JPH0768272B1 - - Google Patents

Info

Publication number: JPH0768272B1
Authority: JP; Japan
Prior art keywords: cells; fibroblasts; glycoprotein; accelerating; proliferation
Prior art date: 1989-03-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

JP2504271A

Other languages

English (en)

Inventor

Kanji Higashio

Shinjiro Mitsuda

Nobuyuki Shima

Yasuharu Itagaki

Masaya Nagao

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Snow Brand Milk Products Co Ltd

Original Assignee

Snow Brand Milk Products Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-03-10

Filing date

1990-03-09

Publication date

1995-07-26

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26340889&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPH0768272(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1990-03-09 Application filed by Snow Brand Milk Products Co Ltd filed Critical Snow Brand Milk Products Co Ltd

1995-07-26 Publication of JPH0768272B1 publication Critical patent/JPH0768272B1/ja

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicinal Preparation (AREA)

JP2504271A 1989-03-10 1990-03-09 Expired - Lifetime JPH0768272B1 (ja)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP5863189		1989-03-10
JP669290		1990-01-16
PCT/JP1990/000314 WO1990010651A1 (fr)	1989-03-10	1990-03-09	Glycoproteine humaine, facteur physiologiquement actif la contenant, et preparation pharmaceutique le contenant en tant qu'ingredient actif

Related Child Applications (2)

Application Number	Title	Priority Date	Filing Date
JP6218183A Division JP2747979B2 (ja)	1994-08-19	1994-08-19	ヒト由来の糖蛋白質からなる生理活性因子を有効成分とする医薬
JP8191458A Division JPH0925297A (ja)	1996-07-01	1996-07-01	ヒト由来の糖蛋白質及び該糖蛋白質からなる生理活性因子とそれを活性成分とする製剤

Publications (1)

Publication Number	Publication Date
JPH0768272B1 true JPH0768272B1 (ja)	1995-07-26

Family

ID=26340889

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP2504271A Expired - Lifetime JPH0768272B1 (ja)	1989-03-10	1990-03-09

Country Status (17)

