JPS52111576A - Synthesis of 5,7,8-trimethyl-3,4-dehydrotocotrienol - Google Patents
Synthesis of 5,7,8-trimethyl-3,4-dehydrotocotrienolInfo
- Publication number
- JPS52111576A JPS52111576A JP2705976A JP2705976A JPS52111576A JP S52111576 A JPS52111576 A JP S52111576A JP 2705976 A JP2705976 A JP 2705976A JP 2705976 A JP2705976 A JP 2705976A JP S52111576 A JPS52111576 A JP S52111576A
- Authority
- JP
- Japan
- Prior art keywords
- dehydrotocotrienol
- trimethyl
- synthesis
- geranylgeranylbenzoquinone
- coveniently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
Landscapes
- Pyrane Compounds (AREA)
Abstract
PURPOSE: To coveniently prepare title compound useful as medical intermediate, physiologically active substance, and antioxydant by cyclization of the corresponding geranylgeranylbenzoquinone in the presence of a specific amine.
COPYRIGHT: (C)1977,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2705976A JPS52111576A (en) | 1976-03-15 | 1976-03-15 | Synthesis of 5,7,8-trimethyl-3,4-dehydrotocotrienol |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2705976A JPS52111576A (en) | 1976-03-15 | 1976-03-15 | Synthesis of 5,7,8-trimethyl-3,4-dehydrotocotrienol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS52111576A true JPS52111576A (en) | 1977-09-19 |
Family
ID=12210481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2705976A Pending JPS52111576A (en) | 1976-03-15 | 1976-03-15 | Synthesis of 5,7,8-trimethyl-3,4-dehydrotocotrienol |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS52111576A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2471530A1 (en) | 2005-06-01 | 2012-07-04 | Edison Pharmaceuticals, Inc. | Redox-active Therapeutics For Treatment Of Mitochondrial Diseases And Other Conditions And Modulation Of Energy Biomarkers |
| US9278085B2 (en) | 2006-02-22 | 2016-03-08 | Edison Pharmaceuticals, Inc. | Side-chain variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
| US10105325B2 (en) | 2008-09-10 | 2018-10-23 | Bioelectron Technology Corporation | Treatment of pervasive developmental disorders with redox-active therapeutics |
| US10703701B2 (en) | 2015-12-17 | 2020-07-07 | Ptc Therapeutics, Inc. | Fluoroalkyl, fluoroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders |
| CN117597335A (en) * | 2021-04-28 | 2024-02-23 | 帝斯曼知识产权资产管理有限公司 | Ring Closure of Benzoquinones Containing Unsaturated Side Chains Using Basic Catalysts |
-
1976
- 1976-03-15 JP JP2705976A patent/JPS52111576A/en active Pending
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11021424B2 (en) | 2005-06-01 | 2021-06-01 | Ptc Therapeutics, Inc. | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
| EP2564843A1 (en) | 2005-06-01 | 2013-03-06 | Edison Pharmaceuticals, Inc. | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
| EP2564842A1 (en) | 2005-06-01 | 2013-03-06 | Edison Pharmaceuticals, Inc. | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
| US9447006B2 (en) | 2005-06-01 | 2016-09-20 | Edison Pharmaceuticals, Inc. | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
| EP2471530A1 (en) | 2005-06-01 | 2012-07-04 | Edison Pharmaceuticals, Inc. | Redox-active Therapeutics For Treatment Of Mitochondrial Diseases And Other Conditions And Modulation Of Energy Biomarkers |
| US9278085B2 (en) | 2006-02-22 | 2016-03-08 | Edison Pharmaceuticals, Inc. | Side-chain variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
| US9932286B2 (en) | 2006-02-22 | 2018-04-03 | Bioelectron Technology Corporation | Side-chain variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
| US10105325B2 (en) | 2008-09-10 | 2018-10-23 | Bioelectron Technology Corporation | Treatment of pervasive developmental disorders with redox-active therapeutics |
| US10736857B2 (en) | 2008-09-10 | 2020-08-11 | Ptc Therapeutics, Inc. | Treatment of pervasive developmental disorders with redox-active therapeutics |
| US10981855B2 (en) | 2015-12-17 | 2021-04-20 | Ptc Therapeutics, Inc. | Fluoroalkyl, fluoroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders |
| US10703701B2 (en) | 2015-12-17 | 2020-07-07 | Ptc Therapeutics, Inc. | Fluoroalkyl, fluoroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders |
| US11680034B2 (en) | 2015-12-17 | 2023-06-20 | Ptc Therapeutics, Inc. | Fluoroalkyl, fluoroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders |
| CN117597335A (en) * | 2021-04-28 | 2024-02-23 | 帝斯曼知识产权资产管理有限公司 | Ring Closure of Benzoquinones Containing Unsaturated Side Chains Using Basic Catalysts |
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