CN104873433A - Moxa skin cream and preparing method thereof - Google Patents
Moxa skin cream and preparing method thereof Download PDFInfo
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Abstract
The invention discloses moxa skin cream and a preparing method thereof. The moxa skin cream comprises alcohol extract, water extract and other extracts; the alcohol extract is extracted from sun-dried wild moxa aged for three years, grassleaf sweelflag rhizome, skullcap root and light yellow Sophora root via ethyl alcohol and propylene glycol; the water extract is extracted from herbs, such as licorice root, wild soybean, oatmeal kernel, Azadirachta indica leaf, marshmallow root and cornflower, via water extraction; the other extracts are extracted from probiotic fermentation liquors of moxa and herbs. The effective ingredients extracted from the moxa and herbs by different extracting processes are evenly and reasonably combined with cetanol-octadecanol mixture, jojoba oil, camellia seed oil, Perilla seed soil and the like so as to obtain the moxa skin cream good in protective capacity.
Description
Technical field
The present invention relates to a kind of Folium Artemisiae Argyi protective skin cream and preparation method thereof, belong to cosmetics and skincare product technical field.
Background technology
The fast development of beauty industry, brings Gospel to the vast personage that likes to be beautiful.But due to Chaoyang industry development early stage lack of standard and eager for instant success and quick profits property, cause some products of inferior quality, or even have the quick-acting products of side effect to come into the market to skin, cause dark or shallow injury to some personages that like to be beautiful.Moreover, the food pollution of society, the environmental problems such as air pollution also in various degree affect the healthy and beautiful of the mankind, make the no matter interior diet of people or cosmetics for external use, have the trend that " toxin " increases and accumulate.Therefore only from the aspect of external cosmetics and skincare product, developing the pure natural skin care item with toxin expelling maintenance action further will be the current and following development trend.
Folium Artemisiae Argyi, has another name called " doctor's grass ".That people are used for the Chinese herbal medicine of " keeping away evil to get rid of evils " since ancient times.Modern science proves: containing the multiple efficacies composition such as volatile oil, flavone, eudesmane, triterpenes and Protein microassay element in Folium Artemisiae Argyi, no matter is for oral administration or external all can produce the maintenance action of " strengthening vital QI to eliminate pathogenic factors " to human body.But Folium Artemisiae Argyi itself has pros and cons duality, though there is the positive acting promoting resistance of human body and immunity, also can causes side effect to human body after excessive edible or a large amount of external, even damage.The feature of this pros and cons dual character make this effect of Folium Artemisiae Argyi well " doctor's grass " in the daily life of modern, the people that should not be lived by fast pace grasp and use.And apply to the patent documentation of cosmetics and skincare product especially in facial cream class skin care item and also do not have.Therefore how to make full use of Folium Artemisiae Argyi advantage, keep away its shortcoming, and in the skin care item facial cream product that can commonly use to people of balanced collocation, reasonable combination, will merit attention and further investigate.
Summary of the invention
Blank present situation is still occupied for the application of current Folium Artemisiae Argyi in skin protection facial cream, the invention provides a kind of Folium Artemisiae Argyi protective skin cream and preparation method thereof, the employing " 3 years Chen Ai " that the present invention is bold, and coordinate Folium Artemisiae Argyi, wild soybean seed, Rhizoma Acori Graminei, Neem leaves, scutellariae,radix, Sakura leaf, root of Paeonia suffruticosa Ardr., oat kernel, althaea root, leaf of Herb Gynostemmae Pentaphylli, very thin Herba Erodii, Centaurea cyanus, Herba Houttuyniae, Herba Taraxaci, Rhizoma Saururi (Herba Saururi), Herba Portulacae, the Chinese medicines such as Radix Sophorae Flavescentis, first carry out ethanol, propylene glycol extraction goes out concentrated solution, carry out water extraction again and extract Aqueous extracts, and then carry out probiotics fermention process, finally by alcohol extract, Aqueous extracts and fermentation liquid three share.This new formula, new technology can utilize Folium Artemisiae Argyi and kinds of traditional Chinese medicines effect in toxin expelling skin protection preferably, and greatly reduce the drawback of Folium Artemisiae Argyi itself, and the Folium Artemisiae Argyi protective skin cream product that this is invented can reach good skin effect and apply effect.
For achieving the above object, the present invention is by the following technical solutions:
A kind of Folium Artemisiae Argyi protective skin cream, be made up of the component of following weight portion:
(1) oil phase component: described oil phase component is made up of the component of following weight parts: 16 mixed alcohols 1 ~ 1.5 part, 16 stearyl alcohol and 16 octadecyl glucosides 2 ~ 4 parts, tristerin and PEG-100 stearate 2 ~ 3 parts, Jojoba oil 2 ~ 4 parts, isomery hexadecane hydrocarbon 2 ~ 4 parts, seed of Flos Camelliae Japonicae oil 1 ~ 3 part, Oleum Perillae 1 ~ 2 part, isopropyl myristate 1 ~ 3 part, dimethicone 2 ~ 4 parts, methyl hydroxybenzoate 0.2 ~ 0.3 part, propylparaben 0.1 ~ 0.15 part, ditertbutylparacresol 0.03 ~ 0.05 part;
(2) water phase components: described water phase components is made up of the component of following weight parts: glycerol 5 ~ 8 parts, modified corn syrup (commodity English name: MOISYRUP, by Shanghai, Shun Tuo scientific & trading Co., Ltd. provides) 2 ~ 4 parts, trehalose 1 ~ 2 part, trimethyl glycine 2 ~ 4 parts, self-control C extracting solution 40 ~ 60 parts, described self-control C extracting solution is made up of the raw material of following weight portion: 5 ~ 10 parts, Radix Glycyrrhizae, wild soybean seed 3 ~ 5 parts, oat kernel 4 ~ 5 parts, root of Paeonia suffruticosa Ardr., althaea root, each 3 ~ 4 parts of Herba Houttuyniae, Neem leaves, Sakura leaf, leaf of Herb Gynostemmae Pentaphylli, very thin Herba Erodii, Centaurea cyanus, Herba Taraxaci, Rhizoma Saururi (Herba Saururi), each 1 ~ 3 part of Herba Portulacae,
(3) extracting solution component: self-control A extracting solution 2 ~ 4 parts, self-control D extracting solution 5 ~ 10 parts;
(4) co-emulsifier component: hydroxy acrylic acid brine and sodium acryloyldimethyl taurate copolymers 0.5 ~ 1 part;
(5) antiseptic: mixture 0.1-0.15 part of MIT and 3-iodo-2-propynyl butyl carbamate;
(6) essence: floral perfume 0.01-0.02 part.
The preparation method of Folium Artemisiae Argyi protective skin cream, comprises the steps:
(1) preparation of oil phase component: 16 mixed alcohols of formula ratio, 16 stearyl alcohol and 16 octadecyl glucosides, tristerin and PEG-100 stearate, Jojoba oil, isomery hexadecane hydrocarbon, seed of Flos Camelliae Japonicae oil, Oleum Perillae, Semen Myristicae propyl ester, dimethicone, methyl hydroxybenzoate, propylparaben, ditertbutylparacresol are added in the rustless steel still of band stirring after taking in proportion, under the stirring of rotating speed 20 ~ 30 revs/min, heating for dissolving is complete, and constant temperature disinfection 20 minutes is stand-by at 80 ~ 85 DEG C;
(2) preparation of water phase components: the glycerol of formula ratio, modified corn syrup, trehalose, trimethyl glycine, self-control C extracting solution are taken rear elder generation heating for dissolving in rustless steel still in proportion, then be extracted in rustless steel homogenizing still, under the stirring of 20 ~ 30 revs/min, continue to be heated to 80 ~ 85 DEG C, and constant temperature disinfection 20 minutes is stand-by;
(3) by oil phase slowly suction aqueous phase, and carry out scraping wall stirring, stir 2-3 minute scraping under wall rotating speed is 40-50 rev/min, start high speed homogenization device homogenizing 3-5 minute under the high speed of 3000-5000 rev/min, wall rotating speed will be scraped afterwards and drop to 30-40 rev/min, and be cooled to 45-50 DEG C under this rotating speed;
(4) then add the self-control A extracting solution of formula ratio and make D extracting solution and co-emulsifier by oneself, 20-30 minute is stirred under the rotating speed of 20-30 rev/min, continue afterwards to cool to 40 DEG C, add antiseptic and the essence of formula ratio, continue to stir 15-20 minute under same rotating speed, get final product discharging, obtained Folium Artemisiae Argyi protective skin cream.
