JPH0892056A - Whitening cosmetic - Google Patents

Abstract

PURPOSE: To obtain a cosmetic having extremely excellent whitening effect of skin and effect for preventing and treating stain and ephelis due to sun burn, etc. CONSTITUTION: This whitening cosmetic contains (A) an extract of Chamomillae Flos, (B) one or two or more plant extracts selected from among extracts of tea leaf, Pueraiae Radix, Caryophylli Flos, Glychyrrhizae Radix, Eriobotrya japonica Lindl., Aurantii Pericarpium, Ginseng Radix, Paenoiae Radix, Crataegi Fructus, Ophiopogonis Tuber, Zingiberis Rhizoma, Aurisclpium vulgare S.F. Gray, Mori Cortex, Magnoliae Cortex, Herba Artemisiae Capillaris, Gambir, Scutellariae Radix, Aloe, marshmallow root, Spiraea japonica L. fil., Rorippa nasturtium-aquaticum Hayek, Cinchonae Cortex, confrey, Rosmarinus and Scopoliae Folium and (C) one or two or more whitening agents selected from among L-ascorbic acid, its derivative, hydroquinone derivative, kojic acid and its derivative and placenta extract.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a whitening cosmetic composition having an excellent skin whitening effect and capable of preventing and treating spots and freckles caused by sunburn.

[0002]

BACKGROUND OF THE INVENTION Skin spots and freckles are generally caused by pigment cells (melanocytes) caused by irritation or hormonal abnormality caused by exposure to ultraviolet rays from sunlight, or genetic factors. As a result of being activated,
It is believed that the melanin pigment synthesized in pigment cells is abnormally deposited in the skin.

Conventionally, L-ascorbic acid and its derivatives, hydroquinone derivatives, kojic acid and its derivatives, melanin inhibitors such as placenta extracts, etc. have been used as a method for preventing or treating such spots and freckles. However, when these substances were used alone, the melanin production inhibitory effect was weak, and when blended in cosmetics and the like, many of them could not exhibit a sufficient whitening effect.

Therefore, there has been a demand for a whitening cosmetic which has an excellent whitening effect on the skin and can effectively prevent and treat spots and freckles.

[0005]

[Means for Solving the Problems] In view of such a situation,
As a result of intensive studies by the present inventors, the combined use of chamomile extract, a specific plant extract and a specific whitening agent synergistically enhances the whitening effect, effectively preventing and treating spots and freckles. It was found that a whitening cosmetic that can be obtained is obtained, and the present invention has been completed.

That is, the present invention provides the following component (A),
(B) and (C): (A) chamomile extract, (B) tea, kakkon, koji, licorice,
Loquat, orange peel, ginseng, peony, yamashiko, bakumon winter, ginger,
One or more plants selected from extracts of matsukasa, mulberry bark, magnolia, linden, assenyaku, yellow gon, aloe, altea, spirea, duck, kina, comfrey, rosemary, and funnel. It is intended to provide a whitening cosmetic composition containing one or more whitening agents selected from an extract, (C) L-ascorbic acid and its derivative, a hydroquinone derivative, kojic acid and its derivative, and a placenta extract.

The chamomile extract of the component (A) used in the present invention is a chamomile [Matricaria cham
omilla L. (Compositae)] flower can be obtained as an extract by extracting with water or a hydrophilic organic solvent such as methanol, ethanol, propanol, propylene glycol, 1,3-butylene glycol, or a mixed solvent thereof. The extract can be dried and obtained in the form of a dry powder. Further, it is extracted with a lipophilic organic solvent such as castor oil, persic oil, liquid paraffin, soybean oil, isopropyl myristate, lower fatty acid triglyceride, intermediate fatty acid triglyceride, sunflower oil, neopentyl glycol dicaprate, squalane, or a mixed solvent thereof. Can be obtained. In the present invention, one kind or two or more kinds of chamomile extracts thus obtained can be used in combination.

