 행인, 양제근, 접골목, 천문동, 감초 , 석죽 , 산자고 혼합추출물의 발효 발효추출물을 포함하는 피부 기능 개선을 위한 조성물을 제공하기 위한 것이다. Therefore, the technical problem to be solved in the present invention is to provide a composition for improving skin function, comprising a fermented fermented extract of natural materials such as passerby, yangjegeun, osteophyte, cheonmundong, licorice, seokjuk, and sanjago mixed extract It is to provide a composition.
상기한 기술적 과제를 해결하기 위하여, 본 발명에서는 행인, 양제근, 접골목, 천문동, 감초 , 석죽 , 산자고 혼합 추출물의 발효추출물 포함하는 피부 기능 개선을 위한 화장료 조성물을 제공한다.In order to solve the above technical problem, the present invention provides a cosmetic composition for improving skin function, including a fermented extract of passers-by, Yangjegeun, osteophyte, Cheonmundong, licorice, Seokjuk, and Sanjago mixed extract.
바람직한 하나의 구현예에 따르면, 본 발명에서는 행인 20중량%, 양제근 15중량%, 접골목 15중량%, 천문동 20중량%, 감초 10중량% , 석죽 3중량% , 산자고 5중량% 로 이루어진 혼합 추출물의 발효물을 포함하는 피부 기능 개선을 위한 화장료 조성물을 제공한다.According to one preferred embodiment, in the present invention, 20% by weight of passersby, 15% by weight of Yangjegeun, 15% by weight of osteophytes, 20% by weight of Cheonmundong, 10% by weight of licorice, 3% by weight of stone bamboo, 5% by weight of Sanjago It provides a cosmetic composition for improving skin function comprising a fermented product of
본 발명은 행인, 양제근, 접골목, 천문동, 감초 , 석죽 , 산자고 혼합 추출물의 발효추출물 포함하는 피부 기능 개선을 위한 화장료 조성물 뿐만 아니라, 상기 발효물 포함하는 피부 기능 개선을 위한 비누 또는 세제와 로션, 크림 등 화장품으로 제형화된 모든 형태를 포함한다.The present invention provides a cosmetic composition for improving skin function including a fermented extract of passers-by, yangjegeun, osteopathy, Cheonmundong, licorice, Seokjuk, and Sanjago mixed extract, as well as a soap or detergent and lotion for improving skin function including the fermented product, Includes all forms formulated as cosmetic products, such as creams.
본 발명은 행인, 양제근, 접골목, 천문동, 감초 , 석죽 , 산자고 혼합 추출물의 자연 발효를 거친 발효액일 수 있다.The present invention may be a fermented broth that has undergone natural fermentation of a mixed extract of passers-by, Yangjegeun, zygomok, Cheonmundong, licorice, Seokjuk, and Sanjago.
또한 본 발명에 있어서, 상기 혼합추출물을 유산균 중에서 발효한 것을 의미할 수 있다. 이 때 발효균으로 유산균을 사용하며, 예를 들어, 락토바실러스 카제이(Lactobacillus casei), 락토바실러스 플란타룸(L. plantarum), 락토바실러스 애시도필러스(L. acidophilus), 락토바실러스 불가리쿠스(L.bulgaricus), 비피도박테리움 롱굼(Bifidobacterium longum), 비피도박테리움 비피둠(B. bifidum) 또는 이들의 혼합균을 사용할 수 있으며, 바람직하게는 락토바실러스 플란타룸(L. plantarum), 비피도박테리움 비피둠(B. bifidum) 또는 이들의 혼합균을 사용할 수 있으며, 특히 락토바실러스 플란타룸(L. plantarum) 및 비피도박테리움 비피둠(B. bifidum)이 바람직하다. In addition, in the present invention, it may mean that the mixed extract is fermented in lactic acid bacteria. At this time, lactic acid bacteria are used as the fermenting bacteria, for example, Lactobacillus casei (Lactobacillus casei), Lactobacillus plantarum (L. plantarum), Lactobacillus acidophilus (L. acidophilus), Lactobacillus bulgaricus (L. bulgaricus), Bifidobacterium longum (Bifidobacterium longum), Bifidobacterium Bifidum (B. bifidum ) or a mixture thereof may be used, preferably Lactobacillus plantarum (L. plantarum), Bifidobacterium bifidum (B. bifidum ) or a mixture thereof may be used and, in particular, Lactobacillus plantarum (L. plantarum) and Bifidobacterium bifidum (B. bifidum) are preferred.
