JPH08268834A - W/o-type emulsion composition - Google Patents

Abstract

PURPOSE: To obtain the subject composition excellent in emulsion stability, safety and usability, containing ethylhydroxyethyl cellulose and a polyion complex composed of two kinds of polyelectrolytes with electric charges opposite to each other. CONSTITUTION: This W/O-type emulsion composition is obtained by formulating an oily phase with 0.1-20wt.% of ethylhydroxyethyl cellulose as liposoluble polymer and by formulating an aqueous phase with 0.01-5wt.% of a polyion complex which is derived from a cationized cellulose and hyaluronic acid at the weight ratio of (9:1) to (8:2). Besides, the composition is also incorporated, as necessary, with a humectant, medicinal agent, ultraviolet light absorber, antiseptic agent, antioxidant, etc. Specifically, the composition is prepared by first emulsifying a part of the oily phase to O/W type followed by gradually adding the resultant emulsion to the rest of the oily phase.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an emulsified composition, and more particularly to an emulsified composition containing ethylhydroxyethyl cellulose and a polyion complex (polymer electrolyte complex) composed of a polyelectrolyte having opposite charges. It relates to a composition.

[0002]

2. Description of the Related Art In recent years, many studies on emulsification have been carried out, many emulsifiers have been developed, and the emulsification technology has made remarkable progress, and very stable emulsions have been widely used in all industries. However, most of them use nonionic surfactants containing polyoxyethylene chains, anionic surfactants represented by fatty acid soaps, and amphoteric surfactants as emulsifiers, which are especially safe among general consumers. Many have anxiety about sex.

Therefore, the use of a water-soluble polymer, which is considered to be highly safe in recent years, as an emulsifier has been studied. However, compared with the so-called "surfactants" such as the above-mentioned nonionic surfactants, the water-soluble polymer has a small interfacial tension lowering ability, so that the emulsifying power is relatively small and the emulsion stability is poor. In addition, since the emulsion system is easily destroyed during application, it is not so familiar with the skin and so-called "repellency" is recognized.

[0004]

In view of the above circumstances, the present invention has an object of providing an emulsion composition having good emulsion stability, safety and usability.

[0005]

Means for Solving the Problems As a result of earnest research, the present inventor has found that the above object can be achieved by using a combination of ethylhydroxyethyl cellulose and a polyion complex composed of a polyelectrolyte having opposite charges. The invention was completed.

That is, in the present invention, ethyl hydroxyethyl cellulose is blended in the oil phase as an oil-soluble polymer,
Further, W / which has good emulsion stability, safety and usability, which is characterized in that a polyion complex comprising a polyelectrolyte having opposite charges is blended in the aqueous phase.
It is an O-type emulsion composition.

[0007]

Next, the structure of the present invention will be described in detail.

Ethyl hydroxyethyl cellulose (hereinafter referred to as EHEC) which is an oil-soluble polymer used in the present invention.
Is abbreviated), in which most of the three hydroxyl groups of cellulose are substituted with ethoxyl or ethyl hydroxyl groups. EHEC is usually used by dissolving or swelling it in an oil component used in the fields of cosmetics, pharmaceuticals, foods and the like. For example, methylphenyl polysiloxane is preferred as the solubilizer. The amount of EHEC blended is 0.1 to 20 relative to the oil phase forming the continuous phase of the W / O type emulsion composition.
Weight% is preferable, and 1 to 10 weight% is more preferable.

The oil used in the present invention is as follows:
For example, beef tallow, squalane, animal and vegetable oils such as olive oil, beeswax, lanolin, waxes such as candelilla wax and hydrocarbons, liquid paraffin, mineral oils such as vaseline, ester oils, silicone oils, higher alcohols,
Fatty acid etc. are mentioned.

Next, the polyion complex (hereinafter abbreviated as PIC) used in the present invention includes, for example, cationized cellulose (hereinafter abbreviated as PJR) and hyaluronic acid (hereinafter abbreviated as HA) or a salt thereof. To be Here, the composition ratio of PJR and HA is PJ by weight ratio.
R: HA = 9: 1 to 8: 2 is preferable. The content of PIC is preferably 0.01 to 5% by weight, more preferably 0.05 to 5% by weight, based on the aqueous phase forming the discontinuous phase of the W / O type emulsion composition.
2% by weight is more preferred.

In addition to the above-mentioned essential components, a moisturizing agent, a drug, an ultraviolet absorber, a preservative, and an antioxidant may be added to the emulsion composition of the present invention. Also,
The ratio of oil phase to water phase can be selected within a wide range. The method for obtaining the emulsified composition of the present invention depends on the method for preparing a usual W / O type emulsified composition, but a part of the oil phase is first emulsified into the O / W type, and this is gradually added to the remaining oil phase. It is also possible to add it to.

[0012]

EXAMPLES The present invention will be described in more detail with reference to experimental examples, examples and comparative examples. The present invention is not limited to this.

