KR102235623B1 - Health care food and method for manufacturing thereof - Google Patents

Abstract

The present invention relates to a health supplement food and a manufacturing method. More specifically, the health supplement food comprises 8-12 wt% of a black ginseng concentrate, 3-7 wt% of a fish collagen peptide, 1-5 wt% of a thickener and the remainder of a cherry concentrate. According to the health supplement food and the manufacturing method of the present invention, the health supplement food is rich in various nutritional and medicinal ingredients, has excellent antioxidant and anti-inflammatory activity, can prevent and alleviate high blood pressure, and can induce good sleep, thereby promoting the health of consumers.

Description

Health supplement food containing black ginseng concentrate and cherry concentrate and its manufacturing method {HEALTH CARE FOOD AND METHOD FOR MANUFACTURING THEREOF}

The present invention relates to a health supplement and a method for manufacturing the same, and more particularly, by preparing a concentrate of cherry and black ginseng having excellent anti-inflammatory and antioxidant activity as health supplements, various nutrients and medicinal ingredients of cherry and black ginseng are prepared. It relates to a health supplement that enables steady intake and a method of manufacturing the same.

Recently, as the standard of living has increased and the diet has become westernized, the incidence of lifestyle-related diseases (adult diseases) such as obesity, diabetes, high blood pressure and heart disease due to excess nutrition and lack of exercise is increasing. In addition, as the speed of entry into an aging society is accelerating due to the prolongation of life expectancy, interest in health promotion is increasing.

Accordingly, there is an increasing demand for health functional foods using red ginseng, glucosamine, and vitamins.

On the other hand, cherry means a plant belonging to the genus Rosaceae Prunus, Prunus pauciflora Bunge, Prunus avium, Prunus cerasus L. or Prunus cerasus L. And plants having the scientific name of Prunus effusa K. Schneider. As it contains a large amount of red anthocyanins, it has antioxidant, anti-inflammatory, and anti-aging effects, and contains melatonin, which can help reduce body fatigue and maintain health.

These cherries have poor storage properties, making it difficult to consume them consistently throughout the four seasons. To solve this problem, cherries are juiced and consumed as juice, or processed into a powder form and consumed in a juice form.

In addition, black ginseng is made by processing red ginseng, and ginsenosides Rb, Rc, Rd, Re, Rg1, etc., which are present in a large amount in red ginseng, are pyrolyzed during processing and converted into ginsenosides Rg2, Rg3, Rh, etc. Ginsenoside Rg3 content is enhanced. The main effects of black ginseng are known to have nourishing and tonic effects, improving sexual and reproductive dysfunction, anti-cancer effect, improving liver dysfunction, relieving hangovers, preventing parasite infection, and analgesic and anti-inflammatory effects.

Conventionally, such black ginseng has been used alone and processed into beverage compositions, slices, tea, health supplements, and the like.

However, in the past, no other health supplement food that combines cherry and black ginseng has been found.

KR 10-1302513 B1 KR 10-2107387 B1 KR 10-2014824 B1 KR 10-1563310 B1

It is an object of the present invention to prepare a health supplement food by combining cherry concentrate, black ginseng concentrate and collagen peptide, which has excellent antioxidant, anti-inflammatory and anti-aging activity, and is rich in various nutrients and medicinal ingredients, and a method of manufacturing the same. To provide.

In addition, it is to prevent and improve hypertension, to induce a good night's sleep to improve the quality of life to provide a health supplement and a method of manufacturing the same.

The health supplement of the present invention for achieving the above object is characterized in that it comprises 8 to 12% by weight of black ginseng concentrate, 3 to 7% by weight of fish collagen peptide, 1 to 5% by weight of thickener, and the balance of cherry concentrate. .

It characterized in that it further comprises 1 to 5% by weight of leather tree extract and 1 to 5% by weight of echinacea extract.

It is characterized in that it further comprises 1 to 5% by weight of mountain spleen extract.

The method of manufacturing a health supplement according to the present invention includes the steps of mixing cherry concentrate and black ginseng concentrate, adding fish collagen peptide and a thickener to the mixed mixture, and filtering the mixed mixture. , Including the step of sterilizing the filtered mixture at 92 ~ 94 ℃, the amount of each material, black ginseng concentrate 8 ~ 12% by weight, fish collagen peptide 3 ~ 7% by weight, thickener 1 ~ 5% by weight and the balance It is characterized in that it is a cherry concentrate.

