JPS56104816A - Preventive and remedy for caridac infarction - Google Patents
Preventive and remedy for caridac infarctionInfo
- Publication number
- JPS56104816A JPS56104816A JP690780A JP690780A JPS56104816A JP S56104816 A JPS56104816 A JP S56104816A JP 690780 A JP690780 A JP 690780A JP 690780 A JP690780 A JP 690780A JP S56104816 A JPS56104816 A JP S56104816A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- carboxyl
- trans
- ethyl ester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010061216 Infarction Diseases 0.000 title abstract 2
- 230000007574 infarction Effects 0.000 title abstract 2
- 230000003449 preventive effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 125000003440 L-leucyl group Chemical class O=C([*])[C@](N([H])[H])([H])C([H])([H])C(C([H])([H])[H])([H])C([H])([H])[H] 0.000 abstract 1
- 241000283973 Oryctolagus cuniculus Species 0.000 abstract 1
- 231100000215 acute (single dose) toxicity testing Toxicity 0.000 abstract 1
- 238000011047 acute toxicity test Methods 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- QIGLJVBIRIXQRN-ZETCQYMHSA-N ethyl (2s)-2-amino-4-methylpentanoate Chemical compound CCOC(=O)[C@@H](N)CC(C)C QIGLJVBIRIXQRN-ZETCQYMHSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- DCEMCPAKSGRHCN-JCYAYHJZSA-N trans-2,3-epoxysuccinic acid Chemical compound OC(=O)[C@@H]1O[C@H]1C(O)=O DCEMCPAKSGRHCN-JCYAYHJZSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP690780A JPS56104816A (en) | 1980-01-25 | 1980-01-25 | Preventive and remedy for caridac infarction |
| ES498734A ES498734A0 (es) | 1980-01-25 | 1981-01-22 | Procedimiento para la obtencion de un agente anti-infarto miocardio |
| BR8100350A BR8100350A (pt) | 1980-01-25 | 1981-01-23 | Processo para a obtencao de derivados do acido epoxisuccinio |
| FR8101330A FR2474497A1 (fr) | 1980-01-25 | 1981-01-23 | Derive d'acide epoxysuccinique, son procede de preparation et son application en therapeutique |
| GB8102291A GB2067999A (en) | 1980-01-25 | 1981-01-26 | Epoxysuccinic Acid Derivatives |
| IT19331/81A IT1141956B (it) | 1980-01-25 | 1981-01-26 | Derivato dell'acido epossisuccinico,procedimento per la sua preparazione ed agente contro l'infarto miocardico contenente tale derivato |
| DE19813102486 DE3102486A1 (de) | 1980-01-25 | 1981-01-26 | Epoxybernsteinsaeurederivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP690780A JPS56104816A (en) | 1980-01-25 | 1980-01-25 | Preventive and remedy for caridac infarction |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS56104816A true JPS56104816A (en) | 1981-08-20 |
| JPS6365644B2 JPS6365644B2 (pt) | 1988-12-16 |
Family
ID=11651300
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP690780A Granted JPS56104816A (en) | 1980-01-25 | 1980-01-25 | Preventive and remedy for caridac infarction |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS56104816A (pt) |
| BR (1) | BR8100350A (pt) |
| DE (1) | DE3102486A1 (pt) |
| ES (1) | ES498734A0 (pt) |
| FR (1) | FR2474497A1 (pt) |
| GB (1) | GB2067999A (pt) |
| IT (1) | IT1141956B (pt) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1595168A (en) * | 1977-03-03 | 1981-08-12 | Taisho Pharmaceutical Co Ltd | Expoxysuccinic acid derivatives |
-
1980
- 1980-01-25 JP JP690780A patent/JPS56104816A/ja active Granted
-
1981
- 1981-01-22 ES ES498734A patent/ES498734A0/es active Granted
- 1981-01-23 FR FR8101330A patent/FR2474497A1/fr active Pending
- 1981-01-23 BR BR8100350A patent/BR8100350A/pt unknown
- 1981-01-26 IT IT19331/81A patent/IT1141956B/it active
- 1981-01-26 DE DE19813102486 patent/DE3102486A1/de not_active Withdrawn
- 1981-01-26 GB GB8102291A patent/GB2067999A/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| BR8100350A (pt) | 1981-08-11 |
| IT1141956B (it) | 1986-10-08 |
| GB2067999A (en) | 1981-08-05 |
| ES8201567A1 (es) | 1982-01-01 |
| DE3102486A1 (de) | 1981-11-19 |
| IT8119331A0 (it) | 1981-01-26 |
| FR2474497A1 (fr) | 1981-07-31 |
| ES498734A0 (es) | 1982-01-01 |
| JPS6365644B2 (pt) | 1988-12-16 |
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