JPS60135066A - Drainage system - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

[Detailed Description of the Invention] [Technical Field] The present invention relates to donor ference dysplasia, in which only plasma is collected using a membrane plasma divider and blood cell components are returned to the blood donor when blood is collected from blood donation. It is something.

<Prior art> Centrifugation is one of the donor pheresis systems, but it is uneconomical because it requires expensive equipment, and sedimentation using inexpensive equipment requires a long time before plasma separation. The method using a membrane plasma separator is the most practical since the separated plasma does not contain formed components such as platelets, but it has the drawback of being slightly less economical.

<Objective> The object of the present invention is to provide a membrane separation type donor pheresis system which is highly economical.

<Example> An example of the present invention will be described based on the drawings. The drawing shows the flow path system of the system of the present invention, in which 1 is an extracorporeal blood circulation line, 2 is an anticoagulant line, 3 is a plasma line, 4 is a fluid replacement line, 5 and 6 are first and second lines, respectively. second 2
7 is a membrane plasma separator, 8.9 is an air trap, 1 (l is an anticoagulant container, 11 is a plasma storage tank, 12 is a
13 is a heater, and 14 is a transmembrane pressure controller.

Next, the operation will be explained.

The blood 7f& from the vein of the blood donor is circulated through the extracorporeal blood circulation line 1 by the operation of the first double pump 5 and returned to another vein, and by the operation of the pump 5, the blood 7f& is returned to the other vein.
0, an anticoagulant is added into the bloodstream at a specified ratio via an anticoagulant line 2 communicating with another line 1 of the pump 5, and the blood flow rate is 20 to 6011117 minutes. It is empirically preferred that the anti-coagulant flow rate ratio is about 9:1, and this ratio means that two elastic tubes with the same wall thickness and a flow passage cross-sectional area of 9:1 are connected to the first double roller. Pump 5 may be equipped as shown and communicated with blood line 1 and anticoagulant line 2, respectively.

The anticoagulated blood is defoamed by an air trap 8 and then supplied to a membrane plasma separator 7, and the plasma separated through the membrane in the separator is operated by a second double roller pump 6. The membrane plasma separator is preferably a hollow fiber type that uses cellulose triacetate as a small and highly efficient membrane material. Using bags is economical and convenient to handle.

Normally saline is added to the concentrated blood from the membrane plasma separator as a replacement fluid from a container 12 via a replacement fluid line 4 communicating with another route of the second dual roller pump 6;
The blood donor is heated to near the body temperature by the heater 13 to reduce the burden on the blood donor, but it is generally preferable that the flow rate ratio of plasma and replacement fluid be approximately 1:1 using the same means as the first dual roller pump. The flow rate ratio can be set to a specified value.

In order to prevent hemolysis due to excessive transmembrane pressure in the membrane plasma separator and to control plasma flow rate, plasma collection is performed as described below.
1: A control a1+ device 14 is arranged, and calculates the respective pressures from the air torso 18 on the flow side to the separator 7 and the plasma line connected to the dispenser to a transmembrane pressure, and converts the transmembrane pressure into a second transmembrane pressure. It is controlled by the rotation of the double roller pump 0.

<Effects> Since the present invention effectively arranges the double roach pump as described in the claims, the mechanism is simplified and it is also excellent in economical efficiency.

[Brief explanation of drawings]

The drawing shows a flow path system according to an embodiment of the present invention.
and 6 are double roller pumps, respectively, and 7 is a membrane separator. Patent applicant Nilasho Co., Ltd.

Claims (1)

[Claims] ■ In an extracorporeal blood circulation line in which blood from a vein is returned to the vein via a membrane plasma separator by a first double roller pump, an anticoagulant is applied at a specified ratio to the blood flow. The plasma is added to the bloodstream via another route of the dual roller pump, and the plasma is separated from the anticoagulated blood by the membrane of the membrane plasma separator 11, and the plasma is added to the bloodstream by the second dual roller pump. At the same time, it is supplied to the plasma storage tank, and is added to the blood flowing out from the plasma separator via the other loop 1 of the second dual roller pump, and then returned to the vein. 1. A donor pheresis system, wherein a transmembrane pressure of a membrane blood drug separator is controlled by rotation of a second dual roller pump. ■ The donor according to claim 1, wherein each of the two lines attached to the first and second double roller pumps is an elastic tube having an inner diameter of a prescribed ratio and the same wall thickness. pheresis system.