In the step of mixing by adding fish collagen peptide and a thickener to the mixed mixture, leather tree extract, echinacea extract, and mountain spleen extract are further mixed, the amount of which is 1-5% by weight of leather tree extract, echinacea extract 1 to 5% by weight and 1 to 5% by weight of mountain spleen extract, the black ginseng concentrate was obtained by adding water to black ginseng, extracted for 5 to 24 hours at 70 to 100°C, and concentrated in persimmon, the fish collagen peptide It is obtained by hydrolysis reaction by adding enzyme to fish collagen, and has an average molecular weight of 200 Da to 1,000 Da, and the cherry concentrate is juiced from cherries and concentrated under reduced pressure, and the leather tree extract, echinacea extract, and mountain spleen extract It is characterized in that it is extracted using at least one of silver, water, and alcohol having 1 to 4 carbon atoms as a solvent.

According to the health supplement and its manufacturing method of the present invention, it is rich in various nutrient and medicinal ingredients, has excellent antioxidant and anti-inflammatory activity, prevents and improves hypertension, and can induce a good night's sleep, thereby promoting the health of the ingestion. There is an advantage of being able to do it.

1 to 4 are graphs showing the results of the test according to the present invention.

Hereinafter, the present invention will be described in detail.

The health supplement food according to the present invention is rich in various nutrient and medicinal ingredients to help maintain the health of the eater, and is characterized by its excellent antioxidant and anti-inflammatory activity.

The health supplement of the present invention as described above is characterized in that it comprises 8 to 12% by weight of black ginseng concentrate, 3 to 7% by weight of fish collagen peptide, 1 to 5% by weight of thickener, and the balance of cherry concentrate.

First, the black ginseng concentrate is rich in ginsenosides Rg1, Rg2, and Rg3. In the present invention, a black ginseng concentrate having Rg1, Rg2 and Rg3 content of 6 mg/g or more, preferably 6 to 30 mg/g is used. At this time, the black ginseng concentrate is prepared by adding water at 70 to 100°C in 2 to 20 weight times to black ginseng, extracting for 5 to 24 hours, and then concentrating under reduced pressure at about 60 to 65°C.

The black ginseng concentrate is contained in 8 to 12% by weight in health supplements, and if the content is less than 8% by weight, the antioxidant and anti-inflammatory activity is not sufficient, and if it exceeds 12% by weight, the content of other ingredients is relatively reduced. This is because the functionality is deteriorated.

The fish collagen peptide is obtained by hydrolysis reaction by adding an enzyme to fish collagen, and has the advantage of rapid absorption in the body due to a low molecular weight. These fish collagen peptides have the effect of imparting elasticity to the skin and preventing aging.

More specifically, in the fish collagen peptide, at least one selected from the group consisting of proteases collagenase, trypsin, papain, pepsin and alcalase is added to fish collagen, and hydrolyzed at 50 to 70°C for 2 to 24 hours. By proceeding the decomposition reaction, fish collagen peptides are prepared. In addition, purification and drying processes can be added as needed. These collagen peptides have an average molecular weight of 200-1,000 Da, enabling rapid absorption into the body, and easy intake because there is no fishy taste due to hydrolysis.

The fish collagen peptide is included in 3 to 7% by weight in the health supplement.

The thickener is for improving the viscosity of the product, and at least one of locust bean gum, carrageenan, tamarind gum, xanthan gum, and agar may be used. The thickener is included in 1 to 5% by weight in the health supplement.

The cherry concentrate is the main ingredient of the health supplement according to the present invention, and contains a large amount of anthocyanins to provide excellent anti-inflammatory, antioxidant and anti-aging activities, as well as melatonin to reduce body fatigue and help maintain health. Gives It also induces a good night's sleep.

This cherry concentrate is a cherry juice, concentrated under reduced pressure, and is included as a balance in health supplements. At this time, the type of cherry is not limited, and various types such as winter cherry and tart cherry can be used. In the present invention, a tart cherry concentrate will be described as an example.

As described above, health supplements including black ginseng concentrate, fish collagen peptide, thickener and cherry concentrate have the advantage of having excellent anti-inflammatory, antioxidant and anti-aging activities. In addition, there is an advantage in that it has an effect of not only inducing sleep, but also improving hypertension through the harmony of the above ingredients.

However, in order to further enhance the sleep-inducing effect and the effect of improving hypertension, the health supplement of the present invention may further include a leather tree extract and an echinacea extract.

