JPS5770824A - Vehicle for medicine - Google Patents
Vehicle for medicineInfo
- Publication number
- JPS5770824A JPS5770824A JP14649680A JP14649680A JPS5770824A JP S5770824 A JPS5770824 A JP S5770824A JP 14649680 A JP14649680 A JP 14649680A JP 14649680 A JP14649680 A JP 14649680A JP S5770824 A JPS5770824 A JP S5770824A
- Authority
- JP
- Japan
- Prior art keywords
- active agent
- vehicle
- water
- oily substance
- polyhydric alcohol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicinal Preparation (AREA)
Abstract
PURPOSE: To provide a vehicle for medicine, having excellent stability, feeling to the skin, washability with water, dispersability in water, solubility in the drug component, etc., and composed of an ethylene oxide addition-type hydrophilic nonionic surface-active agent having an HLB of ≥12, a polyhydric alcohol, and an oily substance.
CONSTITUTION: An ethylene oxide addition-type hydrophilic nonionic surface-active agent having an HLB value of ≥12 (e.g. poloxyethylene hardened castor oil) is mixed homogeneously with a polyhydric alcohol having two or more hydroxyl groups in the molecule (e.g. propylene glycol), and an oily substance (e.g. a mineral oil) is added to the mixture to obtain the objective vehicle. The weight ratio of the surface active agent to the alcohol is 1 to 20W2, and that of the surface active agent to the oily substance is ≥1 to 20. The vehicle may be incorporated with a water- soluble polymer soluble in the polyhydric alcohol (e.g. PVA) and inorganic powder (e.g. silicic anhydride) to improve the visco-elasticity of the product, or ≤15wt% of an oil-soluble surface-active agent to adjust the HLB value.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14649680A JPS5770824A (en) | 1980-10-20 | 1980-10-20 | Vehicle for medicine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14649680A JPS5770824A (en) | 1980-10-20 | 1980-10-20 | Vehicle for medicine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5770824A true JPS5770824A (en) | 1982-05-01 |
Family
ID=15408932
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP14649680A Pending JPS5770824A (en) | 1980-10-20 | 1980-10-20 | Vehicle for medicine |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5770824A (en) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5933211A (en) * | 1982-08-20 | 1984-02-23 | Sato Seiyaku Kk | Oleaginous ointment |
| JPS61176522A (en) * | 1982-08-27 | 1986-08-08 | ケネス・エル・エベンスタツド | Suppository for lubrication |
| US4767625A (en) * | 1985-09-02 | 1988-08-30 | Kao Corporation | Lamella type single phase liquid crystal composition and oil-base cosmetic compositions using the same |
| EP0338081A1 (en) * | 1987-09-25 | 1989-10-25 | Fujisawa Pharmaceutical Co., Ltd. | Oily rectal instillation |
| WO1994023688A2 (en) * | 1993-04-19 | 1994-10-27 | Beiersdorf Ag | Cosmetic and medicinal topical preparations |
| JP2012116863A (en) * | 1999-11-23 | 2012-06-21 | Lipocine Inc | Solid carrier for better delivery of active ingredient in pharmaceutical composition |
| US9757389B2 (en) | 2014-08-28 | 2017-09-12 | Lipocine Inc. | Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters |
| US9757390B2 (en) | 2010-11-30 | 2017-09-12 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US10561615B2 (en) | 2010-12-10 | 2020-02-18 | Lipocine Inc. | Testosterone undecanoate compositions |
| US11433083B2 (en) | 2010-11-30 | 2022-09-06 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US11559530B2 (en) | 2016-11-28 | 2023-01-24 | Lipocine Inc. | Oral testosterone undecanoate therapy |
| US11707467B2 (en) | 2014-08-28 | 2023-07-25 | Lipocine Inc. | (17-ß)-3-oxoandrost-4-en-17YL tridecanoate compositions and methods of their preparation and use |
-
1980
- 1980-10-20 JP JP14649680A patent/JPS5770824A/en active Pending
Cited By (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5933211A (en) * | 1982-08-20 | 1984-02-23 | Sato Seiyaku Kk | Oleaginous ointment |
| JPS61176522A (en) * | 1982-08-27 | 1986-08-08 | ケネス・エル・エベンスタツド | Suppository for lubrication |
| US4767625A (en) * | 1985-09-02 | 1988-08-30 | Kao Corporation | Lamella type single phase liquid crystal composition and oil-base cosmetic compositions using the same |
| EP0338081A1 (en) * | 1987-09-25 | 1989-10-25 | Fujisawa Pharmaceutical Co., Ltd. | Oily rectal instillation |
| EP0338081A4 (en) * | 1987-09-25 | 1990-12-19 | Fujisawa Pharmaceutical Co., Ltd. | Oily rectal instillation |
| WO1994023688A2 (en) * | 1993-04-19 | 1994-10-27 | Beiersdorf Ag | Cosmetic and medicinal topical preparations |
| WO1994023688A3 (en) * | 1993-04-19 | 1995-01-19 | Beiersdorf Ag | Cosmetic and medicinal topical preparations |
| JP2012116863A (en) * | 1999-11-23 | 2012-06-21 | Lipocine Inc | Solid carrier for better delivery of active ingredient in pharmaceutical composition |
| US10226473B2 (en) | 2010-11-30 | 2019-03-12 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US11364249B2 (en) | 2010-11-30 | 2022-06-21 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US9943527B2 (en) | 2010-11-30 | 2018-04-17 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US9949985B2 (en) | 2010-11-30 | 2018-04-24 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US11433083B2 (en) | 2010-11-30 | 2022-09-06 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US9757390B2 (en) | 2010-11-30 | 2017-09-12 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US10716794B2 (en) | 2010-11-30 | 2020-07-21 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US10799513B2 (en) | 2010-11-30 | 2020-10-13 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US10881671B2 (en) | 2010-11-30 | 2021-01-05 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US10973833B2 (en) | 2010-11-30 | 2021-04-13 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US11364250B2 (en) | 2010-11-30 | 2022-06-21 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US11311555B2 (en) | 2010-11-30 | 2022-04-26 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US10561615B2 (en) | 2010-12-10 | 2020-02-18 | Lipocine Inc. | Testosterone undecanoate compositions |
| US11298365B2 (en) | 2014-08-28 | 2022-04-12 | Lipocine Inc. | Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters |
| US9757389B2 (en) | 2014-08-28 | 2017-09-12 | Lipocine Inc. | Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters |
| US11707467B2 (en) | 2014-08-28 | 2023-07-25 | Lipocine Inc. | (17-ß)-3-oxoandrost-4-en-17YL tridecanoate compositions and methods of their preparation and use |
| US11872235B1 (en) | 2014-08-28 | 2024-01-16 | Lipocine Inc. | Bioavailable solid state (17-β)-Hydroxy-4-Androsten-3-one esters |
| US12171770B1 (en) | 2014-08-28 | 2024-12-24 | Lipocine Inc. | Bioavailable solid state (17-beta)-hydroxy-4-androsten-3-one esters |
| US11559530B2 (en) | 2016-11-28 | 2023-01-24 | Lipocine Inc. | Oral testosterone undecanoate therapy |
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