FI102681B - Menetelmä glykoproteiinin valmistamiseksi - Google Patents
Menetelmä glykoproteiinin valmistamiseksiInfo
- Publication number
- FI102681B FI102681B FI914234A FI914234A FI102681B FI 102681 B FI102681 B FI 102681B FI 914234 A FI914234 A FI 914234A FI 914234 A FI914234 A FI 914234A FI 102681 B FI102681 B FI 102681B
- Authority
- FI
- Finland
- Prior art keywords
- glycoprotein
- cells
- preparation
- fibroblasts
- accelerating
- Prior art date
Links
- 102000003886 Glycoproteins Human genes 0.000 title abstract 2
- 108090000288 Glycoproteins Proteins 0.000 title abstract 2
- 230000000259 anti-tumor effect Effects 0.000 abstract 2
- 230000024932 T cell mediated immunity Effects 0.000 abstract 1
- 210000004204 blood vessel Anatomy 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000004069 differentiation Effects 0.000 abstract 1
- 210000002889 endothelial cell Anatomy 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 210000002950 fibroblast Anatomy 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 230000002440 hepatic effect Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 208000032839 leukemia Diseases 0.000 abstract 1
- 210000004738 parenchymal cell Anatomy 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 239000006228 supernatant Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5863189 | 1989-03-10 | ||
JP669290 | 1990-01-16 | ||
PCT/JP1990/000314 WO1990010651A1 (fr) | 1989-03-10 | 1990-03-09 | Glycoproteine humaine, facteur physiologiquement actif la contenant, et preparation pharmaceutique le contenant en tant qu'ingredient actif |
Publications (3)
Publication Number | Publication Date |
---|---|
FI914234A0 FI914234A0 (fi) | 1991-09-09 |
FI102681B1 FI102681B1 (fi) | 1999-01-29 |
FI102681B true FI102681B (fi) | 1999-01-29 |
Family
ID=26340889
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI914234A FI102681B (fi) | 1989-03-10 | 1991-09-09 | Menetelmä glykoproteiinin valmistamiseksi |
Country Status (17)
Country | Link |
---|---|
US (2) | US5587359A (fi) |
EP (1) | EP0462277B1 (fi) |
JP (1) | JPH0768272B1 (fi) |
KR (1) | KR960009054B1 (fi) |
AT (1) | ATE123498T1 (fi) |
AU (1) | AU629314B2 (fi) |
CA (1) | CA2049017C (fi) |
DE (1) | DE69019962T2 (fi) |
DK (1) | DK0462277T3 (fi) |
ES (1) | ES2075199T3 (fi) |
FI (1) | FI102681B (fi) |
HU (2) | HU212513B (fi) |
IE (1) | IE64005B1 (fi) |
NO (1) | NO180796C (fi) |
NZ (1) | NZ232813A (fi) |
RU (1) | RU2113480C1 (fi) |
WO (1) | WO1990010651A1 (fi) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5362716A (en) * | 1989-12-27 | 1994-11-08 | The United States Of America As Represented By The Department Of Health And Human Services | Methods for stimulating hematopoietic progenitors using hepatocyte growth factor and lymphokines |
EP0859009B1 (en) * | 1990-06-11 | 2005-11-30 | Toshikazu Nakamura | Recombinant human hepatocyte growth factor and method for production thereof |
ATE178354T1 (de) * | 1990-07-13 | 1999-04-15 | Snow Brand Milk Products Co Ltd | Plasmid das für die aminosäuresequenz von tcf-ii kodierende dns enthalt, transformierte zelle und produktion einer physiologisch aktiven substanz mit ihrer verwendung |
EP0571387B1 (en) * | 1990-09-14 | 2003-12-17 | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce | A non-mitogenic competitive hgf antagonist |
US5821223A (en) * | 1990-09-14 | 1998-10-13 | The United States Of America As Represented By The Department Of Health And Human Services | Method of stimulating cell growth with a novel broad spectrum human lung fibroblast-derived mitogen |
JP3200609B2 (ja) * | 1990-12-28 | 2001-08-20 | 敏一 中村 | 上皮細胞増殖促進剤 |
JPH0597A (ja) * | 1991-06-21 | 1993-01-08 | Snow Brand Milk Prod Co Ltd | 新規抗tcf−iiモノクローナル抗体及びそれを用いるtcf−iiの測定方法 |