본 발명의 바람직한 구현예에서, 추출 발효물은 행인, 양제근, 접골목, 천문동, 감초 , 석죽 , 산자고 혼합물의 열수 추추물에 2년이상 숙성된 발효원액을 추출물 중량을 기준으로 2 내지 7 중량%의 양으로 접종하여 10 내지 20시간 동안 배양하여 제조될 수 있다.In a preferred embodiment of the present invention, the extract fermented product is a fermented undiluted solution aged for 2 years or more in a hot water extract of a mixture of passers-by, yangjegeun, jeogolmok, Cheonmundong, licorice, Seokjuk, and Sanjago 2 to 7% by weight based on the weight of the extract. It can be prepared by inoculating in an amount of and culturing for 10 to 20 hours.
상기에서 숙성된 발효원액은 행인, 양제근, 접골목, 천문동, 감초 , 석죽 , 산자고 혼합물의 열수 추추물에 2년이상 숙성된 발효원액을 추출물 중량을 기준으로 2 내지 7 중량%의 양으로 접종하여 10 내지 20시간 동안 배양하여 제조된 발효추출액을 냉장실에서 10~20 ℃에 2년이상, 바람직하게는 2~5년간 보관하여 발효가 균질화 된 것이며 발효균이 일정하게 살아나 발효를 촉진하는 역할을 한다.The fermented undiluted solution aged above is inoculated in an amount of 2 to 7% by weight based on the weight of the extract by inoculating the fermented undiluted solution aged for more than 2 years in the hot water extract of a mixture of passers-by, Yangjegeun, jeomokok, Cheonmundong, licorice, Seokjuk, and Sanjago The fermentation extract prepared by culturing for 10 to 20 hours is stored at 10 to 20 ° C in a refrigerator for at least 2 years, preferably for 2 to 5 years, and the fermentation is homogenized, and the fermenting bacteria are constantly alive and serve to promote fermentation.
본 발명의 조성물의 용도인 피부 개선은 통상적인 피부 보호용도(주름의 예방, 주름의 제거, 피부질한, 아토피 예방 또는 치료 등)를 포함하는 것으로 해석된다.Skin improvement, which is the use of the composition of the present invention, is interpreted to include conventional skin protection purposes (prevention of wrinkles, removal of wrinkles, skin irritation, prevention or treatment of atopic dermatitis, etc.).
본 발명의 조성물의 유효성분인 행인은 뿌리를 가공한 것으로, 혈액 결핍 및 이에 따른 간과 심장의 영양 부족의 치료를 위해 사용되고, 또한 간과 신장의 음을 강하게 하는 것으로 알려져 있다. 이러한 간과 심장의 영양 부족에 따라 등 통증, 어지럼증, 현기증, 이명, 청력감퇴, 주기적인 발열, 식은땀 등의 증상이 나타난다. Haengin, an active ingredient of the composition of the present invention, is a processed root, used for the treatment of blood deficiency and consequent nutritional deficiency of the liver and heart, and is also known to strengthen the tone of the liver and kidneys. Symptoms such as back pain, dizziness, dizziness, tinnitus, hearing loss, periodic fever, and night sweats appear according to the nutritional deficiency of the liver and heart.
양재근은 비타민을 많이 함유하고 있는 식물로서, 위장병 전반에 효력이 있다. 위염, 대장염에, 쓰이며, 변비, 치질에 특효가 있으며, 강장 효과가 뛰어다. 아울러 빈혈 토혈, 혈소판 감소성 자반증 등에도 쓰인다.Yangjae-geun is a plant containing a lot of vitamins, and it is effective in general gastrointestinal diseases. It is used for gastritis and colitis, and has a special effect on constipation and hemorrhoids, and has an excellent tonic effect. It is also used for anemia, hematemesis, and thrombocytopenic purpura.