The preparation method of described self-control A extracting solution comprises the following steps:
(1) Mao Pu, scutellariae,radix, Radix Sophorae Flavescentis coarse powder are broken into≤segment of 3cm or the small pieces of diameter≤3cm, take Folium Artemisiae Argyi 5 ~ 8 parts, Rhizoma Acori Graminei 3 ~ 6 parts, scutellariae,radix, each 4 ~ 6 parts of Radix Sophorae Flavescentis, propylene glycol 10 ~ 15 parts, volumetric concentration is the alcoholic solution 600 ~ 700 parts of 60% ~ 80%, at 70 ~ 90 DEG C, reflux alcohol extraction 1 ~ 3 hour, with obtain respectively after 600 order filter-cloth filterings filtering residue 1. with alcohol extract 1.;
(2) filtering residue obtained in described step (1) 1. in add volumetric concentration be 60% ~ 80% alcoholic solution 500 ~ 600 parts, propylene glycol 5 ~ 10 parts, at 70 ~ 90 DEG C, reflux alcohol extraction 1 ~ 3 hour, with obtain after 600 order filter-cloth filterings filtering residue 2. with alcohol extract 2.;
(3) by described alcohol extract 1., 2. alcohol extract merge post-heating concentration and recovery ethanol, when liquid to be mixed is concentrated to 30 ~ 50 parts, must make Folium Artemisiae Argyi, Rhizoma Acori Graminei, scutellariae,radix, the ethanol of Radix Sophorae Flavescentis and the concentrated solution of propylene glycol extraction liquid by oneself, called after self-control A extracting solution;
(4) filtering residue obtained in described step (2) 2. in add 300 ~ 400 parts of deionized waters, be heated to boiling, and remain on slight boiling condition and boil 0.8 ~ 1.0 hour, then with 600 order filter-cloth filterings namely obtain filtering residue 3. with Aqueous extracts 1.;
(5) step (4) gained filtering residue 3. in add the deionized water of 200 ~ 300 parts again, be heated to boiling, and boil 0.5 ~ 0.8 hour at slight boiling condition, then with 600 order filter-cloth filterings namely obtain filtering residue 4. and Aqueous extracts 2.;
(6) by Aqueous extracts 1., Aqueous extracts namely obtain after 2. merging self-control Folium Artemisiae Argyi, Rhizoma Acori Graminei, scutellariae,radix, Radix Sophorae Flavescentis Aqueous extracts, control water evaporation quantity, make the Aqueous extracts total amount finally concentrating molding be add total Water 1/3, B extracting solution must be made by oneself.
The preparation method of described self-control C extracting solution comprises the following steps:
(1) 5 ~ 10 parts, Radix Glycyrrhizae is taken, wild soybean seed 3 ~ 5 parts, oat kernel 4 ~ 5 parts, each 3 ~ 4 parts of root of Paeonia suffruticosa Ardr., althaea root, Herba Houttuyniae, Neem leaves, Sakura leaf, leaf of Herb Gynostemmae Pentaphylli, very thin Herba Erodii, Centaurea cyanus, Herba Taraxaci, Rhizoma Saururi (Herba Saururi), each 1 ~ 3 part of Herba Portulacae, will join in enamel Chinese medicine extracting tank after partial block in these Chinese medicines, the segment of coarse crushing one-tenth≤3cm that leaf is larger or the small pieces of diameter≤3cm;
(2) when first time boils, taking deionized water 600 ~ 700 parts adds in enamel Chinese medicine extracting tank, soak 30 minutes post-heating to boiling, and remain on slight boiling condition and boil 0.8 ~ 1.0 hour, then with 600 order filter-cloth filterings namely obtain water extraction filtering residue 1. with Aqueous extracts 1.;
(3) the obtained water extraction filtering residue of step (2) 1. in add the deionized water of 500 ~ 600 parts again, be heated to boiling, and remain on slight boiling condition and boil 0.6 ~ 0.8 hour, then with 600 order filter-cloth filterings namely obtain water extraction filtering residue 2. with Aqueous extracts 2.;
(4) by above-mentioned Aqueous extracts 1., namely 2. Aqueous extracts obtain self-control Chinese traditional medicine water extract after mix homogeneously, control water evaporates amount, make the Aqueous extracts total amount finally concentrating molding be the half adding the water yield, C extracting solution must be made by oneself.
The preparation method of described self-control D extracting solution comprises the following steps: (1) described water extraction filtering residue 2. in add sucrose 5 ~ 8 parts, glucose 3 ~ 5 parts, dipotassium hydrogen phosphate 0.3 ~ 0.5 part, 0.1 ~ 0.2 part, sodium chloride, pure water 300 ~ 400 parts, be heated to boiling, constant temperature disinfection 20 minutes, then 30 ~ 35 DEG C are cooled to, add 50 ~ 100 parts of self-control C extracting solution, (2) (strain is purchased from Chinese industrial Culture Collection then to press the Aureobasidium pullulans strain after the inoculum concentration access amplification culture of 2 ~ 3% of fermentation bed material total amount, bacterium numbering: CICC41349), fermentation culture is after 1 ~ 3 day, (strain is purchased from Chinese industrial Culture Collection to add the Pichia sp. strain of 1 ~ 2% of fermentation bed material total amount again, bacterium numbering: CICC33024) and fermentation bed material total amount 1 ~ 3% Lactobacillus plantarum strain ((strain is purchased from Chinese industrial Culture Collection, bacterium numbering: CICC6240)), continue fermentation culture 1 ~ 3 day, and then system temperature is dropped to 28 ~ 30 DEG C, continue fermentation and add self-control B extracting solution and filtering residue after 1 ~ 2 day 4., continue fermentation 2 ~ 3 days, get fermentation liquid inspection thalline sum, if be greater than 500CFU/ML, continue fermentation 1 ~ 5 day or use ozone sterilization system for handling, until viable bacteria body approach exhaustion in system, until thalline sum≤500CFU/ML in system, then fermentation liquid is crossed 600 order filter clothes to leach, (3) then below 50 DEG C vacuum concentration to 1/2 of total fermentation filtrate volume, the concentrated solution of obtained fermented extracted liquid, namely D extracting solution is made by oneself.
The selection of Folium Artemisiae Argyi and early-stage preparations in the present invention: containing more volatile oil and taste component in fresh Folium Artemisiae Argyi, if extracting directly is applied in skin care item, not only taste is comparatively large, also skin can be caused uncomfortable because the dryness in Folium Artemisiae Argyi is too large.Therefore wild Folium Artemisiae Argyi is gathered afterwash by the present invention, first make dry product by Exposure to Sunlight repeatedly, then be placed on shady and cool dry, draughty indoor lucifuge and store 3 years, make Folium Artemisiae Argyi slowly aging, leave volatile oil too much in Folium Artemisiae Argyi, and alleviate its dryness, and then coarse powder is broken into≤3CM segment use.
