JPS57126451A - Preparation of 2-aminopropanol derivative - Google Patents
Preparation of 2-aminopropanol derivativeInfo
- Publication number
- JPS57126451A JPS57126451A JP56011957A JP1195781A JPS57126451A JP S57126451 A JPS57126451 A JP S57126451A JP 56011957 A JP56011957 A JP 56011957A JP 1195781 A JP1195781 A JP 1195781A JP S57126451 A JPS57126451 A JP S57126451A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- hydrochloric acid
- derivative
- pref
- platinum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
PURPOSE: To prepare the titled compound useful as a medicine for the circulatory organs, etx., economically and safely, by the catalytic reduction of a 2-hydroxyiminopropiophenone derivative in an organic solvent containing hydrochloric acid in the presence of a platinum-carbon catalyst.
CONSTITUTION: The 1-pheny1-2-aminopropanol derivative of formula II (X is methyl, methoxy, OH or halogen) is prepared by the catalytic reduction of the compound of formulaIin an organic solvent containing hydrochloric acid in the prosence of a platinum-carbon catalyst. The amount of hydrochloric acid is 1W6mol, pref. 2W5mol/1mol of the starting compound. The solvent is pref. methanol, ethanol, etc. Since hydrogen chloride gas is not used in the reaction, the objective compound can be obtained safely, in high selectivity, with little side reactions. The compound of formula II is also useful as a drug acting to the sympathetic nervous system.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56011957A JPS57126451A (en) | 1981-01-29 | 1981-01-29 | Preparation of 2-aminopropanol derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56011957A JPS57126451A (en) | 1981-01-29 | 1981-01-29 | Preparation of 2-aminopropanol derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57126451A true JPS57126451A (en) | 1982-08-06 |
Family
ID=11792091
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56011957A Pending JPS57126451A (en) | 1981-01-29 | 1981-01-29 | Preparation of 2-aminopropanol derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57126451A (en) |
-
1981
- 1981-01-29 JP JP56011957A patent/JPS57126451A/en active Pending
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