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JPS55105666A - Piperidine derivative - Google Patents

Piperidine derivative

Info

Publication number
JPS55105666A
JPS55105666A JP1411179A JP1411179A JPS55105666A JP S55105666 A JPS55105666 A JP S55105666A JP 1411179 A JP1411179 A JP 1411179A JP 1411179 A JP1411179 A JP 1411179A JP S55105666 A JPS55105666 A JP S55105666A
Authority
JP
Japan
Prior art keywords
benzyl
formula
benzoyl
compound shown
tetra
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1411179A
Other languages
Japanese (ja)
Other versions
JPS6156228B2 (en
Inventor
Hiroshi Murai
Shingo Matsumura
Yoshiaki Aoyanagi
Shoichi Jokai
Mitsuhiro Maehara
Masahiro Yagi
Ichiro Shirahase
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shinyaku Co Ltd
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Priority to JP1411179A priority Critical patent/JPS55105666A/en
Publication of JPS55105666A publication Critical patent/JPS55105666A/en
Publication of JPS6156228B2 publication Critical patent/JPS6156228B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A piperidine derivative shown by the formula I (R<1> is benzyl or benzoyl; R<2> is H or 1-3C lower alkyl) and its acid addition salt. EXAMPLE:A compound shown by the formula II (Bn is benzyl). USE:Useful as a starting material of moranoline, an N-lower alkylmoranoline, much available as a drug. PROCESS:For example, 2,3,4,6-tetra-O-benzyl (or benzoyl)-gamma-gluconic lactone is subjected to ammonolysis to give 2,3,4,6-tetra-O-benzyl (or benzoyl)-5-ketogluconic acid amide, which undergoes ring closure by an acidic catalyst to prepare a compound shown by the formula III. The compound is reduced by lithium aluminum hydride to give the desired compound shown by the formula I.
JP1411179A 1979-02-08 1979-02-08 Piperidine derivative Granted JPS55105666A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1411179A JPS55105666A (en) 1979-02-08 1979-02-08 Piperidine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1411179A JPS55105666A (en) 1979-02-08 1979-02-08 Piperidine derivative

Publications (2)

Publication Number Publication Date
JPS55105666A true JPS55105666A (en) 1980-08-13
JPS6156228B2 JPS6156228B2 (en) 1986-12-01

Family

ID=11851996

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1411179A Granted JPS55105666A (en) 1979-02-08 1979-02-08 Piperidine derivative

Country Status (1)

Country Link
JP (1) JPS55105666A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252587A (en) * 1990-04-27 1993-10-12 Merrell Dow Pharmaceuticals, Inc. N-derivatives of 1-deoxy nojirimycin
US5536732A (en) * 1990-04-27 1996-07-16 Merrell Pharmaceuticals Inc. N-derivatives of 1-deoxy nojirimycin
JP2008001711A (en) * 2000-03-31 2008-01-10 Univ Michigan State Preparation of 1,5-dideoxy-1,5-iminohexitol from oxime or imine

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252587A (en) * 1990-04-27 1993-10-12 Merrell Dow Pharmaceuticals, Inc. N-derivatives of 1-deoxy nojirimycin
US5536732A (en) * 1990-04-27 1996-07-16 Merrell Pharmaceuticals Inc. N-derivatives of 1-deoxy nojirimycin
JP2008001711A (en) * 2000-03-31 2008-01-10 Univ Michigan State Preparation of 1,5-dideoxy-1,5-iminohexitol from oxime or imine

Also Published As

Publication number Publication date
JPS6156228B2 (en) 1986-12-01

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