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JPS5811428B2 - インシユリンケイカゴウブツノセイホウ - Google Patents

インシユリンケイカゴウブツノセイホウ

Info

Publication number
JPS5811428B2
JPS5811428B2 JP50098657A JP9865775A JPS5811428B2 JP S5811428 B2 JPS5811428 B2 JP S5811428B2 JP 50098657 A JP50098657 A JP 50098657A JP 9865775 A JP9865775 A JP 9865775A JP S5811428 B2 JPS5811428 B2 JP S5811428B2
Authority
JP
Japan
Prior art keywords
insulin
chain
residue
general formula
acetic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP50098657A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5148661A (en
Inventor
ライナー・オーベルマイヤー
ロルフ・ガイガー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of JPS5148661A publication Critical patent/JPS5148661A/ja
Publication of JPS5811428B2 publication Critical patent/JPS5811428B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP50098657A 1974-08-16 1975-08-15 インシユリンケイカゴウブツノセイホウ Expired JPS5811428B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2439296A DE2439296A1 (de) 1974-08-16 1974-08-16 Verfahren zur herstellung von insulin, insulin-analogen und -derivaten

Publications (2)

Publication Number Publication Date
JPS5148661A JPS5148661A (en) 1976-04-26
JPS5811428B2 true JPS5811428B2 (ja) 1983-03-02

Family

ID=5923333

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50098657A Expired JPS5811428B2 (ja) 1974-08-16 1975-08-15 インシユリンケイカゴウブツノセイホウ

Country Status (12)

Country Link
US (1) US4013628A (da)
JP (1) JPS5811428B2 (da)
AU (1) AU8397675A (da)
BE (1) BE832521A (da)
CH (1) CH616651A5 (da)
DE (1) DE2439296A1 (da)
DK (1) DK370875A (da)
FR (1) FR2283124A1 (da)
GB (1) GB1519026A (da)
IL (1) IL47920A0 (da)
LU (1) LU73207A1 (da)
NL (1) NL7509541A (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2901297A1 (de) * 1979-01-13 1980-07-31 Hoechst Ag Neue sulfonierte insuline
JPS5962145A (ja) * 1982-10-02 1984-04-09 ロンシール工業株式会社 装飾シ−トの製造方法
US5646242A (en) * 1994-11-17 1997-07-08 Eli Lilly And Company Selective acylation of epsilon-amino groups
US5631347A (en) * 1995-06-07 1997-05-20 Eli Lilly And Company Reducing gelation of a fatty acid-acylated protein
US5700904A (en) * 1995-06-07 1997-12-23 Eli Lilly And Company Preparation of an acylated protein powder
US6323311B1 (en) 1999-09-22 2001-11-27 University Of Utah Research Foundation Synthesis of insulin derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3907763A (en) * 1972-03-01 1975-09-23 Bayer Ag Insulin derivatives crosslinked by a dicarboxylic acid moiety
US3847893A (en) * 1972-03-01 1974-11-12 Bayer Ag Process for the preparation of insulin derivatives cross-linked by a dicarboxylic acid group at the amino a-1 glycine and amino b-29 lysine
DE2252157C3 (de) * 1972-10-25 1976-03-18 Hoechst Ag Zwischenprodukte zur herstellung von insulin, insulin-analogen und -derivaten und verfahren zur herstellung von insulin, insulin analogen und derivaten
DE2253327A1 (de) * 1972-10-31 1974-05-09 Hoechst Ag Verfahren zur herstellung von insulin, insulin-analogen und -derivaten
NL7314766A (da) * 1972-10-31 1974-05-02

Also Published As

Publication number Publication date
LU73207A1 (da) 1977-04-13
DK370875A (da) 1976-02-17
BE832521A (fr) 1976-02-18
GB1519026A (en) 1978-07-26
CH616651A5 (da) 1980-04-15
JPS5148661A (en) 1976-04-26
FR2283124A1 (fr) 1976-03-26
US4013628A (en) 1977-03-22
DE2439296A1 (de) 1976-02-26
AU8397675A (en) 1977-02-17
FR2283124B1 (da) 1978-09-22
IL47920A0 (en) 1975-11-25
NL7509541A (nl) 1976-02-18

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