The chamomile extract generally contains azulene, chamazulen, umbelliferone, 7-methoxycoumarin, matricin, matricalin, taraxasterol, lupeol, apiin, chroman and the like. Here, as a preferable extraction method of chamomile, the following method can be mentioned, for example.

The chamomile flowers are dried and chopped. Squalane is added thereto, and the mixture is immersed at room temperature to 50 ° C. with occasional stirring, and then squeezed to obtain an extract. The extract is filtered to give a chamomile extract.

The blending amount of component (A) is not particularly limited, but from the viewpoint of whitening effect and storage stability, it is preferable to blend in 0.00001 to 5% by weight as a solid content in the total amount of the cosmetic. It is preferable to add 0.0005 to 3% by weight, more preferably 0.001 to 2% by weight, because a sufficient whitening effect can be obtained and the storage stability of the product is excellent.

Ingredient (B) used in the present invention is tea, kakkon, choji, licorice, loquat, orange peel, ginseng, peony, yamseiko, bakumondofu, ginger, matsukasa, mulberry bark, koboku, sardine. It is one or more kinds of plant extracts selected from extracts of Chen linseed, Asenyaku, yellow gon, aloe, altea, spirea, Dutch pepper, chrysanthemum, comfrey, rosemary and funnel, among which tea is particularly preferred. It is preferable to use peony, ginger, Altea, Dutch pepper, rosemary and funnel.

These plant extracts can be obtained by the same operations as those for the chamomile extract.

The blending amount of the component (B) is not particularly limited, but from the viewpoints of whitening effect and storage stability, it is preferable to blend 0.00001 to 5% by weight in solid content in the total amount of the cosmetic. , Especially 0.0005 to 3% by weight, and further 0.0
When it is blended in an amount of 0.01 to 3% by weight, a sufficient whitening effect is obtained and the storage stability is good, which is preferable.

Of the whitening agents of component (C) used in the present invention, ascorbic acid and its derivatives are not particularly limited and include, for example, L-ascorbic acid phosphate, which is a monovalent metal salt of L-. Ascorbic acid phosphoric acid sodium salt, L-ascorbic acid phosphoric acid potassium salt, divalent metal salt L-ascorbic acid phosphoric acid magnesium salt, L-ascorbic acid phosphoric acid calcium salt, trivalent metal salt L-ascorbic acid phosphoric acid ester aluminum salt, L-ascorbic acid sulfuric acid ester sodium salt which is a monovalent metal salt of L-ascorbic acid sulfuric acid ester, L-ascorbic acid sulfuric acid ester potassium salt, L-ascorbic acid sulfuric acid ester divalent metal salt Ascorbic acid sulfate potassium magnesium salt, L
-Ascorbic acid sulfate calcium salt, trivalent metal salt L-ascorbic acid sulfate aluminum salt, L-ascorbic acid monovalent metal salt L-ascorbic acid sodium salt, L-ascorbic acid potassium salt, divalent Preferred examples include metal salts such as magnesium L-ascorbate, calcium L-ascorbate and trivalent metal salts such as aluminum L-ascorbate.

The hydroquinone derivative is not particularly limited, and examples thereof include a condensate of hydroquinone and a sugar, a condensate of an alkylhydroquinone and a sugar in which one alkyl group having 1 to 4 carbon atoms is introduced into hydroquinone, and the like. Of these, preferred examples include arbutin and the like.

The kojic acid and its derivative are not particularly limited and include, for example, kojic acid, kojic acid monobutyrate, kojic acid monocaprate, kojic acid monopalmitate, kojic acid monostearate, kojic acid monocinnamoate, Preferable examples include monoesters such as kojic acid monobenzoate, diesters such as kojic acid dibutyrate, kojic acid dipalmitate, kojic acid distearate, and kojic acid dioleate.

As the placenta extract, those generally marketed as water-soluble placenta extracts and used as a raw material for cosmetics can be used. For example, the placenta of a mammal such as cow, pig or human can be washed, bleeding, crushing, Examples thereof include those obtained by extracting water-soluble components through steps such as freezing and then removing impurities.