접골목은 인동과 식물인 넓은잎딱총나무 Sambucus latipinna Nakai와 딱총나무 S. latipinna Nakai var. coreana Nakai의 줄기를 말린 것이다. 각지의 산골짜기와 산기슭, 개울가에서 널리 자란다. 통증을 멎게 하고 소변이 잘 나오게 하며 출혈을 멎게 하고 염증을 잘 낫게 한다. 타박상, 골절, 류머티스성 관절염, 복수, 신염, 통풍(痛風), 목이 아픈 데, 여러 가지 출혈 등에 쓴다. 하루 5~10g을 물에 달여 3번에 나누어 먹는다. 외용약으로 쓸 때는 달인 물로 찜질한다. 딱총나무꽃은 민간에서 발한제(發汗劑) · 이뇨제로 쓴다.The osteophytes are the Hemiaceae, Sambucus latipinna Nakai, and S. latipinna Nakai var. Dried stems of coreana Nakai. It grows widely in the valleys, foothills, and streams of various places. It relieves pain, facilitates urination, stops bleeding, and relieves inflammation. It is used for bruises, fractures, rheumatoid arthritis, ascites, nephritis, gout, sore throat, and various types of bleeding. Take 5-10g a day in water and divide it into 3 servings. When used as an external medicine, poultice with decoction of water. Elderberry flowers are used in folklore as antiperspirant and diuretic.
감초는 단맛을 가지고 여러 약재를 혼합하여 사용할때 서로 융합하여 효능을 높이는 효과가 있다.Licorice has a sweet taste, and when mixed and used, it has the effect of fusion with each other to increase the efficacy.
석죽은 Dianthus chinensis의 지상부(地上部)로, 이수(利水)시키고 임증(淋症)을 치료하고 혈액(血液)의 소통을 돕고 경맥(經脈)을 통(通)하게 하는 효능을 가진다.Seokjuk is the above-ground part of Dianthus chinensis, and has the effect of hydrating water, curing nephropathy, helping blood flow, and allowing the meridians to pass through.
산자고는 백합과 식물인 까치무릇 Tulipa edulis Bak.의 비늘줄기를 말린 것으로 우리 나라 각지의 산에서 자라며, 초여름에 비늘줄기를 캐 물에 씻어 껍질을 벗겨 햇볕에 말려 사용한다. 혈액 순환을 촉진하며 어혈을 없애고 가래를 삭이며 엉기어 있는 것을 흩어지게 한다. 연주창, 옹종(癰腫), 창양(瘡瘍), 산후 어혈 등 피부조직을 풀어주는 효능이 있다.Sanjago is the dried scale stem of Tulipa edulis Bak., a plant in the lily family. It grows in the mountains of Korea. It is used in early summer by digging up the scale stem, washing it in water, peeling it, and drying it in the sun. It promotes blood circulation, removes blood stasis, removes phlegm, and disperses clumps. It has the effect of relieving skin tissues such as choichang, ongjong (癰腫), changyang (瘡瘍), postpartum eohyeol, etc.
본 발명의 행인, 양제근, 접골목, 천문동, 감초 , 석죽 , 산자고 추출 발효물 포함하는 피부 기능 개선을 위한 화장료 조성물은 천연 물질로서 세포독성이 거의 없다. The cosmetic composition for improving skin function, including fermented fermented passers-by, Yangjegeun, osteoclast, Cheonmundong, licorice, Seokjuk, and Sanjago extract of the present invention, is a natural material and has almost no cytotoxicity.
본 발명의 하나의 실시양태에 따르면, 행인 20중량%, 양제근 15중량%, 접골목 15중량%, 천문동 20중량%, 감초 10중량% , 석죽 3중량% , 산자고 5중량% 로 이루혼합 추출물의 발효를 통여 활성물질의 최적화를 가져온다. According to one embodiment of the present invention, 20% by weight of passersby, 15% by weight of yangjegeun, 15% by weight of osteophytes, 20% by weight of Cheonmundong, 10% by weight of licorice, 3% by weight of stone bamboo, 5% by weight of sanjago Optimization of active substances through fermentation.