Compared with prior art, beneficial effect of the present invention is: both after the pretreatment of Folium Artemisiae Argyi sets about wild Folium Artemisiae Argyi to dry, carried out ageing in 3 years, adopt water extraction from technique again, the new and innovative ways that probiotics fermention combines mentioned by alcohol, can make that Folium Artemisiae Argyi is this seldom to be applied in skin-protection product by " doctor grass " of public use is relatively mild after removing some anaphylactogens of dryness, reduction and conversion.Both retained and added Folium Artemisiae Argyi itself " keeping away evil to get rid of evils ", and promoted the advantage of resistance of human body and immunity, the gas of irritability excessively strong for Folium Artemisiae Argyi can be reduced again, side effect greatly reduces, meanwhile, coordinating of the compositions such as Folium Artemisiae Argyi and plurality of Chinese, the effect of also can play balanced collocation, having complementary advantages.Therefore the present invention has not only filled up the blank of Folium Artemisiae Argyi tea in skin care item application, also for the vast personage of liking to be beautiful provides the skin protection non-defective unit of a novelty, this is air, environment etc. pollute day by day serious modern society, a large Gospel of people beyond doubt instantly.
Detailed description of the invention
embodiment 1
The preparation method of making A extracting solution in the present embodiment by oneself comprises the following steps:
(1) Mao Pu, scutellariae,radix, Radix Sophorae Flavescentis coarse powder are broken into≤segment of 3cm or the small pieces of diameter≤3cm, take Folium Artemisiae Argyi 8 parts, Rhizoma Acori Graminei 4 parts, scutellariae,radix, each 4 parts of Radix Sophorae Flavescentis, propylene glycol 15 parts, volumetric concentration is the alcoholic solution 700 parts of 80%, at 90 DEG C, reflux alcohol extraction 3 hours, with obtain respectively after 600 order filter-cloth filterings filtering residue 1. with alcohol extract 1.;
(2) filtering residue obtained in described step (1) 1. in add volumetric concentration be 80% alcoholic solution 600 parts, propylene glycol 10 parts, at 90 DEG C, reflux alcohol extraction 1 ~ 3 hour, with obtain after 600 order filter-cloth filterings filtering residue 2. with alcohol extract 2.;
(3) by described alcohol extract 1., 2. alcohol extract merge post-heating concentration and recovery ethanol, when liquid to be mixed is concentrated to 30 parts, must make Folium Artemisiae Argyi, Rhizoma Acori Graminei, scutellariae,radix, the ethanol of Radix Sophorae Flavescentis and the concentrated solution of propylene glycol extraction liquid by oneself, called after self-control A extracting solution;
(4) filtering residue obtained in described step (2) 2. in add 400 parts of deionized waters, be heated to boiling, and remain on slight boiling condition and boil 1.0 hours, then with 600 order filter-cloth filterings namely obtain filtering residue 3. with Aqueous extracts 1.;
(5) step (4) gained filtering residue 3. in add the deionized water of 200 parts again, be heated to boiling, and boil 0.6 hour at slight boiling condition, then with 600 order filter-cloth filterings namely obtain filtering residue 4. and Aqueous extracts 2.;
(6) by Aqueous extracts 1., Aqueous extracts namely obtain after 2. merging self-control Folium Artemisiae Argyi, Rhizoma Acori Graminei, scutellariae,radix, Radix Sophorae Flavescentis Aqueous extracts, control water evaporation quantity, make the Aqueous extracts total amount finally concentrating molding be add total Water 1/3, B extracting solution must be made by oneself.
The preparation method of making C extracting solution in the present embodiment by oneself comprises the following steps:
(1) 6 parts, Radix Glycyrrhizae is taken, wild soybean seed 3 parts, oat kernel 5 parts, each 4 parts of root of Paeonia suffruticosa Ardr., althaea root, Herba Houttuyniae, Neem leaves, Sakura leaf, leaf of Herb Gynostemmae Pentaphylli, very thin Herba Erodii, Centaurea cyanus, Herba Taraxaci, Rhizoma Saururi (Herba Saururi), each 2 parts of Herba Portulacae, will join in enamel Chinese medicine extracting tank after partial block in these Chinese medicines, the segment of coarse crushing one-tenth≤3cm that leaf is larger or the small pieces of diameter≤3cm;
(2) first time is when boiling, and takes deionized water 600 parts and adds in enamel Chinese medicine extracting tank, soaks 30 minutes post-heating to seething with excitement, and remains on slight boiling condition and boil 0.8 hour, then with 600 order filter-cloth filterings namely obtain water extraction filtering residue 1. with Aqueous extracts 1.;
(3) the obtained water extraction filtering residue of step (2) 1. in add the deionized water of 600 parts again, be heated to boiling, and remain on slight boiling condition and boil 0.8 hour, then with 600 order filter-cloth filterings namely obtain water extraction filtering residue 2. with Aqueous extracts 2.;
(4) by above-mentioned Aqueous extracts 1., namely 2. Aqueous extracts obtain self-control Chinese traditional medicine water extract after mix homogeneously, control water evaporates amount, make the Aqueous extracts total amount finally concentrating molding be the half adding the water yield, C extracting solution must be made by oneself.
The preparation method of making D extracting solution in the present embodiment by oneself comprises the following steps: (1) described water extraction filtering residue 2. in add sucrose 7 parts, glucose 3 parts, dipotassium hydrogen phosphate 0.5 part, 0.2 part, sodium chloride, pure water 400 parts, be heated to boiling, constant temperature disinfection 20 minutes, then 35 DEG C are cooled to, add 80 parts of self-control C extracting solution, (2) (strain is purchased from Chinese industrial Culture Collection then to press the Aureobasidium pullulans strain after the inoculum concentration access amplification culture of 3% of fermentation bed material total amount, bacterium numbering: CICC41349), fermentation culture is after 2 days, (strain is purchased from Chinese industrial Culture Collection to add the Pichia sp. strain of 2% of fermentation bed material total amount again, bacterium numbering: CICC33024) and fermentation bed material total amount 3% Lactobacillus plantarum strain ((strain is purchased from Chinese industrial Culture Collection, bacterium numbering: CICC6240)), continue fermentation culture 3 days, and then system temperature is dropped to 30 DEG C, continue fermentation and add self-control B extracting solution and filtering residue after 2 days 4., continue fermentation 3 days, get fermentation liquid inspection thalline sum, if be greater than 500CFU/ML, continue fermentation 4 days or use ozone sterilization system for handling, until viable bacteria body approach exhaustion in system, until thalline sum≤500CFU/ML in system, then fermentation liquid is crossed 600 order filter clothes to leach, (3) then below 50 DEG C vacuum concentration to 1/2 of total fermentation filtrate volume, the concentrated solution of obtained fermented extracted liquid, namely D extracting solution is made by oneself.
The present embodiment Folium Artemisiae Argyi protective skin cream, substitutes the pure water component in Folium Artemisiae Argyi protective skin cream, is made up of the component of following weight portion with obtained C extracting solution:
(1) oil phase component: described oil phase component is made up of the component of following weight parts: 16 mixed alcohols 1 part, 16 stearyl alcohol and 16 octadecyl glucosides 3 parts, tristerin and PEG-100 stearate 3 parts, Jojoba oil 2 parts, isomery hexadecane hydrocarbon 3 parts, seed of Flos Camelliae Japonicae oil 2 parts, Oleum Perillae 1 part, isopropyl myristate 2 parts, dimethicone 3 parts, methyl hydroxybenzoate 0.2 part, propylparaben 0.15 part, ditertbutylparacresol 0.03 part;
(2) water phase components: described water phase components is made up of the component of following weight parts: glycerol 6 parts, 4 parts, modified corn syrup (commodity English name: MOISYRUP, Shun Tuo scientific & trading Co., Ltd. provides by Shanghai), trehalose 2 parts, trimethyl glycine 4 parts, self-control C extracting solution 52 parts;
(3) extracting solution component: self-control A extracting solution 3 parts, self-control D extracting solution 8 parts;
(4) co-emulsifier component: hydroxy acrylic acid brine and sodium acryloyldimethyl taurate copolymers 0.5 part;
(5) antiseptic: 0.1 part, the mixture of MIT and 3-iodo-2-propynyl butyl carbamate;
(6) essence: floral perfume 0.02 part.