Of these, ascorbic acid and its derivatives or placenta extracts are preferably used as the component (C).

The component (C) whitening agent may be used alone or in combination of two or more, and the compounding amount thereof is not particularly limited, but the whitening effect, the storage stability and the feeling of use. From the point of, 0.01 to 30 in the total amount of cosmetics
It is preferably blended in an amount of 0.01% by weight, particularly preferably 0.01 to 10% by weight, more preferably 0.01 to 5% by weight, since a sufficient whitening effect can be obtained and stability is good.

The whitening cosmetic composition of the present invention preferably further contains one or more selected from organic acids or organic acid salts. The organic acid refers to a compound containing one or more carboxyl groups in one molecule, for example, lactic acid, citric acid, tartaric acid, glyceric acid, malic acid, succinic acid, glycolic acid, fumaric acid, amino acid, carboxylic acid, oxy Examples thereof include carboxylic acid. The organic acid salt is a metal salt of these organic acids, and examples of the metal salt include sodium salt, potassium salt, calcium salt, magnesium salt and the like.

Further, the whitening cosmetic composition of the present invention may optionally contain various optional components used in cosmetics, quasi-drugs, pharmaceuticals and the like, in addition to the above components, as long as the effects of the present invention are not impaired. It can be blended. Examples of such optional components include purified water, ethanol, oily substances, moisturizers, thickeners, preservatives, emulsifiers, medicinal components, powders, ultraviolet absorbers, pigments, fragrances, emulsion stabilizers, etc. You can

Examples of the oily component include liquid paraffin, petrolatum, paraffin wax, squalane, beeswax, carnauba wax, olive oil, lanolin, higher alcohols, fatty acids, synthetic ester oils of higher alcohols and fatty acids, silicone oils and the like. As a moisturizer,
Examples thereof include sorbitol, xylitol, glycerin, maltitol, propylene glycol, 1,3-butylene glycol, 1,4-butylene glycol, sodium pyrrolidonecarboxylate, lactic acid, sodium lactate, polyoxypropylene fatty acid ester and polyethylene glycol. Examples of the thickener include water-soluble polymers such as carboxyvinyl polymer, carboxymethyl cellulose, polyvinyl alcohol, carrageenan and gelatin, and electrolytes such as sodium chloride and potassium chloride. Examples of preservatives include urea, methylparaben,
Ethylparaben, propylparaben, butylparaben,
Examples thereof include sodium benzoate. As an emulsifier,
For example, polyoxyethylene alkyl ether, polyoxyethylene fatty acid ester, polyoxyethylene sorbitan fatty acid ester, glycerin fatty acid ester, polyglycerin fatty acid ester, polyoxyethylene glycerin fatty acid ester, polyoxyethylene hydrogenated castor oil, polyoxyethylene sorbitol fatty acid ester, etc. Nonionic surfactants of As powder,
For example, talc, sericite, mica, kaolin, silica, bentonite, vermiculite, zinc white, mica,
Examples thereof include titanium mica, titanium oxide, magnesium oxide, zirconium oxide, barium sulfate, red iron oxide, iron oxide and ultramarine.

The whitening cosmetic composition of the present invention can be manufactured by a conventional method. In addition, the whitening cosmetic subject to the present invention is not limited to general skin cosmetics, but includes quasi drugs, external medicines, etc., and its dosage form also depends on its purpose. It can be arbitrarily selected and can be in the form of cream, ointment, emulsion, lotion, solution, gel, pack, powder, stick or the like.

[0024]

EFFECTS OF THE INVENTION The whitening cosmetic composition of the present invention is very excellent because a synergistic melanin production inhibiting effect is obtained by using a chamomile extract, a specific plant extract and a specific whitening agent in combination. It has a whitening effect on the skin and is effective in preventing and treating spots and freckles due to sunburn and the like.