이를 위해 원재료 입고 후 추출효능을 최대한 끌어올리기 위해 분말을 내고 1차 열수추출을 진행하며, 1차 추출 후 10일 정도 음지에 숙성시키면 자연발생 발효꽃이 피기시작하는데 발효꽃이 전체 원액의 1/3정도 발생했을 때, 2년~5년 숙성된 추출원액을 전체 추출량 대비 3%를 추가로 투입해 혼합하여 2차 열수추출과정을 거쳐 15일 정도 저온숙성하고 상온에 보관한다.To this end, to maximize the extraction efficiency after receiving the raw materials, powder is produced and the first hot water extraction is carried out. After the first extraction, if it is aged in the shade for about 10 days, naturally occurring fermented flowers begin to bloom. When the third degree occurs, an additional 3% of the extracted undiluted solution aged 2 to 5 years is added and mixed, undergoes a secondary hot water extraction process, aged at low temperature for 15 days and stored at room temperature.
이때 발효꽃은 탄수화물(전분)을 분해해서 포도당이나 과당의 단당류로 저분자화 하는 것이고 이때 중요한 누룩꽃 발생인자는 단당류인데 사용하는 약재 중에 감초나 천문동 산자고 등은 당성분을 함유하고 있어 미생물이 활성화되는데 중요한 역할을 한다. 당이 없으면 대부분의 균은 활동을 못하는데 다른 균들을 활성화시키는 최초의 균이 발효꽃을 발생시키는 누룩균다. 다양한 분자가 모인 탄수화물은 분자량이 너무 커서 다른 균들이 바로 이용할 수 없기 때문에 누룩균이 작고 먹기 쉬운 단당류로 만들어 놓으면 다른 균들도 활동하기 시작한다.At this time, fermented flowers decompose carbohydrates (starch) into low molecular weight monosaccharides such as glucose or fructose. plays an important role. Without sugar, most bacteria are inactive, but the first bacteria that activate other bacteria are yeast bacteria that generate fermented flowers. Carbohydrates with various molecules have such a large molecular weight that other bacteria cannot use them right away, so if Koji bacteria is made into small, easy-to-eat monosaccharides, other bacteria will also begin to work.
또한 누룩균 발생 후 1차 추출이 마무리되면 2차 추출 때 2년이상 숙성된 추출원액을 첨가해서 2차 추출로 들어가는데 이 원액은 이미 분자, 원자간 이동이 거의 없는 상태의 순수성을 보유하고 있으며 이 추출이 2차 추출에 들어가면 1차 추출물의 발효 및 활성화에 큰 역할을 하는데, 추출원액의 순도를 높인다.In addition, when the primary extraction is completed after the occurrence of yeast bacteria, the undiluted extract that has been aged for more than 2 years is added during the secondary extraction to proceed to the secondary extraction. This undiluted solution already possesses the purity of the state with almost no movement between molecules and atoms. When entering this secondary extraction, it plays a big role in the fermentation and activation of the primary extract, and increases the purity of the extract.
본 발명의 구체적인 실시양태에서는 행인, 양제근, 접골목, 천문동, 감초 , 석죽 , 산자고의 혼합 추출물의 발효물을 포함하는 비누를 개발하여 피부탄력 개선효과를 관찰할 수 있다.In a specific embodiment of the present invention, it is possible to observe the skin elasticity improvement effect by developing a soap containing a fermented product of a mixed extract of passers-by, yangjegeun, osteophyte, cheonmundong, licorice, seokjuk, and sanjago.
본 발명의 구체적인 실험에서는 도3에서 보는 바와같이 아토피성 피부질환의 개선효과가 현저하게 나타났다. In a specific experiment of the present invention, the improvement effect of atopic skin disease was remarkably shown as shown in FIG. 3 .
본 발명의 하나의 실시양태에 따른 화장료 조성물에는 유효성분 이외에 화장품 조성물에 통상적으로 첨가되는 성분, 예컨대 항산화제, 안정화제, 가용화제, 비타민, 안료 및 향료와 같은 통상적인 보조제, 및 담체를 추가로 첨가할 수 있다. In the cosmetic composition according to one embodiment of the present invention, in addition to the active ingredient, components commonly added to the cosmetic composition, such as antioxidants, stabilizers, solubilizers, vitamins, pigments and fragrances, and conventional adjuvants, and carriers are additionally added. can be added.