Test Examples 1 to 5 0.1% PJR aqueous solution and 0.1% HA aqueous solution were mixed at various weight ratios, and the state of the mixed solution was observed. The results are shown in Table 1.

[0014]

[Table 1] As can be seen from Table 1, the state of the mixed solution was classified into three types, that is, dissolution, cloudiness and precipitation, depending on the cation / anion composition ratio.
Next, emulsification was performed using a PIC aqueous solution having each composition ratio.

(Comparative Examples 1 to 4 and Examples 1 to 3) The emulsified compositions were prepared by blending in the blending compositions and amounts shown in Table 2 and subjecting to 70 ° C. disper treatment. The state of the emulsified composition was observed, filled in a glass bottle, allowed to stand at 50 ° C. for 1 month, and then evaluated for stability. The stability was evaluated according to the following three grades.

◯: No separation was observed at all Δ: Slight separation of oil phase or water phase was observed ×: Oil phase or water phase was significantly separated
The results are shown in Table 2. The numbers of each component are% by weight.

[0017]

[Table 2] As shown in Table 2, when emulsified using EHEC and PJR, an emulsion with good stability could not be obtained unless a large amount of PJR was blended (Comparative Examples 1 and 5). Large-scale use is not preferable in terms of safety. Also,
When emulsified using EHEC and HA (Comparative Example 4,
No stable W / O type emulsion composition was obtained in 6).
Further, when emulsified with a composition in which PIC becomes a precipitate (Comparative Examples 2 and 3), a stable W / O type emulsified composition could not be obtained. On the other hand, in Examples 1 to 3 according to the present invention, O / W type emulsion compositions having good stability were obtained. (Example 4) Moisture cream wt% (A) EHEC 0.5 Vaseline 0.5 Methylphenylpolysiloxane 5.0 Glyceryl diisostearate 2.0 Jojoba oil 2.0 Cetyl alcohol 0.5 Isostearyl alcohol 0.5 Vitamin E Acetate 0.5 Preservative 0.1 Perfume 0.1 (B) Glycerin 10.0 1,3 Butylene glycol 5.0 Cationized cellulose 0.45 Hyaluronic acid-Na 0.05 Purified water Residual (A) phase It melted uniformly at 70 ° C. PIC was uniformly dispersed in this, and phase (B) heated to 70 ° C. was gradually added under stirring with a disper, after completion of the addition, a disper treatment was performed at 6000 rpm for 2 minutes, followed by stirring and cooling to obtain Example 4. . The obtained moisture cream had excellent stability over time, had very good spreadability when applied to the skin, and had use characteristics in which "repellency" was not observed. In addition, it was confirmed that there were no safety problems.

Example 5 Night Cream Weight% (A) EHEC 1.0 Liquid paraffin 2.0 Vaseline 1.0 Methylphenylpolysiloxane 7.0 Glyceryl trioctanoate 5.0 Olive oil 5.0 Isostearate 1.0 Vitamin E Acetate 0.5 Preservative 0.1 Perfume 0.1 (B) Glycerin 5.0 1,3 Butylene glycol 5.0 Cationized cellulose 0.4 Hyaluronic acid 0.1 Purified water Residual Preparation method is Example 4 Same as. The obtained moisture cream has excellent stability over time, and when applied to the skin,
It had a very good spreadability and had usage characteristics in which "repellency" was not recognized. In addition, it was confirmed that there were no safety problems. (Example 6) Sun care cream wt% (A) EHEC 3.0 Liquid paraffin 3.0 Vaseline 1.0 Methylphenyl polysiloxane 10.0 Jojoba oil 5.0 Octyl methoxycinnamate 10.0 Vitamin E acetate 0 .5 Preservative 0.1 Perfume 0.1 (B) Glycerin 5.0 Cationized cellulose 0.8 Hyaluronic acid 0.2 Purified water Residual PIC was uniformly dispersed in phase (B) under homomixer agitation with octylmethoxy. O / W emulsion was prepared by adding cinnamate. Next, the emulsion is heated to 70 ° C.,
Example 6 was obtained by gradually adding to the residue of the (A) phase that was uniformly dissolved at 70 ° C. under stirring with a disper. The obtained sun care cream had excellent stability over time, had very good spreadability when applied to the skin, and had use characteristics in which "repellency" was not observed. In addition, the formulation was also excellent in water resistance and was able to sufficiently exert the effect of the ultraviolet absorber.

[0019]

According to the present invention, it is possible to provide an emulsion composition having good stability, safety and usability without using a surfactant.

Claims (3)

[Claims] 1. A W / O type emulsion composition comprising an oil phase containing ethylhydroxyethyl cellulose and an aqueous phase containing a polyion complex which is dissolved or colloidally dispersed in water. 2. A W / O type emulsion composition, wherein the composition ratio of polycation and polyanion is 9: 1 to 8: 2. 3. The W / O type emulsion composition according to claim 1, wherein the polyion complex is composed of cationized cellulose and hyaluronic acid or a salt thereof.