The leather tree (Ailanthus altissima) is a deciduous tree of the family Simarou ba ceae and is also called a weight tree. It contains phenolic substances such as 4,5-trimethoxyphenol, p-comeric acid, vanillin, and vanillic acid, merosine, tannin propbafen, and alantone. It is a known fact that these extracts of leather wood exhibit excellent antioxidant effects and increase skin immunity. In the present invention, as well as improving the antioxidant effect, through the interaction with the cherry concentrate, echinacea extract, black ginseng concentrate, and the like, excellent hypertension improvement and sleep-inducing effects are provided.

The extract of the leather tree can be prepared by adding one or more solvents of 10 to 50 times by weight of water and alcohol having 1 to 4 carbon atoms to the leaves of the leather tree, extracting and filtering at 30 to 100°C for 3 to 12 hours, , It is natural that it can be concentrated and dried as needed. In addition, it is natural that it may be prepared through various known methods for preparing extracts from other natural products.

When considering its efficacy, the extract of the leather tree is preferably contained in 1 to 5% by weight in a health supplement.

The Echinacea ( Echinacea purpurea) has long been used as a traditional folk medicine for various diseases by Native Americans in North America, and 9 types of Echinacea plants are known, of which 3 species ( Echinacea angustifolia, Echinacea pallida, Echinacea purpurea). ) Is mainly used for medicinal purposes. In the present invention, the type of echinacea is not limited. The echinacea extract is reported to have antioxidant, antibacterial, antiviral, antifungal, and anti-inflammatory effects. The immune function of echinacea extract has been reported to affect the metabolism of granulocytes, lymphocytes, monocytes and macrophages. According to the reported research results, echinacea extracts contain nitric oxide (Nitric Oxide) and Il-1, Il-6. , Il-8, Il-12, and promotes the secretion of cytokines such as TNF-α and increases the activity of macrophages (macrophages) has been reported to help strengthen immunity. The main active ingredient of echinacea extract is a derivative of Caffeic Acid, a polyphenol, and includes ingredients such as Caftaric acid, Chlorogenic acid, Cynarin, Echinacoside, and Cichoric acid. In the present invention, as well as improving the anti-inflammatory effect, through the interaction with the cherry concentrate, leather tree extract, black ginseng concentrate, and the like, excellent hypertension improvement and sleep-inducing effect are provided.

The echinacea extract can be extracted in the same manner as the leather tree extract using the echinacea outpost, and when considering its efficacy, it is preferably contained in 1 to 5% by weight in a health supplement.

In addition, the health supplement food of the present invention may further include a sanbijang extract.

The mountain spleen (Serratuls coronate var. insularis Kitamura) is known to be used as a food and medicinal plant in the Republic of Komi (Russia). The two main compounds contained in the acid spleen are the ecdysteroid family of 20-hydroxyecdysone and 25S inokosterone, anti-inflammation and anti-sedation. It is known to exhibit activity such as anti-sedation). In the present invention, when the acid spleen extract is further included, it has an excellent sleep-inducing effect.

The Sanbijang extract can be extracted in the same manner as the leather tree extract using at least one of the roots and leaves of the Sanbijang, and considering its efficacy, it is preferable to be included in 1 to 5% by weight in the health supplement food. Do.

Hereinafter, a method of manufacturing a health supplement food according to the present invention will be described in detail. Hereinafter, in describing the manufacturing method, the contents described in the health supplement food are omitted in order to avoid redundancy.

The method of manufacturing a health supplement according to the present invention includes the steps of mixing cherry concentrate and black ginseng concentrate, adding fish collagen peptide and a thickener to the mixed mixture, and filtering the mixed mixture. , Including the step of sterilizing the filtered mixture, the amount of each material is 8-12% by weight of black ginseng concentrate, 3-7% by weight of fish collagen peptide, 1-5% by weight of thickener, and the balance of cherry concentrate. It is characterized.

More specifically, the liquid raw material cherry concentrate and black ginseng concentrate are mixed. Then, fish collagen peptides and thickeners, which are powder materials, are added to the mixture, and then mixed for 60 to 120 minutes using a mixing machine.

Next, after filtering the mixed mixture using a microfiltration filter (MF: Micro Filtration, 0.01 to 10 μm of fluid), it is sterilized in a high-temperature sterilization system, that is, 93±1° C. for 10 to 20 seconds.

Then, while maintaining the sterilization temperature, the sterilized sterilization material is filled in the inner packaging material, sealed, and cooled to manufacture.

At this time, when the leather sprout extract, echinacea extract, or sanbijang extract is further added, it is added and mixed during the mixing process of the powdered material.