The preparation method of the present embodiment Folium Artemisiae Argyi protective skin cream, comprises the steps:
(1) preparation of oil phase component: 16 mixed alcohols of formula ratio, 16 stearyl alcohol and 16 octadecyl glucosides, tristerin and PEG-100 stearate, Jojoba oil, isomery hexadecane hydrocarbon, seed of Flos Camelliae Japonicae oil, Oleum Perillae, Semen Myristicae propyl ester, dimethicone, methyl hydroxybenzoate, propylparaben, ditertbutylparacresol are added in the rustless steel still of band stirring after taking in proportion, under the stirring of rotating speed 30 revs/min, heating for dissolving is complete, and constant temperature disinfection 20 minutes is stand-by at 85 DEG C;
(2) preparation of water phase components: the glycerol of formula ratio, modified corn syrup, trehalose, trimethyl glycine, self-control C extracting solution are taken rear elder generation heating for dissolving in rustless steel still in proportion, then be extracted in rustless steel homogenizing still, under the stirring of 30 revs/min, continue to be heated to 85 DEG C, and constant temperature disinfection 20 minutes is stand-by;
(3) by oil phase slowly suction aqueous phase, and carry out scraping wall and stir, stir 3 minutes scraping under wall rotating speed is 50 revs/min, start high speed homogenization device homogenizing 5 minutes under the high speed of 4000 revs/min, wall rotating speed will be scraped afterwards and drop to 35 revs/min, and be cooled to 50 DEG C under this rotating speed;
(4) then add the self-control A extracting solution of formula ratio and make D extracting solution and co-emulsifier by oneself, stir 20 minutes under the rotating speed of 30 revs/min, continue afterwards to cool to 40 DEG C, add antiseptic and the essence of formula ratio, continue to stir 18 minutes under same rotating speed, get final product discharging, obtained Folium Artemisiae Argyi protective skin cream.
embodiment 2
The preparation method of making A extracting solution in the present embodiment by oneself comprises the following steps:
(1) Mao Pu, scutellariae,radix, Radix Sophorae Flavescentis coarse powder are broken into≤segment of 3cm or the small pieces of diameter≤3cm, take Folium Artemisiae Argyi 7 parts, Rhizoma Acori Graminei 4 parts, scutellariae,radix, each 5 parts of Radix Sophorae Flavescentis, propylene glycol 13 parts, volumetric concentration is the alcoholic solution 600 parts of 70%, at 85 DEG C, reflux alcohol extraction 2 hours, with obtain respectively after 600 order filter-cloth filterings filtering residue 1. with alcohol extract 1.;
(2) filtering residue obtained in described step (1) 1. in add volumetric concentration be 70% alcoholic solution 550 parts, propylene glycol 9 parts, at 80 DEG C, reflux alcohol extraction 2 hours, with obtain after 600 order filter-cloth filterings filtering residue 2. with alcohol extract 2.;
(3) by described alcohol extract 1., 2. alcohol extract merge post-heating concentration and recovery ethanol, when liquid to be mixed is concentrated to 45 parts, must make Folium Artemisiae Argyi, Rhizoma Acori Graminei, scutellariae,radix, the ethanol of Radix Sophorae Flavescentis and the concentrated solution of propylene glycol extraction liquid by oneself, called after self-control A extracting solution;
(4) filtering residue obtained in described step (2) 2. in add 350 parts of deionized waters, be heated to boiling, and remain on slight boiling condition and boil 0.8 hour, then with 600 order filter-cloth filterings namely obtain filtering residue 3. with Aqueous extracts 1.;
(5) step (4) gained filtering residue 3. in add the deionized water of 260 parts again, be heated to boiling, and boil 0.7 hour at slight boiling condition, then with 600 order filter-cloth filterings namely obtain filtering residue 4. and Aqueous extracts 2.;
(6) by Aqueous extracts 1., Aqueous extracts namely obtain after 2. merging self-control Folium Artemisiae Argyi, Rhizoma Acori Graminei, scutellariae,radix, Radix Sophorae Flavescentis Aqueous extracts, control water evaporation quantity, make the Aqueous extracts total amount finally concentrating molding be add total Water 1/3, B extracting solution must be made by oneself.
The preparation method of making C extracting solution in the present embodiment by oneself comprises the following steps:
(1) 9 parts, Radix Glycyrrhizae is taken, wild soybean seed 5 parts, oat kernel 4 parts, each 3 parts of root of Paeonia suffruticosa Ardr., althaea root, Herba Houttuyniae, Neem leaves, Sakura leaf, leaf of Herb Gynostemmae Pentaphylli, very thin Herba Erodii, Centaurea cyanus, Herba Taraxaci, Rhizoma Saururi (Herba Saururi), each 3 parts of Herba Portulacae, will join in enamel Chinese medicine extracting tank after partial block in these Chinese medicines, the segment of coarse crushing one-tenth≤3cm that leaf is larger or the small pieces of diameter≤3cm;
(2) first time is when boiling, and takes deionized water 600 parts and adds in enamel Chinese medicine extracting tank, soaks 30 minutes post-heating to seething with excitement, and remains on slight boiling condition and boil 1.0 hours, then with 600 order filter-cloth filterings namely obtain water extraction filtering residue 1. with Aqueous extracts 1.;
(3) the obtained water extraction filtering residue of step (2) 1. in add the deionized water of 600 parts again, be heated to boiling, and remain on slight boiling condition and boil 0.7 hour, then with 600 order filter-cloth filterings namely obtain water extraction filtering residue 2. with Aqueous extracts 2.;
(4) by above-mentioned Aqueous extracts 1., namely 2. Aqueous extracts obtain self-control Chinese traditional medicine water extract after mix homogeneously, control water evaporates amount, make the Aqueous extracts total amount finally concentrating molding be the half adding the water yield, C extracting solution must be made by oneself.
The preparation method of making D extracting solution in the present embodiment by oneself comprises the following steps: (1) described water extraction filtering residue 2. in add sucrose 8 parts, glucose 5 parts, dipotassium hydrogen phosphate 0.5 part, 0.2 part, sodium chloride, pure water 300 parts, be heated to boiling, constant temperature disinfection 20 minutes, then 30 DEG C are cooled to, add 60 parts of self-control C extracting solution, (2) (strain is purchased from Chinese industrial Culture Collection then to press the Aureobasidium pullulans strain after the inoculum concentration access amplification culture of 2% of fermentation bed material total amount, bacterium numbering: CICC41349), fermentation culture is after 3 days, (strain is purchased from Chinese industrial Culture Collection to add the Pichia sp. strain of 2% of fermentation bed material total amount again, bacterium numbering: CICC33024) and fermentation bed material total amount 2% Lactobacillus plantarum strain ((strain is purchased from Chinese industrial Culture Collection, bacterium numbering: CICC6240)), continue fermentation culture 2 days, and then system temperature is dropped to 29 DEG C, continue fermentation and add self-control B extracting solution and filtering residue after 1 day 4., continue fermentation 3 days, get fermentation liquid inspection thalline sum, if be greater than 500CFU/ML, continue fermentation 3 days or use ozone sterilization system for handling, until viable bacteria body approach exhaustion in system, until thalline sum≤500CFU/ML in system, then fermentation liquid is crossed 600 order filter clothes to leach, (3) then below 50 DEG C vacuum concentration to 1/2 of total fermentation filtrate volume, the concentrated solution of obtained fermented extracted liquid, namely D extracting solution is made by oneself.