CA2100720C (en) | 1992-07-16 | 2003-03-11 | Hiroaki Masunaga | Medicinal composition comprising tcf-ii |
DK0653211T3 (da) * | 1992-07-16 | 2002-05-06 | Daiichi Seiyaku Co | Blodkoagulationsnormalisator indeholdende TCF-II som aktiv bestanddel |
CA2130561A1 (en) * | 1992-12-28 | 1994-07-07 | Kyoji Yamaguchi | Modified tcf |
JP3552240B2 (ja) * | 1993-02-23 | 2004-08-11 | 第一製薬株式会社 | 高濃度tcf製剤 |
US5837676A (en) * | 1993-10-18 | 1998-11-17 | Long Island Jewish Medical Center | Use of scatter factor to enhance angiogenesis |
JP2747979B2 (ja) * | 1994-08-19 | 1998-05-06 | 雪印乳業株式会社 | ヒト由来の糖蛋白質からなる生理活性因子を有効成分とする医薬 |
JPH08176007A (ja) * | 1994-12-27 | 1996-07-09 | Snow Brand Milk Prod Co Ltd | 脂質代謝異常治療剤 |
WO1996020214A1 (en) * | 1994-12-27 | 1996-07-04 | Snow Brand Milk Products Co., Ltd. | Tcf mutant |
AU4027601A (en) * | 1995-07-11 | 2001-07-26 | Snow Brand Milk Products Co., Ltd. | Lyophilized HGF preparations |
JP3927248B2 (ja) * | 1995-07-11 | 2007-06-06 | 第一製薬株式会社 | Hgf凍結乾燥製剤 |
JP4006058B2 (ja) | 1997-03-11 | 2007-11-14 | 第一三共株式会社 | 多臓器不全予防及び/又は治療剤 |
EP0950416B1 (en) * | 1997-03-14 | 2006-11-02 | Daiichi Pharmaceutical Co., Ltd. | Use of TCF-II for the treatment of cancer related body weight loss, anaemia and TNF elevation |
JPH1129493A (ja) * | 1997-07-14 | 1999-02-02 | Snow Brand Milk Prod Co Ltd | 放射線障害予防及び/又は治療剤 |
JPH11269091A (ja) * | 1998-03-19 | 1999-10-05 | Snow Brand Milk Prod Co Ltd | 敗血症予防及び/又は治療剤 |
CN1352087A (zh) * | 2000-11-02 | 2002-06-05 | 上海博德基因开发有限公司 | 一种新的多肽——人糖蛋白42和编码这种多肽的多核苷酸 |
KR100562824B1 (ko) * | 2002-03-20 | 2006-03-23 | 주식회사 바이로메드 | 유전자 발현효율이 높으며 간세포 성장인자의 두 가지이형체를 동시에 발현하는 하이브리드 간세포 성장인자유전자 |
US7563810B2 (en) | 2002-11-06 | 2009-07-21 | Celgene Corporation | Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases |
US8034831B2 (en) | 2002-11-06 | 2011-10-11 | Celgene Corporation | Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies |
CN100417412C (zh) * | 2003-03-28 | 2008-09-10 | 威海赛洛金药业有限公司 | 促肝细胞生长素注射液及制备方法和应用 |
JP4728807B2 (ja) * | 2003-09-03 | 2011-07-20 | 敏一 中村 | ヒト組換えhgfを含有する皮膚潰瘍予防治癒剤 |
CA2640010A1 (en) * | 2006-01-25 | 2007-08-02 | Octapharma Ag | Purification and use of a factor for supporting wound healing |
WO2008136183A1 (ja) * | 2007-04-28 | 2008-11-13 | Applied Cell Biotechnologies, Inc. | 皮膚または歯肉の軟組織の欠損を補修するための組成物,及び自己線維芽細胞の培養方法 |
US20090202606A1 (en) * | 2008-01-25 | 2009-08-13 | Viromed Co., Ltd. | Treatment and Prevention of Cardiac Conditions Using Two or More Isoforms of Hepatocyte Growth Factor |
ES2556711T3 (es) * | 2008-04-09 | 2016-01-19 | Viromed Co., Ltd. | Formulaciones liofilizadas de ADN para el aumento de la expresión del ADN plasmídico |
MX375916B (es) | 2013-10-22 | 2025-03-07 | Helixmith Co Ltd | Composicion para prevenir o tratar la esclerosis lateral amiotrofica usando dos o mas isoformas del factor de crecimiento de hepatocito. |
WO2015166885A1 (ja) * | 2014-04-28 | 2015-11-05 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | Hgf凍結乾燥製剤 |
JP6281992B2 (ja) | 2014-09-10 | 2018-02-21 | クリングルファーマ株式会社 | 神経疾患の治療に適したhgf製剤 |
JP6861201B2 (ja) | 2016-03-17 | 2021-04-21 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 活性型肝細胞増殖因子(hgf)の製造方法 |
JP7212230B2 (ja) | 2018-07-19 | 2023-01-25 | ヘリックスミス カンパニー, リミテッド | ネイキッドdna遺伝子療法のための凍結乾燥した薬剤学的組成物 |
AU2022272740A1 (en) | 2021-05-14 | 2023-11-02 | Claris Biotherapeutics, Inc. | Compositions of growth factor for the treatment of eye disease |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58148826A (ja) * | 1982-02-26 | 1983-09-05 | Mochida Pharmaceut Co Ltd | 糖蛋白質および腫瘍治療剤 |
JP2564486B2 (ja) * | 1986-07-14 | 1996-12-18 | 修治 橋本 | 肝細胞増殖因子 |