Hereinafter, the present invention will be described in detail through examples.

(Example 1)

The tart cherries were juiced to prepare a juice solution, which was concentrated under reduced pressure at 60° C. to prepare a cherry concentrate (solid content 60%).

Six-year-old red ginseng was steamed at 90°C for 100 minutes and dried at 40°C for 2 hours. This process was repeated 9 times to prepare black ginseng. Then, 5 weight times of purified water at 80°C was added to the prepared black ginseng, extracted for 10 hours at 90°C, and concentrated under reduced pressure at 60°C to prepare a black ginseng concentrate (68brix). The content of ginsenoids Rg1, Rg2, and Rg3 in the prepared black ginseng concentrate was 7mg/g.

Purified water was added to fish collagen in an amount of 4 weight times, and pepsin was added in an amount of 0.5% (w/w), hydrolyzed at 55° C. for 20 hours, and spray-dried to obtain fish collagen peptides having a molecular weight of 200 to 1,000 Da. Was prepared.

And after mixing 82% by weight of the cherry concentrate and 10% by weight of the black ginseng concentrate, 5% by weight of fish collagen peptide and 3% by weight of xanthan gum as a thickener were further added, stirred at 800 rpm for 1 hour, and filtered through a microfiltration filter. . Next, it was sterilized at 93°C for 15 seconds with a high-temperature sterilization system machine, filled in an inner packaging paper, and cooled after packaging.

(Example 2)

Conducted in the same manner as in Example 1, but after mixing 76% by weight of cherry concentrate and 10% by weight of black ginseng concentrate, 5% by weight of fish collagen peptide, 3% by weight of xanthan gum as a thickener, 2% by weight of leather tree extract, and echinacea extract 2% by weight and 2% by weight of the acid spleen extract were further mixed.

At this time, the leather tree extract is the leaves of the leather tree, the echinacea extract is the outpost of Echinacea angustifolia , and the mountain spleen extract is the root of the mountain spleen. Hot water extraction was performed at ~100°C for 5 hours. After extraction, it was filtered through Whatman No. 2 filter paper, filtered once more with a 0.45 μm filter, and then freeze-dried to prepare.

(Test Example 1)

The antioxidant activity of Example 1 was measured.

Antioxidant activity (electron donation ability, EDA%) of the sample was measured by modifying the method of Blois. 0.5 mL of 0.2 mM DPPH (1,1-diphenyl-2-picryl hydrazyl) was added to 2 mL of the sample and stirred for 30 minutes. After standing, the absorbance was measured at 517 nm. The electron donating effect was expressed by the rate of decrease in absorbance between the addition and no addition of the sample solution. And the radical scavenging activity was calculated by the following equation, and the results are shown in Table 1 below. BHT (synthetic antioxidant) was used as a control.

Radical scavenging activity (%) = (1-absorbance of sample added/absorbance of no additive) × 100

Test Example 1 result division Soaking activity (%) Example 1 54.5±0.5 Control 52.7±0.6

As shown in Table 1, according to the DPPH radical scavenging activity measurement result, it was confirmed that Example 1 of the present invention has excellent antioxidant activity.

(Test Example 2)

The anti-inflammatory activity of the sample of Example 1 was measured. At this time, the sample was lyophilized and used.

Inflammatory factors include Nitrite (or oxygen monoxide), IL-1β (interleukin-1beta), IL-6 (interleukin-6, interleukin-6), and TNF-α (tumor necrosis factor-alpha, or tumor necrosis factor-alpha) was used.

In the test method, inflammation was induced by using LPS (lipopolysaccharide) in macrophages, and it was investigated whether general inflammatory indicators when treated with the sample were suppressed. As a positive control, DEX (Dexamethasone) was used as a comparative drug.

And the results are shown in FIGS. 1 to 4.

As can be seen in FIGS. 1 to 4, when inflammation was induced with LPS, Nitrite increased significantly, but it was confirmed that Nitrite increased by the treatment of the sample decreased. As can be seen in FIGS. 2, 3 and 4 , When inducing inflammation due to LPS, cytokine was significantly increased, but it was confirmed that the inflammation was alleviated by treatment of the sample.

Accordingly, it was determined that Example 1 of the present invention has an inhibitory effect on inflammatory factors, and has an inhibitory effect at a level similar to that of DEX, which is known as an anti-inflammatory component.

(Test Example 3)

The effect of improving hypertension of the health supplements prepared according to Examples 1 and 2 was tested.