The present embodiment Folium Artemisiae Argyi protective skin cream, substitutes the pure water component in Folium Artemisiae Argyi protective skin cream, is made up of the component of following weight portion with obtained C extracting solution:
(1) oil phase component: described oil phase component is made up of the component of following weight parts: 16 mixed alcohols 1.5 parts, 16 stearyl alcohol and 16 octadecyl glucosides 2 parts, tristerin and PEG-100 stearate 2 parts, Jojoba oil 4 parts, isomery hexadecane hydrocarbon 4 parts, seed of Flos Camelliae Japonicae oil 3 parts, Oleum Perillae 2 parts, isopropyl myristate 3 parts, dimethicone 4 parts, methyl hydroxybenzoate 0.3 part, propylparaben 0.15 part, ditertbutylparacresol 0.03 part;
(2) water phase components: described water phase components is made up of the component of following weight parts: glycerol 8 parts, 3 parts, modified corn syrup (commodity English name: MOISYRUP, Shun Tuo scientific & trading Co., Ltd. provides by Shanghai), trehalose 1 part, trimethyl glycine 3 parts, self-control C extracting solution 45 parts;
(3) extracting solution component: self-control A extracting solution 4 parts, self-control D extracting solution 9 parts;
(4) co-emulsifier component: hydroxy acrylic acid brine and sodium acryloyldimethyl taurate copolymers 0.9 part;
(5) antiseptic: 0.1 part, the mixture of MIT and 3-iodo-2-propynyl butyl carbamate;
(6) essence: floral perfume 0.02 part.
The preparation method of the present embodiment Folium Artemisiae Argyi protective skin cream, comprises the steps:
(1) preparation of oil phase component: 16 mixed alcohols of formula ratio, 16 stearyl alcohol and 16 octadecyl glucosides, tristerin and PEG-100 stearate, Jojoba oil, isomery hexadecane hydrocarbon, seed of Flos Camelliae Japonicae oil, Oleum Perillae, Semen Myristicae propyl ester, dimethicone, methyl hydroxybenzoate, propylparaben, ditertbutylparacresol are added in the rustless steel still of band stirring after taking in proportion, under the stirring of rotating speed 25 revs/min, heating for dissolving is complete, and constant temperature disinfection 20 minutes is stand-by at 80 DEG C;
(2) preparation of water phase components: the glycerol of formula ratio, modified corn syrup, trehalose, trimethyl glycine, self-control C extracting solution are taken rear elder generation heating for dissolving in rustless steel still in proportion, then be extracted in rustless steel homogenizing still, under the stirring of 25 revs/min, continue to be heated to 85 DEG C, and constant temperature disinfection 20 minutes is stand-by;
(3) by oil phase slowly suction aqueous phase, and carry out scraping wall and stir, stir 3 minutes scraping under wall rotating speed is 45 revs/min, start high speed homogenization device homogenizing 3 minutes under the high speed of 5000 revs/min, wall rotating speed will be scraped afterwards and drop to 30 revs/min, and be cooled to 45 DEG C under this rotating speed;
(4) then add the self-control A extracting solution of formula ratio and make D extracting solution and co-emulsifier by oneself, stir 30 minutes under the rotating speed of 25 revs/min, continue afterwards to cool to 40 DEG C, add antiseptic and the essence of formula ratio, continue to stir 20 minutes under same rotating speed, get final product discharging, obtained Folium Artemisiae Argyi protective skin cream.
embodiment 3
The preparation method of making A extracting solution in the present embodiment by oneself comprises the following steps:
(1) Mao Pu, scutellariae,radix, Radix Sophorae Flavescentis coarse powder are broken into≤segment of 3cm or the small pieces of diameter≤3cm, take Folium Artemisiae Argyi 6 parts, Rhizoma Acori Graminei 5 parts, scutellariae,radix, each 5 parts of Radix Sophorae Flavescentis, propylene glycol 14 parts, volumetric concentration is the alcoholic solution 650 parts of 75%, at 75 DEG C, reflux alcohol extraction 1.5 hours, with obtain respectively after 600 order filter-cloth filterings filtering residue 1. with alcohol extract 1.;
(2) filtering residue obtained in described step (1) 1. in add volumetric concentration be 75% alcoholic solution 550 parts, propylene glycol 8 parts, at 75 DEG C, reflux alcohol extraction 2 hours, with obtain after 600 order filter-cloth filterings filtering residue 2. with alcohol extract 2.;
(3) by described alcohol extract 1., 2. alcohol extract merge post-heating concentration and recovery ethanol, when liquid to be mixed is concentrated to 35 parts, must make Folium Artemisiae Argyi, Rhizoma Acori Graminei, scutellariae,radix, the ethanol of Radix Sophorae Flavescentis and the concentrated solution of propylene glycol extraction liquid by oneself, called after self-control A extracting solution;
(4) filtering residue obtained in described step (2) 2. in add 350 parts of deionized waters, be heated to boiling, and remain on slight boiling condition and boil 0.8 hour, then with 600 order filter-cloth filterings namely obtain filtering residue 3. with Aqueous extracts 1.;
(5) step (4) gained filtering residue 3. in add the deionized water of 280 parts again, be heated to boiling, and boil 0.5 hour at slight boiling condition, then with 600 order filter-cloth filterings namely obtain filtering residue 4. and Aqueous extracts 2.;
(6) by Aqueous extracts 1., Aqueous extracts namely obtain after 2. merging self-control Folium Artemisiae Argyi, Rhizoma Acori Graminei, scutellariae,radix, Radix Sophorae Flavescentis Aqueous extracts, control water evaporation quantity, make the Aqueous extracts total amount finally concentrating molding be add total Water 1/3, B extracting solution must be made by oneself.
The preparation method of making C extracting solution in the present embodiment by oneself comprises the following steps:
(1) 8 parts, Radix Glycyrrhizae is taken, wild soybean seed 4 parts, oat kernel 5 parts, each 4 parts of root of Paeonia suffruticosa Ardr., althaea root, Herba Houttuyniae, Neem leaves, Sakura leaf, leaf of Herb Gynostemmae Pentaphylli, very thin Herba Erodii, Centaurea cyanus, Herba Taraxaci, Rhizoma Saururi (Herba Saururi), each 1 part of Herba Portulacae, will join in enamel Chinese medicine extracting tank after partial block in these Chinese medicines, the segment of coarse crushing one-tenth≤3cm that leaf is larger or the small pieces of diameter≤3cm;
(2) first time is when boiling, and takes deionized water 680 parts and adds in enamel Chinese medicine extracting tank, soaks 30 minutes post-heating to seething with excitement, and remains on slight boiling condition and boil 1.0 hours, then with 600 order filter-cloth filterings namely obtain water extraction filtering residue 1. with Aqueous extracts 1.;
(3) the obtained water extraction filtering residue of step (2) 1. in add the deionized water of 580 parts again, be heated to boiling, and remain on slight boiling condition and boil 0.6 hour, then with 600 order filter-cloth filterings namely obtain water extraction filtering residue 2. with Aqueous extracts 2.;
(4) by above-mentioned Aqueous extracts 1., namely 2. Aqueous extracts obtain self-control Chinese traditional medicine water extract after mix homogeneously, control water evaporates amount, make the Aqueous extracts total amount finally concentrating molding be the half adding the water yield, C extracting solution must be made by oneself.
The preparation method of making D extracting solution in the present embodiment by oneself comprises the following steps: (1) described water extraction filtering residue 2. in add sucrose 6 parts, glucose 3 parts, dipotassium hydrogen phosphate 0.3 part, 0.2 part, sodium chloride, pure water 350 parts, be heated to boiling, constant temperature disinfection 20 minutes, then 33 DEG C are cooled to, add 90 parts of self-control C extracting solution, (2) (strain is purchased from Chinese industrial Culture Collection then to press the Aureobasidium pullulans strain after the inoculum concentration access amplification culture of 3% of fermentation bed material total amount, bacterium numbering: CICC41349), fermentation culture is after 2 days, (strain is purchased from Chinese industrial Culture Collection to add the Pichia sp. strain of 1% of fermentation bed material total amount again, bacterium numbering: CICC33024) and fermentation bed material total amount 3% Lactobacillus plantarum strain ((strain is purchased from Chinese industrial Culture Collection, bacterium numbering: CICC6240)), continue fermentation culture 3 days, and then system temperature is dropped to 29 DEG C, continue fermentation and add self-control B extracting solution and filtering residue after 2 days 4., continue fermentation 3 days, get fermentation liquid inspection thalline sum, if be greater than 500CFU/ML, continue fermentation 5 days or use ozone sterilization system for handling, until viable bacteria body approach exhaustion in system, until thalline sum≤500CFU/ML in system, then fermentation liquid is crossed 600 order filter clothes to leach, (3) then below 50 DEG C vacuum concentration to 1/2 of total fermentation filtrate volume, the concentrated solution of obtained fermented extracted liquid, namely D extracting solution is made by oneself.