Country	Link
US (2)	US5587359A (ja)
EP (1)	EP0462277B1 (ja)
JP (1)	JPH0768272B1 (ja)
KR (1)	KR960009054B1 (ja)
AT (1)	ATE123498T1 (ja)
AU (1)	AU629314B2 (ja)
CA (1)	CA2049017C (ja)
DE (1)	DE69019962T2 (ja)
DK (1)	DK0462277T3 (ja)
ES (1)	ES2075199T3 (ja)
FI (1)	FI102681B1 (ja)
HU (2)	HU212513B (ja)
IE (1)	IE64005B1 (ja)
NO (1)	NO180796C (ja)
NZ (1)	NZ232813A (ja)
RU (1)	RU2113480C1 (ja)
WO (1)	WO1990010651A1 (ja)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5362716A (en) *	1989-12-27	1994-11-08	The United States Of America As Represented By The Department Of Health And Human Services	Methods for stimulating hematopoietic progenitors using hepatocyte growth factor and lymphokines
DE69133492T2 (de) *	1990-06-11	2006-08-10	Nakamura, Toshikazu	Rekombinanter menschlicher Hepatozytwachstumsfaktor und Verfahren zu seiner Herstellung
CA2066618C (en) *	1990-07-13	1998-05-19	Nobuyuki Shima	Plasmids containing dna encoding the amino acid sequence of tcf-ii, transformed cells with the plasmids, and production method of biologically active substance using the transformed cells
AU650292B2 (en) *	1990-09-14	1994-06-16	United States of America, as represented by the Secretary, U.S. Department of Commerce, The	A non-mitogenic competitive HGF antagonist
US5821223A (en) *	1990-09-14	1998-10-13	The United States Of America As Represented By The Department Of Health And Human Services	Method of stimulating cell growth with a novel broad spectrum human lung fibroblast-derived mitogen
JP3200609B2 (ja) *	1990-12-28	2001-08-20	敏一中村	上皮細胞増殖促進剤
JPH0597A (ja) *	1991-06-21	1993-01-08	Snow Brand Milk Prod Co Ltd	新規抗ｔｃｆ−ｉｉモノクローナル抗体及びそれを用いるｔｃｆ−ｉｉの測定方法
JP3380573B2 (ja)	1992-07-16	2003-02-24	第一製薬株式会社	Ｔｃｆ−ｉｉを有効成分とする蛋白合成促進剤
DK0588477T3 (da)	1992-07-16	1998-03-30	Snow Brand Milk Products Co Ltd	Medicinsk præparat omfatende TCF-11
KR100260964B1 (ko) *	1992-07-16	2000-07-01	쇼노 카츄야	Tcf-ii를 유효성분으로 하는 혈액응고 정상화제
WO1994014845A1 (en) *	1992-12-28	1994-07-07	Snow Brand Milk Products Co., Ltd.	Modified tcf
JP3552240B2 (ja) *	1993-02-23	2004-08-11	第一製薬株式会社	高濃度ｔｃｆ製剤
US5837676A (en) *	1993-10-18	1998-11-17	Long Island Jewish Medical Center	Use of scatter factor to enhance angiogenesis
JP2747979B2 (ja) *	1994-08-19	1998-05-06	雪印乳業株式会社	ヒト由来の糖蛋白質からなる生理活性因子を有効成分とする医薬
JPH08176007A (ja) *	1994-12-27	1996-07-09	Snow Brand Milk Prod Co Ltd	脂質代謝異常治療剤
ATE248913T1 (de) *	1994-12-27	2003-09-15	Daiichi Seiyaku Co	Tcf mutante
AU4027601A (en) *	1995-07-11	2001-07-26	Snow Brand Milk Products Co., Ltd.	Lyophilized HGF preparations
JP3927248B2 (ja) *	1995-07-11	2007-06-06	第一製薬株式会社	Ｈｇｆ凍結乾燥製剤
JP4006058B2 (ja)	1997-03-11	2007-11-14	第一三共株式会社	多臓器不全予防及び／又は治療剤
EP0950416B1 (en)	1997-03-14	2006-11-02	Daiichi Pharmaceutical Co., Ltd.	Use of TCF-II for the treatment of cancer related body weight loss, anaemia and TNF elevation
JPH1129493A (ja) *	1997-07-14	1999-02-02	Snow Brand Milk Prod Co Ltd	放射線障害予防及び／又は治療剤
JPH11269091A (ja) *	1998-03-19	1999-10-05	Snow Brand Milk Prod Co Ltd	敗血症予防及び／又は治療剤
CN1352087A (zh) *	2000-11-02	2002-06-05	上海博德基因开发有限公司	一种新的多肽——人糖蛋白42和编码这种多肽的多核苷酸
KR100562824B1 (ko) *	2002-03-20	2006-03-23	주식회사 바이로메드	유전자 발현효율이 높으며 간세포 성장인자의 두 가지이형체를 동시에 발현하는 하이브리드 간세포 성장인자유전자
US7563810B2 (en)	2002-11-06	2009-07-21	Celgene Corporation	Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases
US8034831B2 (en)	2002-11-06	2011-10-11	Celgene Corporation	Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies
CN100417412C (zh) *	2003-03-28	2008-09-10	威海赛洛金药业有限公司	促肝细胞生长素注射液及制备方法和应用
JP4728807B2 (ja) *	2003-09-03	2011-07-20	敏一中村	ヒト組換えｈｇｆを含有する皮膚潰瘍予防治癒剤
BRPI0707268A2 (pt) *	2006-01-25	2011-04-26	Octapharma Ag	purificação e uso de um fator para ajudar a cura de ferimento
US20100124782A1 (en) *	2007-04-28	2010-05-20	Applied Cell Biotechnologies, Inc.	Composition For Repairing Defect In Skin Or Gingival Soft Tissue And Method Of Culturing Autologous Fibroblasts
US20090202606A1 (en) *	2008-01-25	2009-08-13	Viromed Co., Ltd.	Treatment and Prevention of Cardiac Conditions Using Two or More Isoforms of Hepatocyte Growth Factor
US20090258932A1 (en) *	2008-04-09	2009-10-15	Viromed Co., Ltd.	Lyophilized DNA Formulations for Enhanced Expression of Plasmid DNA
RU2639582C2 (ru)	2013-10-22	2017-12-21	Виромед Ко., Лтд.	Композиция для предупреждения или лечения бокового амиотрофического склероза с использованием двух или более изоформ фактора роста гепатоцитов
RU2693472C2 (ru)	2014-04-28	2019-07-03	Эйсай Ар Энд Ди Менеджмент Ко., Лтд.	Лиофилизированный состав на основе hgf
CA2958342C (en)	2014-09-10	2019-09-24	Kringle Pharma Inc.	Hgf preparation suitable for treatment of neurological disorders
MX395311B (es)	2016-03-17	2025-03-25	Eisai R&D Man Co Ltd	Metodo para producir factor de crecimiento de hepatocitos (hgf) activo.
CN112088017B (zh)	2018-07-19	2023-11-21	赫利世弥斯株式会社	用于裸脱氧核糖核酸基因疗法的经冷冻干燥的药剂学组合物
US20230022990A1 (en)	2021-05-14	2023-01-26	Claris Biotherapeutics, Inc.	Compositions of growth factor for the treatment of eye disease