본 발명의 화장료 조성물은 당업계에서 통상적으로 제조되는 어떠한 제형으로도 제조될 수 있으며, 예를 들어, 용액, 현탁액, 유탁액, 페이스트, 겔, 크림, 로션, 파우더, 비누, 계면활성제-함유 클린싱, 오일, 분말 파운데이션, 유탁액 파운데이션, 왁스 파운데이션 및 스프레이 등으로 제형화될 수 있으나, 이에 한정되는 것은 아니다. 보다 상세하게는, 비누, 영양 크림, 수렴 화장수, 유연 화장수, 로션, 에센스, 영양젤 또는 마사지 크림의 제형으로 제조될 수 있다.The cosmetic composition of the present invention may be prepared in any formulation conventionally prepared in the art, for example, solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing , oil, powder foundation, emulsion foundation, wax foundation, spray, etc., but is not limited thereto. More specifically, it may be prepared in the form of soap, nourishing cream, astringent lotion, softening lotion, lotion, essence, nutrition gel or massage cream.
이와 같이, 본 발명은 한방 발효물을 포함하는 피부 개선을 위한 조성물에 관한 것으로, 보다 구체적으로는 행인, 양제근, 접골목, 천문동, 감초 , 석죽 , 산자고 추출 발효물 포함하는 피부 기능 개선을 위한 화장료 조성물을 제공한다.As described above, the present invention relates to a composition for improving skin comprising a fermented oriental medicine, and more specifically, a cosmetic for improving skin function, including a fermented product extracted from passers-by, Yangjegeun, osteophyte, Cheonmun-dong, licorice, Seokjuk, and Sanjago. A composition is provided.
본 발명은 피부 기능 개선효과 및 피부노화 방지 효과가 우수하고 안전성 및 안정성이 높아 피부 부작용이 없는 천연유래 화장품 소재를 개발하고자 노력하여 천연 한방소재를 이용하여 아토피 등 각종 피부질환에 유용한 효과를 제공한다.The present invention strives to develop a natural cosmetic material that has excellent skin function improvement effect and skin aging prevention effect, and has high safety and stability, without skin side effects, and provides useful effects for various skin diseases such as atopic dermatitis using natural oriental medicinal materials. .
본 명세서에 첨부되는 다음의 도면들은 본 발명의 바람직한 실시예를 예시하는 것이며, 전술한 발명의 내용과 함께 본 발명의 기술사상을 더욱 이해시키는 역할을 하는 것이므로, 본 발명은 그러한 도면에 기재된 사항에만 한정되어 해석되어서는 아니 된다.
도 1은 본 발명에 따른 혼합 추출물의 사진이다.
도 2는 본 발명에 따른 혼합추출물의 발효를 중지할 시점을 보여주는 발효꽃상태 사진이다.
도 3은 내지 도 4는 본 발명에 따른 발효추출물을 포함하는 비누 사용시 피부개선효과를 보여 주는 사진이다.
도 5는 본 발명에 따른 발효추출물을 포함하는 비누 사진이다.The following drawings attached to this specification illustrate preferred embodiments of the present invention, and serve to further understand the technical spirit of the present invention together with the above-described content of the present invention, so the present invention is limited to the matters described in those drawings It should not be construed as being limited.
1 is a photograph of a mixed extract according to the present invention.
Figure 2 is a fermented flower state photograph showing the time to stop the fermentation of the mixed extract according to the present invention.
3 to 4 are photographs showing the skin improvement effect when using the soap containing the ferment extract according to the present invention.
5 is a photograph of a soap containing a fermentation extract according to the present invention.