The present embodiment Folium Artemisiae Argyi protective skin cream, substitutes the pure water component in Folium Artemisiae Argyi protective skin cream, is made up of the component of following weight portion with obtained C extracting solution:
(1) oil phase component: described oil phase component is made up of the component of following weight parts: 16 mixed alcohols 1 part, 16 stearyl alcohol and 16 octadecyl glucosides 4 parts, tristerin and PEG-100 stearate 3 parts, Jojoba oil 3 parts, isomery hexadecane hydrocarbon 2 parts, seed of Flos Camelliae Japonicae oil 2 parts, Oleum Perillae 1 part, isopropyl myristate 1 part, dimethicone 2 parts, methyl hydroxybenzoate 0.2 part, propylparaben 0.15 part, ditertbutylparacresol 0.03 part;
(2) water phase components: described water phase components is made up of the component of following weight parts: glycerol 7 parts, 2 parts, modified corn syrup (commodity English name: MOISYRUP, Shun Tuo scientific & trading Co., Ltd. provides by Shanghai), trehalose 2 parts, trimethyl glycine 2 parts, self-control C extracting solution 55 parts;
(3) extracting solution component: self-control A extracting solution 2 parts, self-control D extracting solution 10 parts;
(4) co-emulsifier component: hydroxy acrylic acid brine and sodium acryloyldimethyl taurate copolymers 0.5 part;
(5) antiseptic: 0.1 part, the mixture of MIT and 3-iodo-2-propynyl butyl carbamate;
(6) essence: floral perfume 0.02 part.
The preparation method of the present embodiment Folium Artemisiae Argyi protective skin cream, comprises the steps:
(1) preparation of oil phase component: 16 mixed alcohols of formula ratio, 16 stearyl alcohol and 16 octadecyl glucosides, tristerin and PEG-100 stearate, Jojoba oil, isomery hexadecane hydrocarbon, seed of Flos Camelliae Japonicae oil, Oleum Perillae, Semen Myristicae propyl ester, dimethicone, methyl hydroxybenzoate, propylparaben, ditertbutylparacresol are added in the rustless steel still of band stirring after taking in proportion, under the stirring of rotating speed 25 revs/min, heating for dissolving is complete, and constant temperature disinfection 20 minutes is stand-by at 85 DEG C;
(2) preparation of water phase components: the glycerol of formula ratio, modified corn syrup, trehalose, trimethyl glycine, self-control C extracting solution are taken rear elder generation heating for dissolving in rustless steel still in proportion, then be extracted in rustless steel homogenizing still, under the stirring of 30 revs/min, continue to be heated to 85 DEG C, and constant temperature disinfection 20 minutes is stand-by;
(3) by oil phase slowly suction aqueous phase, and carry out scraping wall and stir, stir 3 minutes scraping under wall rotating speed is 45 revs/min, start high speed homogenization device homogenizing 5 minutes under the high speed of 3000 revs/min, wall rotating speed will be scraped afterwards and drop to 40 revs/min, and be cooled to 50 DEG C under this rotating speed;
(4) then add the self-control A extracting solution of formula ratio and make D extracting solution and co-emulsifier by oneself, stir 20 minutes under the rotating speed of 30 revs/min, continue afterwards to cool to 40 DEG C, add antiseptic and the essence of formula ratio, continue to stir 20 minutes under same rotating speed, get final product discharging, obtained Folium Artemisiae Argyi protective skin cream.
embodiment 4
The preparation method of making A extracting solution in the present embodiment by oneself comprises the following steps:
(1) Mao Pu, scutellariae,radix, Radix Sophorae Flavescentis coarse powder are broken into≤segment of 3cm or the small pieces of diameter≤3cm, take Folium Artemisiae Argyi 5 parts, Rhizoma Acori Graminei 3 parts, scutellariae,radix, each 6 parts of Radix Sophorae Flavescentis, propylene glycol 10 parts, volumetric concentration is the alcoholic solution 600 parts of 60%, at 70 DEG C, reflux alcohol extraction 1 hour, with obtain respectively after 600 order filter-cloth filterings filtering residue 1. with alcohol extract 1.;
(2) filtering residue obtained in described step (1) 1. in add volumetric concentration be 60% alcoholic solution 500 parts, propylene glycol 5 parts, at 70 DEG C, reflux alcohol extraction 3 hours, with obtain after 600 order filter-cloth filterings filtering residue 2. with alcohol extract 2.;
(3) by described alcohol extract 1., 2. alcohol extract merge post-heating concentration and recovery ethanol, when liquid to be mixed is concentrated to 50 parts, must make Folium Artemisiae Argyi, Rhizoma Acori Graminei, scutellariae,radix, the ethanol of Radix Sophorae Flavescentis and the concentrated solution of propylene glycol extraction liquid by oneself, called after self-control A extracting solution;
(4) filtering residue obtained in described step (2) 2. in add 300 parts of deionized waters, be heated to boiling, and remain on slight boiling condition and boil 0.9 hour, then with 600 order filter-cloth filterings namely obtain filtering residue 3. with Aqueous extracts 1.;
(5) step (4) gained filtering residue 3. in add the deionized water of 300 parts again, be heated to boiling, and boil 0.8 hour at slight boiling condition, then with 600 order filter-cloth filterings namely obtain filtering residue 4. and Aqueous extracts 2.;
(6) by Aqueous extracts 1., Aqueous extracts namely obtain after 2. merging self-control Folium Artemisiae Argyi, Rhizoma Acori Graminei, scutellariae,radix, Radix Sophorae Flavescentis Aqueous extracts, control water evaporation quantity, make the Aqueous extracts total amount finally concentrating molding be add total Water 1/3, B extracting solution must be made by oneself.
The preparation method of making C extracting solution in the present embodiment by oneself comprises the following steps:
(1) 10 parts, Radix Glycyrrhizae is taken, wild soybean seed 5 parts, oat kernel 4 parts, each 4 parts of root of Paeonia suffruticosa Ardr., althaea root, Herba Houttuyniae, Neem leaves, Sakura leaf, leaf of Herb Gynostemmae Pentaphylli, very thin Herba Erodii, Centaurea cyanus, Herba Taraxaci, Rhizoma Saururi (Herba Saururi), each 2 parts of Herba Portulacae, will join in enamel Chinese medicine extracting tank after partial block in these Chinese medicines, the segment of coarse crushing one-tenth≤3cm that leaf is larger or the small pieces of diameter≤3cm;
(2) first time is when boiling, and takes deionized water 700 parts and adds in enamel Chinese medicine extracting tank, soaks 30 minutes post-heating to seething with excitement, and remains on slight boiling condition and boil 0.8 hour, then with 600 order filter-cloth filterings namely obtain water extraction filtering residue 1. with Aqueous extracts 1.;
(3) the obtained water extraction filtering residue of step (2) 1. in add the deionized water of 500 parts again, be heated to boiling, and remain on slight boiling condition and boil 0.8 hour, then with 600 order filter-cloth filterings namely obtain water extraction filtering residue 2. with Aqueous extracts 2.;
(4) by above-mentioned Aqueous extracts 1., namely 2. Aqueous extracts obtain self-control Chinese traditional medicine water extract after mix homogeneously, control water evaporates amount, make the Aqueous extracts total amount finally concentrating molding be the half adding the water yield, C extracting solution must be made by oneself.