Ten adult men and women with hypertension were selected, the subjects were divided into two groups, and blood pressure was measured. And one group was to take the dietary supplement of Example 1 1 packet (20g) a day for 6 months, and the other group took the dietary supplement of Example 2 1 packet (20g) a day for 6 months. I made it. And after 6 months, the blood pressure of the subjects was measured. At this time, the blood pressure was measured at the same time as before the experiment. The results are shown in Table 2 below.

Test Example 3 result division Before the test After the test Systolic blood pressure Diastolic blood pressure Systolic blood pressure Diastolic blood pressure Example 1 One 140 92 130 77 2 143 93 131 79 3 145 96 135 80 4 150 94 134 79 5 149 91 132 77 Example 2 6 146 91 124 70 7 151 95 125 72 8 144 91 121 71 9 140 94 121 70 10 152 92 128 73

As shown in Table 2, it was confirmed that blood pressure was significantly improved in both groups ingesting the health supplements of Examples 1 and 2.

(Test Example 4)

In order to check the sleep induction performance of the health supplements of Examples 1 and 2, 20 adults complaining of insomnia were selected and divided into two groups, and one group of Example 1 was taken daily for one week. Another group was given Example 2 to take 1 packet (20g) daily for 1 week, and then the degree of improvement in sleep quality was evaluated by a 5-point score method (5: very good, 4: good, 3: average) Is, 2: bad, 1: very bad), and the average is shown in Table 3 below. Here, the quality of sleep was evaluated by: ① whether you fall asleep normally, ② whether you sleep without waking up at night, and ③ whether you feel tired when you wake up in the morning. As a control, only cherry concentrate was used, and 10 adults complaining of insomnia were selected in the same manner as in Examples 1 and 2 to take 1 packet (20 g) daily for 1 week.

Test Example 4 Results division Example 1 Example 2 Control Sleep quality 3.8 4.2 3.1

As shown in Table 3, it was confirmed that Examples 1 and 2 of the present invention received excellent evaluations in terms of the extent to which they take a good night's sleep without waking up at night and whether they feel tired when they wake up from bed in the morning.

As described above, specific parts of the present invention have been described in detail, and it is clear that these specific techniques are only preferred embodiments for those of ordinary skill in the art, and the scope of the present invention is not limited thereto. Accordingly, it will be said that the substantial scope of the present invention is defined by the appended claims and their equivalents.

Claims (5)

Black ginseng concentrate 8-12% by weight, fish collagen peptide 3-7% by weight, leather tree extract 1-5% by weight, echinacea extract 1-5% by weight, mountain spleen extract 1-5% by weight, thickener 1-5% % And the balance of cherry concentrate,
The black ginseng concentrate is obtained by adding water to black ginseng, extracting for 5 to 24 hours at 70 to 100°C, and concentrating under reduced pressure,
The fish collagen peptide is obtained by hydrolysis reaction by adding an enzyme to fish collagen, and has an average molecular weight of 200 Da to 1,000 Da,
The cherry concentrate is obtained by juicing cherries and concentrating under reduced pressure,
The leather tree extract, echinacea extract and mountain spleen extract,
Health supplement, characterized in that each sample is extracted using one or more of water and alcohol having 1 to 4 carbon atoms as a solvent.
delete delete Mixing the cherry concentrate and black ginseng concentrate,
Mixing by adding fish collagen peptide, leather tree extract, echinacea extract, mountain spleen extract and a thickener to the mixed solution,
Filtering the mixed mixture,
Including the step of sterilizing the filtered mixture at 92 ~ 94 ℃,
The mixing amount of each material is,
The black ginseng concentrate 8 to 12% by weight, fish collagen peptide 3 to 7% by weight, leather tree extract 1 to 5% by weight, echinacea extract 1 to 5% by weight, mountain spleen extract 1 to 5% by weight, thickener 1 to 5 % By weight and the balance of cherry concentrate,
The black ginseng concentrate is obtained by adding water to black ginseng, extracting for 5 to 24 hours at 70 to 100°C, and concentrating under reduced pressure,
The fish collagen peptide is obtained by hydrolysis reaction by adding an enzyme to fish collagen, and has an average molecular weight of 200 Da to 1,000 Da,
The cherry concentrate is juiced and concentrated under reduced pressure,
The leather tree extract, echinacea extract and mountain spleen extract,
A method for producing a health supplement, characterized in that each sample is extracted by using one or more of water and alcohol having 1 to 4 carbon atoms as a solvent.
delete

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