JPS57206611A - Production of stabilized dimethylpolysiloxane solution for internal use - Google Patents
Production of stabilized dimethylpolysiloxane solution for internal useInfo
- Publication number
- JPS57206611A JPS57206611A JP56090977A JP9097781A JPS57206611A JP S57206611 A JPS57206611 A JP S57206611A JP 56090977 A JP56090977 A JP 56090977A JP 9097781 A JP9097781 A JP 9097781A JP S57206611 A JPS57206611 A JP S57206611A
- Authority
- JP
- Japan
- Prior art keywords
- solution
- surface active
- active agent
- antioxidant
- internal use
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 235000013870 dimethyl polysiloxane Nutrition 0.000 title abstract 3
- 239000004205 dimethyl polysiloxane Substances 0.000 title abstract 3
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 title abstract 3
- 239000004094 surface-active agent Substances 0.000 abstract 4
- 239000003963 antioxidant agent Substances 0.000 abstract 3
- 230000003078 antioxidant effect Effects 0.000 abstract 3
- 239000002562 thickening agent Substances 0.000 abstract 3
- -1 Dimethylsiloxane Chemical class 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- SPSPIUSUWPLVKD-UHFFFAOYSA-N 2,3-dibutyl-6-methylphenol Chemical compound CCCCC1=CC=C(C)C(O)=C1CCCC SPSPIUSUWPLVKD-UHFFFAOYSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 abstract 1
- 235000010354 butylated hydroxytoluene Nutrition 0.000 abstract 1
- 229920003123 carboxymethyl cellulose sodium Polymers 0.000 abstract 1
- 229940063834 carboxymethylcellulose sodium Drugs 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000000600 sorbitol Substances 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: A surface active agent, a thickening agent and an antioxidant are added to dimethylpolysiloxane to produce a solution for internal use with remarkably increased stability, scarce formation of strange odor even on the long-term storage and activity of defoaming or removing foamed sticky solution.
CONSTITUTION: Dimethylsiloxane of the formula (n is 80W360) is combined with a surface active agent, a thickening agent and an antioxidant to give the objectie solution for internal use. The resulatant solution is almost free from the formation of strange odor and the increase in particles sizes of the oily components, when it is stored for a long period of time or under relatively high temperature and always shows constant effects. As a surface active agent, are used 30W60pts.wt. per 100pts. of dimethylpolysiloxane, of polyoxyethylene sorbitol monoleate, as a thickening agent, 20W100pts. of carboxymethylcellulose sodium and as an antioxidant, 0.001W2.0pts., per 100pts. of the surface active agent, of dibutylhydroxytoluene.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56090977A JPS57206611A (en) | 1981-06-15 | 1981-06-15 | Production of stabilized dimethylpolysiloxane solution for internal use |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56090977A JPS57206611A (en) | 1981-06-15 | 1981-06-15 | Production of stabilized dimethylpolysiloxane solution for internal use |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57206611A true JPS57206611A (en) | 1982-12-18 |
JPH0314813B2 JPH0314813B2 (en) | 1991-02-27 |
Family
ID=14013573
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56090977A Granted JPS57206611A (en) | 1981-06-15 | 1981-06-15 | Production of stabilized dimethylpolysiloxane solution for internal use |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57206611A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5420176A (en) * | 1990-06-01 | 1995-05-30 | Imarx Pharmaceutical Corp. | Contrast media for ultrasonic imaging |
WO1997036600A1 (en) * | 1996-03-29 | 1997-10-09 | Ambi Inc. | Polysorbate-containing compositions and their use against helicobacter |
US5948387A (en) * | 1990-06-01 | 1999-09-07 | Imarx Pharmaceutical Corp. | Contrast media for ultrasonic imaging |
CN102048690A (en) * | 2011-01-14 | 2011-05-11 | 四川健能制药有限公司 | Dimeticone emulsion and preparation method thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5136325A (en) * | 1974-06-08 | 1976-03-27 | Chizuru Watanabe | JITENSHASOKORENSHUSOCHI |
JPS5155783A (en) * | 1974-11-12 | 1976-05-17 | Shiseido Co Ltd |
-
1981
- 1981-06-15 JP JP56090977A patent/JPS57206611A/en active Granted
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5136325A (en) * | 1974-06-08 | 1976-03-27 | Chizuru Watanabe | JITENSHASOKORENSHUSOCHI |
JPS5155783A (en) * | 1974-11-12 | 1976-05-17 | Shiseido Co Ltd |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5420176A (en) * | 1990-06-01 | 1995-05-30 | Imarx Pharmaceutical Corp. | Contrast media for ultrasonic imaging |
US5639442A (en) * | 1990-06-01 | 1997-06-17 | Imarx Pharmaceutical Corp. | Contrast media for ultrasonic imaging |
US5714529A (en) * | 1990-06-01 | 1998-02-03 | Imarx Pharmaceutical Corp. | Contrast media for ultrasonic imaging |
US5714528A (en) * | 1990-06-01 | 1998-02-03 | Imarx Pharmaceutical Corp. | Contrast media for ultrasonic imaging |
US5948387A (en) * | 1990-06-01 | 1999-09-07 | Imarx Pharmaceutical Corp. | Contrast media for ultrasonic imaging |
US6024939A (en) * | 1990-06-01 | 2000-02-15 | Imarx Pharmaceutical Corp. | Contrast media for ultrasonic imaging |
WO1997036600A1 (en) * | 1996-03-29 | 1997-10-09 | Ambi Inc. | Polysorbate-containing compositions and their use against helicobacter |
CN102048690A (en) * | 2011-01-14 | 2011-05-11 | 四川健能制药有限公司 | Dimeticone emulsion and preparation method thereof |
Also Published As
Publication number | Publication date |
---|---|
JPH0314813B2 (en) | 1991-02-27 |
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