이하, 본 발명의 이해를 돕기 위하여 실시예 등을 들어 상세하게 설명하기로 한다. 그러나, 본 발명에 따른 실시예들은 여러 가지 다른 형태로 변형될 수 있으며, 본 발명의 범위가 하기 실시예들에 한정되는 것으로 해석되어서는 안 된다. 본 발명의 실시예들은 당업계에서 평균적인 지식을 가진 자에게 본 발명을 보다 완전하게 설명하기 위해 제공되는 것이다. Hereinafter, examples and the like will be described in detail to help the understanding of the present invention. However, the embodiments according to the present invention may be modified in various other forms, and the scope of the present invention should not be construed as being limited to the following examples. The embodiments of the present invention are provided to more completely explain the present invention to those of ordinary skill in the art.
<실시예 1> 행인, 양제근, 접골목, 천문동, 감초 , 석죽 , 산자고의 발효추출물을 포함하는 조성물의 제조<Example 1> Preparation of a composition comprising a fermented extract of passers-by, yangjegeun, zygomok, Cheonmundong, licorice, Seokjuk, and Sanjago
건조 분말화한 원재료를 행인 20중량%, 양제근 15중량%, 접골목 15중량%, 천문동 20중량%, 감초 10중량% , 석죽 3중량% , 산자고 5중량%의 비율로 혼합하여 1차 열수추출을 진행하며, 1차 추출 후 10일 정도 음지에 숙성시키면 자연발생 발효꽃이 피기시작하는데 발효꽃이 전체 원액의 1/3정도 발생했을 때, 2년~5년 숙성된 추출원액을 전체 추출량 대비 3%를 추가로 투입해 혼합하여 2차 열수추출과정을 거쳐 15일 정도 저온숙성하고 상온에 보관한다.Primary hot water extraction by mixing dry powdered raw materials in the proportions of 20% by weight of passerine, 15% by weight of yangjeun, 15% by weight of bone marrow, 20% by weight of Cheonmundong, 10% by weight of licorice, 3% by weight of stone porridge, and 5% by weight of sanjago After the first extraction, if it is aged in the shade for about 10 days, naturally occurring fermented flowers begin to bloom. When the fermented flowers are about 1/3 of the total undiluted solution, the extracted undiluted solution aged 2 to 5 years is compared to the total extraction amount. Add an additional 3%, mix, undergo a secondary hot water extraction process, age at low temperature for about 15 days, and store at room temperature.
<실시예 2> 행인, 양제근, 접골목, 천문동, 감초 , 석죽 , 산자고의 유산균 발효추출물을 포함하는 조성물의 제조<Example 2> Preparation of a composition comprising the lactic acid bacteria fermented extract of passers-by, Yangjegeun, zygomok, Cheonmundong, licorice, Seokjuk, and Sanjago
상기 실시예 1에서 혼합추출물에 락토바실러스 플란타룸(L. plantarum) 균을 5 중량%의 양으로 접종하여 12시간 동안 배양하여 추출 발효물을 제조하였다. In Example 1, the mixed extract was inoculated with Lactobacillus plantarum in an amount of 5% by weight and cultured for 12 hours to prepare an extract ferment.
<시험예 1> 인체 피부에 대한 안전성 확인 <Test Example 1> Confirmation of safety on human skin
본 발명 추출 발효물이 인체피부에 안전한지 확인하기 위하여, 피부 안전성 검증 실험을 수행하였다. 이를 위해 피부누적 자극시험을 실시하였는 바 건강한 30명의 성인을 대상으로 윗팔뚝 부위에 격일로 총 9회의 24시간 누적 첩포를 시행하여 추출 발효물이 피부에 자극을 주는지 여부를 측정하였다. 첩포 방법은 핀 챔버(Finn chamber, Epitest Ltd, 핀란드)를 이용하였다. 챔버에 상기 각 피부 외용제를 15 ㎕씩 적하한 후 첩포를 실시하였다. In order to confirm whether the extract fermented product of the present invention is safe for human skin, a skin safety verification experiment was performed. To this end, a cumulative skin irritation test was conducted. For 30 healthy adults, a total of 9 24-hour cumulative patches were applied on the upper forearm every other day to determine whether the extract fermented product stimulates the skin. The patching method used a pin chamber (Finn chamber, Epitest Ltd, Finland). After 15 µl of each of the above skin external preparations was dripped into the chamber, patching was performed.
