JPH11503024A - 細胞表面のクラスｉ ｍｈｃタンパク質の低レベルを有する遺伝子学的に修飾された細胞の移植 - Google Patents
細胞表面のクラスｉ ｍｈｃタンパク質の低レベルを有する遺伝子学的に修飾された細胞の移植Info
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- JPH11503024A JPH11503024A JP8530474A JP53047496A JPH11503024A JP H11503024 A JPH11503024 A JP H11503024A JP 8530474 A JP8530474 A JP 8530474A JP 53047496 A JP53047496 A JP 53047496A JP H11503024 A JPH11503024 A JP H11503024A
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
- C12N2710/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
- C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Transplantation (AREA)
- Physics & Mathematics (AREA)
- Mycology (AREA)
- Developmental Biology & Embryology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41610695A | 1995-04-04 | 1995-04-04 | |
| US08/416,106 | 1995-04-04 | ||
| PCT/US1996/004648 WO1996031241A1 (fr) | 1995-04-04 | 1996-04-03 | Transplantation de cellules genetiquement modifiees presentant de faibles taux de proteines de classe i du complexe majeur d'histocompatibilite sur leur surface |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH11503024A true JPH11503024A (ja) | 1999-03-23 |
Family
ID=23648556
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8530474A Pending JPH11503024A (ja) | 1995-04-04 | 1996-04-03 | 細胞表面のクラスｉ ｍｈｃタンパク質の低レベルを有する遺伝子学的に修飾された細胞の移植 |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0820311A4 (fr) |
| JP (1) | JPH11503024A (fr) |
| KR (1) | KR19980703665A (fr) |
| AU (1) | AU712415B2 (fr) |
| CA (1) | CA2217297A1 (fr) |
| NO (1) | NO974596L (fr) |
| WO (1) | WO1996031241A1 (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998047914A2 (fr) * | 1997-04-18 | 1998-10-29 | Roche Diagnostics Gmbh | Gene us6 issu du cytomegalovirus humain |
| EP1045920A1 (fr) * | 1998-01-14 | 2000-10-25 | Human Gene Therapy Research Institute | Systemes d'expression nucleotidiques a immunogenicite reduite destines a la therapie genique |
| EP1020520A1 (fr) * | 1999-01-15 | 2000-07-19 | Introgene B.V. | Prévention d'élimination immunologiques des cellules du corps mammifère, molécules PML mutantes utiles à cet effet |
| CA2793959C (fr) * | 2010-03-25 | 2019-06-04 | Oregon Health & Science University | Glycoproteines du cmv et vecteurs recombines |
| CA2798136C (fr) | 2010-05-14 | 2019-06-04 | Oregon Health & Science University | Vecteurs recombinants du hcmv et du rhcmv, et leurs utilisations |
| US20120020885A1 (en) * | 2010-07-26 | 2012-01-26 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | MHC-Less cells |
| PT2691530T (pt) | 2011-06-10 | 2018-05-10 | Univ Oregon Health & Science | Glicoproteínas e vectores recombinantes cmv |
| JP6487026B2 (ja) | 2014-07-16 | 2019-03-20 | オレゴン ヘルス アンド サイエンス ユニバーシティ | 外来抗原を含むヒトサイトメガロウイルス |
| JP6816031B2 (ja) | 2015-02-10 | 2021-01-20 | オレゴン ヘルス アンド サイエンス ユニバーシティ | 非標準的なｃｄ８＋ｔ細胞応答を生成するのに有用な方法および組成物 |
| CA3005136A1 (fr) | 2015-11-20 | 2017-05-26 | Oregon Health & Science University | Vecteurs cmv comprenant des elements de reconnaissance des microarn |
| TN2019000124A1 (en) | 2016-10-18 | 2020-10-05 | Univ Oregon Health & Science | Cytomegalovirus vectors eliciting t cells restricted by major histocompatibility complex e molecules |
| KR20190141206A (ko) * | 2017-04-19 | 2019-12-23 | 알로젠 테라퓨틱스 인코포레이티드 | 개선된 t 세포 조성물 및 방법 |
| WO2019167973A1 (fr) * | 2018-03-01 | 2019-09-06 | Kyoto University | Inhibiteur d'évolution de cycle cellulaire |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0517895B1 (fr) * | 1990-12-14 | 1996-11-20 | Cell Genesys, Inc. | Chaines chimeriques utilisees comme voies de transduction de signal associe a un recepteur |
| AU5962694A (en) * | 1992-12-31 | 1994-08-15 | Exemplar Corporation | Producing cells for transplantation to reduce host rejection and resulting cells |
-
1996
- 1996-04-03 EP EP96912564A patent/EP0820311A4/fr not_active Withdrawn
- 1996-04-03 WO PCT/US1996/004648 patent/WO1996031241A1/fr not_active Application Discontinuation
- 1996-04-03 AU AU55338/96A patent/AU712415B2/en not_active Ceased
- 1996-04-03 JP JP8530474A patent/JPH11503024A/ja active Pending
- 1996-04-03 KR KR1019970707064A patent/KR19980703665A/ko not_active Application Discontinuation
- 1996-04-03 CA CA002217297A patent/CA2217297A1/fr not_active Abandoned
-
1997
- 1997-10-03 NO NO974596A patent/NO974596L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2217297A1 (fr) | 1996-10-10 |
| NO974596D0 (no) | 1997-10-03 |
| NO974596L (no) | 1997-12-03 |
| WO1996031241A1 (fr) | 1996-10-10 |
| EP0820311A4 (fr) | 2002-09-25 |
| AU5533896A (en) | 1996-10-23 |
| EP0820311A1 (fr) | 1998-01-28 |
| KR19980703665A (ko) | 1998-12-05 |
| AU712415B2 (en) | 1999-11-04 |
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