The preparation method of making D extracting solution in the present embodiment by oneself comprises the following steps: (1) described water extraction filtering residue 2. in add sucrose 5 parts, glucose 4 parts, dipotassium hydrogen phosphate 0.4 part, 0.1 part, sodium chloride, pure water 300 parts, be heated to boiling, constant temperature disinfection 20 minutes, then 30 DEG C are cooled to, add 50 parts of self-control C extracting solution, (2) (strain is purchased from Chinese industrial Culture Collection then to press the Aureobasidium pullulans strain after the inoculum concentration access amplification culture of 2% of fermentation bed material total amount, bacterium numbering: CICC41349), fermentation culture is after 1 day, (strain is purchased from Chinese industrial Culture Collection to add the Pichia sp. strain of 2% of fermentation bed material total amount again, bacterium numbering: CICC33024) and fermentation bed material total amount 1% Lactobacillus plantarum strain ((strain is purchased from Chinese industrial Culture Collection, bacterium numbering: CICC6240)), continue fermentation culture 1 day, and then system temperature is dropped to 28 DEG C, continue fermentation and add self-control B extracting solution and filtering residue after 1 day 4., continue fermentation 2 days, get fermentation liquid inspection thalline sum, if be greater than 500CFU/ML, continue fermentation 3 days or use ozone sterilization system for handling, until viable bacteria body approach exhaustion in system, until thalline sum≤500CFU/ML in system, then fermentation liquid is crossed 600 order filter clothes to leach, (3) then below 50 DEG C vacuum concentration to 1/2 of total fermentation filtrate volume, the concentrated solution of obtained fermented extracted liquid, namely D extracting solution is made by oneself.
The present embodiment Folium Artemisiae Argyi protective skin cream, be made up of the component of following weight portion:
(1) oil phase component: described oil phase component is made up of the component of following weight parts: 16 mixed alcohols 1.2 parts, 16 stearyl alcohol and 16 octadecyl glucosides 2 parts, tristerin and PEG-100 stearate 2 parts, Jojoba oil 2 parts, isomery hexadecane hydrocarbon 2 parts, seed of Flos Camelliae Japonicae oil 1 part, Oleum Perillae 1 part, isopropyl myristate 1 part, dimethicone 2 parts, methyl hydroxybenzoate 0.2 part, propylparaben 0.1 part, ditertbutylparacresol 0.05 part;
(2) water phase components: described water phase components is made up of the component of following weight parts: glycerol 5 parts, 2 parts, modified corn syrup (commodity English name: MOISYRUP, Shun Tuo scientific & trading Co., Ltd. provides by Shanghai), trehalose 1 part, trimethyl glycine 2 parts, self-control C extracting solution 40 parts;
(3) extracting solution component: self-control A extracting solution 2 parts, self-control D extracting solution 5 parts;
(4) co-emulsifier component: hydroxy acrylic acid brine and sodium acryloyldimethyl taurate copolymers 1 part;
(5) antiseptic: 0.15 part, the mixture of MIT and 3-iodo-2-propynyl butyl carbamate;
(6) essence: floral perfume 0.01 part.
The preparation method of the present embodiment Folium Artemisiae Argyi protective skin cream, comprises the steps:
(1) preparation of oil phase component: 16 mixed alcohols of formula ratio, 16 stearyl alcohol and 16 octadecyl glucosides, tristerin and PEG-100 stearate, Jojoba oil, isomery hexadecane hydrocarbon, seed of Flos Camelliae Japonicae oil, Oleum Perillae, Semen Myristicae propyl ester, dimethicone, methyl hydroxybenzoate, propylparaben, ditertbutylparacresol are added in the rustless steel still of band stirring after taking in proportion, under the stirring of rotating speed 20 revs/min, heating for dissolving is complete, and constant temperature disinfection 20 minutes is stand-by at 80 DEG C;
(2) preparation of water phase components: the glycerol of formula ratio, modified corn syrup, trehalose, trimethyl glycine, self-control C extracting solution are taken rear elder generation heating for dissolving in rustless steel still in proportion, then be extracted in rustless steel homogenizing still, under the stirring of 20 revs/min, continue to be heated to 80 DEG C, and constant temperature disinfection 20 minutes is stand-by;
(3) by oil phase slowly suction aqueous phase, and carry out scraping wall and stir, stir 2 minutes scraping under wall rotating speed is 40 revs/min, start high speed homogenization device homogenizing 4 minutes under the high speed of 3500 revs/min, wall rotating speed will be scraped afterwards and drop to 30 revs/min, and be cooled to 47 DEG C under this rotating speed;
(4) then add the self-control A extracting solution of formula ratio and make D extracting solution and co-emulsifier by oneself, stir 25 minutes under the rotating speed of 20 revs/min, continue afterwards to cool to 40 DEG C, add antiseptic and the essence of formula ratio, continue to stir 15 minutes under same rotating speed, get final product discharging, obtained Folium Artemisiae Argyi protective skin cream.
Claims (5)
1. a Folium Artemisiae Argyi protective skin cream, is characterized in that being made up of the component of following weight portion:
(1) oil phase component: described oil phase component is made up of the component of following weight parts: 16 mixed alcohols 1 ~ 1.5 part, 16 stearyl alcohol and 16 octadecyl glucosides 2 ~ 4 parts, tristerin and PEG-100 stearate 2 ~ 3 parts, Jojoba oil 2 ~ 4 parts, isomery hexadecane hydrocarbon 2 ~ 4 parts, seed of Flos Camelliae Japonicae oil 1 ~ 3 part, Oleum Perillae 1 ~ 2 part, isopropyl myristate 1 ~ 3 part, dimethicone 2 ~ 4 parts, methyl hydroxybenzoate 0.2 ~ 0.3 part, propylparaben 0.1 ~ 0.15 part, ditertbutylparacresol 0.03 ~ 0.05 part;
(2) water phase components: described water phase components is made up of the component of following weight parts: glycerol 5 ~ 8 parts, 2 ~ 4 parts, modified corn syrup, trehalose 1 ~ 2 part, trimethyl glycine 2 ~ 4 parts, self-control C extracting solution 40 ~ 60 parts, described self-control C extracting solution is made up of the raw material of following weight portion: 5 ~ 10 parts, Radix Glycyrrhizae, wild soybean seed 3 ~ 5 parts, oat kernel 4 ~ 5 parts, each 3 ~ 4 parts of root of Paeonia suffruticosa Ardr., althaea root, Herba Houttuyniae, Neem leaves, Sakura leaf, leaf of Herb Gynostemmae Pentaphylli, very thin Herba Erodii, Centaurea cyanus, Herba Taraxaci, Rhizoma Saururi (Herba Saururi), each 1 ~ 3 part of Herba Portulacae;
(3) extracting solution component: self-control A extracting solution 2 ~ 4 parts, self-control D extracting solution 5 ~ 10 parts;
(4) co-emulsifier component: hydroxy acrylic acid brine and sodium acryloyldimethyl taurate copolymers 0.5 ~ 1 part;
(5) antiseptic: mixture 0.1-0.15 part of MIT and 3-iodo-2-propynyl butyl carbamate;
(6) essence: floral perfume 0.01-0.02 part.