US5037644A (en) * | 1986-10-27 | 1991-08-06 | Cetus Corporation | Pharmaceutical compositions of recombinant interleukin-2 and formulation processes |
DE3643182A1 (de) * | 1986-12-18 | 1988-06-30 | Behringwerke Ag | Arzneimittel enthaltend das gewebeprotein pp4, verfahren zur herstellung von pp4 und zu seiner pasteurisierung sowie die verwendung von pp4 |
JPS6410998A (en) * | 1986-12-22 | 1989-01-13 | Green Cross Corp | Tumor cell inhibitory factor |
JPS63243032A (ja) * | 1987-03-27 | 1988-10-07 | Green Cross Corp:The | トロンビンの加熱処理方法 |
DE3729863A1 (de) * | 1987-09-05 | 1989-03-16 | Boehringer Mannheim Gmbh | Stabilisierte erythropoietin-lyophilisate |
JPH0741891B2 (ja) * | 1987-08-26 | 1995-05-10 | 凸版印刷株式会社 | 容器素材成形装置 |
FI80741C (fi) * | 1987-10-29 | 1990-07-10 | Laennen Tehtaat Oy | Modifierat papper. |
ATE178354T1 (de) * | 1990-07-13 | 1999-04-15 | Snow Brand Milk Products Co Ltd | Plasmid das für die aminosäuresequenz von tcf-ii kodierende dns enthalt, transformierte zelle und produktion einer physiologisch aktiven substanz mit ihrer verwendung |
-
1990
- 1990-03-06 NZ NZ232813A patent/NZ232813A/en unknown
- 1990-03-09 CA CA002049017A patent/CA2049017C/en not_active Expired - Lifetime
- 1990-03-09 RU RU95110767A patent/RU2113480C1/ru active
- 1990-03-09 AT AT90904429T patent/ATE123498T1/de not_active IP Right Cessation
- 1990-03-09 DK DK90904429.9T patent/DK0462277T3/da active
- 1990-03-09 AU AU51774/90A patent/AU629314B2/en not_active Expired
- 1990-03-09 KR KR1019910701058A patent/KR960009054B1/ko not_active IP Right Cessation
- 1990-03-09 DE DE69019962T patent/DE69019962T2/de not_active Expired - Lifetime
- 1990-03-09 EP EP90904429A patent/EP0462277B1/en not_active Expired - Lifetime
- 1990-03-09 IE IE86390A patent/IE64005B1/en not_active IP Right Cessation
- 1990-03-09 ES ES90904429T patent/ES2075199T3/es not_active Expired - Lifetime
- 1990-03-09 WO PCT/JP1990/000314 patent/WO1990010651A1/ja active IP Right Grant
- 1990-03-09 HU HU902330A patent/HU212513B/hu unknown
- 1990-03-09 JP JP2504271A patent/JPH0768272B1/ja not_active Expired - Lifetime
-
1991
- 1991-09-09 NO NO913546A patent/NO180796C/no not_active IP Right Cessation
- 1991-09-09 FI FI914234A patent/FI102681B/fi active
-
1994
- 1994-09-12 US US08/304,419 patent/US5587359A/en not_active Expired - Lifetime
-
1995
- 1995-06-02 HU HU95P/P00149P patent/HU211229A9/hu unknown
-
1996
- 1996-03-19 US US08/617,621 patent/US6333309B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
FI102681B1 (fi) | 1999-01-29 |
EP0462277A1 (en) | 1991-12-27 |
WO1990010651A1 (fr) | 1990-09-20 |
KR960009054B1 (ko) | 1996-07-10 |
DE69019962T2 (de) | 1995-11-23 |
EP0462277A4 (en) | 1992-08-12 |
AU5177490A (en) | 1990-10-09 |
ES2075199T3 (es) | 1995-10-01 |
DE69019962D1 (de) | 1995-07-13 |
HU211229A9 (en) | 1995-11-28 |
NZ232813A (en) | 1992-08-26 |
DK0462277T3 (da) | 1995-10-30 |
IE64005B1 (en) | 1995-06-28 |
NO913546L (no) | 1991-11-11 |
US6333309B1 (en) | 2001-12-25 |
HU212513B (en) | 1996-07-29 |
NO180796C (no) | 1997-06-25 |
EP0462277B1 (en) | 1995-06-07 |
RU2113480C1 (ru) | 1998-06-20 |
JPH0768272B1 (fi) | 1995-07-26 |
FI914234A0 (fi) | 1991-09-09 |
KR920701256A (ko) | 1992-08-11 |
ATE123498T1 (de) | 1995-06-15 |
HU902330D0 (en) | 1991-12-30 |
NO180796B (no) | 1997-03-17 |
CA2049017C (en) | 1998-10-27 |
IE900863L (en) | 1990-09-10 |
NO913546D0 (no) | 1991-09-09 |
RU95110767A (ru) | 1997-06-10 |
US5587359A (en) | 1996-12-24 |
CA2049017A1 (en) | 1990-09-11 |
HUT58797A (en) | 1992-03-30 |
AU629314B2 (en) | 1992-10-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Transfer of assignment of patent |
Owner name: ATLAS PHARMACEUTICALS INC. Free format text: ATLAS PHARMACEUTICALS INC. |