Citations (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS63165328A (ja) *	1986-12-18	1988-07-08	ベーリングヴエルケ・アクチエンゲゼルシヤフト	組織タンパクｐｐ４含有医薬
JPS63243032A (ja) *	1987-03-27	1988-10-07	Green Cross Corp:The	トロンビンの加熱処理方法
JPS6458631A (en) *	1987-08-26	1989-03-06	Toppan Printing Co Ltd	Container material molding equipment
JPS6471818A (en) *	1987-09-05	1989-03-16	Boehringer Mannheim Gmbh	Storage-stable and tolerable human protein medicine and manufacture
JPH026692A (ja) *	1987-10-29	1990-01-10	Laennen Tehtaat Oy	改質紙

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS58148826A (ja) *	1982-02-26	1983-09-05	Mochida Pharmaceut Co Ltd	糖蛋白質および腫瘍治療剤
JP2564486B2 (ja) *	1986-07-14	1996-12-18	修治橋本	肝細胞増殖因子
US5037644A (en) *	1986-10-27	1991-08-06	Cetus Corporation	Pharmaceutical compositions of recombinant interleukin-2 and formulation processes
JPS6410998A (en) *	1986-12-22	1989-01-13	Green Cross Corp	Tumor cell inhibitory factor
CA2066618C (en) *	1990-07-13	1998-05-19	Nobuyuki Shima	Plasmids containing dna encoding the amino acid sequence of tcf-ii, transformed cells with the plasmids, and production method of biologically active substance using the transformed cells

1990
- 1990-03-06 NZ NZ232813A patent/NZ232813A/en unknown
- 1990-03-09 DE DE69019962T patent/DE69019962T2/de not_active Expired - Lifetime
- 1990-03-09 RU RU95110767A patent/RU2113480C1/ru active
- 1990-03-09 JP JP2504271A patent/JPH0768272B1/ja not_active Expired - Lifetime
- 1990-03-09 CA CA002049017A patent/CA2049017C/en not_active Expired - Lifetime
- 1990-03-09 KR KR1019910701058A patent/KR960009054B1/ko not_active Expired - Fee Related
- 1990-03-09 WO PCT/JP1990/000314 patent/WO1990010651A1/ja active IP Right Grant
- 1990-03-09 EP EP90904429A patent/EP0462277B1/en not_active Expired - Lifetime
- 1990-03-09 HU HU902330A patent/HU212513B/hu unknown
- 1990-03-09 AT AT90904429T patent/ATE123498T1/de not_active IP Right Cessation
- 1990-03-09 DK DK90904429.9T patent/DK0462277T3/da active
- 1990-03-09 AU AU51774/90A patent/AU629314B2/en not_active Expired
- 1990-03-09 ES ES90904429T patent/ES2075199T3/es not_active Expired - Lifetime
- 1990-03-09 IE IE86390A patent/IE64005B1/en not_active IP Right Cessation
1991
- 1991-09-09 NO NO913546A patent/NO180796C/no not_active IP Right Cessation
- 1991-09-09 FI FI914234A patent/FI102681B1/fi active
1994
- 1994-09-12 US US08/304,419 patent/US5587359A/en not_active Expired - Lifetime
1995
- 1995-06-02 HU HU95P/P00149P patent/HU211229A9/hu unknown
1996
- 1996-03-19 US US08/617,621 patent/US6333309B1/en not_active Expired - Fee Related

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS63165328A (ja) *	1986-12-18	1988-07-08	ベーリングヴエルケ・アクチエンゲゼルシヤフト	組織タンパクｐｐ４含有医薬
JPS63243032A (ja) *	1987-03-27	1988-10-07	Green Cross Corp:The	トロンビンの加熱処理方法
JPS6458631A (en) *	1987-08-26	1989-03-06	Toppan Printing Co Ltd	Container material molding equipment
JPS6471818A (en) *	1987-09-05	1989-03-16	Boehringer Mannheim Gmbh	Storage-stable and tolerable human protein medicine and manufacture
JPH026692A (ja) *	1987-10-29	1990-01-10	Laennen Tehtaat Oy	改質紙