2. the preparation method of Folium Artemisiae Argyi protective skin cream according to claim 1, is characterized in that comprising the steps:
(1) preparation of oil phase component: 16 mixed alcohols of formula ratio, 16 stearyl alcohol and 16 octadecyl glucosides, tristerin and PEG-100 stearate, Jojoba oil, isomery hexadecane hydrocarbon, seed of Flos Camelliae Japonicae oil, Oleum Perillae, Semen Myristicae propyl ester, dimethicone, methyl hydroxybenzoate, propylparaben, ditertbutylparacresol are added in the rustless steel still of band stirring after taking in proportion, under the stirring of rotating speed 20 ~ 30 revs/min, heating for dissolving is complete, and constant temperature disinfection 20 minutes is stand-by at 80 ~ 85 DEG C;
(2) preparation of water phase components: the glycerol of formula ratio, modified corn syrup, trehalose, trimethyl glycine, self-control C extracting solution are taken rear elder generation heating for dissolving in rustless steel still in proportion, then be extracted in rustless steel homogenizing still, under the stirring of 20 ~ 30 revs/min, continue to be heated to 80 ~ 85 DEG C, and constant temperature disinfection 20 minutes is stand-by;
(3) by oil phase suction aqueous phase, and carry out scraping wall and stir, stir 2-3 minute scraping under wall rotating speed is 40-50 rev/min, start high speed homogenization device homogenizing 3-5 minute under the high speed of 3000-5000 rev/min, wall rotating speed will be scraped afterwards and drop to 30-40 rev/min, and be cooled to 45-50 DEG C under this rotating speed;
(4) then add the self-control A extracting solution of formula ratio and make D extracting solution and co-emulsifier by oneself, 20-30 minute is stirred under the rotating speed of 20-30 rev/min, continue afterwards to cool to 40 DEG C, add antiseptic and the essence of formula ratio, continue to stir 15-20 minute under same rotating speed, get final product discharging, obtained Folium Artemisiae Argyi protective skin cream.
3. the preparation method of Folium Artemisiae Argyi protective skin cream according to claim 2, is characterized in that: the preparation method of described self-control A extracting solution comprises the following steps:
(1) Folium Artemisiae Argyi 5 ~ 8 parts is taken, Rhizoma Acori Graminei 3 ~ 6 parts, scutellariae,radix, each 4 ~ 6 parts of Radix Sophorae Flavescentis, propylene glycol 10 ~ 15 parts, volumetric concentration is the alcoholic solution 600 ~ 700 parts of 60% ~ 80%, at 70 ~ 90 DEG C, reflux alcohol extraction 1 ~ 3 hour, with obtain respectively after 600 order filter-cloth filterings filtering residue 1. with alcohol extract 1.;
(2) filtering residue obtained in described step (1) 1. in add volumetric concentration be 60% ~ 80% alcoholic solution 500 ~ 600 parts, propylene glycol 5 ~ 10 parts, at 70 ~ 90 DEG C, reflux alcohol extraction 1 ~ 3 hour, with obtain after 600 order filter-cloth filterings filtering residue 2. with alcohol extract 2.;
(3) by described alcohol extract 1., 2. alcohol extract merge post-heating concentration and recovery ethanol, when liquid to be mixed is concentrated to 30 ~ 50 parts, must make Folium Artemisiae Argyi, Rhizoma Acori Graminei, scutellariae,radix, the ethanol of Radix Sophorae Flavescentis and the concentrated solution of propylene glycol extraction liquid by oneself, called after self-control A extracting solution;
(4) filtering residue obtained in described step (2) 2. in add 300 ~ 400 parts of deionized waters, be heated to boiling, and remain on slight boiling condition and boil 0.8 ~ 1.0 hour, then with 600 order filter-cloth filterings namely obtain filtering residue 3. with Aqueous extracts 1.;
(5) step (4) gained filtering residue 3. in add the deionized water of 200 ~ 300 parts again, be heated to boiling, and boil 0.5 ~ 0.8 hour at slight boiling condition, then with 600 order filter-cloth filterings namely obtain filtering residue 4. and Aqueous extracts 2.;
(6) by Aqueous extracts 1., Aqueous extracts namely obtain after 2. merging self-control Folium Artemisiae Argyi, Rhizoma Acori Graminei, scutellariae,radix, Radix Sophorae Flavescentis Aqueous extracts, control water evaporation quantity, make the Aqueous extracts total amount finally concentrating molding be add total Water 1/3, B extracting solution must be made by oneself.
4. the preparation method of Folium Artemisiae Argyi protective skin cream according to claim 3, is characterized in that: the preparation method of described self-control C extracting solution comprises the following steps:
(1) 5 ~ 10 parts, Radix Glycyrrhizae is taken, wild soybean seed 3 ~ 5 parts, oat kernel 4 ~ 5 parts, each 3 ~ 4 parts of root of Paeonia suffruticosa Ardr., althaea root, Herba Houttuyniae, Neem leaves, Sakura leaf, leaf of Herb Gynostemmae Pentaphylli, very thin Herba Erodii, Centaurea cyanus, Herba Taraxaci, Rhizoma Saururi (Herba Saururi), each 1 ~ 3 part of Herba Portulacae, join in enamel Chinese medicine extracting tank;
(2) when first time boils, taking deionized water 600 ~ 700 parts adds in enamel Chinese medicine extracting tank, soak 30 minutes post-heating to boiling, and remain on slight boiling condition and boil 0.8 ~ 1.0 hour, then with 600 order filter-cloth filterings namely obtain water extraction filtering residue 1. with Aqueous extracts 1.;
(3) the obtained water extraction filtering residue of step (2) 1. in add the deionized water of 500 ~ 600 parts again, be heated to boiling, and remain on slight boiling condition and boil 0.6 ~ 0.8 hour, then with 600 order filter-cloth filterings namely obtain water extraction filtering residue 2. with Aqueous extracts 2.;
(4) by above-mentioned Aqueous extracts 1., namely 2. Aqueous extracts obtain self-control Chinese traditional medicine water extract after mix homogeneously, control water evaporates amount, make the Aqueous extracts total amount finally concentrating molding be the half adding the water yield, C extracting solution must be made by oneself.
5. the preparation method of Folium Artemisiae Argyi protective skin cream according to claim 4, it is characterized in that: the preparation method of described self-control D extracting solution comprises the following steps: (1) described water extraction filtering residue 2. in add sucrose 5 ~ 8 parts, glucose 3 ~ 5 parts, dipotassium hydrogen phosphate 0.3 ~ 0.5 part, 0.1 ~ 0.2 part, sodium chloride, pure water 300 ~ 400 parts, be heated to boiling, constant temperature disinfection 20 minutes, then 30 ~ 35 DEG C are cooled to, add 50 ~ 100 parts of self-control C extracting solution, (2) the Aureobasidium pullulans strain after the inoculum concentration access amplification culture of 2 ~ 3% of fermentation bed material total amount is then pressed, fermentation culture is after 1 ~ 3 day, add the Lactobacillus plantarum strain of the Pichia sp. strain of 1 ~ 2% of fermentation bed material total amount and 1 ~ 3% of fermentation bed material total amount again, continue fermentation culture 1 ~ 3 day, and then system temperature is dropped to 28 ~ 30 DEG C, continue fermentation and add self-control B extracting solution and filtering residue after 1 ~ 2 day 4., continue fermentation 2 ~ 3 days, until thalline sum≤500CFU/ML in system, then fermentation liquid is crossed 600 order filter clothes to leach, (3) then below 50 DEG C vacuum concentration to 1/2 of total fermentation filtrate volume, the concentrated solution of obtained fermented extracted liquid, namely D extracting solution is made by oneself.
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| CN107970170A (en) * | 2017-12-28 | 2018-05-01 | 广东医科大学 | The preparation method of sleep mask and its facial mask liquid |
| CN112043645A (en) * | 2020-10-06 | 2020-12-08 | 青岛姿之妍化妆品科技有限责任公司 | Skin care composition |
| CN113749998A (en) * | 2020-06-06 | 2021-12-07 | 伍新维 | Composite acne-removing cream and preparation method thereof |
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| CN106727132A (en) * | 2016-12-23 | 2017-05-31 | 严志海 | A kind of gentle moisturizing mildy wash and preparation method thereof |
| CN107970170A (en) * | 2017-12-28 | 2018-05-01 | 广东医科大学 | The preparation method of sleep mask and its facial mask liquid |
| CN113749998A (en) * | 2020-06-06 | 2021-12-07 | 伍新维 | Composite acne-removing cream and preparation method thereof |
| CN112043645A (en) * | 2020-10-06 | 2020-12-08 | 青岛姿之妍化妆品科技有限责任公司 | Skin care composition |
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| Publication number | Publication date |
|---|---|
| CN104873433B (en) | 2018-04-20 |
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