[0025]

EXAMPLES Next, the present invention will be described with reference to examples.
The invention is in no way limited to these examples. The whitening effect in the examples was evaluated by the whitening effect test for UV-B-induced pigment spots shown below.

(Whitening Effect Test on UV-B Induced Pigment Spots) 20 subjects were irradiated with UV rays in the UV-B region at twice the minimum erythema dose once a day for 2 days to induce them. The whitening effect of the continuous application of the sample to the test site on the pigment spots twice a day for one month was examined.

A color difference meter (Murakami Color, CMS-1 was used for evaluation.
200) and L ^* value was calculated from the obtained Munsell value, and the ΔΔL ^* value representing the recovery was used. The ΔΔL ^* value was defined as follows.

Immediately before the start of application of the sample, the L ^* values of the sample-applied test site and the sample-unapplied test site were L ₀ and L ₀ ^′ , respectively, and the L ^* values of the sites 1 month after continuous application were L ₁ and L, respectively. ₁ ^'
And ΔΔL ^* is expressed by the following equation.

[0029]

[Formula 1] ΔΔL ^* = (L ₁ −L ₀ ) − (L ₁ ^′ −L ₀ ^′ )

The evaluation is shown by the average value of the evaluation points shown in Table 1 of 20 subjects.

[0031]

[Table 1]

Examples 1 to 10 and Comparative Examples 1 to 7 A cream containing chamomile extract, various plant extracts other than chamomile and a whitening agent in a composition shown in Table 2 was prepared according to the composition shown in Table 3 and continuously applied. The whitening effect by the above was evaluated by the method described above. The results are shown in Table 3.

[0033]

[Table 2]

[0034]

[Table 3]

(Production Method) The oil layer component was heated and dissolved at 80 ° C., the aqueous layer heated to 60 ° C. was added with stirring to emulsify, and the mixture was cooled to room temperature with stirring to prepare a cream.

[0036]

[Table 4]

From the results shown in Table 4, it was confirmed that the whitening cream of the present invention synergistically improves the whitening effect and obtains an excellent whitening effect.

Example 11 Emulsion

[0039]

[Table 5]

(Production Method) The oil layer component was heated and dissolved at 80 ° C. and stirred to add an aqueous layer heated at 60 ° C. to emulsify. After the emulsification was completed, the mixture was cooled to room temperature with stirring to prepare an emulsion.

Example 12 Essence

[0042]

[Table 6]

(Manufacturing Method) The oil layer component was heated and dissolved at 80 ° C. and stirred to add an aqueous layer heated to 80 ° C. to emulsify. After completion of the emulsification, the mixture was cooled to room temperature with stirring to prepare an essence.

Example 13 Lotion

[0045]

[Table 7]

(Manufacturing method) The lotion was prepared by heating and dissolving the blended components at 80 ° C. until the system became uniform, and further stirring and cooling to room temperature.

Example 14 Powder

[0048]

[Table 8]

(Production method) The ingredients were uniformly stirred and mixed to prepare a powder.

Example 15 Pack

[0051]

[Table 9]

(Manufacturing Method) The ingredients were uniformly stirred and mixed, and then cooled to room temperature to prepare a pack.

Claims (2)

[Claims] 1. The following components (A), (B) and (C): (A) chamomile extract, (B) tea, kakkon, clove, licorice,
Loquat, orange peel, ginseng, peony, yamashiko, bakumon winter, ginger,
One or more plants selected from extracts of matsukasa, mulberry bark, magnolia, linden, assenyaku, yellow gon, aloe, altea, spirea, duck, kina, comfrey, rosemary, and funnel. A whitening cosmetic containing one or more whitening agents selected from the extract, (C) L-ascorbic acid and its derivative, hydroquinone derivative, kojic acid and its derivative, and placenta extract. 2. The components (A) and (B) are each added to 0.0
The whitening cosmetic composition according to claim 1, which comprises 0001 to 5% by weight and 0.01 to 30% by weight of the component (C).