JPS6422816A - Production of microcapsule - Google Patents
Production of microcapsuleInfo
- Publication number
- JPS6422816A JPS6422816A JP62176751A JP17675187A JPS6422816A JP S6422816 A JPS6422816 A JP S6422816A JP 62176751 A JP62176751 A JP 62176751A JP 17675187 A JP17675187 A JP 17675187A JP S6422816 A JPS6422816 A JP S6422816A
- Authority
- JP
- Japan
- Prior art keywords
- water
- acetate
- dispersion
- drug particles
- diethyl acetate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicinal Preparation (AREA)
Abstract
PURPOSE:To readily obtain microcapsules of drug particles having the surface coated with polyvinyl acetate diethyl acetate, by dissolving the polyvinyl acetal diethyl acetate in cooled water, etc., dispersing the drug particles into the solution, gradually raising temperature and maintaining the dispersion at a specific temperature. CONSTITUTION:Polyvinyl acetate diethyl acetate is dissolved in water or slightly freezing aqueous solution cooled at -10-10 deg.C, preferably -5-5 deg.C. Then particles of water-insoluble or slightly water-soluble drugs such as erythromycin are dispersed into the solution, temperature of the dispersion is gradually raised and the dispersion is kept at 20-80 deg.C so that the surface of the drug particles is coated with a coating film of the polyvinyl acetate diethyl acetate to give microcapsules by a simple method and readily. Since neither organic solvent nor acidic aqueous solution is used in this method, no environmental pollution occurs, there is no fear of explosion by ignition and of inhalation of organic solvent vapor, the method is safe, neither decomposition of the drug for deterioration of coating film of capsules are brought about.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62176751A JPS6422816A (en) | 1987-07-15 | 1987-07-15 | Production of microcapsule |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62176751A JPS6422816A (en) | 1987-07-15 | 1987-07-15 | Production of microcapsule |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS6422816A true JPS6422816A (en) | 1989-01-25 |
Family
ID=16019171
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62176751A Pending JPS6422816A (en) | 1987-07-15 | 1987-07-15 | Production of microcapsule |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6422816A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01130730A (en) * | 1987-11-18 | 1989-05-23 | Showa Denko Kk | Dehydration equipment that controls water absorption |
| US5116661A (en) * | 1990-07-10 | 1992-05-26 | Showa Denko K.K. | Drip-absorbing sheet |
-
1987
- 1987-07-15 JP JP62176751A patent/JPS6422816A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01130730A (en) * | 1987-11-18 | 1989-05-23 | Showa Denko Kk | Dehydration equipment that controls water absorption |
| US5116661A (en) * | 1990-07-10 | 1992-05-26 | Showa Denko K.K. | Drip-absorbing sheet |
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