반응도에서 ±는 1점, +는 2점 및 ++는 4점의 점수를 부여하며, 평균반응도가 3 미만일 때 안전한 조성물로 판정된다.In the reactivity, ± is given a score of 1 point, + is given a score of 2, and ++ is given a score of 4, and when the average reactivity is less than 3, it is judged as a safe composition.
반응도Average
reactivity
(스쿠알렌)control
(Squalene)
[시험군 1]extract
[Test group 1]
[시험군 2]extract fermented product
[Test group 2]
상기 표 5에서 시험군 1 및 2 모두 ±, + 및 ++에 해당하는 사람의 수가 각각 0명, 0명 및 1명이고, 평균 반응도는 각각 0.00, 0.00이었다. 그러므로 평균반응도가 3 이하의 반응도를 나타내므로, 본 발명에 따른 추출 발효물은 뚜렷한 누적자극 양상을 나타내지 않는 인체 피부에 안전한 물질로 판정되었다.In Table 5, in both test groups 1 and 2, the number of persons corresponding to ±, + and ++ was 0, 0, and 1, respectively, and the average reactivity was 0.00 and 0.00, respectively. Therefore, since the average reactivity shows a reactivity of 3 or less, the extract fermented product according to the present invention was determined to be a safe material for human skin that does not show a distinct cumulative stimulation pattern.
<시험예 2> 화장료의 피부개선 효과 측정<Test Example 2> Measurement of skin improvement effect of cosmetics
상기 실시예 1 및 2에서 제조된 발효 추출물을 포함하여 통상의 방법으로 비누를 제조하여 사용후 피부탄력 개선효과 관찰하였다.Including the ferment extract prepared in Examples 1 and 2, a soap was prepared in a conventional manner, and the skin elasticity improvement effect was observed after use.
피부탄력의 측정은 온도 24 내지 26℃, 습도 38 내지 40%로 일정하게 유지되는 조건에서 건강한 여성 30명(25 내지 35세)을 대상으로 실시예 1 및 실시예 2의 비누와 시판 비교예의 비누를 각각 피검자의 얼굴에 칠하고 3분간 방치한 후 물로 닦아내는 시술로 1일 2회씩 7주 동안 사용하게 한 후, Cutometer SEM 474(Courage + Khazaka, Cologne, 독일)를 이용하여 측정함으로써 수행하였으며, 판정기준은 피부탄력이 없는 경우를 0, 많은 경우를 5로 하여 상대적인 값을 비교하였다. 시험결과는 하기 표 1에 나타내었다. The measurement of skin elasticity was carried out with the soaps of Examples 1 and 2 and the commercial soaps of Examples 1 and 2 targeting 30 healthy women (25 to 35 years of age) under conditions maintained constant at a temperature of 24 to 26° C. and a humidity of 38 to 40%. was applied to the subject's face, left for 3 minutes, and then washed with water twice a day for 7 weeks, followed by measurement using a Cutometer SEM 474 (Courage + Khazaka, Cologne, Germany). As for the criterion, relative values were compared by setting 0 for no skin elasticity and 5 for many cases. The test results are shown in Table 1 below.
상기 표 3에서 보듯이, 본 발명의 제조예 1 및 2의 비누가 비교 제조예의 시중 구입 비누에 비해 피부탄력 개선 효과가 훨씬 우수하여, 비누를 칠하고 3분간 방치한 후 물로 세닦아내는 단순한 시술로 우수한 피부탄력도를 가짐을 확인할 수 있었다.As shown in Table 3, the soaps of Preparation Examples 1 and 2 of the present invention have much superior skin elasticity improvement effect compared to the commercially available soaps of Comparative Preparation Examples, and a simple procedure of rinsing with water after applying the soap and leaving it for 3 minutes It was confirmed that it had excellent skin elasticity.
<시험예 3> 화장료의 피부질환 개선 효과 측정<Test Example 3> Measurement of the skin disease improvement effect of cosmetics
실시예1에 의해 제조된 비누를 5명 각각 피검자의 아토피성 환부에 칠하고 3분간 방치한 후 물로 닦아내는 시술로 1일 2회씩 7주 동안 사용하게 한 후 환후를 관찰하였는바, 도 3에는 보는바와같이 완치되었음을 확인하였다. The soap prepared in Example 1 was painted on the atopic affected area of the subject by 5 people, left for 3 minutes, and then used twice a day for 7 weeks by wiping off with water, and then the conditions were observed. As you can see, it was confirmed that it was completed.