Also Published As

Publication number	Publication date
CA2049017A1 (en)	1990-09-11
FI102681B (fi)	1999-01-29
FI914234A0 (fi)	1991-09-09
KR920701256A (ko)	1992-08-11
DK0462277T3 (da)	1995-10-30
NO913546L (no)	1991-11-11
ES2075199T3 (es)	1995-10-01
CA2049017C (en)	1998-10-27
HU902330D0 (en)	1991-12-30
KR960009054B1 (ko)	1996-07-10
US5587359A (en)	1996-12-24
HUT58797A (en)	1992-03-30
US6333309B1 (en)	2001-12-25
NO180796C (no)	1997-06-25
IE900863L (en)	1990-09-10
AU5177490A (en)	1990-10-09
FI102681B1 (fi)	1999-01-29
RU2113480C1 (ru)	1998-06-20
EP0462277A4 (en)	1992-08-12
DE69019962D1 (de)	1995-07-13
IE64005B1 (en)	1995-06-28
RU95110767A (ru)	1997-06-10
EP0462277B1 (en)	1995-06-07
HU211229A9 (en)	1995-11-28
ATE123498T1 (de)	1995-06-15
NZ232813A (en)	1992-08-26
DE69019962T2 (de)	1995-11-23
AU629314B2 (en)	1992-10-01
WO1990010651A1 (fr)	1990-09-20
NO913546D0 (no)	1991-09-09
HU212513B (en)	1996-07-29
NO180796B (no)	1997-03-17
EP0462277A1 (en)	1991-12-27

Publication	Publication Date	Title
JPH0768272B1 (ja)	1995-07-26
GR3035627T3 (en)	2001-06-29	A mammalian cytokine, il-11.
CS40289A3 (en)	1992-01-15	Method of vital viral cultures maintenance
AU574350B2 (en)	1988-07-07	Human nerve growth factor by recombinant technology
AU4283389A (en)	1990-04-05	Modified viral glycoproteins, diagnostic and therapeutic uses therefore
NZ221119A (en)	1990-08-28	Proteins with factor viii activity produced by microorganisms produced by genetic engineering
GR3033146T3 (en)	2000-08-31	Modified polypeptides with increased biological activity
DE3586697D1 (en)	1992-11-05	Aktive thymopentin-analoga.
GB8811115D0 (en)	1988-06-15	Tomatoes
AU6927087A (en)	1987-09-17	1,2,3,4-tetrahydro-6-substituted-4-aryl(or heterocyclo)-3- substituted-2-thioxo(or oxo)-5-pyrimidinecarboxylic acids and esters
ZA871262B (en)	1987-09-30	1,2,3,4-tetrahydro-6-substituted-4-aryl(or heterocyclo)-3-substituted-2-thioxo(or oxo)-5-pyrimidinecarboxylic acids and esters
EP0276120A3 (en)	1989-10-04	Treatment of certain leukemias with a combination of gamma interferon and alpha interferon
IL81751A0 (en)	1987-10-20	Fermentation of bacteria at high productivities
ZA874693B (en)	1988-01-04	Inter-ply adhesion between saran and linear ethylene copolymers
IT8820916A0 (it)	1988-06-09	Procedimento ed impianto per la coltura di microorganismi.
AU95041S (en)	1987-01-29	Leg guard strap attachment for cricket pad
GB8910802D0 (en)	1989-06-28	Genetically engineered processing or micro-organism cultures and dna therefor
CU21576A1 (en)	1987-07-22	Procedure and culture media for the production of powdered inocule of aspergillus oryzae
AU103797S (en)	1989-05-04	Stationery retainer
AU91636S (en)	1986-03-13	Head support
AU107606S (en)	1990-05-14	Gutter
GB8816691D0 (en)	1988-08-17	Viral gene & enzyme
JO1609B1 (en)	1990-07-01	Secret locker for keeping jewelry
EP0153336A4 (en)	1985-11-25	AMPLIFICATION OF ANTIBIOTIC AND / OR ANTITUMOR ACTIVITY.
AU107701S (en)	1990-05-28	Cooktop

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