JPS57144269A - Triazine derivative and its preparation - Google Patents
Triazine derivative and its preparationInfo
- Publication number
- JPS57144269A JPS57144269A JP3076981A JP3076981A JPS57144269A JP S57144269 A JPS57144269 A JP S57144269A JP 3076981 A JP3076981 A JP 3076981A JP 3076981 A JP3076981 A JP 3076981A JP S57144269 A JPS57144269 A JP S57144269A
- Authority
- JP
- Japan
- Prior art keywords
- lower alkyl
- compound
- triazine derivative
- solvent
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000003918 triazines Chemical class 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 239000002904 solvent Substances 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000001741 anti-phlogistic effect Effects 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 229940030606 diuretics Drugs 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:The triazine derivative of formulaI(R1 is phenyl which may have halogen, lower alkyl or lower alkoxy as substituent; R2 is H or lower alkyl; R3 is lower alkyl; X is O or S). EXAMPLE4-Methylthio-1-phenyl-s-triazin-2(1H)-one.
USE: Diuretics, antibacterials, antiphlogistics, analgesics, etc.
PROCESS: The compound of formulaIis prepared by reacting the compound of formula II (Y is lower alkyl) with the compound of formula III (Z is same as Y) in a proper solvent or in the absence of solvent at a temperature between 50°C and the refluxing temperature of the solvent for 0.5W10hr.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3076981A JPS57144269A (en) | 1981-03-03 | 1981-03-03 | Triazine derivative and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3076981A JPS57144269A (en) | 1981-03-03 | 1981-03-03 | Triazine derivative and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS57144269A true JPS57144269A (en) | 1982-09-06 |
| JPH0159273B2 JPH0159273B2 (en) | 1989-12-15 |
Family
ID=12312881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3076981A Granted JPS57144269A (en) | 1981-03-03 | 1981-03-03 | Triazine derivative and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57144269A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010092966A1 (en) * | 2009-02-13 | 2010-08-19 | 塩野義製薬株式会社 | Novel triazine derivative and pharmaceutical composition containing same |
| JPWO2013147183A1 (en) * | 2012-03-30 | 2015-12-14 | 日産化学工業株式会社 | Triazinone compound and T-type calcium channel inhibitor |
| US9212130B2 (en) | 2010-08-10 | 2015-12-15 | Shionogi & Co., Ltd. | Heterocyclic derivative and pharmaceutical composition comprising the same |
| US9550763B2 (en) | 2012-02-09 | 2017-01-24 | Shionogi & Co., Ltd. | Heterocyclic ring and carbocyclic derivative |
| US9718790B2 (en) | 2010-08-10 | 2017-08-01 | Shionogi & Co., Ltd. | Triazine derivative and pharmaceutical composition having an analgesic activity comprising the same |
| US9732060B2 (en) | 2013-06-14 | 2017-08-15 | Shionogi & Co., Ltd. | Aminotriazine derivative and pharmaceutical composition comprising the same |
-
1981
- 1981-03-03 JP JP3076981A patent/JPS57144269A/en active Granted
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010092966A1 (en) * | 2009-02-13 | 2010-08-19 | 塩野義製薬株式会社 | Novel triazine derivative and pharmaceutical composition containing same |
| AU2010214356B2 (en) * | 2009-02-13 | 2014-10-30 | Shionogi & Co. Ltd. | Novel triazine derivative and pharmaceutical composition containing same |
| JP5692747B2 (en) * | 2009-02-13 | 2015-04-01 | 塩野義製薬株式会社 | Novel triazine derivative and pharmaceutical composition containing the same |
| US9150546B2 (en) | 2009-02-13 | 2015-10-06 | Shionogi & Co., Ltd. | Triazine derivative and pharmaceutical composition comprising the same |
| US9688643B2 (en) | 2009-02-13 | 2017-06-27 | Shionogi & Co., Ltd. | Triazine derivative and pharmaceutical composition comprising the same |
| US9212130B2 (en) | 2010-08-10 | 2015-12-15 | Shionogi & Co., Ltd. | Heterocyclic derivative and pharmaceutical composition comprising the same |
| US9718790B2 (en) | 2010-08-10 | 2017-08-01 | Shionogi & Co., Ltd. | Triazine derivative and pharmaceutical composition having an analgesic activity comprising the same |
| US9550763B2 (en) | 2012-02-09 | 2017-01-24 | Shionogi & Co., Ltd. | Heterocyclic ring and carbocyclic derivative |
| JPWO2013147183A1 (en) * | 2012-03-30 | 2015-12-14 | 日産化学工業株式会社 | Triazinone compound and T-type calcium channel inhibitor |
| US9732060B2 (en) | 2013-06-14 | 2017-08-15 | Shionogi & Co., Ltd. | Aminotriazine derivative and pharmaceutical composition comprising the same |
| US10065941B2 (en) | 2013-06-14 | 2018-09-04 | Shionogi & Co., Ltd. | Aminotriazine derivative and pharmaceutical composition comprising the same |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0159273B2 (en) | 1989-12-15 |
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