하기에는 본 발명의 조성물을 위한 제제예를 예시한다.Examples of formulations for the composition of the present invention are exemplified below.
<제제예 1> 화장료 제제<Formulation Example 1> Cosmetic formulation
1-1. 마사지 크림의 제조1-1. manufacture of massage cream
하기 표 3에 나타낸 바와 같은 조성으로 추출 발효물을 유효성분으로 포함하는 마사지 크림을 통상의 방법에 따라 제조하였다. A massage cream containing an extract fermented product as an active ingredient with a composition as shown in Table 3 was prepared according to a conventional method.
1-2. 팩의 제조1-2. manufacture of packs
하기 표 4에 나타낸 바와 같은 조성으로 추출 발효물을 유효성분으로 포함하는 팩을 통상의 방법에 따라 제조하였다. A pack containing an extract fermented product as an active ingredient with a composition as shown in Table 4 was prepared according to a conventional method.
이상으로 본 발명의 특정한 부분을 상세히 기술하였는바, 당업계의 통상의 지식을 가진 자에게 있어서 이러한 구체적인 기술은 단지 바람직한 구현예일 뿐이며, 이에 본 발명의 범위가 제한되는 것이 아닌 점은 명백하다. 따라서, 본 발명의 실질적인 범위는 첨부된 청구항과 그의 등가물에 의하여 정의된다고 할 것이다.As described above in detail a specific part of the present invention, for those of ordinary skill in the art, these specific descriptions are only preferred embodiments, and it is clear that the scope of the present invention is not limited thereto. Accordingly, the substantial scope of the present invention will be defined by the appended claims and their equivalents.
Claims (5)
상기 혼합 추출물의 발효추출물은 원재료 추출효능을 최대한 끌어올리기 위해 1차 열수추출을 진행하며, 1차 추출 후 10일 정도 음지에 숙성시키면서 자연발생 발효꽃이 전체 추출액의 1/3 정도 발생했을 때, 2년~5년 숙성된 추출원액을 전체 추출량 대비 3%를 추가로 투입해 혼합하여 2차 열수추출과정을 거쳐 15일 정도 저온숙성하며,
상기 저온숙성된 혼합 추출물에 유산균을 접종하여 10 내지 20시간 동안 배양하여 발효된 것임을 특징으로 하는 피부 기능 개선을 위한 화장료 조성물.Fermentation of a mixed extract extracted with hot water by mixing dry powdered passersby 20% by weight, Yangjegeun 15% by weight, osteophyte 15% by weight, Cheonmundong 20% by weight, licorice 10% by weight, Seokjuk 3% by weight, and Sanjago 5% by weight including extracts,
The fermented extract of the mixed extract is subjected to primary hot water extraction in order to maximize the extraction efficiency of the raw material, and after the primary extraction is aged in the shade for about 10 days, naturally occurring fermented flowers are generated about 1/3 of the total extract, The extracted undiluted solution aged for 2 to 5 years is mixed with an additional 3% of the total amount of extraction, followed by a secondary hot water extraction process and aged at low temperature for 15 days.
A cosmetic composition for improving skin function, characterized in that it is fermented by inoculating the low-temperature-aged mixed extract with lactic acid bacteria and culturing for 10 to 20 hours.
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KR101456052B1 (en) * | 2007-04-20 | 2014-11-03 | 주식회사 엘지생활건강 | Cosmetic composition for improving wrinkles |
KR100958496B1 (en) * | 2008-02-25 | 2010-05-17 | (주)에이티 랩 | Composition with hair loss prevention and hair growth function using natural derived resources |
KR101373636B1 (en) * | 2011-12-23 | 2014-03-13 | (주) 젠셀 | Composition for improving condition of skin and scalp containing fermented extracts of herb mixture |
KR101918673B1 (en) * | 2017-04-17 | 2018-11-14 | 주식회사 콧데 | A novel marine-derived bacterium, and cosmetic compositions using the same |
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