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JPS5295674A - Preparation of 4#-substituted-2-methyl-2-piperidinopropiophenone and i ts salts - Google Patents

Preparation of 4#-substituted-2-methyl-2-piperidinopropiophenone and i ts salts

Info

Publication number
JPS5295674A
JPS5295674A JP1220676A JP1220676A JPS5295674A JP S5295674 A JPS5295674 A JP S5295674A JP 1220676 A JP1220676 A JP 1220676A JP 1220676 A JP1220676 A JP 1220676A JP S5295674 A JPS5295674 A JP S5295674A
Authority
JP
Japan
Prior art keywords
substituted
methyl
piperidinopropiophenone
salts
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1220676A
Other languages
Japanese (ja)
Inventor
Yukio Yokoyama
Yoshikuni Tobiyo
Hitoshi Horikiri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Carbide Industries Co Inc
Original Assignee
Nippon Carbide Industries Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Carbide Industries Co Inc filed Critical Nippon Carbide Industries Co Inc
Priority to JP1220676A priority Critical patent/JPS5295674A/en
Publication of JPS5295674A publication Critical patent/JPS5295674A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: High purity 4'-substituted-2-methyl-3-piperdinopropiophenone, useful as sedative analgesic agents, is prepared in high yield by the reaction of 4'-substitutedpropiophenone, etc. in a specific solvent.
COPYRIGHT: (C)1977,JPO&Japio
JP1220676A 1976-02-09 1976-02-09 Preparation of 4#-substituted-2-methyl-2-piperidinopropiophenone and i ts salts Pending JPS5295674A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1220676A JPS5295674A (en) 1976-02-09 1976-02-09 Preparation of 4#-substituted-2-methyl-2-piperidinopropiophenone and i ts salts

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1220676A JPS5295674A (en) 1976-02-09 1976-02-09 Preparation of 4#-substituted-2-methyl-2-piperidinopropiophenone and i ts salts

Publications (1)

Publication Number Publication Date
JPS5295674A true JPS5295674A (en) 1977-08-11

Family

ID=11798903

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1220676A Pending JPS5295674A (en) 1976-02-09 1976-02-09 Preparation of 4#-substituted-2-methyl-2-piperidinopropiophenone and i ts salts

Country Status (1)

Country Link
JP (1) JPS5295674A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59190981A (en) * 1983-04-15 1984-10-29 Hokuriku Seiyaku Co Ltd 3-pyrrolidino-substituted propiophenone derivative
WO2004050648A1 (en) * 2002-12-05 2004-06-17 Sanochemia Pharmazeutika Ag Method for producing salts of tolperisone
CN107868065A (en) * 2017-10-19 2018-04-03 湖北美林药业有限公司 A kind of Flubuperone Hydrochloride compound and preparation method thereof
CN116253699A (en) * 2021-12-09 2023-06-13 广州白云山汉方现代药业有限公司 New crystal form of tolperisone hydrochloride and preparation method thereof

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59190981A (en) * 1983-04-15 1984-10-29 Hokuriku Seiyaku Co Ltd 3-pyrrolidino-substituted propiophenone derivative
WO2004050648A1 (en) * 2002-12-05 2004-06-17 Sanochemia Pharmazeutika Ag Method for producing salts of tolperisone
US7385060B2 (en) 2002-12-05 2008-06-10 Sanochemia Pharmazeutika Ag Method for producing salts of tolperisone
CN107868065A (en) * 2017-10-19 2018-04-03 湖北美林药业有限公司 A kind of Flubuperone Hydrochloride compound and preparation method thereof
CN107868065B (en) * 2017-10-19 2021-05-18 湖北美林药业有限公司 Tolperisone hydrochloride compound and preparation method thereof
CN116253699A (en) * 2021-12-09 2023-06-13 广州白云山汉方现代药业有限公司 New crystal form of tolperisone hydrochloride and preparation method thereof

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